PerkinElmer

Metabolic Disease

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Metabolic diseases like diabetes are increasingly widespread, and research for this class of diseases relies on discovering and quantifying biomarkers to elucidate underlying mechanisms and uncover novel drug targets. Our portfolio of metabolic assays are well suited for metabolic disease research in vitro, in vivo, and in situ, and offer novel tools for your research workflow from start to finish.

Metabolic diseases are systemic and manifest with a variety of biological changes, from autophagy dysfunction to altered blood coagulation. For easy detection of a wide range of metabolic biomarkers, we offer fast and pre-validated metabolic assay reagents, kits, and imaging systems. For targeted binding studies, we also provide target-specific radiolabeled reagents.

Our products for metabolic disease research include:

  • LANCE® TR-FRET technology
  • AlphaLISA® immunoassay kits
  • Alpha reagents for AlphaLISA
  • DELFIA® TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Target-specific radiolabeled ligands, carbohydrates, lipids, and steroids

The range of tools offered allows for the detection and quantitation of many key biomolecules in metabolic disease research. Gain precise insight on disease biomarkers like c-reactive protein, fibrinogen, IGF, FGF, insulin and glucagon, leptin and ghrelin, adiponectin, and factor VIII.

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Product Type
  • Instruments (1)
  • Reagents (141)
  • Software and Informatics (4)
Assay Target
  • Adiponectin (3)
  • Albumin (5)
  • ApoA1 (4)
  • ApoB (2)
  • ApoC3 (2)
  • ApoE (2)
  • AST (1)
  • BMP-9 (1)
  • C-peptide (2)
  • CCL2 (1)
  • Corticosterone (2)
  • Cortisol (3)
  • Factor VIII (1)
  • FSH (3)
  • Ghrelin (4)
  • GLP-1 (2)
  • Glucagon (3)
  • Growth Hormone (1)
  • hCG (3)
  • HO-1 (1)
  • HO-2 (1)
  • IGF1 (5)
  • IGF2 (1)
  • Insulin (4)
  • KIM-1 (1)
  • LDH (1)
  • Leptin (5)
  • MANF (2)
  • MBNL1 (1)
  • NNMT (1)
  • Osteoprotegerin (1)
  • PCSK9 (1)
  • PIGF (1)
  • PON1 (1)
  • PON2 (1)
  • Progesterone (1)
  • PSMA (2)
  • SHP2 (1)
  • Somatostatin (1)
  • Testosterone (1)
  • TSH (4)
  • Utrophin (1)
Target Species
  • Human (76)
  • Mouse (5)
  • Rat (4)
Application
  • Protein Analysis & Detection (82)
Therapeutic Area
  • Angiogenesis (1)
  • Biologics/Bioprocess (4)
  • Cancer (4)
  • Central Nervous System (1)
  • Inflammation (4)
  • Metabolic (62)
Product Brand Name
  • AlphaLISA (52)
  • AlphaPlex (2)
  • LANCE Ultra (1)
  • LANCE Ultra (28)
  • Membrane Target Systems (1)
  • NEN Radiochemicals (55)
  • Quantum (1)
Detection Method
  • Alpha (55)
  • Radiometric (56)
  • Time-Resolved Fluorescence (TRF) (25)
  • TR-FRET (25)
Receptor Type
  • Ghrelin (1)
Assay Validated
  • Binding (1)
Radioisotope
  • C-14 (27)
  • H-3 (29)
Radionuclide
  • 14C (27)
  • 3H (29)
Label Position
  • Nominally Labeled (18)
  • Specifically Labeled (27)
  • Uniformly Labeled (11)
Buffer
  • Aqueous (10)
  • Aqueous PT6-271 Stabilizer (2)
  • Ethanol : water (11)
Assay points(200-50,000)
  • 100 (28)
  • 10000 (16)
  • 500 (55)
  • 5000 (40)
Assay Target Class
  • Cytokine (1)
  • GPCR (1)
  • Hormone (37)
  • Peptide (5)
  • Protein (42)
Automation Compatible
  • Yes (84)
Concentration
  • 0.02 mCi/mL (1)
  • 0.05 mCi/mL (1)
  • 0.1 mCi/mL (11)
  • 0.2 mCi/mL (4)
  • 1 mCi/mL (17)
Experimental Type
  • In vitro (70)
Format
  • Microplates (67)
Host Cell
  • CHO-K1 (1)
Imaging Modality
  • microCT Imaging (1)
Length
  • 901-1000 (1)
Pipetting Arms
Volume
  • 0-50 (16)
  • 201-250 (4)

