PerkinElmer

Protein Kinase Research Reagents

› ‹
OF

Cancer, diabetes, and Alzheimer’s research can benefit from the study of phosphorylation and protein kinase activity. Because of their role in signal transduction, kinase activity detection and characterization is significant for drug discovery.

We offer a range of end-point and real-time kinetic protein kinase assays, technologies, and instruments that allow rapid kinase detection, screening, and mechanism-of-action studies.

Our offerings include:

  • Labeled substrates for kinetic assays and antibody-free screening
  • AlphaLISA® kits for highly-sensitive detection of cellular phosphorylation
  • LANCE® TR-FRET protein kinase assays for rapid assay selection
  • Fast and simple assays using pre-validated peptide and protein substrates derived from biologically-relevant targets

Regulation and inhibition of kinase activity can open new pathways for therapeutics, especially in conditions related to cell signaling and growth factors. Whether you work with serine/threonine-specific, tyrosine-specific, histidine-specific, or mixed kinases, our kinase activity assays and technologies enable rapid assay selection and accelerate drug development.

Products & Services (251)
Filters:

FILTER BY

Expand All Collapse All
Assay Target
  • 4E-BP1 (1)
  • 4EBP1 (3)
  • Acetyl CoA carboxylase (2)
  • Akt1 (3)
  • Akt1/2/3 (6)
  • ALK (1)
  • AMPKα1/2 (1)
  • AMPKα (2)
  • AMPKα1/2 (1)
  • ATF2 (1)
  • BAD (2)
  • BTK (2)
  • c-Jun (1)
  • c-Met (1)
  • c-Myc (3)
  • CDK2 (1)
  • CDK4 (1)
  • Chk-2 (1)
  • CHK1 (1)
  • Cofilin (4)
  • CREB (2)
  • EGFR (5)
  • eIF2α (4)
  • eiF4E (1)
  • eIF4E (2)
  • ErbB2 (1)
  • ERK1/2 (6)
  • FGF Receptor 1 (1)
  • FGF Receptor 2 (2)
  • FGF Receptor 3 (2)
  • FGF Receptor 4 (1)
  • GAPDH (1)
  • GSK3α (1)
  • GSK3β (1)
  • Histone H3 (1)
  • Hsp27 (1)
  • IGF-1 Rec. β (2)
  • IGFR (2)
  • IKKα (2)
  • IKKβ (1)
  • INSR (1)
  • Insulin Rec. β (2)
  • IκBα (1)
  • JAK2 (1)
  • JNK1/2 (1)
  • JNK1/2/3 (2)
  • KAP1 (2)
  • LCK (1)
  • MEK1 (2)
  • MKK3/6 (1)
  • MKK4 (2)
  • mTOR (1)
  • NFκB (5)
  • p-ALK (Tyr1586) (1)
  • p-ALK (Tyr1604) (1)
  • p-CHK1 (Ser345) (1)
  • p-Insulin Rec. β (Tyr1150/1151) (1)
  • p-PDGF Receptor β (Tyr751) (1)
  • p38 MAPK (3)
  • p53 (1)
  • p70 S6K (4)
  • PDGF Receptor &beta (1)
  • PDGF Receptor β (1)
  • PDK1 (1)
  • Raf-1 (2)
  • Ras (1)
  • Rb (4)
  • S6RP (3)
  • SHP-1 (2)
  • SHP-2 (1)
  • SLP-76 (5)
  • SMAD1 (4)
  • SMAD2 (4)
  • SMAD3 (4)
  • Src (2)
  • STAT1 (7)
  • STAT3 (5)
  • STAT4 (2)
  • STAT5 (3)
  • STAT6 (3)
  • STING (1)
  • SYK (4)
  • TBK1 (3)
  • TREM2 (1)
  • TrkA (1)
  • TrkB (1)
  • VEGF2 Receptor (3)
  • VEGFR2 (2)
  • Zap70 (4)
  • β-Catenin (1)
Target Species
  • Human (3)
  • Mouse (1)
Application
  • Enzymatic (1)
  • Kinase (165)
  • Mobility Shift (1)
  • Molecular Biology (10)
  • Multiplexing (31)
  • Protein Analysis & Detection (168)
Therapeutic Area
  • Auto-Immunity (3)
  • CNS (1)
  • Immuno-oncology (3)
  • Inflammation (3)
  • Metabolism (3)
  • NASH (1)
  • Oncology (23)
Product Brand Name
  • Alpha SureFire Ultra Multiplex (35)
  • AlphaLISA SureFire Ultra (84)
  • AlphaPlex (1)
  • AlphaScreen (4)
  • AlphaScreen SureFire (17)
  • DELFIA (5)
  • easylite-Kinase (1)
  • EasyTide (3)
  • LANCE (4)
  • LANCE Ultra (29)
  • LANCE SureLight (1)
  • LANCE Ultra (36)
  • NEN (2)
  • NEN Radiochemicals (5)
Detection Method
  • Alpha (157)
  • DELFIA TRF (5)
  • Luminescence (1)
  • Radiometric (10)
  • Time-Resolved Fluorescence (TRF) (77)
  • TR-FRET (72)
Molecular Modification
  • Phosphorylation (67)
Sample Type
  • Enzyme (1)
Antibody Conjugates
  • Anti-P-Ser 14-3-3 (1)
  • Anti-P-Tyr-100 (1)
  • Anti-phospho-4EBP1 (1)
  • Anti-phospho-Acetyl-CoA-Carboxylase (1)
  • Anti-phospho-Crosstide (1)
  • Anti-phospho-glycogen synthase (1)
  • Anti-phospho-Histone H3 (2)
  • Anti-phospho-I?Ba (1)
  • Anti-phospho-MEK1/2 (1)
  • Anti-phospho-p70S6K (1)
  • Anti-phospho-PKC (1)
  • Anti-phospho-PLK (1)
  • Anti-phospho-rpS6 (1)
  • Anti-phospho-serine (1)
  • Anti-phospho-threonine (1)
  • Anti-phospho-Topo IIa (1)
  • Anti-phospho-Tyrosine Hydroxylase (1)
  • P-Tyr-100 (1)
  • PT66 (2)
  • PY20 (2)
  • Streptavidin (1)
  • Streptavidin/P-Tyr-100 (1)
  • Streptavidin/Phosphosensor (1)
  • Streptavidin/PT66 (1)
  • Streptavidin/PY20 (1)
Radioisotope
  • P-32 (8)
  • S-35 (2)
Radionuclide
  • 32P (8)
  • 35S (2)
Nucleotide
  • ATP (7)
  • GTP (3)
Fluorophore
  • Eu-N1 (5)
  • Eu-W1024 (22)
  • SureLight-APC (1)
  • ULight (18)
Label Position
  • gamma (10)
Assay Points (200-50,000)
  • 100 (129)
  • 1000 (1)
  • 10000 (176)
  • 500 (172)
  • 5000 (4)
  • 50000 (150)
Assay Target Class
  • Kinase (1)
  • Phospho-protein (4)
  • Phosphoprotein (120)
  • Protein (70)
Automation Compatible
  • Yes (232)
Concentration
  • 10 mCi/mL (5)
  • 12.5 mCi/mL (1)
  • 2 mCi/mL (1)
  • 5 mCi/mL (2)
Experimental Type
  • In vitro (109)
Format
  • Microplates (85)

Sort by

1-25 of 251 Products & Services

  • Jump to:
Technical Resources (344)
Tools & More(13)
Business Insights (1)
Filters:

Sort by

1-1 of 1 Business Insights