Metabolic Disease

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Metabolic diseases like diabetes are increasingly widespread, and research for this class of diseases relies on discovering and quantifying biomarkers to elucidate underlying mechanisms and uncover novel drug targets. Our portfolio of metabolic assays are well suited for metabolic disease research in vitro, in vivo, and in situ, and offer novel tools for your research workflow from start to finish.

Metabolic diseases are systemic and manifest with a variety of biological changes, from autophagy dysfunction to altered blood coagulation. For easy detection of a wide range of metabolic biomarkers, we offer fast and pre-validated metabolic assay reagents, kits, and imaging systems. For targeted binding studies, we also provide target-specific radiolabeled reagents.

Our products for metabolic disease research include:

LANCE^® TR-FRET technology
AlphaLISA^® immunoassay kits
Alpha reagents for AlphaLISA
DELFIA^® TRF technology
Cellular, tissue, and in vivo imaging systems
Target-specific radiolabeled ligands, carbohydrates, lipids, and steroids

The range of tools offered allows for the detection and quantitation of many key biomolecules in metabolic disease research. Gain precise insight on disease biomarkers like c-reactive protein, fibrinogen, IGF, FGF, insulin and glucagon, leptin and ghrelin, adiponectin, and factor VIII.

Products & Services (135)
Technical Resources (165)
Tools & More (13)
Business Insights (3)

Products & Services (135)

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Product Type

Instruments (1)
Reagents (130)
Software and Informatics (4)

Assay Target

Adiponectin (3)
Albumin (5)
ApoA1 (4)
ApoB (2)
ApoC3 (2)
ApoE (2)
AST (1)
BMP-9 (1)
C-peptide (2)
CCL2 (1)
Corticosterone (2)
Cortisol (3)
CYCS (1)
Factor VIII (1)
FSH (3)
Ghrelin (4)
GLP-1 (2)
Glucagon (3)
Growth Hormone (1)
hCG (3)
HO-1 (1)
HO-2 (1)
IGF1 (5)
IGF2 (1)
Insulin (4)
KIM-1 (1)
LDH (1)
Leptin (5)
MANF (2)
MBNL1 (1)
NNMT (1)
Osteoprotegerin (2)
PCSK9 (1)
PIGF (1)
PON1 (1)
PON2 (1)
Progesterone (1)
PSMA (2)
SHP2 (1)
Somatostatin (1)
Testosterone (1)
TSH (4)
Utrophin (1)

Target Species

Human (78)
Mouse (5)
Rat (4)

Application

Protein Analysis & Detection (84)

Therapeutic Area

Angiogenesis (1)
Biologics/Bioprocess (4)
Cancer (4)
Central Nervous System (1)
Inflammation (5)
Metabolic (63)

Product Brand Name

AlphaLISA (55)
AlphaPlex (2)
LANCE Ultra (28)
Membrane Target Systems (1)
NEN Radiochemicals (42)
Quantum (1)

Detection Method

Alpha (57)
Radiometric (43)
Time-Resolved Fluorescence (TRF) (25)
TR-FRET (25)

Receptor Type

Ghrelin (1)

Assay Validated

Binding (1)

Radioisotope

C-14 (22)
H-3 (21)

Radionuclide

¹⁴C (22)
³H (21)

Label Position

Generally Labeled (2)
Nominally Labeled (12)
Specifically Labeled (20)
Uniformly Labeled (9)

Buffer

Aqueous (9)
Aqueous PT6-271 Stabilizer (1)
Ethanol : water (9)

Assay Points (200-50,000)

100 (29)
10000 (16)
500 (56)
5000 (41)

Assay Target Class

Cytokine (1)
GPCR (1)
Hormone (37)
Peptide (5)
Protein (44)

Automation Compatible

Yes (86)

Concentration

0.02 mCi/mL (1)
0.05 mCi/mL (1)
0.1 mCi/mL (9)
0.2 mCi/mL (4)
1 mCi/mL (14)

Experimental Type

In vitro (71)

Format

Microplates (68)

Host Cell

CHO-K1 (1)

Imaging Modality

microCT Imaging (1)

Volume

0-50 (11)
201-250 (4)

1-25 of 135 Products & Services

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Quantum GX2 microCT Imaging System

CLS149276

Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
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Glucose, D-[2-³H]

NET238C005MC , NET238C001MC

D-glucose, labeled with tritium. D-glucose can be incorporated into lipds, and provides a measurement of glucose transport. It is a metabolized tracer in glucose uptake studies.

Price Range : 1012.00 USD - 3132.00 USD
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Galactose 1-Phosphate, D-[¹⁴C(U)]

NEC579010UC , NEC579050UC

D-galactose 1-phosphate, labeled uniformly with carbon-14. This product is typically used in galactose metabolism studies.

Price Range : 1054.00 USD - 2727.00 USD
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Leptin (mouse) AlphaLISA Detection Kit

AL521C , AL521F

The AlphaLISA^® Mouse Leptin Detection Kit is designed for detection and quantitation of mouse leptin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 1539.00 USD - 10200.00 USD
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Glucose, D-[6-³H(N)]

NET100C005MC , NET100C001MC

D-glucose, labeled with tritium at C6. This product is supplied in 90% ethanol. D-glucose can be used for metabolic studies and glucose uptake.

Price Range : 668.00 USD - 2442.00 USD
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Glucose, D-[5-³H(N)]

NET531001MC , NET531005MC

D-glucose, labeled with tritium. D-glucose can be incorporated into lipds, and provides a measurement of glucose transport. It is a metabolized tracer in glucose uptake studies.

