PerkinElmer

Metabolic Disease

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Metabolic diseases like diabetes are increasingly widespread, and research for this class of diseases relies on discovering and quantifying biomarkers to elucidate underlying mechanisms and uncover novel drug targets. Our portfolio of metabolic assays are well suited for metabolic disease research in vitro, in vivo, and in situ, and offer novel tools for your research workflow from start to finish.

Metabolic diseases are systemic and manifest with a variety of biological changes, from autophagy dysfunction to altered blood coagulation. For easy detection of a wide range of metabolic biomarkers, we offer fast and pre-validated metabolic assay reagents, kits, and imaging systems. For targeted binding studies, we also provide target-specific radiolabeled reagents.

Our products for metabolic disease research include:

  • LANCE® TR-FRET technology
  • AlphaLISA® immunoassay kits
  • Alpha reagents for AlphaLISA
  • DELFIA® TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Target-specific radiolabeled ligands, carbohydrates, lipids, and steroids

The range of tools offered allows for the detection and quantitation of many key biomolecules in metabolic disease research. Gain precise insight on disease biomarkers like c-reactive protein, fibrinogen, IGF, FGF, insulin and glucagon, leptin and ghrelin, adiponectin, and factor VIII.

Products & Services (136)
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Product Type
  • Instruments (1)
  • Reagents (132)
  • Software and Informatics (3)
Assay Target
  • Acetyl CoA carboxylase (1)
  • Adiponectin (3)
  • Albumin (5)
  • AMPKα1/2 (1)
  • ApoA1 (4)
  • ApoB (2)
  • ApoC3 (2)
  • ApoE (2)
  • AST (1)
  • BMP-9 (1)
  • C-peptide (2)
  • CCL2 (1)
  • Corticosterone (2)
  • Cortisol (3)
  • ERK1/2 (1)
  • Factor VIII (1)
  • FSH (3)
  • Ghrelin (4)
  • GLP-1 (2)
  • Glucagon (1)
  • Growth Hormone (1)
  • hCG (3)
  • HO-1 (1)
  • HO-2 (1)
  • IGF1 (5)
  • IGF2 (1)
  • Insulin (4)
  • JNK1/2 (1)
  • KIM-1 (1)
  • LDH (1)
  • Leptin (5)
  • MANF (2)
  • MBNL1 (1)
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  • Osteoprotegerin (2)
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  • PIGF (1)
  • PON1 (1)
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  • Rb (1)
  • RB (2)
  • Ribosmal Protein S6 (1)
  • Ribosomal Protein S6 (2)
  • S6 Ribosomal Protein (1)
  • SHP2 (1)
  • SMAD2 (1)
  • Testosterone (1)
  • TSH (4)
Application
  • Protein Analysis & Detection (81)
  • Protein Detection (7)
Therapeutic Area
  • Angiogenesis (1)
  • Biologics/Bioprocess (4)
  • Cancer (2)
  • Inflammation (9)
  • Metabolic (58)
  • Metabolic Disorders (1)
  • Metabolism (7)
  • Oncology (8)
Product Brand Name
  • Alpha SureFire Multiplex (3)
  • Alpha SureFire Ultra Multiplex (4)
  • AlphaLISA (49)
  • AlphaLISA SureFire Ultra (4)
  • AlphaPlex (2)
  • LANCE Ultra (26)
  • Membrane Target Systems (1)
  • NEN Radiochemicals (40)
  • Quantum (1)
Detection Method
  • Alpha (63)
  • Radiometric (41)
  • Time-Resolved Fluorescence (TRF) (23)
  • TR-FRET (23)
Receptor Type
  • Ghrelin (1)
Assay Validated
  • Binding (1)
Radioisotope
  • C-14 (23)
  • H-3 (18)
Radionuclide
  • 14C (1)
  • 14C (22)
  • 3H (18)
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  • 2 positions (1)
  • Dual labeled at 1 (1)
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Assay Points (200-50,000)
  • 100 (37)
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  • 5000 (37)
  • 50000 (12)
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  • Cytokine (1)
  • GPCR (1)
  • Hormone (32)
  • Peptide (4)
  • Phospho-protein (1)
  • Phosphoprotein (8)
  • Protein (52)
Automation Compatible
  • Yes (90)
Concentration
  • 0.02 mCi/mL (1)
  • 0.05 mCi/mL (1)
  • 0.1 mCi/mL (10)
  • 0.2 mCi/mL (4)
  • 1 mCi/mL (13)
Experimental Type
  • In vitro (79)
Format
  • Microplates (61)
Host Cell
  • CHO-K1 (1)
Imaging Modality
  • microCT Imaging (1)
Volume
  • 0-50 (10)
  • 201-250 (4)

