PerkinElmer

Protein-Protein Interaction Research Reagents

OF

The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study large protein interactions is increasingly important.

Notable, our Alpha technology is a highly flexible, homogenous, no-wash assay ideal for the measurement of protein interactions and complexes as large as 200 nm in size. A bead-based proximity assay, Alpha technology offers the possibility to assay many biological targets including enzymes, receptor-ligand interactions, low-affinity interactions, second messenger levels, DNA, RNA, proteins, peptides, sugars and small molecules.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Products & Services (109)
Filters:

Filters :

Assay Target
  • 4-1BB (1)
  • 4-1BBL (1)
  • EGF (2)
  • EGFR (3)
  • FCGR1 (1)
  • FCGR2A (2)
  • FCGR2B (1)
  • FCGR3A (2)
  • LDLR (1)
  • MMP-7 (1)
  • PCSK9 (1)
  • PD-1 (2)
  • PD-L1 (2)
  • TNFα (2)
  • TNRFR1 (1)
  • TNRFR3 (1)
Target Species
  • Human (11)
  • Mouse (1)
Application
  • Antibody binding (1)
  • Enzymatic (5)
  • Isotyping (1)
  • Multiplexing (2)
  • Protein Analysis & Detection (49)
  • Protein-nucleic acid interactions (4)
  • Protein-protein interactions (98)
Therapeutic Area
  • Biologics/Bioprocess (6)
  • Cancer (7)
  • Cardiovascular (1)
  • Inflammation (2)
Product Brand Name
  • Alpha (7)
  • AlphaLISA (43)
  • AlphaPlex (16)
  • AlphaScreen (12)
  • DELFIA (7)
  • LANCE (10)
  • LANCE SureLight (4)
  • LANCE Ultra (11)
Detection Method
  • Alpha (63)
  • DELFIA TRF (7)
  • Time-Resolved Fluorescence (TRF) (26)
  • TR-FRET (19)
Antibody Conjugates
  • Anti-6X His (7)
  • Anti-bovine IgA (1)
  • Anti-c-Myc (4)
  • Anti-C-tag (3)
  • Anti-DIG (2)
  • Anti-DNP (2)
  • Anti-FITC (3)
  • Anti-FLAG (6)
  • Anti-GFP (2)
  • Anti-goat IgG (1)
  • Anti-GST (5)
  • Anti-HA (4)
  • Anti-HRP (2)
  • Anti-human IgG (3)
  • Anti-MBP (1)
  • Anti-mouse IgG (3)
  • Anti-rabbit IgG (2)
  • Anti-rat IgG (2)
  • Anti-V5 (3)
  • Glutathione (3)
  • Nickel chelate (1)
  • Protein A (5)
  • Protein G (1)
  • Protein L (1)
  • Strep-Tactin (1)
  • Streptavidin (11)
  • Streptavidin/Anti-c-Myc (1)
  • Streptavidin/Anti-DIG (1)
  • Streptavidin/Anti-FITC (1)
  • Streptavidin/Anti-FLAG (1)
  • Streptavidin/Anti-GST (1)
  • Streptavidin/Anti-HA (1)
  • Streptavidin/Anti-mouse IgG (1)
  • Streptavidin/Anti-rabbit IgG (1)
  • Streptavidin/Nickel chelate (1)
  • Streptavidin/Protein A (1)
  • Unconjugated (2)
Fluorophore
  • Eu-N1 (5)
  • Eu-W1024 (9)
  • Eu-W8044 (1)
  • Sm-N1 (1)
  • SureLight APC (4)
  • Tb-N1 (1)
  • ULight (8)
Assay points(200-50,000)
  • 100 (5)
  • 10000 (11)
  • 500 (26)
  • 5000 (15)
  • 50000 (10)
Assay Target Class
  • Cytokine (2)
  • Fc-receptor (6)
  • Protein (10)
Automation Compatible
  • Yes (109)
Experimental Type
  • In vitro (74)
Format
  • Microplates (80)

1-12 of 109 Products & Services

Sort by

  • AlphaScreen FLAG (M2) Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-FLAG conjugated AlphaScreen Acceptor beads. 
    Price Range : 188.00 USD - 14400.00 USD
  • AlphaLISA immunoassay kits

    FCGR2B/CD32b AlphaLISA Binding Kit

    This kit is designed for the detection of binding between FCGR2B (CD32b) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
    Price Range : 2213.00 USD - 11100.00 USD
  • ULight anti-FITC

    ULight™ labeled anti-FITC antibody for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.
    Price Range : 446.00 USD - 11300.00 USD
  • AlphaScreen GST Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-GST conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
    Price Range : 188.00 USD - 14400.00 USD
  • Nickel Chelate AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to nickel chelate. These beads can be used to capture His-tagged proteins and peptides.
    Price Range : 613.00 USD - 25200.00 USD
  • Anti-rabbit IgG (Fc specific) AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-rabbit IgG antibody. These beads can be used to capture rabbit IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
    Price Range : 613.00 USD - 25200.00 USD
  • LANCE Ultra ULight™-Streptavidin

    Streptavidin labeled with ULight™ dye.
    Price Range : 330.00 USD - 6500.00 USD
  • Assay principle for AlphaLISA binding assay

    4-1BB/4-1BBL (human) AlphaLISA Binding Kit

    The AlphaLISA® 4-1BB/4-1BBL binding kit is designed for the detection of binding activity between human 4-1BB and 4-1BBL, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2229.00 USD - 11100.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA® Eu-N1 Anti-HA

    Europium-labeled anti-HA antibody for binding HA-tagged proteins in DELFIA® time-resolved fluorescence (TRF) assays. The anti-HA antibody is a purified IgG2b subclass of mouse monoclonal antibody. It recognizes the epitope sequence (YPYDVPDYA) derived from the human influenza hemagglutinin (HA) protein.
    Price Range : 655.00 USD - 6300.00 USD
  • AlphaLISA immunoassay kits

    MMP-7 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human MMP7 enables the detection and quantitation of human pro- and active MMP-7 (hMMP-7) in serum, buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 465.00 USD - 10200.00 USD
  • AlphaPlex-545-antibody-bead2

    Anti-HA AlphaPlex 545 (Tb) Acceptor Beads

    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-HA (hemaglutinin) antibody. These beads can be used to capture HA-tagged proteins and peptides.
    Price Range : 613.00 USD - 25200.00 USD
  • AlphaPlex Samarium Acceptor Beads

    Protein A AlphaPlex™ 645 (Sm) Acceptor Beads

    AlphaPlex-645 (Samarium) Acceptor beads conjugated to Protein A. These beads are used to capture immunoglobulins through their heavy chain (Fc region) allowing optimal orientation and antigen detection. Protein A has higher affinity for rabbit, pig, dog and cat IgG.
    Price Range : 612.00 USD - 25100.00 USD
  • Jump to: