Metabolic Disease

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Metabolic diseases like diabetes are increasingly widespread, and research for this class of diseases relies on discovering and quantifying biomarkers to elucidate underlying mechanisms and uncover novel drug targets. Our portfolio of metabolic assays are well suited for metabolic disease research in vitro, in vivo, and in situ, and offer novel tools for your research workflow from start to finish.

Metabolic diseases are systemic and manifest with a variety of biological changes, from autophagy dysfunction to altered blood coagulation. For easy detection of a wide range of metabolic biomarkers, we offer fast and pre-validated metabolic assay reagents, kits, and imaging systems. For targeted binding studies, we also provide target-specific radiolabeled reagents.

Our products for metabolic disease research include:

LANCE^® TR-FRET technology
AlphaLISA^® immunoassay kits
Alpha reagents for AlphaLISA
DELFIA^® TRF technology
Cellular, tissue, and in vivo imaging systems
Target-specific radiolabeled ligands, carbohydrates, lipids, and steroids

The range of tools offered allows for the detection and quantitation of many key biomolecules in metabolic disease research. Gain precise insight on disease biomarkers like c-reactive protein, fibrinogen, IGF, FGF, insulin and glucagon, leptin and ghrelin, adiponectin, and factor VIII.

Products & Services (128)
Technical Resources (173)
Tools & More (13)
Business Insights (4)

Products & Services (128)

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Product Type

Instruments (1)
Reagents (124)
Software and Informatics (3)

Assay Target

Adiponectin (3)
Albumin (5)
ApoA1 (4)
ApoB (2)
ApoC3 (2)
ApoE (2)
AST (1)
BMP-9 (1)
C-peptide (2)
CCL2 (1)
Corticosterone (2)
Cortisol (3)
CYCS (1)
Factor VIII (1)
FSH (3)
Ghrelin (4)
GLP-1 (2)
Glucagon (3)
Growth Hormone (1)
hCG (3)
HO-1 (1)
HO-2 (1)
IGF1 (5)
IGF2 (1)
Insulin (4)
KIM-1 (1)
LDH (1)
Leptin (5)
MANF (2)
MBNL1 (1)
NNMT (1)
Osteoprotegerin (1)
PCSK9 (1)
PIGF (1)
PON1 (1)
PON2 (1)
Progesterone (1)
SHP2 (1)
Testosterone (1)
TSH (4)

Application

Protein Analysis & Detection (79)

Therapeutic Area

Angiogenesis (1)
Biologics/Bioprocess (4)
Cancer (2)
Inflammation (4)
Metabolic (62)

Product Brand Name

AlphaLISA (50)
AlphaPlex (2)
LANCE Ultra (28)
Membrane Target Systems (1)
NEN Radiochemicals (41)
Quantum (1)

Detection Method

Alpha (52)
Radiometric (42)
Time-Resolved Fluorescence (TRF) (25)
TR-FRET (25)

Receptor Type

Ghrelin (1)

Assay Validated

Binding (1)

Radioisotope

C-14 (22)
H-3 (20)

Radionuclide

¹⁴C (22)
³H (20)

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Generally Labeled (2)
Nominally Labeled (12)
Specifically Labeled (19)
Uniformly Labeled (9)

Assay Points (200-50,000)

100 (27)
10000 (16)
500 (54)
5000 (39)

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Cytokine (1)
GPCR (1)
Hormone (35)
Peptide (4)
Protein (41)

Automation Compatible

Yes (81)

Concentration

0.02 mCi/mL (1)
0.05 mCi/mL (1)
0.1 mCi/mL (9)
0.2 mCi/mL (4)
1 mCi/mL (13)

Experimental Type

In vitro (68)

Format

Microplates (63)

Host Cell

CHO-K1 (1)

Imaging Modality

microCT Imaging (1)

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0-50 (10)
201-250 (4)

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1-25 of 128 Products & Services

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Quantum GX2 microCT Imaging System

CLS149276

Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
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IGF-1 (rat) AlphaLISA Detection Kit

AL552HV , AL552F , AL552C

The AlphaLISA^® immunoassay kit for rat IGF-1 enables the quantitative determination of rat insulin-like growth factor 1 (IGF-1) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 715.00 USD - 21400.00 USD
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Progesterone AlphaLISA Detection Kit

AL335C , AL335F , AL335HV

The AlphaLISA^® Progesterone Detection Kit is designed for detection and quantitation of progesterone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 828.00 USD - 12000.00 USD
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Albumin (human) AlphaLISA Biotin-Free Detection Kit

AL363HV , AL363F , AL363C

The AlphaLISA^® Human Albumin Biotin-Free Detection Kit is designed for the quantitative detection of human albumin in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.

Price Range : 531.00 USD - 11600.00 USD
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Cortisol (human) AlphaLISA Detection Kit

AL314F , AL314C , AL314HV

AlphaLISA no-wash immunoassay kit for detection of human cortisol in buffer or serum.

Price Range : 829.00 USD - 12000.00 USD
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FSH (human), lyophilized (LANCE)

TRF1394S

Human follicle stimulating hormone (FSH) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra FSH Detection Kit, but can also be ordered separately.