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1-25 of 136 Products & Services

  • Quantum GX2 microCT imaging system

    Quantum GX2 microCT Imaging System

    Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
  • LANCE Ultra Biomarker

    Leptin (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human Leptin Detection Kit is designed for detection and quantitation of human leptin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 865.00 USD - 11500.00 USD
  • PIGF (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human placental growth factor (PIGF) enables the quantitative determination of human PIGF (PGF) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 515.00 USD - 11300.00 USD
  • Alpha SureFire Ultra Multiplex Phospho/Total ERK1/2 Assay Kit

    The AlphaLISA® SureFire® Ultra™ Multiplex phospho-ERK1/2 (Thr202/Tyr204) + Total ERK assay kit is used to measure both the phosphorylation of ERK1/2 and total levels of endogenous ERK1/2 in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure ERK1/2phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
    Price Range : 946.00 USD - 60600.00 USD
  • PerkinElmer

    ApoA1 (human), lyophilized (LANCE)

    Human ApoA1 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human ApoA1 Detection Kit, but can also be ordered separately.
    List Price : 321.00 USD
  • AlphaLISA Sandwich Anti-AnalyteConjugatedAcceptorBead

    Growth Hormone (human) AlphaLISA Detection Kit

    The AlphaLISA® Human Growth Hormone Detection Kit is designed for detection and quantitation of human growth hormone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1935.00 USD - 12000.00 USD
  • Diclofenac sodium- Phenylacetic acid C14

    Galactose 1-Phosphate, D-[14C(U)]

    D-galactose 1-phosphate, labeled uniformly with carbon-14. This product is typically used in galactose metabolism studies.
    Price Range : 1164.00 USD - 3284.00 USD
  • Alpha Terbium SureFire Ultra Multiplex MPSU
    New

    Alpha SureFire Ultra Multiplex Phospho (Ser780)/Total Rb Assay Kit

    The AlphaLISA® SureFire® Ultra Multiplex phospho-Rb (Ser780) + Total Rb assay kit is used to measure both the phosphorylation of Rb and total levels of endogenous Rb in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure Rb phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.

    Price Range : 946.00 USD - 60600.00 USD
  • Adiponectin (human) AlphaLISA Detection Kit

    The AlphaLISA® Human Adiponectin Detection Kit is designed for detection and quantitation of human adiponectin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1811.00 USD - 12000.00 USD
  • Leptin (human) AlphaLISA Detection Kit

    The AlphaLISA® Human Leptin Detection Kit is designed for detection and quantitation of human leptin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. Due to the presence of leptin binding proteins in serum or other matrices, an acid-dissociation step might be required before performing the AlphaLISA assay.
    Price Range : 1811.00 USD - 12000.00 USD
  • ApoA1 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for ApoA1 is designed for the quantitative determination of ApoA1 in human serum, human plasma and cell supernantants using a homogeneous AlphaLISA assay (no wash steps). Neglible cross reactivity was observed with ApoCIII, ApoE, or ApoB.
    Price Range : 736.00 USD - 22100.00 USD
  • AlphaPlex Terbium immunoassay kits

    AlphaPlex™ 545 Human Insulin Detection Kit

    The AlphaPlex™ 545 (Terbium) Human Insulin Detection Kit is designed for the quantitative determination of human Insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous assay.
    Price Range : 549.00 USD - 12000.00 USD
  • PerkinElmer

    Chorionic gonadotropin (human), lyophilized (LANCE)

    Human chorionic gonadotropin (hCG) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra hCG Detection Kit, but can also be ordered separately.
    List Price : 321.00 USD
  • Adenosine 5 Triphosphate 250 µCi

    Glucose, D-[3-3H]-, EtOH Sol, Specific Activity: 10-20 Ci (370-740 GBq)/mmol

    D-glucose, labeled with tritium at C3. This product is supplied in 90% ethanol. Specifically-labeled glucose can be used for metabolic studies and glucose uptake.
    Price Range : 870.00 USD - 4030.00 USD
  • AlphaLISA Sandwich Anti-AnalyteConjugatedAcceptorBead

