PerkinElmer

Metabolic Disease

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Metabolic diseases like diabetes are increasingly widespread, and research for this class of diseases relies on discovering and quantifying biomarkers to elucidate underlying mechanisms and uncover novel drug targets. Our portfolio of metabolic assays are well suited for metabolic disease research in vitro, in vivo, and in situ, and offer novel tools for your research workflow from start to finish.

Metabolic diseases are systemic and manifest with a variety of biological changes, from autophagy dysfunction to altered blood coagulation. For easy detection of a wide range of metabolic biomarkers, we offer fast and pre-validated metabolic assay reagents, kits, and imaging systems. For targeted binding studies, we also provide target-specific radiolabeled reagents.

Our products for metabolic disease research include:

  • LANCE® TR-FRET technology
  • AlphaLISA® immunoassay kits
  • Alpha reagents for AlphaLISA
  • DELFIA® TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Target-specific radiolabeled ligands, carbohydrates, lipids, and steroids

The range of tools offered allows for the detection and quantitation of many key biomolecules in metabolic disease research. Gain precise insight on disease biomarkers like c-reactive protein, fibrinogen, IGF, FGF, insulin and glucagon, leptin and ghrelin, adiponectin, and factor VIII.

Products & Services (135)
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Product Type
  • Instruments (1)
  • Reagents (130)
  • Software and Informatics (4)
Assay Target
  • Adiponectin (3)
  • Albumin (5)
  • ApoA1 (4)
  • ApoB (2)
  • ApoC3 (2)
  • ApoE (2)
  • AST (1)
  • BMP-9 (1)
  • C-peptide (2)
  • CCL2 (1)
  • Corticosterone (2)
  • Cortisol (3)
  • CYCS (1)
  • Factor VIII (1)
  • FSH (3)
  • Ghrelin (4)
  • GLP-1 (2)
  • Glucagon (3)
  • Growth Hormone (1)
  • hCG (3)
  • HO-1 (1)
  • HO-2 (1)
  • IGF1 (5)
  • IGF2 (1)
  • Insulin (4)
  • KIM-1 (1)
  • LDH (1)
  • Leptin (5)
  • MANF (2)
  • MBNL1 (1)
  • NNMT (1)
  • Osteoprotegerin (2)
  • PCSK9 (1)
  • PIGF (1)
  • PON1 (1)
  • PON2 (1)
  • Progesterone (1)
  • PSMA (2)
  • SHP2 (1)
  • Somatostatin (1)
  • Testosterone (1)
  • TSH (4)
  • Utrophin (1)
Target Species
  • Human (78)
  • Mouse (5)
  • Rat (4)
Application
  • Protein Analysis & Detection (84)
Therapeutic Area
  • Angiogenesis (1)
  • Biologics/Bioprocess (4)
  • Cancer (4)
  • Central Nervous System (1)
  • Inflammation (5)
  • Metabolic (63)
Product Brand Name
  • AlphaLISA (55)
  • AlphaPlex (2)
  • LANCE Ultra (28)
  • Membrane Target Systems (1)
  • NEN Radiochemicals (42)
  • Quantum (1)
Detection Method
  • Alpha (57)
  • Radiometric (43)
  • Time-Resolved Fluorescence (TRF) (25)
  • TR-FRET (25)
Receptor Type
  • Ghrelin (1)
Assay Validated
  • Binding (1)
Radioisotope
  • C-14 (22)
  • H-3 (21)
Radionuclide
  • 14C (22)
  • 3H (21)
Label Position
  • Generally Labeled (2)
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Buffer
  • Aqueous (9)
  • Aqueous PT6-271 Stabilizer (1)
  • Ethanol : water (9)
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  • 100 (29)
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  • Cytokine (1)
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  • Hormone (37)
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Automation Compatible
  • Yes (86)
Concentration
  • 0.02 mCi/mL (1)
  • 0.05 mCi/mL (1)
  • 0.1 mCi/mL (9)
  • 0.2 mCi/mL (4)
  • 1 mCi/mL (14)
Experimental Type
  • In vitro (71)
Format
  • Microplates (68)
Host Cell
  • CHO-K1 (1)
Imaging Modality
  • microCT Imaging (1)
Volume
  • 0-50 (11)
  • 201-250 (4)

1-25 of 135 Products & Services

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  • Quantum GX2 microCT imaging system

    Quantum GX2 microCT Imaging System

    Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
  • Adenosine 5 Triphosphate 250 µCi

    Glucose, D-[2-3H]

    D-glucose, labeled with tritium. D-glucose can be incorporated into lipds, and provides a measurement of glucose transport. It is a metabolized tracer in glucose uptake studies.
    Price Range : 1012.00 USD - 3132.00 USD
  • Diclofenac sodium- Phenylacetic acid C14

    Galactose 1-Phosphate, D-[14C(U)]

    D-galactose 1-phosphate, labeled uniformly with carbon-14. This product is typically used in galactose metabolism studies.
    Price Range : 1054.00 USD - 2727.00 USD
  • AlphaLISA immunoassay kits

    Leptin (mouse) AlphaLISA Detection Kit

    The AlphaLISA® Mouse Leptin Detection Kit is designed for detection and quantitation of mouse leptin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1539.00 USD - 10200.00 USD
  • Adenosine 5 Triphosphate 250 µCi

