Protein Aggregation

Protein aggregates and resulting toxic inclusions are considered hallmarks of many neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and ALS. The investigation into proteionopathies that wreak havoc on the normal functioning of the brain is an active field within both basic and drug discovery research.

PerkinElmer offers a range of reagents, consumables, instruments, and corresponding software to accelerate your neuroscience research with end-to-end high-throughput screening and high-content imaging solutions. We offer reliable high-throughput immunoassays employing HTRF® and AlphaLISA® technology that are cost-effective alternatives to traditional ELISAs. These can be used to look at important protein aggregate markers such as tau, amyloid β, NFL, and TDP-43 on the VICTOR® Nivo or EnVision® multimode plate readers, as well as the Opera Phenix® Plus High Content Screening System with its accompanying Harmony® software and Columbus system, imaging dyes, and microplates for both 2D and 3D complex neurological disease modeling and drug discovery insights.

Featured Solutions and Products

Microplate Readers

Performance, Versatility, and Reliability for Today’s Laboratory Needs As many of you know, microplate readers are instruments used to detect biological, chemic ...

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Since their introduction in the 1950’s immunoassays have been an integral part of research and drug discovery labs. Immunoassay platforms are commonly used to d ...

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Opera Phenix Plus High-Content Screening System

The Opera Phenix® Plus High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a de ...

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Aβ 1-40 (human) High Specificity AlphaLISA Detection Kit, 500 Assay Points

The AlphaLISA® immunoassay kit for human Aβ40 enables the detection and quantitation of human Aβ40 in human cerebrospinal fluid and cell culture supernatants us ...

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TAU (human) AlphaLISA Detection Kit, 500 Assay Points

The AlphaLISA® Human Microtubule-associated Protein Tau (TAU) Detection Kit is designed for detection and quantitation of human TAU in cerebrospinal fluid (CSF) ...

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