Price Range : 1635.00 USD - 3818.00 USD
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Deoxy-D-glucose, 2-[1-14C]-, EtOH Sol, Specific Activity: 45-60 mCi (1.66-2.22 GBq)/mmol,>97%

NEC495050UC , NEC495001MC , NEC495250UC

2-Deoxy-D-glucose, labeled with carbon-14 at C1. This product is supplied in 90% ethanol. Deoxy-D-glucose (DOG) is a glucose analog that is readily transported into most cells, is phosphorylated and trapped by the cells (unidirectional transport), and cannot be further metabolized. It is the most-common chemical used in glucose uptake assays.

Price Range : 1181.00 USD - 5400.00 USD
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Testosterone AlphaLISA Detection Kit

AL324C , AL324HV , AL324F

The AlphaLISA^® Testosterone Research Kit is designed for detection and quantitation of testosterone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 672.00 USD - 10500.00 USD
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Utrophin (human) AlphaLISA Detection Kit

AL3004F , AL3004HV , AL3004C

The AlphaLISA^® immunoassay kit for human utrophin enables the quantitative determination of utrophin in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 301.00 USD - 18800.00 USD
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Cortisol, liquid (LANCE)

TRF1314S

Cortisol standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Cortisol Detection Kit, but can also be ordered separately.

List Price : 782.00 USD
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Xylose, D-[U-¹⁴C]

NEC828250UC

250 µCi quantities of D-[U-¹⁴C]-Xylose are available for your research.

List Price : 8000.00 USD
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Deoxy-D-glucose, 2-[1,2-3H(N)]

NET549250UC , NET549001MC , NET549005MC

2-deoxy-D-glucose, labeled at the 1,2 position with tritium. This glucose analog is readily transported into most cells and cannot be further metabolized, and is commonly used in glucose uptake assays.

Price Range : 792.00 USD - 3050.00 USD
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Glucagon (human) LANCE Ultra TR-FRET Detection Kit

TRF1312C , TRF1312M

The LANCE^® Ultra Human Glucagon Detection Kit is designed for detection and quantitation of human glucagon in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 829.00 USD - 11100.00 USD
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TSH (human) AlphaLISA Detection Kit

AL3005C , AL3005F , AL3005HV

The AlphaLISA^® immunoassay kit for human TSH enables the quantitative determination of human thyroid stimulating hormone (TSH) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 644.00 USD - 19300.00 USD
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ApoA1 (human), lyophilized (LANCE)

TRF1389S

Human ApoA1 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human ApoA1 Detection Kit, but can also be ordered separately.

List Price : 308.00 USD
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Albumin (human) AlphaLISA Biotin-Free Detection Kit

AL363C , AL363HV , AL363F

The AlphaLISA^® Human Albumin Biotin-Free Detection Kit is designed for the quantitative detection of human albumin in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.

Price Range : 465.00 USD - 10200.00 USD
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Deoxy-D-glucose, 2-[1,2-³H(N)]

NET549A005MC , NET549A250UC , NET549A001MC

2-Deoxy-D-glucose, labeled with tritium at C1/C2. Deoxy-D-glucose (DOG) is a glucose analog that is readily transported into most cells, is phosphorylated and trapped by the cells (unidirectional transport), and cannot be further metabolized. It is the most-common chemical used in glucose uptake assays.

Price Range : 792.00 USD - 3327.00 USD
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IGF-1 (rat) AlphaLISA Detection Kit

AL552HV , AL552C , AL552F

The AlphaLISA^® immunoassay kit for rat IGF-1 enables the quantitative determination of rat insulin-like growth factor 1 (IGF-1) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 625.00 USD - 18800.00 USD
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Adiponectin (human) LANCE Ultra TR-FRET Detection Kit

TRF1209M , TRF1209C

The LANCE^® Ultra Human Adiponectin Detection Kit is designed for detection and quantitation of human adiponectin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 830.00 USD - 11100.00 USD
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Glycerol, [¹⁴C(U)]

NEC441X250UC , NEC441X050UC

Glycerol, uniformly labeled with C-14. ¹⁴C-glycerol is commonly used to label carbohydrates.

Price Range : 826.00 USD - 2812.00 USD
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Cortisol LANCE Ultra TR-FRET Detection Kit

TRF1314C , TRF1314M

The LANCE^® Ultra Cortisol Detection Kit is designed for detection and quantitation of cortisol in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 1624.00 USD - 11100.00 USD
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Apo-CIII (human), lyophilized (LANCE)

TRF1396S

Human Apo-CIII standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra ApoC3 Detection Kit, but can also be ordered separately.

List Price : 243.00 USD
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Albumin (human) LANCE Ultra TR-FRET Detection Kit

TRF1294C , TRF1294M

The LANCE^® Ultra Human Albumin Detection Kit is designed for detection and quantitation of human albumin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 829.00 USD - 11100.00 USD
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AlphaPlex-645 (Sm) Human Insulin Detection Kit

AP204SM-F , AP204SM-C , AP204SM-HV

The AlphaPlex™ 645 (Samarium) Human Insulin Detection Kit is designed for the quantitative determination of human insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.

Price Range : 480.00 USD - 10500.00 USD
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Chorionic gonadotropin (human) LANCE Ultra TR-FRET Detection Kit

TRF3001M , TRF3001C

The LANCE® Ultra Human Chorionic Gonadotropin (hCG) Detection Kit is designed for detection and quantitation of hCG in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 806.00 USD - 10700.00 USD

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