PerkinElmer

Protein-Protein Interaction Research Reagents

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OF

The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study large protein interactions is increasingly important.

Notable, our Alpha technology is a highly flexible, homogenous, no-wash assay ideal for the measurement of protein interactions and complexes as large as 200 nm in size. A bead-based proximity assay, Alpha technology offers the possibility to assay many biological targets including enzymes, receptor-ligand interactions, low-affinity interactions, second messenger levels, DNA, RNA, proteins, peptides, sugars and small molecules.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

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1-25 of 105 Products & Services

  • AlphaPlex-545-antibody-bead2
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    Anti-Mouse IgG AlphaPlex-545 (Tb) Acceptor Beads

    AP105TB-C , AP105TB-M , AP105TB-R
    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-mouse IgG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 700.00 USD - 28700.00 USD
  • AlphaPlex Samarium Acceptor Beads
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    Anti-Human IgG AlphaPlex 645 (Sm) Acceptor beads

    AP103SM-C , AP103SM-M , AP103SM-R
    AlphaPlex™-645 (Samarium) Acceptor beads conjugated to anti-human IgG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 700.00 USD - 28700.00 USD
  • Europium-labeled antibody for LANCE assays
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    LANCE Eu-W1024 anti-FLAG

    AD0273 , AD0274 , AD0275
    Eu-W1024 labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.
    Price Range : 437.00 USD - 9800.00 USD
  • PerkinElmer
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    Protein A AlphaPlex™ 545 Acceptor Beads

    AP101TB-C , AP101TB-M , AP101TB-R
    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to Protein A, for use in Alpha no-wash multiplexing assays.
    Price Range : 700.00 USD - 28700.00 USD
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    AlphaScreen Rabbit IgG Detection Kit

    6760607C , 6760607M , 6760607R
    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-rabbit IgG conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
    Price Range : 214.00 USD - 16400.00 USD
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    AlphaScreen DIG (Digoxin/Digoxigenin) Detection Kit

    6760604C , 6760604M , 6760604R
    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-Dig (digoxin) conjugated AlphaScreen Acceptor beads. 
    Price Range : 214.00 USD - 16400.00 USD
  • LANCE Detection Kit
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    EGF-EGFR LANCE Ultra TR-FRET Binding Kit

    TRF1366C , TRF1366M
    This kit is designed for the detection of binding activity between Human EGF and EGFR using a homogeneous LANCE Ultra TR-FRET assay. This assay can facilitate the design and development of therapeutics which competitively inhibit EGF/EGFR interaction.
    Price Range : 840.00 USD - 11200.00 USD
  • AlphaLISA immunoassay kits
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    PD-1/PD-L2 (human) AlphaLISA Binding Kit

    AL3128C , AL3128F
    The AlphaLISA® human PD-1/PD-L2 binding kit is designed for the detection of binding activity between human PD-1 and PD-L2, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2529.00 USD - 12600.00 USD
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    AlphaScreen C-MYC Detection Kit

    6760611C , 6760611M , 6760611R
    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-c-myc-conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
    Price Range : 214.00 USD - 16400.00 USD
  • Quick View

    Anti-DNP AlphaLISA Acceptor Beads

    AL173C , AL173M , AL173R
    AlphaLISA® Acceptor beads conjugated to anti-DNP antibody. These beads can be used to capture DNP-labeled proteins, peptides, and small molecules.
    Price Range : 949.00 USD - 22100.00 USD
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    Anti-HA AlphaLISA Acceptor Beads

    AL170C , AL170M , AL170R
    AlphaLISA Acceptor beads conjugated to anti-HA (hemagglutinin) antibody. These beads can be used to capture HA-tagged proteins and peptides.
    Price Range : 700.00 USD - 28800.00 USD
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    Strep-Tactin® AlphaLISA® Acceptor beads

    AL136C , AL136M , AL136R
    AlphaLISA® Acceptor beads conjugated to Strep-Tactin®. These beads can be used to capture Strep-tag® II-tagged proteins for AlphaLISA no-wash assays.
    Price Range : 680.00 USD - 27900.00 USD
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    Anti-c-myc AlphaLISA® Acceptor Beads

