PerkinElmer

Metabolic Disease

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Metabolic diseases like diabetes are increasingly widespread, and research for this class of diseases relies on discovering and quantifying biomarkers to elucidate underlying mechanisms and uncover novel drug targets. Our portfolio of metabolic assays are well suited for metabolic disease research in vitro, in vivo, and in situ, and offer novel tools for your research workflow from start to finish.

Metabolic diseases are systemic and manifest with a variety of biological changes, from autophagy dysfunction to altered blood coagulation. For easy detection of a wide range of metabolic biomarkers, we offer fast and pre-validated metabolic assay reagents, kits, and imaging systems. For targeted binding studies, we also provide target-specific radiolabeled reagents.

Our products for metabolic disease research include:

  • LANCE® TR-FRET technology
  • AlphaLISA® immunoassay kits
  • Alpha reagents for AlphaLISA
  • DELFIA® TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Target-specific radiolabeled ligands, carbohydrates, lipids, and steroids

The range of tools offered allows for the detection and quantitation of many key biomolecules in metabolic disease research. Gain precise insight on disease biomarkers like c-reactive protein, fibrinogen, IGF, FGF, insulin and glucagon, leptin and ghrelin, adiponectin, and factor VIII.

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Product Type
  • Instruments (1)
  • Reagents (140)
  • Software and Informatics (4)
Assay Target
  • Adiponectin (3)
  • Albumin (5)
  • ApoA1 (4)
  • ApoB (2)
  • ApoC3 (2)
  • ApoE (2)
  • AST (1)
  • BMP-9 (1)
  • C-peptide (2)
  • CCL2 (1)
  • Corticosterone (2)
  • Cortisol (3)
  • Factor VIII (1)
  • FSH (3)
  • Ghrelin (4)
  • GLP-1 (2)
  • Glucagon (3)
  • Growth Hormone (1)
  • hCG (3)
  • HO-1 (1)
  • HO-2 (1)
  • IGF1 (5)
  • IGF2 (1)
  • Insulin (4)
  • KIM-1 (1)
  • LDH (1)
  • Leptin (5)
  • MANF (2)
  • MBNL1 (1)
  • NNMT (1)
  • Osteoprotegerin (1)
  • PCSK9 (1)
  • PIGF (1)
  • PON1 (1)
  • PON2 (1)
  • Progesterone (1)
  • PSMA (2)
  • SHP2 (1)
  • Somatostatin (1)
  • Testosterone (1)
  • TSH (4)
  • Utrophin (1)
Target Species
  • Human (76)
  • Mouse (5)
  • Rat (4)
Application
  • Protein Analysis & Detection (82)
Therapeutic Area
  • Angiogenesis (1)
  • Biologics/Bioprocess (4)
  • Cancer (4)
  • Central Nervous System (1)
  • Inflammation (4)
  • Metabolic (62)
Product Brand Name
  • AlphaLISA (53)
  • AlphaPlex (2)
  • LANCE Ultra (28)
  • Membrane Target Systems (1)
  • NEN Radiochemicals (54)
  • Quantum (1)
Detection Method
  • Alpha (55)
  • Radiometric (55)
  • Time-Resolved Fluorescence (TRF) (25)
  • TR-FRET (25)
Receptor Type
  • Ghrelin (1)
Assay Validated
  • Binding (1)
Radioisotope
  • C-14 (27)
  • H-3 (28)
Radionuclide
  • 14C (27)
  • 3H (28)
Label Position
  • Generally Labeled (2)
  • Nominally Labeled (17)
  • Specifically Labeled (25)
  • Uniformly Labeled (11)
Buffer
  • Aqueous (10)
  • Aqueous PT6-271 Stabilizer (2)
  • Ethanol : water (10)
Assay points(200-50,000)
  • 100 (28)
  • 10000 (16)
  • 500 (55)
  • 5000 (40)
Assay Target Class
  • Cytokine (1)
  • GPCR (1)
  • Hormone (37)
  • Peptide (5)
  • Protein (42)
Automation Compatible
  • Yes (84)
Concentration
  • 0.02 mCi/mL (1)
  • 0.05 mCi/mL (1)
  • 0.1 mCi/mL (11)
  • 0.2 mCi/mL (4)
  • 1 mCi/mL (17)
Experimental Type
  • In vitro (70)
Format
  • Microplates (67)
Host Cell
  • CHO-K1 (1)
Imaging Modality
  • microCT Imaging (1)
Length
  • 901-1000 (1)
Volume
  • 0-50 (15)
  • 201-250 (4)

"Metabolic Disease" 1-50 of 145 Products & Services

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Quantum GX2 microCT imaging system

Quantum GX2 microCT Imaging System

Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
AlphaLISA assay principle

MANF (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human MANF enables the quantitative determination of mesencephalic astrocyte-derived neurotrophic factor (MANF) in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 644.00 USD - 19300.00 USD
Adenosine 5 Triphosphate 250 µCi

