Proteins differ from each other in their size, molecular structure and physiochemical properties. These differences allow for protein analysis and characterization by separation and identification. The LabChip® GXII Touch™ protein characterization system offers rapid peak quantification and quality control throughout the protein purification workflow.
The platform supports multiple assays for characterizing proteins in reduced and non-reduced samples including:
Analyze critical quality attributes in as few as 42 seconds:
Titer (concentration and sizing)
Aggregation (covalently linked)
Stability (degradation / fragmentation analysis)
mAb Charge variant / charge heterogeneity
mAb impurity analysis (detect minor impurities)
Analysis can be performed in as few as forty seconds per sample that deliver comparable data to traditional capillary electrophoresis with as much as a 70X increase in throughput. Choose 96-well or up to 384-well platforms depending upon throughput needs. With an easy to use touch screen interface, even occasional users get up and running samples quickly.
Throughout the workflow, total sample protein quantitation is required. The DropletQuant® UV-VIS spectrophotometer provides full-spectral quantitation scans of 96 samples in fewer than 5 minutes. With a wide dynamic range, sample throughput flexibility, and input volumes of 2 µL, the DropletQuant® system enables a faster time-to-result.
For research use only. Not for use in diagnostic procedures.
The LabChip® GXII Touch™ protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Leveraging microfluidic electrophoretic separation technology, the LabChip® GXII Touch™ system enables rapid characterization with minimal sample preparation setup and sample input volume.
"Microfluidic Protein Characterization Analysis"1-2
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