    AL111C , AL111M , AL111R
    AlphaLISA® Acceptor beads conjugated to anti-c-myc antibody. These beads can be used to capture c-myc-tagged proteins and peptides in AlphaLISA no-wash assays.
    Price Range : 700.00 USD - 28700.00 USD
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    Anti-Maltose-Binding Protein (MBP) AlphaLISA® Acceptor beads

    AL134C , AL134M , AL134R
    AlphaLISA® Acceptor beads conjugated to anti-MBP (maltose-binding protein) antibody. The antibody is a rat monoclonal antibody, clone MBP 7G4. These beads can be used to capture MBP-tagged proteins for AlphaLISA no-wash assays.
    Price Range : 700.00 USD - 28700.00 USD
  • Alpha binding assay principle
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    EGF/EGFR AlphaLISA Binding Kit

    AL366HV , AL366C , AL366F
    The AlphaLISA® EGF/EGFR binding kit is designed for the detection of binding activity between human EGF and EGFR, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 828.00 USD - 11600.00 USD
  • Quick View

    LANCE Ultra ULight™-anti-GST

    TRF0104-D , TRF0104-M , TRF0104-R
    Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.
    Price Range : 512.00 USD - 12100.00 USD
  • PerkinElmer
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    SureLight Allophycocyanin-anti-FLAG antibody, 1 mg, lyophilized

    AD0059F
    APC-labeled anti-FLAG antibody, for capturing FLAG-tagged proteins and peptides in LANCE TR-FRET assays.
    List Price : 619.00 USD
  • AlphaLisa Analyte 2
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    EGFR (human), lyophilized (AlphaLISA), 4.78 µg

    AL366S
    EGFR (human), for use in the AlphaLISA EGF/EGFR Binding Assay.
    List Price : 286.00 USD
  • AlphaLISA binding assay principle
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    PD-1/PD-L1 (human) AlphaLISA Binding Kit

    AL356HV , AL356C , AL356F
    The AlphaLISA® human PD-1/PD-L1 binding kit is designed for the detection of binding activity between human PD-1 and PD-L1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 828.00 USD - 11600.00 USD
  • AlphaLISA immunoassay kits
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    FCGR2B/CD32b AlphaLISA Binding Kit

    AL3080C , AL3080F
    This kit is designed for the detection of binding between FCGR2B (CD32b) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
    Price Range : 2529.00 USD - 12600.00 USD
  • Quick View

    Streptavidin AlphaLISA® Acceptor beads

    AL125C , AL125M , AL125R
    AlphaLISA® Acceptor beads conjugated to streptavidin. These beads can be used to capture biotinylated proteins, peptides, nucleic acids (DNA and RNA), and small molecules for AlphaLISA no-wash assays.
    Price Range : 700.00 USD - 28700.00 USD
  • Europium-labeled antibody for LANCE assays
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    LANCE Eu-anti-C-tag antibody

    AD0279 , AD0280 , AD0281
    Europium-labeled anti-C-tag antibodies for LANCE® TR-FRET assays. This mouse monoclonal IgG1 antibody recognizes N-terminal and C-terminal Protein C tagged fusion proteins. The anti-C-tag antibody can be used to capture C-tag proteins, and can be used in conjunction with LANCE ULight or SureLight™ APC-labeled reagents to create LANCE TR-FRET assays.
    Price Range : 346.00 USD - 9800.00 USD
  • AlphaLISA immunoassay kits
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    FcRn (human) AlphaLISA Binding Kit

    AL3095C , AL3095F
    The AlphaLISA human FcRn binding kit is designed for the detection of binding between FcRn and human IgG using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics using a competition assay format.
    Price Range : 2529.00 USD - 12600.00 USD
  • Alpha donor antibody coated
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    Anti-GFP Alpha Donor Beads

    AS112D , AS112M , AS112R
    Alpha Donor beads conjugated to anti-GFP antibody. The antibody is a mouse monoclonal antibody that recognizes wildtype and recombinant GFP (rGFP), and cross-reacts with eGFP. These beads can be used to capture GFP-tagged proteins for AlphaScreen, AlphaLISA, and AlphaPlex no-wash assays.
    Price Range : 729.00 USD - 10600.00 USD
  • Quick View

    ULight anti-c-myc antibody

    TRF504D , TRF504M , TRF504R
    ULight™ labeled anti-c-myc antibody for LANCE® TR-FRET assays.
    Price Range : 465.00 USD - 11800.00 USD
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