"Metabolic Disease" 1-50 of 146 Products and Services

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Quantum GX2 microCT imaging system

Quantum GX2 microCT Imaging System

Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.

Somatostatin (human) AlphaLISA Detection Kit

The AlphaLISA® Somatostatin Detection Kit is designed for detection and quantitation of somatostatin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 725.00 USD - 10500.00 USD
AlphaLISA immunoassay kits

Factor VIII (human) AlphaLISA Detection Kit

The AlphaLISA® Human Factor VIII Detection Kit is designed for detection and quantitation of Human Factor VIII in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 672.00 USD - 10500.00 USD
AlphaLISA immunoassay kits

Heme oxygenase 2 AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human heme oxygenase 2 (HO-2) enables the quantitative determination of human HO-2 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 451.00 USD - 9900.00 USD

ApoA1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for ApoA1 is designed for the quantitative determination of ApoA1 in human serum, human plasma and cell supernantants using a homogeneous AlphaLISA assay (no wash steps). Neglible cross reactivity was observed with ApoCIII, ApoE, or ApoB.
Price Range : 644.00 USD - 19300.00 USD
Diclofenac sodium- Phenylacetic acid C14

Inulin, Carboxyl-, [Carboxyl-14C]

50 µCi quantities of [Carboxyl-14C]-Inulin-Carboxyl are available for your research. This product has a scheduled release date for the third Monday in July.
Price Range : 599.00 USD - 2970.00 USD
Adenosine 5 Triphosphate 250 µCi

Inositol, Myo,-[2-3H(N)]-, Aqueous/Steri-packaged

1 mCi quantities of Myo-[2-3H(N)]-Inositol are available for your research.
Price Range : 1928.00 USD - 4837.00 USD
AlphaLISA immunoassay kits

Heme oxygenase 1 AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human heme oxygenase 1 (HO-1) enables the quantitative determination of human HO-1 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 451.00 USD - 9900.00 USD
Adenosine 5 Triphosphate 250 µCi

Deoxy-D-glucose, 2-[1,2-3H(N)]

1 mCi quantities of Deoxy D Glucose (25-50 Ci/mmol) are available for your research.
List Price : 1259.00 USD

Albumin (human) AlphaLISA Biotin-Free Detection Kit

The AlphaLISA® Human Albumin Biotin-Free Detection Kit is designed for the quantitative detection of human albumin in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.
Price Range : 465.00 USD - 10200.00 USD
AlphaLISA assay principle

Osteoprotegerin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for total osteoprotegerin enables the quantitative determination of human osteoprotegerin in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 644.00 USD - 19300.00 USD
Protein

FSH (human), lyophilized (LANCE)

Human follicle stimulating hormone (FSH) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra FSH Detection Kit, but can also be ordered separately.
List Price : 308.00 USD
Adenosine 5 Triphosphate 250 µCi

Deoxy-D-glucose, 2-[1,2-3H (N)]-, in ethanol/water

250 µCi quantities of Deoxy D Glucose (5-10 Ci/mMole) are available for your research.
Price Range : 761.00 USD - 1192.00 USD
AlphaLISA immunoassay kits

PON-2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PON-2 enables the quantitative determination of human Paraoxonase 2 (PON-2) in buffered solution, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD
AlphaLISA immunoassay kits