    Osteoprotegerin (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for total osteoprotegerin enables the quantitative determination of human osteoprotegerin in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 736.00 USD - 22100.00 USD
  • AlphaPlex Samarium immunoassay kits

    AlphaPlex-645 (Sm) Human Insulin Detection Kit

    The AlphaPlex™ 645 (Samarium) Human Insulin Detection Kit is designed for the quantitative determination of human insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.
    Price Range : 549.00 USD - 12000.00 USD
  • Alpha Terbium SureFire Ultra Multiplex MPSU
    New

    Alpha SureFire Ultra Multiplex Phospho (Ser807/811)/Total Rb Assay Kit

    The AlphaLISA® SureFire® Ultra Multiplex phospho-Rb (Ser807/811) + Total Rb assay kit is used to measure both the phosphorylation of Rb and total levels of endogenous Rb in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure Rb phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.

    Price Range : 946.00 USD - 60600.00 USD
  • Diclofenac sodium- Phenylacetic acid C14

    Glycerol, [14C(U)]

    Glycerol, uniformly labeled with C-14. 14C-glycerol is commonly used to label carbohydrates.
    Price Range : 912.00 USD - 3104.00 USD
  • Diclofenac sodium- Phenylacetic acid C14

    Deoxy-D-glucose, 2-[1-14C]-, Aqueous Sol, Specific Activity: 45-60 mCi (1.66-2.22 GBq)/mmol,>97%

    2-Deoxy-D-glucose, labeled with carbon-14 at C1. This product is supplied steri-packaged in an aqueous solution. Deoxy-D-glucose (DOG) is a glucose analog that is readily transported into most cells, is phosphorylated and trapped by the cells (unidirectional transport), and cannot be further metabolized. It is the most-common chemical used in glucose uptake assays.
    Price Range : 1303.00 USD - 5200.00 USD
  • Adenosine 5 Triphosphate 250 µCi

    Deoxy-D-glucose, 2-[1,2-3H (N)]-, Aqueous Sol, Specific Activity: 5-10 Ci (185-370 GBq)/mmol

    2-Deoxy-D-glucose, nominally labeled with tritium at C1/C2. This product is supplied steri-packaged in an aqueous solution. Deoxy-D-glucose (DOG) is a glucose analog that is readily transported into most cells, is phosphorylated and trapped by the cells (unidirectional transport), and cannot be further metabolized. It is the most-common chemical used in glucose uptake assays.
    Price Range : 840.00 USD - 1315.00 USD
  • LANCE Ultra Biomarker

    Chorionic gonadotropin (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human Chorionic Gonadotropin (hCG) Detection Kit is designed for detection and quantitation of hCG in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 840.00 USD - 11200.00 USD
  • C-peptide (human) AlphaLISA Kit

    AlphaLISA® no-wash immunoassay kit for detection of human C-peptide (human connecting peptide) in serum, buffered solution or cell culture medium.
    Price Range : 1759.00 USD - 11700.00 USD
  • AlphaLISA SureFire Ultra total-protein

    Total JNK1/2 AlphaLISA SureFire Ultra Detection Kit

    The AlphaLISA® SureFire® Ultra™ total JNK1/2 assay is a sandwich immunoassay for quantitative detection of JNK1/2 (phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be a normalization phosphorylation studies.

    Price Range : 526.00 USD - 34900.00 USD
  • AlphaLISA SureFire Ultra Phospho-protein
    New

    Phospho-S6 Ribosomal Protein (Ser235/236) AlphaLISA SureFire Ultra Detection Kit

    The AlphaLISA® SureFire® Ultra p-Ribosomal Protein S6 (Ser235/236) assay is a sandwich immunoassay for quantitative detection of phospho- Ribosomal Protein S6 (phosphorylated on Ser3235/236) in cellular lysates using Alpha Technology.

    Price Range : 526.00 USD - 34900.00 USD
  • Alpha SureFire Ultra Multiplex Phospho/Total SMAD2 Assay Kit

    The AlphaLISA® SureFire® Ultra™ Multiplex phospho-SMAD2 (Ser465/467) + Total SMAD2 assay kit is used to measure both the phosphorylation of SMAD2 and total levels of endogenous SMAD2 in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure SMAD2 phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
    Price Range : 946.00 USD - 60600.00 USD
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