Metabolic Disease

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Metabolic diseases like diabetes are increasingly widespread, and research for this class of diseases relies on discovering and quantifying biomarkers to elucidate underlying mechanisms and uncover novel drug targets. Our portfolio of metabolic assays are well suited for metabolic disease research in vitro, in vivo, and in situ, and offer novel tools for your research workflow from start to finish.

Metabolic diseases are systemic and manifest with a variety of biological changes, from autophagy dysfunction to altered blood coagulation. For easy detection of a wide range of metabolic biomarkers, we offer fast and pre-validated metabolic assay reagents, kits, and imaging systems. For targeted binding studies, we also provide target-specific radiolabeled reagents.

Our products for metabolic disease research include:

LANCE^® TR-FRET technology
AlphaLISA^® immunoassay kits
Alpha reagents for AlphaLISA
DELFIA^® TRF technology
Cellular, tissue, and in vivo imaging systems
Target-specific radiolabeled ligands, carbohydrates, lipids, and steroids

The range of tools offered allows for the detection and quantitation of many key biomolecules in metabolic disease research. Gain precise insight on disease biomarkers like c-reactive protein, fibrinogen, IGF, FGF, insulin and glucagon, leptin and ghrelin, adiponectin, and factor VIII.

Products & Services (132)
Technical Resources (162)
Tools & More (13)
Business Insights (4)

Products & Services (132)

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Instruments (1)
Reagents (128)
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Assay Target

Adiponectin (3)
Albumin (5)
ApoA1 (4)
ApoB (2)
ApoC3 (2)
ApoE (2)
AST (1)
BMP-9 (1)
C-peptide (2)
CCL2 (1)
Corticosterone (2)
Cortisol (3)
CYCS (1)
Factor VIII (1)
FSH (3)
Ghrelin (4)
GLP-1 (2)
Glucagon (3)
Growth Hormone (1)
hCG (3)
HO-1 (1)
HO-2 (1)
IGF1 (5)
IGF2 (1)
Insulin (4)
KIM-1 (1)
LDH (1)
Leptin (5)
MANF (2)
MBNL1 (1)
NNMT (1)
Osteoprotegerin (1)
PCSK9 (1)
PIGF (1)
PON1 (1)
PON2 (1)
Progesterone (1)
PSMA (2)
SHP2 (1)
Somatostatin (1)
Testosterone (1)
TSH (4)
Utrophin (1)

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Protein Analysis & Detection (83)

Therapeutic Area

Angiogenesis (1)
Biologics/Bioprocess (4)
Cancer (4)
Central Nervous System (1)
Inflammation (4)
Metabolic (63)

Product Brand Name

AlphaLISA (54)
AlphaPlex (2)
LANCE Ultra (28)
Membrane Target Systems (1)
NEN Radiochemicals (41)
Quantum (1)

Detection Method

Alpha (56)
Radiometric (42)
Time-Resolved Fluorescence (TRF) (25)
TR-FRET (25)

Receptor Type

Ghrelin (1)

Assay Validated

Binding (1)

Radioisotope

C-14 (22)
H-3 (20)

Radionuclide

¹⁴C (22)
³H (20)

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Generally Labeled (2)
Nominally Labeled (12)
Specifically Labeled (19)
Uniformly Labeled (9)

Buffer

Aqueous (9)
Aqueous PT6-271 Stabilizer (1)
Ethanol : water (9)

Assay Points (200-50,000)

100 (29)
10000 (16)
500 (56)
5000 (41)

Assay Target Class

Cytokine (1)
GPCR (1)
Hormone (37)
Peptide (5)
Protein (43)

Automation Compatible

Yes (85)

Concentration

0.02 mCi/mL (1)
0.05 mCi/mL (1)
0.1 mCi/mL (9)
0.2 mCi/mL (4)
1 mCi/mL (13)

Experimental Type

In vitro (70)

Format

Microplates (67)

Host Cell

CHO-K1 (1)

Imaging Modality

microCT Imaging (1)

Volume

0-50 (10)
201-250 (4)

1-25 of 132 Products & Services

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Quantum GX2 microCT Imaging System

CLS149276

Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
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Insulin (human) AlphaLISA Detection Kit

AL350HV , AL350C , AL350F

The AlphaLISA^® Human Insulin Detection Kit is designed for detection and quantitation of human insulin in cell culture supernatants, serum, and plasma using a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 725.00 USD - 10200.00 USD
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TSH (human), lyophilized (LANCE)

TRF3005S

Human thyroid stimulating hormone (TSH) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human TSH Detection Kit, but can also be ordered separately.

List Price : 250.00 USD
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Cytochrome C (human) AlphaLISA Detection Kit

AL3124C , AL3124F , AL3124HV

The AlphaLISA^® immunoassay kit for human cytochrome C (CYCS) enables the quantitative determination of cytochrome C in buffer, liver and kidney cytosol, and liver mitochondria fraction using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 782.00 USD - 17500.00 USD
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SHP-2 (human) AlphaLISA Detection Kit

AL3074C , AL3074F , AL3074HV

The AlphaLISA^® immunoassay kit for human SHP-2 enables the quantitative determination of human Src-homology domain-2 containing protein tyrosine phosphatase 2 (SHP-2) in buffered solution, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 759.00 USD - 14600.00 USD
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Deoxy-D-glucose, 2-[1,2-3H(N)]

NET549001MC , NET549250UC , NET549005MC

2-deoxy-D-glucose, labeled at the 1,2 position with tritium. This glucose analog is readily transported into most cells and cannot be further metabolized, and is commonly used in glucose uptake assays.