Testosterone AlphaLISA Detection Kit

The AlphaLISA® Testosterone Research Kit is designed for detection and quantitation of testosterone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 672.00 USD - 10500.00 USD
Diclofenac sodium- Phenylacetic acid C14

Sucrose, [14C(U)]-Specific Activity: 400-700mCi (14.8-25.9GBq)/mmol, 250µCi (9.25MBq)

250 µCi quantities of [14C(U)]-Sucrose are available for your research.
List Price : 1344.00 USD
AlphaLISA immunoassay kits

FSH (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human FSH enables the quantitative determination of human follicle stimulating hormone in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 541.00 USD - 16200.00 USD
Diclofenac sodium- Phenylacetic acid C14

Glucose, D-[14C(U)]-, Specific Activity: 250-360 mCi/mmol

50 µCi quantities of D-[14C(U)]-Glucose are available for your research.
Price Range : 702.00 USD - 2504.00 USD
PerkinElmer

Membrane Target Systems: Ghrelin (human) membrane preparation, inCHO-K1 cells. 400 Units

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 867.00 USD
Adenosine 5 Triphosphate 250 µCi

Mannitol, D-[1-3H(N)]

250 µCi quantities of D-Mannitol are available for your research.
Price Range : 591.00 USD - 1056.00 USD
AlphaLISA immunoassay kits

Utrophin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human utrophin enables the quantitative determination of utrophin in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 301.00 USD - 18800.00 USD

Leptin (mouse) AlphaLISA Detection Kit

The AlphaLISA® Mouse Leptin Detection Kit is designed for detection and quantitation of mouse leptin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1539.00 USD - 10200.00 USD
AlphaLISA immunoassay kits

Corticosterone (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human corticosterone enables the quantitative determination of corticosterone in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 451.00 USD - 9900.00 USD

ApoA1 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human ApoA1 Detection Kit is designed for detection and quantitation of human Apolipoprotein A1 (ApoA1) in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 806.00 USD - 10700.00 USD
AlphaLISA immunoassay kits

Progesterone AlphaLISA Detection Kit

The AlphaLISA® Progesterone Detection Kit is designed for detection and quantitation of progesterone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 724.00 USD - 10500.00 USD
Alpha Bungarotoxin

Methyl α-D-glucopyranoside, [Glucose-14C(U)]-, 250µCi (9.25MBq)

250 µCi quantities of [Glucose-14C(U)]-Methyl α-D-glucopyranoside are available for your research.
List Price : 4020.00 USD
AlphaLISA immunoassay kits

ApoB (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human ApoB enables the quantitative determination of human apolipoprotein B in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 18800.00 USD
AlphaLISA immunoassay kits

Cortisol (human) AlphaLISA Detection Kit

AlphaLISA no-wash immunoassay kit for detection of human cortisol in buffer or serum.
Price Range : 725.00 USD - 10500.00 USD
LANCE Detection Kit

Cortisol LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Cortisol Detection Kit is designed for detection and quantitation of cortisol in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 1624.00 USD - 11100.00 USD

IGF-1 (rat) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for rat IGF-1 enables the quantitative determination of rat insulin-like growth factor 1 (IGF-1) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 18800.00 USD
AlphaLISA immunoassay kits

LDHA (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human lactate dehydrogenase subunit A (LDHA) enables the quantitative determination of human LDHA in cell lysates and serum using a homogeneous AlphaLISA assay (no wash steps). Please note this is NOT a cell cytotoxicity assay, as the assay does not measure secreted LDH.
Price Range : 759.00 USD - 14600.00 USD
AlphaLISA immunoassay kits

MBNL1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human muscleblind-like protein 1 (MBNL1) enables the quantitative determination of human MBNL1 in buffered solution and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 1821.00 USD - 14600.00 USD
Adenosine 5 Triphosphate 250 µCi

GLUCOSE, 3-0-[METHYL-D-1-3H]