Glucose, D-[3-3H]-, in Ethanol/Water

D-glucose, labeled with tritium at C3. This product is supplied in 90% ethanol. Specifically-labeled glucose can be used for metabolic studies and glucose uptake.
Price Range : 788.00 USD - 3651.00 USD
AlphaLISA immunoassay kits

Utrophin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human utrophin enables the quantitative determination of utrophin in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 301.00 USD - 18800.00 USD
AlphaLISA assay principle

TSH (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human TSH enables the quantitative determination of human thyroid stimulating hormone (TSH) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 644.00 USD - 19300.00 USD

Growth Hormone (human) AlphaLISA Detection Kit

The AlphaLISA® Human Growth Hormone Detection Kit is designed for detection and quantitation of human growth hormone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1693.00 USD - 10500.00 USD
PerkinElmer

Uridine diphospho-D-glucose, [6-3H]-, 250 µCi

250 µCi quantities of [6-3H]-Uridine Diphospho-D-Glucose are available for your research.
List Price : 2182.00 USD
AlphaLISA immunoassay kits

Leptin (human) AlphaLISA Detection Kit

The AlphaLISA® Human Leptin Detection Kit is designed for detection and quantitation of human leptin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. Due to the presence of leptin binding proteins in serum or other matrices, an acid-dissociation step might be required before performing the AlphaLISA assay.
Price Range : 1585.00 USD - 10500.00 USD
AlphaLISA immunoassay kits

KIM-1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human Kidney Injury Molecule 1 (KIM-1) enables the quantitative determination of human KIM-1 in buffered solution, urine, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD
Diclofenac sodium- Phenylacetic acid C14

Sucrose, [14C(U)]-Specific Activity: 400-700mCi (14.8-25.9GBq)/mmol, 250µCi (9.25MBq)

250 µCi quantities of [14C(U)]-Sucrose are available for your research.
List Price : 1344.00 USD
LANCE Detection Kit

Adiponectin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Adiponectin Detection Kit is designed for detection and quantitation of human adiponectin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11100.00 USD
AlphaLISA assay principle

BMP-9 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human BMP-9 enables the quantitative determination of human Bone Morphogenetic Protein 9 (BMP-9) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 18800.00 USD
Adenosine 5 Triphosphate 250 µCi

Inositol, Myo,-[2-3H(N)]-, Aqueous/Steri-packaged

Myo-inositol, labeled with tritium. This product is supplied steri-packaged in an aqueous solution. Tritiated myoinositol is commonly used to label lipids.
Price Range : 1928.00 USD - 4837.00 USD
AlphaLISA immunoassay kits

Insulin-like Growth Factor 2 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Insulin-like Growth Factor 2 (IGF2) Detection Kit is designed for detection and quantitation of human IGF2 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1585.00 USD - 10500.00 USD
Adenosine 5 Triphosphate 250 µCi

Myo-inositol, [3H], 1 mCi

Myo-inositol, [3H]- will have fresh lot dates on the second Monday in March and September.
List Price : 3261.00 USD
AlphaLISA immunoassay kits

ApoA1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for ApoA1 is designed for the quantitative determination of ApoA1 in human serum, human plasma and cell supernantants using a homogeneous AlphaLISA assay (no wash steps). Neglible cross reactivity was observed with ApoCIII, ApoE, or ApoB.
Price Range : 644.00 USD - 19300.00 USD
AlphaLISA immunoassay kits

Factor VIII (human) AlphaLISA Detection Kit

The AlphaLISA® Human Factor VIII Detection Kit is designed for detection and quantitation of Human Factor VIII in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 672.00 USD - 10500.00 USD

NNMT (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human Nicotinamide N-Methyltransferase (NNMT) enables the quantitative determination of human NNMT in buffered solution, cell culture media, and serum using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD
Diclofenac sodium- Phenylacetic acid C14

Glucose, D-[1-14C]-, 250µCi (9.25MBq)

250 µCi quantities of D-[14C(U)]-Glucose are available for your research.
List Price : 2372.00 USD

Albumin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Albumin Detection Kit is designed for detection and quantitation of human albumin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 829.00 USD - 11100.00 USD
AlphaLISA immunoassay kits

Albumin (human) AlphaLISA Detection Kit

AlphaLISA no-wash immunoassay kit for detection of human serum albumin (HSA) in urine, buffered solution, or cell culture medium.
Price Range : 3036.00 USD - 23700.00 USD

Leptin (mouse) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse Leptin Detection Kit is designed for detection and quantitation of mouse leptin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11100.00 USD

Somatostatin (human) AlphaLISA Detection Kit

The AlphaLISA® Somatostatin Detection Kit is designed for detection and quantitation of somatostatin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 725.00 USD - 10500.00 USD
AlphaLISA immunoassay kits

Insulin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human insulin enables the detection and quantitation of insulin in serum, buffered solution or cell culture medium using a homogeneous AlphaLISA assay (no wash steps). The antibodies in the kit are mouse monoclonal antibodies (clone numbers 8E2 and 3A6).
Price Range : 1585.00 USD - 10500.00 USD
Diclofenac sodium- Phenylacetic acid C14

