PerkinElmer

Protein-Protein Interaction Research Reagents

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The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study large protein interactions is increasingly important.

Notable, our Alpha technology is a highly flexible, homogenous, no-wash assay ideal for the measurement of protein interactions and complexes as large as 200 nm in size. A bead-based proximity assay, Alpha technology offers the possibility to assay many biological targets including enzymes, receptor-ligand interactions, low-affinity interactions, second messenger levels, DNA, RNA, proteins, peptides, sugars and small molecules.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Products & Services (104)
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Assay Target
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  • Protein-protein interactions (90)
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  • AlphaLISA (52)
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Automation Compatible
  • Yes (104)
Experimental Type
  • In vitro (73)
Format
  • Microplates (74)

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1-25 of 104 Products & Services

  • Glutathione AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to glutathione. These beads can be used to capture GST-tagged proteins and peptides.
    Price Range : 736.00 USD - 30200.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA Sm-N1 Streptavidin

    Samarium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
    Price Range : 347.00 USD - 2367.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-GST AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-GST antibody. These beads can be used to capture GST-tagged proteins and peptides in AlphaLISA no-wash assays.
    Price Range : 736.00 USD - 30200.00 USD
  • Alpha Donor Bead Antibody Conjugated

    Anti-DNP Alpha Donor Beads

    Alpha Donor beads conjugated to anti-DNP antibody. These beads can be used to capture DNP-labeled proteins, peptides, and small molecules.
    Price Range : 1995.00 USD - 23300.00 USD
  • FCGR2B/CD32b AlphaLISA Binding Kit

    This kit is designed for the detection of binding between FCGR2B (CD32b) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
    Price Range : 2659.00 USD - 13300.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA® Eu-N1 Anti-HA

    Europium-labeled anti-HA antibody for binding HA-tagged proteins in DELFIA® time-resolved fluorescence (TRF) assays. The anti-HA antibody is a purified IgG2b subclass of mouse monoclonal antibody. It recognizes the epitope sequence (YPYDVPDYA) derived from the human influenza hemagglutinin (HA) protein.
    Price Range : 712.00 USD - 6900.00 USD
  • AlphaLISA Binding

    FCGR3A/CD16a (176Val/V158) AlphaLISA Binding Kit

    This kit is designed for the detection of binding activity between human FCGR3A (176Val) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
    Price Range : 871.00 USD - 13300.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-V5 AlphaLISA Acceptor beads

    AlphaLISA® Acceptor beads conjugated to anti-V5 antibody. The mouse monoclonal antibody detects proteins tagged with the V5 14-amino-acid tag (the 9-amino-acid tag has also been successfully bound by the antibody). 
    Price Range : 736.00 USD - 30200.00 USD
  • FCGR1/CD64 AlphaLISA Binding Kit

    This kit is designed for the detection of binding between FCGR1 (CD64) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
    Price Range : 2659.00 USD - 13300.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-goat IgG (Fc specific) AlphaLISA® Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-goat IgG antibody. These beads can be used to capture goat IgG antibodies. The antibody is Fc-specific, and is a rabbit polyclonal F(ab')2 fragment.
    Price Range : 736.00 USD - 30200.00 USD
  • PD-1/PD-L1 (cyno) AlphaLISA Binding Kit

    The AlphaLISA® cyno PD-1/PD-L1 binding kit is designed for the detection of binding activity between cyno PD-1 and PD-L1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.

    Price Range : 2659.00 USD - 13200.00 USD
  • Europium-labeled antibody for LANCE assays

    LANCE Eu-W1024 anti-FLAG

    Eu-W1024 labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.
    Price Range : 456.00 USD - 10200.00 USD
  • Alpha Donor Bead Antibody Conjugated

    Anti-DIG Alpha Donor beads

    Alpha Donor beads conjugated to anti-DIG (digoxin) antibody. This bead can be used to capture Dig-labeled biomolecules for Alpha no-wash assays.
    Price Range : 644.00 USD - 10900.00 USD
  • AlphaLISA Binding

    TNFα/TNFR1 (human) AlphaLISA Binding Kit

    The AlphaLISA® human TNFα/TNFR1 binding kit is designed for the detection of binding activity between human TNFα and TNFR1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2659.00 USD - 13700.00 USD
  • AlphaScreen Anti-Species

    AlphaScreen Histidine (Nickel Chelate) Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and nickel chelate (Ni-NTA) AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
    Price Range : 225.00 USD - 17300.00 USD
  • AlphaPlex Acceptor Bead 645 Antibody

    Anti-Human IgG AlphaPlex 645 (Sm) Acceptor beads

    AlphaPlex™-645 (Samarium) Acceptor beads conjugated to anti-human IgG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 736.00 USD - 30200.00 USD
  • ULight anti-FITC

    ULight™ labeled anti-FITC antibody for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.
    Price Range : 486.00 USD - 12300.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-c-myc AlphaLISA® Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-c-myc antibody. These beads can be used to capture c-myc-tagged proteins and peptides in AlphaLISA no-wash assays.
    Price Range : 736.00 USD - 30200.00 USD
  • LANCE Ultra ULight™-anti-GST

    Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.
    Price Range : 534.00 USD - 12600.00 USD
  • AlphaLISA Binding

    PD-1/PD-L1 (human) AlphaLISA Binding Kit

    The AlphaLISA® human PD-1/PD-L1 binding kit is designed for the detection of binding activity between human PD-1 and PD-L1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 871.00 USD - 12200.00 USD
  • Alpha Donor Bead Antibody Conjugated

    Anti-rat IgG Alpha Donor Beads

    Alpha Donor beads conjugated to anti-rat IgG antibody. This bead can be used to capture rat IgG antibodies for Alpha no-wash protein detection, antibody detection, antibody binding, and other applications.
    Price Range : 643.00 USD - 10900.00 USD
  • Protein A AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to Protein A. These beads can be used to capture antibodies that associate with Protein A.
    Price Range : 736.00 USD - 30200.00 USD
  • PD-1/PD-L2 (human) AlphaLISA Binding Kit

    The AlphaLISA® human PD-1/PD-L2 binding kit is designed for the detection of binding activity between human PD-1 and PD-L2, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2659.00 USD - 13200.00 USD
  • AlphaLISA Binding

    PD-1/PD-L1 (mouse) AlphaLISA Binding Kit

    The AlphaLISA® mouse PD-1/PD-L1 binding assay enables development and characterization of small and large molecule anti-mouse PD-1 or PD-L1 reagents for in vitro and in vivo studies, testing of other putative binding ligands such as PD-L2 or characterization of ligand subregions for their ability to block binding, and determination of mouse cross-reactivity of anti-human PD-1 or PD-L1 reagents using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 2659.00 USD - 13200.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-HA AlphaLISA Acceptor Beads

    AlphaLISA Acceptor beads conjugated to anti-HA (hemagglutinin) antibody. These beads can be used to capture HA-tagged proteins and peptides.
    Price Range : 736.00 USD - 30300.00 USD
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