3-O-Methyl-D-Glucose is a non-metabolizable glucose analogue that is not phosphorylated by hexokinase. 3-O-Methylglucose is used as a marker to assess glucose transport by evaluating its uptake within various cells and organ systems.
List Price : 1348.00 USD

SHP-2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human SHP-2 enables the quantitative determination of human Src-homology domain-2 containing protein tyrosine phosphatase 2 (SHP-2) in buffered solution, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD
AlphaLISA immunoassay kits

hCG (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human chorionic gonadotropin (hCG) enables the quantitative determination of hCG in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 541.00 USD - 16200.00 USD
AlphaLISA immunoassay kits

Insulin-like Growth Factor 2 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Insulin-like Growth Factor 2 (IGF2) Detection Kit is designed for detection and quantitation of human IGF2 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1585.00 USD - 10500.00 USD
Adenosine 5 Triphosphate 250 µCi

Inulin, Methoxy-, [Methoxy-3H]

250 µCi quantities of tritiated methoxy-inulin are available for your research.
Price Range : 735.00 USD - 2318.00 USD
Diclofenac sodium- Phenylacetic acid C14

Methyl-D-glucose, 3-O-[Methyl-14C]

50 µCi quantities of 3-0-[Methyl-14C]-Methyl-D-glucose are available for your research.
Price Range : 1005.00 USD - 3136.00 USD
Adenosine 5 Triphosphate 250 µCi

Inositol, Myo, -[2-3H(N)]-, Specific Activity: 10-25Ci (370-925GBq)/mmol, 250µCi (9.25MBq)

250 µCi quantities of Myo-[2-3H(N)]-Inositol are available for your research.
List Price : 788.00 USD
LANCE Detection Kit

FSH (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Follicle Stimulating Hormone (FSH) Detection Kit is designed for detection and quantitation of human FSH in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 806.00 USD - 10700.00 USD
Adenosine 5 Triphosphate 250 µCi

Glucose, D-[5-3H(N)]-, 1mCi (37MBq)

1 mCi quantities of D-[5-3H(N)]-Glucose are available for your research. 
List Price : 1635.00 USD
LANCE Detection Kit

ApoE (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human ApoE Detection Kit is designed for detection and quantitation of human Apolipoprotein E (ApoE) in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 806.00 USD - 10700.00 USD
AlphaLisa Analyte 2

PSMA (human), lyophilized (AlphaLISA)

Human prostate specific membrane antigen (PSMA) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human PSMA Detection Kit, but can also be ordered separately.
List Price : 308.00 USD
Diclofenac sodium- Phenylacetic acid C14

Methyl α-D-glucopyranoside, [Glucose-14C(U)]-, 50µCi (1.85MBq)

50 µCi quantities of [Glucose-14C(U)]-Methyl α-D-glucopyranoside are available for your research.
List Price : 1195.00 USD

PSMA (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PSMA enables the quantitative determination of human prostate specific membrane antigen (PSMA) in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 15000.00 USD
LANCE Detection Kit

Glucagon (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Glucagon Detection Kit is designed for detection and quantitation of human glucagon in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 829.00 USD - 11100.00 USD
AlphaPlex Samarium immunoassay kits

AlphaPlex-645 (Sm) Human Insulin Detection Kit

The AlphaPlex™ 645 (Samarium) Human Insulin Detection Kit is designed for the quantitative determination of human insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.
Price Range : 480.00 USD - 10500.00 USD
Protein

Adiponectin (human), lyophilized (LANCE)

Human adiponectin standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human Adiponectin TR-FRET Detection Kit, but can be ordered separately.
List Price : 250.00 USD
LANCE Detection Kit

IGF-1 (rat) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Rat IGF-1 Detection Kit is designed for detection and quantitation of rat insulin-like growth factor 1 (IGF-1) in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 806.00 USD - 10700.00 USD

MYO INOSITOL,-[2-3H]

5 mCi quantities of Myo-[2-3H]-Inositol are available for your research.
List Price : 7200.00 USD

"Metabolic Disease" 1-50 of 146 Products and Services

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