Glucose, D-[14C(U)]-

5 mCi quantities of D-[14C(U)]-Glucose are available for your research.
List Price : 7300.00 USD

Chorionic gonadotropin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Chorionic Gonadotropin (hCG) Detection Kit is designed for detection and quantitation of hCG in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 806.00 USD - 10700.00 USD
AlphaLISA immunoassay kits

Testosterone AlphaLISA Detection Kit

The AlphaLISA® Testosterone Research Kit is designed for detection and quantitation of testosterone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 672.00 USD - 10500.00 USD
Adenosine 5 Triphosphate 250 µCi

Glucose, D-[6-3H(N)]

D-glucose, labeled with tritium at C6. This product is supplied in 90% ethanol. D-glucose can be used for metabolic studies and glucose uptake.
Price Range : 668.00 USD - 2442.00 USD
AlphaLisa Analyte 2

IGF-1 (rat), lyophilized (AlphaLISA)

Rat IGF-1 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA Rat IGF-1 Detection Kit, but can also be ordered separately.
List Price : 308.00 USD
Protein

Albumin (human), lyophilized (LANCE)

Human albumin standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human Albumin TR-FRET Detection Kit, but can be ordered separately.
List Price : 250.00 USD
AlphaLISA assay principle

Total Ghrelin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human total ghrelin enables the quantitative determination of total ghrelin in serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 18800.00 USD

Heme oxygenase 2 AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human heme oxygenase 2 (HO-2) enables the quantitative determination of human HO-2 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 451.00 USD - 9900.00 USD
AlphaPlex Samarium immunoassay kits

AlphaPlex-645 (Sm) Human Insulin Detection Kit

The AlphaPlex™ 645 (Samarium) Human Insulin Detection Kit is designed for the quantitative determination of human insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.
Price Range : 480.00 USD - 10500.00 USD

PON-1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human paraoxonase/arylesterase 1 (PON-1) enables the quantitative determination of human PON-1 in buffered solution, serum, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD
Adenosine 5 Triphosphate 250 µCi
List Price : 4173.00 USD
LANCE Detection Kit

TSH (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human TSH Detection Kit is designed for detection and quantitation of human thyroid stimulating hormone in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11100.00 USD
AlphaLISA immunoassay kits

Glucagon (human) AlphaLISA Detection Kit

The AlphaLISA® Glucagon Detection Kit is designed for detection and quantitation of glucagon in cell culture media, sera and plasma, in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 725.00 USD - 10100.00 USD
LANCE Detection Kit

Glucagon (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Glucagon Detection Kit is designed for detection and quantitation of human glucagon in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 829.00 USD - 11100.00 USD

Sucrose, [14C(U)]-, Specific Activity: 400-700mCi (14.8-25.9GBq)/mmol, 50µCi (1.85MBq)

50 µCi quantities of [14C(U)]-Sucrose are available for your research.
List Price : 553.00 USD
Adenosine 5 Triphosphate 250 µCi

Deoxy-D-glucose, 2-[1,2-3H(N)]

250 µCi quantities of Deoxy D Glucose (25-50 Ci/mmol) are available for your research.
List Price : 792.00 USD
AlphaLISA immunoassay kits

SHP-2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human SHP-2 enables the quantitative determination of human Src-homology domain-2 containing protein tyrosine phosphatase 2 (SHP-2) in buffered solution, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD
PerkinElmer

Leptin (mouse), lyophilized (LANCE)

Mouse leptin standard, lyophilized, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Mouse Leptin Detection Kit, but can be ordered separately.
List Price : 250.00 USD
Adenosine 5 Triphosphate 250 µCi

Mannitol, D-[1-3H(N)]

D-mannitol, labeled with tritium at C1. Tritiated manitol is commonly used as an extracellular space marker.
Price Range : 591.00 USD - 1056.00 USD
AlphaLISA immunoassay kits

hCG (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human chorionic gonadotropin (hCG) enables the quantitative determination of hCG in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 541.00 USD - 16200.00 USD
Adenosine 5 Triphosphate 250 µCi

Inulin, Methoxy-, [Methoxy-3H]

Methoxy-inulin, labeled on methoxy groups with tritium. 3H-methoxyinulin is commonly used to measure glomerular fitration rates (GFR) or as an extracellular space marker.
Price Range : 735.00 USD - 2318.00 USD
LANCE Detection Kit

ApoA1 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human ApoA1 Detection Kit is designed for detection and quantitation of human Apolipoprotein A1 (ApoA1) in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 806.00 USD - 10700.00 USD
AlphaLISA immunoassay kits

ApoB (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human ApoB enables the quantitative determination of human apolipoprotein B in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 18800.00 USD
AlphaLISA immunoassay kits

AST (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human AST enables the quantitative determination of human aspartate transaminase (AST) in buffered solution, cell culture media, and serum using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD

Heme oxygenase 1 AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human heme oxygenase 1 (HO-1) enables the quantitative determination of human HO-1 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 451.00 USD - 9900.00 USD

Osteoprotegerin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for total osteoprotegerin enables the quantitative determination of human osteoprotegerin in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 644.00 USD - 19300.00 USD

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