PerkinElmer

Protein-Protein Interaction Research Reagents

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The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study large protein interactions is increasingly important.

Notable, our Alpha technology is a highly flexible, homogenous, no-wash assay ideal for the measurement of protein interactions and complexes as large as 200 nm in size. A bead-based proximity assay, Alpha technology offers the possibility to assay many biological targets including enzymes, receptor-ligand interactions, low-affinity interactions, second messenger levels, DNA, RNA, proteins, peptides, sugars and small molecules.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Products & Services (105)
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Assay Target
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  • Alpha (7)
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  • Yes (105)
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  • In vitro (73)
Format
  • Microplates (74)

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1-25 of 105 Products & Services

  • PD-1/PD-L1 (cyno) AlphaLISA Binding Kit

    The AlphaLISA® cyno PD-1/PD-L1 binding kit is designed for the detection of binding activity between cyno PD-1 and PD-L1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.

    Price Range : 2659.00 USD - 13200.00 USD
  • Assay AlphaPlex acceptor bead 545

    Glutathione AlphaPlex™ 545 Acceptor Beads

    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to glutathione, for use in Alpha no-wash multiplexing assays.
    Price Range : 736.00 USD - 30200.00 USD
  • Europium-labeled antibody for LANCE assays

    Eu-anti-V5 (LANCE TR-FRET)

    Europium-labeled anti-V5 antibody, for capturing V5-tagged proteins in LANCE® TR-FRET assays. This Europium-labeled reagent can be used to capture V5-tagged proteins and peptides, and can be used in conjunction with LANCE® ULight or SureLight APC reagents to create TR-FRET no-wash assays for protein-protein interaction, protein detection, and enzymatic studies.
    Price Range : 351.00 USD - 9900.00 USD
  • Protein A AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to Protein A. These beads can be used to capture antibodies that associate with Protein A.
    Price Range : 736.00 USD - 30200.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-GFP AlphaLISA® Acceptor beads

    AlphaLISA® Acceptor beads conjugated to anti-GFP antibody. The antibody is a mouse monoclonal antibody that recognizes wildtype and recombinant GFP (rGFP), and cross-reacts with eGFP. These beads can be used to capture GFP-tagged proteins for AlphaLISA no-wash assays.
    Price Range : 736.00 USD - 30200.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA Eu-N1 Streptavidin

    DELFIA® Europium-labeled streptavidin, for use in DELFIA time-resolved fluorescence (TRF) assays.
    List Price : 430.00 USD
  • LANCE Ultra ULight™-anti-GST

    Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.
    Price Range : 534.00 USD - 12600.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-human IgG (Fc specific) AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-human IgG antibody. These beads can be used to capture human IgG antibodies. The antibody conjugated to these beads is Fc-specific, and is a mouse polyclonal antibody.
    Price Range : 736.00 USD - 30200.00 USD
  • AlphaPlex Acceptor Bead 545 Antibody

    Anti-HA AlphaPlex 545 (Tb) Acceptor Beads

    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-HA (hemaglutinin) antibody. These beads can be used to capture HA-tagged proteins and peptides.
    Price Range : 736.00 USD - 30300.00 USD
  • ULight anti-c-myc antibody

    ULight labeled anti-c-myc antibody for LANCE® TR-FRET assays.
    Price Range : 486.00 USD - 12300.00 USD
  • FcRn (human) AlphaLISA Binding Kit

    The AlphaLISA human FcRn binding kit is designed for the detection of binding between FcRn and human IgG using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics using a competition assay format.
    Price Range : 2659.00 USD - 13300.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-rabbit IgG (Fc specific) AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-rabbit IgG antibody. These beads can be used to capture rabbit IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
    Price Range : 736.00 USD - 30200.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA® Eu-N1 Anti-HA

    Europium-labeled anti-HA antibody for binding HA-tagged proteins in DELFIA® time-resolved fluorescence (TRF) assays. The anti-HA antibody is a purified IgG2b subclass of mouse monoclonal antibody. It recognizes the epitope sequence (YPYDVPDYA) derived from the human influenza hemagglutinin (HA) protein.
    Price Range : 712.00 USD - 6900.00 USD
  • AlphaLISA Binding

    FCGR3A/CD16a (176Val/V158) AlphaLISA Binding Kit

    This kit is designed for the detection of binding activity between human FCGR3A (176Val) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
    Price Range : 871.00 USD - 13300.00 USD
  • AlphaPlex Acceptor Bead 545 Antibody

    Anti-Mouse IgG AlphaPlex-545 (Tb) Acceptor Beads

    AlphaPlex-545 (Terbium) Acceptor beads conjugated to anti-mouse IgG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 736.00 USD - 30200.00 USD
  • Anti-HRP AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-HRP antibody. These beads can be used to capture HRP-fusion proteins for AlphaLISA no-wash assays.
    Price Range : 715.00 USD - 29300.00 USD
  • AlphaScreen Anti-Species

    AlphaScreen Rabbit IgG Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-rabbit IgG conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
    Price Range : 225.00 USD - 17300.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA Tb-N1 Streptavidin

    Terbium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
    Price Range : 347.00 USD - 2364.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA Sm-N1 Streptavidin

    Samarium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
    Price Range : 347.00 USD - 2367.00 USD
  • PD-1/PD-L2 (human) AlphaLISA Binding Kit

    The AlphaLISA® human PD-1/PD-L2 binding kit is designed for the detection of binding activity between human PD-1 and PD-L2, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2659.00 USD - 13200.00 USD
  • AlphaLISA Binding

    EGF/EGFR AlphaLISA Binding Kit

    The AlphaLISA® EGF/EGFR binding kit is designed for the detection of binding activity between human EGF and EGFR, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 871.00 USD - 12200.00 USD
  • AlphaPlex Acceptor Bead 545 Antibody

    Anti-human IgG AlphaPlex 545 Acceptor Beads

    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-human IgG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 736.00 USD - 30200.00 USD
  • AlphaScreen Anti-Species

    AlphaScreen GST Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-GST conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
    Price Range : 225.00 USD - 17300.00 USD
  • Alpha Donor Bead Antibody Conjugated

    Anti-rat IgG Alpha Donor Beads

    Alpha Donor beads conjugated to anti-rat IgG antibody. This bead can be used to capture rat IgG antibodies for Alpha no-wash protein detection, antibody detection, antibody binding, and other applications.
    Price Range : 643.00 USD - 10900.00 USD
  • AlphaLISA Binding

    TNFα/TNFR2 (human) AlphaLISA Binding Kit

    The AlphaLISA® human TNFα/TNFR2 binding kit is designed for the detection of binding activity between human TNFα and TNFR2, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2659.00 USD - 13700.00 USD
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