    Glucose, D-[6-3H(N)]

    D-glucose, labeled with tritium at C6. This product is supplied in 90% ethanol. D-glucose can be used for metabolic studies and glucose uptake.
    Price Range : 668.00 USD - 2442.00 USD
  • Adenosine 5 Triphosphate 250 µCi

    Glucose, D-[5-3H(N)]

    D-glucose, labeled with tritium. D-glucose can be incorporated into lipds, and provides a measurement of glucose transport. It is a metabolized tracer in glucose uptake studies.
    Price Range : 1635.00 USD - 3818.00 USD
  • Diclofenac sodium- Phenylacetic acid C14

    Deoxy-D-glucose, 2-[1-14C]-, EtOH Sol, Specific Activity: 45-60 mCi (1.66-2.22 GBq)/mmol,>97%

    2-Deoxy-D-glucose, labeled with carbon-14 at C1. This product is supplied in 90% ethanol. Deoxy-D-glucose (DOG) is a glucose analog that is readily transported into most cells, is phosphorylated and trapped by the cells (unidirectional transport), and cannot be further metabolized. It is the most-common chemical used in glucose uptake assays.
    Price Range : 1181.00 USD - 5400.00 USD
  • AlphaLISA immunoassay kits

    Testosterone AlphaLISA Detection Kit

    The AlphaLISA® Testosterone Research Kit is designed for detection and quantitation of testosterone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 672.00 USD - 10500.00 USD
  • Utrophin (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human utrophin enables the quantitative determination of utrophin in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 301.00 USD - 18800.00 USD
  • Protein

    Cortisol, liquid (LANCE)

    Cortisol standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Cortisol Detection Kit, but can also be ordered separately.
    List Price : 782.00 USD
  • Xylose, D-[U-14C]

    250 µCi quantities of D-[U-14C]-Xylose are available for your research.
    List Price : 8000.00 USD
  • Adenosine 5 Triphosphate 250 µCi

    Deoxy-D-glucose, 2-[1,2-3H(N)]

    2-deoxy-D-glucose, labeled at the 1,2 position with tritium. This glucose analog is readily transported into most cells and cannot be further metabolized, and is commonly used in glucose uptake assays.
    Price Range : 792.00 USD - 3050.00 USD
  • LANCE Detection Kit

    Glucagon (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human Glucagon Detection Kit is designed for detection and quantitation of human glucagon in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 829.00 USD - 11100.00 USD
  • AlphaLISA assay principle

    TSH (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human TSH enables the quantitative determination of human thyroid stimulating hormone (TSH) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 644.00 USD - 19300.00 USD
  • Protein

    ApoA1 (human), lyophilized (LANCE)

    Human ApoA1 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human ApoA1 Detection Kit, but can also be ordered separately.
    List Price : 308.00 USD
  • AlphaLISA immunoassay kits

    Albumin (human) AlphaLISA Biotin-Free Detection Kit

    The AlphaLISA® Human Albumin Biotin-Free Detection Kit is designed for the quantitative detection of human albumin in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.
    Price Range : 465.00 USD - 10200.00 USD
  • Adenosine 5 Triphosphate 250 µCi

    Deoxy-D-glucose, 2-[1,2-3H(N)]

    2-Deoxy-D-glucose, labeled with tritium at C1/C2. Deoxy-D-glucose (DOG) is a glucose analog that is readily transported into most cells, is phosphorylated and trapped by the cells (unidirectional transport), and cannot be further metabolized. It is the most-common chemical used in glucose uptake assays.
    Price Range : 792.00 USD - 3327.00 USD
  • AlphaLISA immunoassay kits

    IGF-1 (rat) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for rat IGF-1 enables the quantitative determination of rat insulin-like growth factor 1 (IGF-1) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 625.00 USD - 18800.00 USD
  • Adiponectin (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human Adiponectin Detection Kit is designed for detection and quantitation of human adiponectin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 830.00 USD - 11100.00 USD
  • Diclofenac sodium- Phenylacetic acid C14

    Glycerol, [14C(U)]

    Glycerol, uniformly labeled with C-14. 14C-glycerol is commonly used to label carbohydrates.
    Price Range : 826.00 USD - 2812.00 USD
  • LANCE Detection Kit

    Cortisol LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Cortisol Detection Kit is designed for detection and quantitation of cortisol in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 1624.00 USD - 11100.00 USD
  • Protein

    Apo-CIII (human), lyophilized (LANCE)

    Human Apo-CIII standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra ApoC3 Detection Kit, but can also be ordered separately.
    List Price : 243.00 USD
  • LANCE Detection Kit

    Albumin (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human Albumin Detection Kit is designed for detection and quantitation of human albumin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 829.00 USD - 11100.00 USD
  • AlphaPlex Samarium immunoassay kits

    AlphaPlex-645 (Sm) Human Insulin Detection Kit

    The AlphaPlex™ 645 (Samarium) Human Insulin Detection Kit is designed for the quantitative determination of human insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.
    Price Range : 480.00 USD - 10500.00 USD
  • Chorionic gonadotropin (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human Chorionic Gonadotropin (hCG) Detection Kit is designed for detection and quantitation of hCG in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 806.00 USD - 10700.00 USD
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