Price Range : 792.00 USD - 3050.00 USD
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Galactose 1-Phosphate, D-[¹⁴C(U)]

NEC579010UC , NEC579050UC

D-galactose 1-phosphate, labeled uniformly with carbon-14. This product is typically used in galactose metabolism studies.

Price Range : 1054.00 USD - 2727.00 USD
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Glycerol, [¹⁴C(U)]

NEC441X250UC , NEC441X050UC

Glycerol, uniformly labeled with C-14. ¹⁴C-glycerol is commonly used to label carbohydrates.

Price Range : 826.00 USD - 2812.00 USD
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Myo-inositol,-[2-3H]

NET1156005MC , NET1156001MC

Myoinositol, labeled with tritium. ³H-myo-inositol is commonly used in inositol phosphate accumulation studies.

Price Range : 3123.00 USD - 7200.00 USD
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GLP-1 (7-36) (human) LANCE Ultra TR-FRET Detection Kit

TRF1215M , TRF1215C

The LANCE® Ultra Human GLP-1 (7-36) Detection Kit is designed for detection and quantitation of human GLP-1 (7-36) in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 829.00 USD - 11100.00 USD
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Testosterone AlphaLISA Detection Kit

AL324HV , AL324C , AL324F

The AlphaLISA^® Testosterone Research Kit is designed for detection and quantitation of testosterone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 672.00 USD - 10500.00 USD
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MANF (human) AlphaLISA Detection Kit

AL3009C , AL3009F , AL3009HV

The AlphaLISA^® immunoassay kit for human MANF enables the quantitative determination of mesencephalic astrocyte-derived neurotrophic factor (MANF) in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 644.00 USD - 19300.00 USD
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TSH (human) LANCE Ultra TR-FRET Detection Kit

TRF3005C , TRF3005M

The LANCE^® Ultra Human TSH Detection Kit is designed for detection and quantitation of human thyroid stimulating hormone in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 830.00 USD - 11100.00 USD
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Sucrose, [¹⁴C(U)]-, Specific Activity: 400-700mCi (14.8-25.9GBq)/mmol

NEC100X050UC , NEC100X250UC , NEC100X001MC

Sucrose, labeled with C-14. ¹⁴C-sucrose is commonly used to study blood-brain barrier permeability.

Price Range : 553.00 USD - 3280.00 USD
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Uridine diphospho-D-glucose, [6-³H]-, 250 µCi

NET1163250UC

250 µCi quantities of [6-³H]-Uridine Diphospho-D-Glucose are available for your research.

List Price : 2182.00 USD
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AST (human) AlphaLISA Detection Kit

AL3078C , AL3078F , AL3078HV

The AlphaLISA^® immunoassay kit for human AST enables the quantitative determination of human aspartate transaminase (AST) in buffered solution, cell culture media, and serum using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 759.00 USD - 14600.00 USD
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Inulin, Carboxyl-, [Carboxyl-¹⁴C]

NEC164A050UC , NEC164A250UC

Inulin-carboxyl, labeled on carboxyl groups with C-14. Inulin-carboxyl-14C is commonly used in renal cearance studies.

Price Range : 599.00 USD - 2970.00 USD
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Glucose, D-[¹⁴C(U)]-, Specific Activity: 250-360 mCi/mmol

NEC042X050UC , NEC042X001MC , NEC042X250UC

D-glucose, uniformly labeled with C-14. This product is supplied in 90% ethanol. D-glucose can be used for metabolic studies and glucose uptake.

Price Range : 702.00 USD - 2504.00 USD
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TSH (human) AlphaLISA Detection Kit

AL3005C , AL3005HV , AL3005F

The AlphaLISA^® immunoassay kit for human TSH enables the quantitative determination of human thyroid stimulating hormone (TSH) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 644.00 USD - 19300.00 USD
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Utrophin (human) AlphaLISA Detection Kit

AL3004HV , AL3004C , AL3004F

The AlphaLISA^® immunoassay kit for human utrophin enables the quantitative determination of utrophin in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 301.00 USD - 18800.00 USD
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FSH (human) LANCE Ultra TR-FRET Detection Kit

TRF1394C , TRF1394M

The LANCE® Ultra Human Follicle Stimulating Hormone (FSH) Detection Kit is designed for detection and quantitation of human FSH in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 806.00 USD - 10700.00 USD
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AlphaPlex™ 545 Human Insulin Detection Kit

AP204TB-C , AP204TB-HV , AP204TB-F

The AlphaPlex™ 545 (Terbium) Human Insulin Detection Kit is designed for the quantitative determination of human Insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous assay.

Price Range : 480.00 USD - 10500.00 USD
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Glucose, D-[5-³H(N)]

NET531001MC , NET531005MC

D-glucose, labeled with tritium. D-glucose can be incorporated into lipds, and provides a measurement of glucose transport. It is a metabolized tracer in glucose uptake studies.

Price Range : 1635.00 USD - 3818.00 USD
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Glucose, D-[2-³H]

NET238C001MC , NET238C005MC

D-glucose, labeled with tritium. D-glucose can be incorporated into lipds, and provides a measurement of glucose transport. It is a metabolized tracer in glucose uptake studies.

Price Range : 1012.00 USD - 3132.00 USD
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Cortisol (human) AlphaLISA Detection Kit

AL314HV , AL314C , AL314F

AlphaLISA no-wash immunoassay kit for detection of human cortisol in buffer or serum.

Price Range : 725.00 USD - 10500.00 USD