Protein Purification

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Miniaturization of small-scale protein purification reduces time and allows for parallel processing of samples for increased statistical significance and greater breadth of variables.

Our workstations were developed as intuitive and flexible automated platforms designed to perform parallel small-scale analytical protein purification and are predictive of larger scale purification workflows. Preprogrammed methods automate commercially available ion exchange and affinity chromatography solutions, including miniaturized chromatography columns, resin-packed pipette tips and resin-filled microtiter vacuum filtration plates.

The LabChip^® GXII Touch offers rapid quantification and quality control throughout the protein purification workflow. For example, automating the characterization process allows multiple, critical quality attributes to be obtained significantly faster. Researchers can now screen for optimal protein characteristics earlier in the process, and integrate Quality by Design initiatives into their protein therapeutic development workflow.

For Research Use Only. Not for use in diagnostic procedures.

Automated Small Scale Purification

The JANUS^® G3 BioTx automated workstations enable consistent small scale protein purification and sample prep for analytical protein characterization required to support quality by design experimentation in both upstream and downstream processes.

Suggested Products

JANUS G3 BioTx Pro Plus Workstation JANUS G3 BioTX^™ Pro Workstation

Protein Characterization

The LabChip GXII Touch delivers comparable results to traditional capillary electrophoresis with as much as a 70x increase in throughput and as few as forty seconds per sample. Used in protein purification workflow, the platform can characterize proteins in reduced and non-reduced samples for critical quality attributes:

Purity
Titre
Glycan screening
mAb charge heterogeneity
Fragmentation

Suggested Products

LabChip GXII Touch HT Protein Characterization System

LabChip Protein Assays

Provide rapid (48 seconds / sample) and reproducible purity analysis for therapeutic proteins and detection and visualization of low concentration impurity peaks down to 5 ng/µL.

Suggested Products

Protein Clear^™ HR Reagent Kit Protein Express Assay Reagent Kit Glycan Profiling Assay Reagent Kit Protein Charge Variant Reagent Kit Protein Low Molecular Weight Assay Reagent Kit Protein Pico Assay Reagent Kit

Microvolume Protein Spectroscopy

A microplate reader giving full spectrum scans of up to 96 samples in less than six minutes from sample volumes as low as 1 µL, allowing rapid full spectrum assessment of sample impurities before expensive downstream processing has begun.

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Consumables (9)
Instruments (4)
Reagents (6)

Application

DNA/RNA Quantitation (1)
DNA/RNA Quantitation and QC (3)
Protein Analysis (9)
Protein-nucleic acid interactions (1)

Product Brand Name

DropletQuant / LabChip DS (3)
JANUS (2)
LabChip GXII (10)

Sample Type

DNA / RNA (2)
Protein (10)

Automation Compatible

Yes (2)

Depth

33.0 in (2)
46.0 cm (1)
49.0 cm (1)

Model Compatible With

LabChip GXII Touch 24 (1)
LabChip GXII Touch HT (1)

1-12 of 19 Products & Services

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JANUS G3 BioTx Pro Plus Workstation

YJM8MP1

The JANUS^® G3 Bio Tx Pro Plus offers full walk-away automation for high-throughput process development, enabling more data from precious starting materials and limited resources.
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JANUS G3 BioTX Pro Workstation

YJS80P1
The affordable and compact JANUS^® G3 BioTx Pro Automated Workstation enables consistent, time-saving small-scale protein purification and sample preparation for analytical protein characterization required to support quality by design experimentation in both upstream and downstream processes.

Ideal Workstation for:
- Expression optimization
- Cell line selection
- Purification process development
- Bioanalytical sample preparation
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LabChip GXII Touch Protein Characterization System

CLS138161 , CLS138160

The LabChip^® GXII Touch^™ protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Leveraging microfluidic electrophoretic separation technology, the LabChip^® GXII Touch^™ system enables rapid characterization with minimal sample preparation setup and sample input volume.
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DropletQuant UV-VIS Spectrophotometer

CLS146933

The DropletQuant^® UV-VIS spectrophotometer complements PerkinElmer's existing LabChip^® microfluidics instrument portfolio, providing electrophoretic separation and analysis of nucleic acids and proteins.
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Protein Express Assay Reagent Kit

CLS960008

Supports reagent use protocols for small or large batch sizes. Contains enough reagent for 4 primes to run large batch sizes up to 384 and 8 primes to run batch sizes of 48 or fewer.

List Price : 352.00 USD
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ProteinEXact Assay Reagent Kit

CLS150466

The LabChip^® GXII Touch Capillary Electrophoresis System utilizes a microfluidic chip to rapidly characterize protein samples from 24-, 96- or 384-well plates. The technology automatically stains distains, electrophoretically separates and analyzes the protein samples. Use the system software to automatically analyze data which is immediately available for review or reporting in virtual gel, electropherogram graph or table summary form.

List Price : 474.00 USD
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Protein Clear^™ HR Reagent Kit

CLS960014

The LabChip^® GXII Touch microfluidics Protein Clear HR assay provides rapid (65 seconds/ sample) high-resolution protein purity analysis for monoclonal antibody (mAb) process development formulation, stability and manufacturing quality control. Enabling the detection and visualization of impurities within a sample, down to 5 ng/µL .

List Price : 628.00 USD
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Protein Pico Assay Reagent Kit

760498

The PerkinElmer LabChip Pico Protein reagent provides a fast and easy way to analyze protein samples between 14-200 kDa requiring sensitivity equivalent to Silver Stain levels. Protein detection for concentrations as low as 10 pg/ul, with a linear dynamic range of four orders of magnitude.

Reagent designed for 400 sample capacity. Protein Express LabChip is sold separately (P/N 760499, LabChip GXII and LabChip GXII touch HT); (P/N CLS138950 for LabChip GXII Touch 24).

List Price : 1628.00 USD
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Protein Low Molecular Weight Assay Reagent Kit

760573

The PerkinElmer LabChip Low Molecular Weight Protein assay provides a fast and easy way to analyze protein samples between 5-80 kDa.

List Price : 342.00 USD
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Protein Charge Variant Reagent Kit

CLS760670

The LabChip^® protein charge variant kit is a microfluidic assay used to measure relative percentages of variant in recombinant monoclonal antibody samples.

List Price : 420.00 USD
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DropletQuant / LabChip DS DropPlate16-D+ Chips

CLS135134

DropPlate16-D+ Chips, Box of 30 dual-path length chamber chips. Each chip can perform up to 16 sample reads.

List Price : 194.00 USD
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Glycan Profiling Assay Release and Labeling Kit

760523

ProfilerPro® Glycan Profiling Kit designed for the LabChip GXII microfluidic system provides a fast, economically efficient means to assess the main glycoforms of IgG and related proteins.

List Price : 1418.00 USD