PerkinElmer

Protein-Protein Interaction Research Reagents

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The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study large protein interactions is increasingly important.

Notable, our Alpha technology is a highly flexible, homogenous, no-wash assay ideal for the measurement of protein interactions and complexes as large as 200 nm in size. A bead-based proximity assay, Alpha technology offers the possibility to assay many biological targets including enzymes, receptor-ligand interactions, low-affinity interactions, second messenger levels, DNA, RNA, proteins, peptides, sugars and small molecules.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Products & Services (109)
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1-25 of 109 Products & Services

  • AlphaPlex Samarium Acceptor Beads

    Protein A AlphaPlex™ 645 (Sm) Acceptor Beads

    AlphaPlex-645 (Samarium) Acceptor beads conjugated to Protein A. These beads are used to capture immunoglobulins through their heavy chain (Fc region) allowing optimal orientation and antigen detection. Protein A has higher affinity for rabbit, pig, dog and cat IgG.
    Price Range : 612.00 USD - 25100.00 USD
  • AlphaScreen FITC (Fluorescein) Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-FITC conjugated AlphaScreen Acceptor beads. 
    Price Range : 200.00 USD - 14400.00 USD
  • ULight Anti-C-tag

    ULight™ labeled anti-C-tag antibodies for LANCE® TR-FRET assays. This mouse monoclonal IgG1 antibody recognizes N-terminal and C-terminal Protein C tagged fusion proteins. The anti-C-tag antibody can be used to capture C-tag proteins, and can be used in conjunction with LANCE Europium-labeled reagents to create LANCE TR-FRET assays.
    Price Range : 453.00 USD - 11100.00 USD
  • AlphaPlex-545-antibody-bead2

    Anti-Mouse IgG AlphaPlex-545 (Tb) Acceptor Beads

    AlphaPlex-545 (Terbium) Acceptor beads conjugated to anti-mouse IgG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 612.00 USD - 25100.00 USD
  • Anti-GFP AlphaLISA® Acceptor beads

    AlphaLISA® Acceptor beads conjugated to anti-GFP antibody. The antibody is a mouse monoclonal antibody that recognizes wildtype and recombinant GFP (rGFP), and cross-reacts with eGFP. These beads can be used to capture GFP-tagged proteins for AlphaLISA no-wash assays.
    Price Range : 613.00 USD - 25200.00 USD
  • Anti-C-tag AlphaLISA Acceptor Beads

    AlphaLISA Acceptor beads conjugated to anti-C-tag antibody. These beads can be used to capture C-tag proteins, and can be used in conjunction with Alpha Donor beads to create AlphaLISA no-wash assays.
    Price Range : 613.00 USD - 25100.00 USD
  • Anti-rabbit IgG (Fc specific) AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-rabbit IgG antibody. These beads can be used to capture rabbit IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
    Price Range : 613.00 USD - 25200.00 USD
  • Nickel Chelate AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to nickel chelate. These beads can be used to capture His-tagged proteins and peptides.
    Price Range : 613.00 USD - 25200.00 USD
  • AlphaLISA immunoassay kits

    PD-1/PD-L1 (human) AlphaLISA Binding Kit

    The AlphaLISA® human PD-1/PD-L1 binding kit is designed for the detection of binding activity between human PD-1 and PD-L1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 725.00 USD - 10200.00 USD
  • Streptavidin AlphaLISA® Acceptor beads

    AlphaLISA® Acceptor beads conjugated to streptavidin. These beads can be used to capture biotinylated proteins, peptides, nucleic acids (DNA and RNA), and small molecules for AlphaLISA no-wash assays.
    Price Range : 613.00 USD - 25200.00 USD
  • Protein A AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to Protein A. These beads can be used to capture antibodies that associate with Protein A.
    Price Range : 613.00 USD - 25200.00 USD
  • AlphaScreen Mouse IgG Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-mouse IgG conjugated AlphaScreen Acceptor beads.
    Price Range : 188.00 USD - 14400.00 USD
  • ULight anti-FITC

    ULight™ labeled anti-FITC antibody for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.
    Price Range : 446.00 USD - 11300.00 USD
  • AlphaLisa Analyte 2

    EGFR (human), lyophilized (AlphaLISA), 4.78 µg

    EGFR (human), for use in the AlphaLISA EGF/EGFR Binding Assay.
    List Price : 250.00 USD
  • Alpha donor antibody coated

    Anti-DNP Alpha Donor Beads

    Alpha Donor beads conjugated to anti-DNP antibody. These beads can be used to capture DNP-labeled proteins, peptides, and small molecules.
    Price Range : 1659.00 USD - 19400.00 USD
  • AlphaPlex Samarium Acceptor Beads

    Streptavidin AlphaPlex™ 645 (Sm) Acceptor Beads

    The Streptavidin coated AlphaPlex™ 645 (Samarium) Acceptor beads are used to capture a wide variety of biotinylated reagents, ranging from small nucleotides to very large proteins. To avoid steric hindrance, it is recommended to use biotin derivatives including an aliphatic spacer composed of at least six carbons.
    Price Range : 612.00 USD - 25100.00 USD
  • ULight anti-c-myc antibody

    ULight labeled anti-c-myc antibody for LANCE® TR-FRET assays.
    Price Range : 446.00 USD - 11300.00 USD
  • Alpha donor antibody coated

    Anti-rat IgG Alpha Donor Beads

    Alpha Donor beads conjugated to anti-rat IgG antibody. This bead can be used to capture rat IgG antibodies for Alpha no-wash protein detection, antibody detection, antibody binding, and other applications.
    Price Range : 535.00 USD - 9100.00 USD
  • Assay principle for AlphaLISA TNFa/TNFR1 binding kit

    TNFα/TNFR1 (human) AlphaLISA Binding Kit

    The AlphaLISA® human TNFα/TNFR1 binding kit is designed for the detection of binding activity between human TNFα and TNFR1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2213.00 USD - 11400.00 USD
  • AlphaPlex-545-antibody-bead2

    Anti-rabbit IgG AlphaPlex-545 (Tb) Acceptor Beads

    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-rabbit IgG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 612.00 USD - 25100.00 USD
  • Assay principle for AlphaLISA TNFa/TNFR2 binding kit

    TNFα/TNFR2 (human) AlphaLISA Binding Kit

    The AlphaLISA® human TNFα/TNFR2 binding kit is designed for the detection of binding activity between human TNFα and TNFR2, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2213.00 USD - 11400.00 USD
  • Anti-DIG AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to a mouse monoclonal anti-Dig (digoxin) antibody. These beads can be used to capture Dig-labeled proteins, peptides, and other biomolecules to create AlphaLISA no-wash assays.
    Price Range : 613.00 USD - 25200.00 USD
  • AlphaScreen C-MYC Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-c-myc-conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
    Price Range : 188.00 USD - 14400.00 USD
  • Protein G AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to Protein G. These beads can be used to capture antibodies that associate with Protein G.
    Price Range : 613.00 USD - 25200.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA Sm-N1 Streptavidin

    Samarium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
    Price Range : 320.00 USD - 2180.00 USD
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