PerkinElmer

Protein-Protein Interaction Research Reagents

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The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study large protein interactions is increasingly important.

Notable, our Alpha technology is a highly flexible, homogenous, no-wash assay ideal for the measurement of protein interactions and complexes as large as 200 nm in size. A bead-based proximity assay, Alpha technology offers the possibility to assay many biological targets including enzymes, receptor-ligand interactions, low-affinity interactions, second messenger levels, DNA, RNA, proteins, peptides, sugars and small molecules.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Products & Services (108)
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1-25 of 108 Products & Services

  • AlphaLISA immunoassay kits

    MMP-7 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human MMP7 enables the detection and quantitation of human pro- and active MMP-7 (hMMP-7) in serum, buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 531.00 USD - 11600.00 USD
  • Alphaplex-545-terbium-glutathione

    Glutathione AlphaPlex™ 545 Acceptor Beads

    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to glutathione, for use in Alpha no-wash multiplexing assays.
    Price Range : 700.00 USD - 28700.00 USD
  • Alpha donor antibody coated

    Anti-DNP Alpha Donor Beads

    Alpha Donor beads conjugated to anti-DNP antibody. These beads can be used to capture DNP-labeled proteins, peptides, and small molecules.
    Price Range : 1896.00 USD - 22100.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA® Eu-N1 Anti-c-myc

    Europium-labeled anti-c-myc antibody, for capturing c-myc-tagged proteins in DELFIA® TRF assays.
    Price Range : 730.00 USD - 6600.00 USD
  • AlphaLISA immunoassay kits

    FcγR2A/CD32a (167R) AlphaLISA Binding Kit

    This kit is designed for the detection of binding between FCGR2A (CD32a) (167R) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
    Price Range : 2529.00 USD - 12600.00 USD
  • Europium-labeled antibody for LANCE assays

    Eu-anti-V5 (LANCE TR-FRET)

    Europium-labeled anti-V5 antibody, for capturing V5-tagged proteins in LANCE® TR-FRET assays. This Europium-labeled reagent can be used to capture V5-tagged proteins and peptides, and can be used in conjunction with LANCE® ULight or SureLight APC reagents to create TR-FRET no-wash assays for protein-protein interaction, protein detection, and enzymatic studies.
    Price Range : 336.00 USD - 9500.00 USD
  • AlphaPlex Samarium Acceptor Beads

    Unconjugated AlphaPlex™ 545 Acceptor Beads

    Unconjugated AlphaPlex 645 (Samarium) Acceptor beads bear reactive aldehyde groups at their surface, allowing you to conjugate a wide variety of reagents using a simple reductive amination protocol.
    Price Range : 1599.00 USD - 33700.00 USD
  • Anti-c-myc AlphaLISA® Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-c-myc antibody. These beads can be used to capture c-myc-tagged proteins and peptides in AlphaLISA no-wash assays.
    Price Range : 700.00 USD - 28700.00 USD
  • AlphaPlex-545-antibody-bead2

    Anti-Mouse IgG AlphaPlex-545 (Tb) Acceptor Beads

    AlphaPlex-545 (Terbium) Acceptor beads conjugated to anti-mouse IgG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 700.00 USD - 28700.00 USD
  • Alpha donor antibody coated

    Anti-GFP Alpha Donor Beads

    Alpha Donor beads conjugated to anti-GFP antibody. The antibody is a mouse monoclonal antibody that recognizes wildtype and recombinant GFP (rGFP), and cross-reacts with eGFP. These beads can be used to capture GFP-tagged proteins for AlphaScreen, AlphaLISA, and AlphaPlex no-wash assays.
    Price Range : 729.00 USD - 10600.00 USD
  • AlphaPlex-545-unconjugated

    Unconjugated AlphaPlex-545 Acceptor Beads

    Unconjugated AlphaPlex 545 (Terbium) Acceptor beads bear reactive aldehyde groups at their surface, allowing you to conjugate a wide variety of reagents using a simple reductive amination protocol.
    Price Range : 1599.00 USD - 33700.00 USD
  • LANCE Ultra ULight™-Streptavidin

    Streptavidin labeled with ULight™ dye.
    Price Range : 344.00 USD - 6700.00 USD
  • Assay principle for the AlphaLISA PCSK9/LDLR binding kit

    PCSK9/LDLR (human) AlphaLISA Binding Kit

    This kit is designed to assess binding and inhibition of human PCSK9 and LDLR, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapetics using competition assays.
    Price Range : 2860.00 USD - 20400.00 USD
  • Anti-rat IgG (Fc specific) AlphaLISA® Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-rat IgG antibody. These beads can be used to capture rat IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
    Price Range : 700.00 USD - 28700.00 USD
  • Europium labeled Anti-6xHis antibody for LANCE assays, 50 µg

    LANCE Eu-W1024 Anti-6xHis

    Europium-labeled anti-6X His antibody, for capturing His-tagged proteins in LANCE® TR-FRET assays.
    Price Range : 256.00 USD - 12100.00 USD
  • LANCE Ultra ULight™-anti-GST

    Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.
    Price Range : 512.00 USD - 12100.00 USD
  • FcγR2A/CD32a (167H) AlphaLISA Binding Kit

    This kit is designed for the detection of binding between FCGR2A (CD32a) (167H) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
    Price Range : 2529.00 USD - 12600.00 USD
  • Anti-C-tag AlphaLISA Acceptor Beads

    AlphaLISA Acceptor beads conjugated to anti-C-tag antibody. These beads can be used to capture C-tag proteins, and can be used in conjunction with Alpha Donor beads to create AlphaLISA no-wash assays.
    Price Range : 701.00 USD - 28700.00 USD
  • Alphaplex_545_protein_coated

    Streptavidin AlphaPlex™ 545 Acceptor Beads

    Streptavidin-coated AlphaPlex™ 545 (Terbium) Acceptor beads, for use in Alpha no-wash multiplexing assays.
    Price Range : 700.00 USD - 28700.00 USD
  • AlphaLISA anti-mouse IgG Acceptor beads

    AlphaLISA Acceptor beads conjugated to anti-mouse IgG antibody. This antibody is not Fc-specific; for Fc-specific beads, please see product AL105.
    Price Range : 673.00 USD - 27600.00 USD
  • Europium-labeled antibody for LANCE assays

    LANCE Eu-W1024 anti-FLAG

    Eu-W1024 labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.
    Price Range : 437.00 USD - 9800.00 USD
  • AlphaLISA binding assay principle

    PD-1/PD-L1 (human) AlphaLISA Binding Kit

    The AlphaLISA® human PD-1/PD-L1 binding kit is designed for the detection of binding activity between human PD-1 and PD-L1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 828.00 USD - 11600.00 USD
  • LANCE Detection Kit

    EGF-EGFR LANCE Ultra TR-FRET Binding Kit

    This kit is designed for the detection of binding activity between Human EGF and EGFR using a homogeneous LANCE Ultra TR-FRET assay. This assay can facilitate the design and development of therapeutics which competitively inhibit EGF/EGFR interaction.
    Price Range : 840.00 USD - 11200.00 USD
  • Anti-bovine IgA AlphaLISA Acceptor Beads

    AlphaLISA Acceptor beads conjugated to anti-bovine IgA antibody. These beads can be used to capture bovine IgA antibodies.
    Price Range : 949.00 USD - 32100.00 USD
  • Anti-DIG AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to a mouse monoclonal anti-Dig (digoxin) antibody. These beads can be used to capture Dig-labeled proteins, peptides, and other biomolecules to create AlphaLISA no-wash assays.
    Price Range : 700.00 USD - 28700.00 USD
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