List Price : 321.00 USD
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Adiponectin (human) LANCE Ultra TR-FRET Detection Kit

TRF1209C , TRF1209M

The LANCE^® Ultra Human Adiponectin Detection Kit is designed for detection and quantitation of human adiponectin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 865.00 USD - 11500.00 USD
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Leptin (mouse) AlphaLISA Detection Kit

AL521F , AL521C

The AlphaLISA^® Mouse Leptin Detection Kit is designed for detection and quantitation of mouse leptin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 1759.00 USD - 11700.00 USD
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NNMT (human) AlphaLISA Detection Kit

AL3079C , AL3079F , AL3079HV

The AlphaLISA^® immunoassay kit for human Nicotinamide N-Methyltransferase (NNMT) enables the quantitative determination of human NNMT in buffered solution, cell culture media, and serum using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 867.00 USD - 16700.00 USD
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ApoA1 (human) AlphaLISA Detection Kit

AL389HV , AL389F , AL389C

The AlphaLISA^® immunoassay kit for ApoA1 is designed for the quantitative determination of ApoA1 in human serum, human plasma and cell supernantants using a homogeneous AlphaLISA assay (no wash steps). Neglible cross reactivity was observed with ApoCIII, ApoE, or ApoB.

Price Range : 736.00 USD - 22100.00 USD
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Corticosterone (human) AlphaLISA Detection Kit

AL3020C , AL3020HV , AL3020F

The AlphaLISA^® immunoassay kit for human corticosterone enables the quantitative determination of corticosterone in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 515.00 USD - 11300.00 USD
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Inulin, Methoxy-, [Methoxy-³H]

NET086L001MC , NET086L250UC

Methoxy-inulin, labeled on methoxy groups with tritium. ³H-methoxyinulin is commonly used to measure glomerular fitration rates (GFR) or as an extracellular space marker.

Price Range : 812.00 USD - 2559.00 USD
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Osteoprotegerin (human) AlphaLISA Detection Kit

AL3010HV , AL3010F , AL3010C

The AlphaLISA^® immunoassay kit for total osteoprotegerin enables the quantitative determination of human osteoprotegerin in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 736.00 USD - 22100.00 USD
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AlphaPlex-645 (Sm) Human Insulin Detection Kit

AP204SM-F , AP204SM-C , AP204SM-HV

The AlphaPlex™ 645 (Samarium) Human Insulin Detection Kit is designed for the quantitative determination of human insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.

Price Range : 549.00 USD - 12000.00 USD
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SHP-2 (human) AlphaLISA Detection Kit

AL3074F , AL3074HV , AL3074C

The AlphaLISA^® immunoassay kit for human SHP-2 enables the quantitative determination of human Src-homology domain-2 containing protein tyrosine phosphatase 2 (SHP-2) in buffered solution, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 867.00 USD - 16700.00 USD
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Mannitol, D-[1-³H(N)]

NET101250UC , NET101001MC

D-mannitol, labeled with tritium at C1. Tritiated manitol is commonly used as an extracellular space marker.

Price Range : 682.00 USD - 1272.00 USD
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MANF (human) AlphaLISA Detection Kit

AL3009HV , AL3009F , AL3009C

The AlphaLISA^® immunoassay kit for human MANF enables the quantitative determination of mesencephalic astrocyte-derived neurotrophic factor (MANF) in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 736.00 USD - 22100.00 USD
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Albumin (mouse) AlphaLISA Detection Kit

AL508C , AL508F

The AlphaLISA^® Mouse Albumin Detection Kit is designed for the quantitative detection of mouse albumin in serum, urine, buffered solution or cell culture medium, using a homogeneous (no wash steps, no separation steps) assay.

Price Range : 3470.00 USD - 27100.00 USD
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Galactose, D-[1-¹⁴C]

NEC302X050UC

50 µCi quantities of D-[1-¹⁴C]-Galactose are available for your research.

List Price : 1636.00 USD
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Leptin (mouse), lyophilized (LANCE)

TRF1521S

Mouse leptin standard, lyophilized, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Mouse Leptin Detection Kit, but can be ordered separately.

List Price : 261.00 USD
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ApoE (human) LANCE Ultra TR-FRET Detection Kit

TRF1395C , TRF1395M

The LANCE® Ultra Human ApoE Detection Kit is designed for detection and quantitation of human Apolipoprotein E (ApoE) in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 840.00 USD - 11200.00 USD
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TSH (human) AlphaLISA Detection Kit

AL3005HV , AL3005C , AL3005F

The AlphaLISA^® immunoassay kit for human TSH enables the quantitative determination of human thyroid stimulating hormone (TSH) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 736.00 USD - 22100.00 USD
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PIGF (human) AlphaLISA Detection Kit

AL3030C , AL3030HV , AL3030F

The AlphaLISA^® immunoassay kit for human placental growth factor (PIGF) enables the quantitative determination of human PIGF (PGF) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 515.00 USD - 11300.00 USD
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CCL2 (human) LANCE Ultra TR-FRET Detection Kit

TRF1244M , TRF1244C

The LANCE^® Ultra Human CCL2/MCP-1 Detection Kit is designed for detection and quantitation of human CCL2/MCP-1 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 865.00 USD - 11500.00 USD
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Cytochrome C (human) AlphaLISA Detection Kit

AL3124C , AL3124HV , AL3124F

The AlphaLISA^® immunoassay kit for human cytochrome C (CYCS) enables the quantitative determination of cytochrome C in buffer, liver and kidney cytosol, and liver mitochondria fraction using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 893.00 USD - 20000.00 USD