Noninvasive Prenatal Testing

Noninvasive prenatal testing (NIPT) consists of analyzing cell-free DNA (cfDNA) circulating in the maternal blood in order to detect Down's syndrome and other fetal chromosomal abnormalities. From a simple blood test, NIPT has demonstrated its superior efficacy to detect trisomies thereby reducing the number of further invasive testing procedures.

By enabling early access to reliable results, NIPT has quickly been integrated in various screening programs across the world. However, cell-free DNA testing for aneuploidy screening has been so far limited by the complexity, cost and capacity of existing NIPT technologies.

Vanadis® NIPT System is an automated solution designed to solve these challenges and allow laboratories to screen more women with NIPT.

Products may not be licensed in accordance with the laws in all countries, such as the United States and Canada. Please check with your local representative for availability.


Based on a breakthrough in advanced genetic analytics, Vanadis® NIPT system is the only NIPT screening platform to enable targeted cfDNA analysis without next-generation sequencing or PCR, instead directly capturing target fragments and labeling them for counting. A proprietary nanofilter plate then captures labeled molecules for imaging, eliminating the need for data-intensive steps such as DNA sequencing, microarrays, and microfluidics.

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Clinical Performance

The Vanadis® NIPT system is used for the screening for the risk of trisomy 21, 18, and/or 13.

It is a high-precision NIPT platform designed to improve the access to NIPT to more women and reduce the no-call rate in order to improve the overall performance of the screening program.

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With Vanadis® NIPT system technology, all the critical steps are automated, starting with pipetting steps to reduce manual errors. Plasma volumes are monitored by camera to avoid contamination by the buffy coat, and samples and reagents are barcoded for complete tracking throughout the workflow. A system software guides you through the process, with user-friendly touchscreens, and enables remote workflow management for ease of use.

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Vanadis® NIPT system includes system software and trusted LifeCycle software, the complete data management solution for prenatal screening laboratories. With a simple and flexible user interface and a performance monitoring dashboard that enables access from any current web browser, the software provide the reliability and support laboratories need.

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Featured Content

Vanadis NIPT System Brochure

With our high-throughput Vanadis NIPT solution, we’re taking much of the complexity out of cell-free DNA (cfDNA) testing, making it accessible to more women – a ...

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High-Precision Prenatal Aneuploidy Screening with Automated Quality Assessment

This white paper describes the built-in quality assessment procedures of Vanadis NIPT, and how the system is designed to ensure clinical accuracy, and the highe ...

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Vanadis NIPT: An Automated System for High-Precision Prenatal Screening

This whitepaper describes the importance of assay precision in achieving high detection rate of fetal aneuploidies. Furthermore, the paper shows how the Vanadis ...

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