Protein Kinase Research Reagents

Cancer, diabetes, and Alzheimer’s research can benefit from the study of phosphorylation and protein kinase activity. Because of their role in signal transduction, kinase activity detection and characterization is significant for drug discovery.

We offer a range of end-point and real-time kinetic protein kinase assays, technologies, and instruments that allow rapid kinase detection, screening, and mechanism-of-action studies.

Our offerings include:

• Labeled substrates for kinetic assays and antibody-free screening
• AlphaLISA^® kits for highly-sensitive detection of cellular phosphorylation
• LANCE^® TR-FRET protein kinase assays for rapid assay selection
• Fast and simple assays using pre-validated peptide and protein substrates derived from biologically-relevant targets

Regulation and inhibition of kinase activity can open new pathways for therapeutics, especially in conditions related to cell signaling and growth factors. Whether you work with serine/threonine-specific, tyrosine-specific, histidine-specific, or mixed kinases, our kinase activity assays and technologies enable rapid assay selection and accelerate drug development.