PerkinElmer

Ligands

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Eliminate the need for antibodies and reduce assay time with direct detection using our radiolabeled ligands, which provide for sensitive and quantitative measurement of binding.

  • High specific activity — The majority of our 125I-labeled ligands are offered at maximum specific activity. This means virtually every molecule of ligand provided in the stock vial is radiolabeled. For tritiated ligands (3H ligands), pick a ligand with specific activity above 20 Ci/mmol – all of our tritiated ligands meets or exceeds these requirements.
  • High purity — We offer highly-pure radioligands for the highest specific signal with low background in binding assays.
  • High selectivity — Our broad portfolio of agonists and antagonists offers many options for choosing the most selective compound for your receptor.
  • Validated for receptor binding — all of our radioligand products are tested for receptor binding during development. Additionally, many of our radioligands are used to QC our GPCR and receptor cell lines and cell membrane products.

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"Ligands" 1-50 of 116 Products and Services

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MESULERGINE, [N-METHYL-3H]-, 250 µCi

Mesulergine, tritiated on the N-methyl group. Mesulergine acts as an antagonist at serotonin 5-HT2A and 5-HT2C receptors, and as a partial agonist at dopamine receptors.
List Price : 2221.00 USD
Adenosine 5 Triphosphate 250 µCi

DOFETILIDE, [N-METHYL-3H], 100 µCi

Dofetilide, tritiated at the N-methyl position. Dofetilide is a selective potassium channel (hERG) blocker.
List Price : 1733.00 USD

Butyl Bicyclophosphorothionate, Tertiary-[35S]

Tertiary-Butylbicyclophosphorothionate (TBPS), radiolabeled with S-35. TBPS is a GABAA receptor antagonist.
Price Range : 2204.00 USD - 3891.00 USD
Adenosine 5 Triphosphate 250 µCi

CGP 39653, [Propyl-2,3,3H]

CGP 39653, tritiated at the propyl-2,3 position. CGP 39653 acts as an N-methyl-D-aspartate (NMDA) antagonist.
Price Range : 702.00 USD - 6000.00 USD
Adenosine 5 Triphosphate 250 µCi

Ethylcarboxamidoadenosine, 5`-N-[Adenine-2,8-3H]-, 250µCi (9.25MBq)

5'-N-Ethylcarboxamidoadenosine (NECA), tritiated at the adenine-2,8 position. 5'-N-Ethylcarboxamidoadenosine is an adenosine analog that acts as an agonist at adenosine receptors A1, A2A, and A3.
List Price : 1739.00 USD
Adenosine 5 Triphosphate 250 µCi

Rosiglitazone, DL- [3H]-

Tritiated DL-Rosiglitazone (Avandia). Rosiglitazone acts as a selective agonist at peroxisome proliferator-activated receptors (PPARs).
List Price : 1827.00 USD
Adenosine 5 Triphosphate 250 µCi

Astemizole, [O-Methyl-3H]

Astemizole (Hismanal) tritiated at the O-methyl group. Atemizole is an antagonist of the histamine H1-receptor and has been shown to block hERG potassium channels.
Price Range : 771.00 USD - 8700.00 USD
Adenosine 5 Triphosphate 250 µCi

MELATONIN, [0-METHYL-3H]

Melatonin, tritiated on the o-methyl group. Melatonin is the endogenous ligand that binds and activates melatonin receptors.
List Price : 2883.00 USD
Adenosine 5 Triphosphate 250 µCi

CCK-8(SULPHATED), [3H]PROPIONY, 50 µCi

CCK-8, tritiated at the propionyl position. Sulphated CCK8 is a peptide hormone that can bind both cholecystokinin B and cholecystokinin A receptors.
List Price : 1865.00 USD
Adenosine 5 Triphosphate 250 µCi

Oxytocin, [Tyrosyl-3,5-3H]-, 50µCi (1.85MBq)

Oxytocin, tritiated on the tyrosyl group. Oxytocin is a neurotransmitter that binds and activates oxytocin receptors.
List Price : 1544.00 USD

AH5183, L-[PIPERIDINYL-3,4-3H]-(VESAMICOL), 250 µCi

AH5183 (vesamicol) radioligand tritiated at the piperidinyl-3,4 position. AH5183 is an acetylcholine transport blocker.
List Price : 1152.00 USD
Adenosine 5 Triphosphate 250 µCi

PK 11195, [N-Methyl-3H]

PK-11195, tritiated on the N-methyl group. PK-11195 binds selectively to the peripheral benzodiazepine receptor (PBR).
Price Range : 2200.00 USD - 4926.00 USD
Adenosine 5 Triphosphate 250 µCi

Prazosin, [7-Methoxy-3H]

Prazosin, tritiated at the 7-methoxy position. Prazosin acts as an inverse agonist at the α1-adrenergic receptor.
Price Range : 768.00 USD - 6100.00 USD
Adenosine 5 Triphosphate 250 µCi

Scopolamine Methyl Chloride, [N-methyl-3H]

Scopolamine methyl chloride, tritiated on the N-methyl group. Scopolamine acts as an antagonist at muscarinic acetylcholine receptors.
Price Range : 1663.00 USD - 3814.00 USD
Adenosine 5 Triphosphate 250 µCi

Verapamil Hydrochloride, [N-Methyl-3H]

Verapamil hydrochloride, tritiated on the N-methyl group. Verapamil acts as a calcium channel blocker (CCB).
Price Range : 748.00 USD - 3600.00 USD
Adenosine 5 Triphosphate 250 µCi

Norepinephrine, Levo-[ring-2,5,6-3H]

Levo-Norepinephrine, tritiated on the ring group. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET).
Price Range : 1458.00 USD - 9300.00 USD
Adenosine 5 Triphosphate 250 µCi

Diltiazem, cis-(+)-[N-Methyl-3H]

cis-(+)-Diltiazem, tritiated at the N-methyl position. Diltiazem is a non-DHP calcium channel blocker.
Price Range : 1801.00 USD - 4593.00 USD

WAY100635, [METHOXY-3H], 250 uCi

WAY-100635, tritiated on the methoxy group. WAY-100635 acts as an antagonist at serotonin 5-HT1A receptors. It also acts as an agonist at dopamine D4 receptors. WAY-100635 is on a scheduled release and is available on the second Monday in February and August. 
List Price : 4364.00 USD
Adenosine 5 Triphosphate 250 µCi

RX 821002, [6,7-3H(N)]-

RX 821002, tritiated at the 6,7 position. RX 821002 acts as an antagonist at α2-adrenoceptors.
List Price : 2560.00 USD
Diclofenac sodium- Phenylacetic acid C14

Hydroxytryptamine Binoxalate (Serotonin Binoxalate), 5-[1-14C]

5-Hydroxytryptamine Binoxalate (Serotonin Binoxalate), labeled with C-14 at the 1-position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors. NEC855 replaces product NEC225, which was labeled at the 2-position.
Price Range : 839.00 USD - 4082.00 USD
Adenosine 5 Triphosphate 250 µCi

Flunitrazepam, [Methyl-3H]

Flunitrazepam (Rohypnol), tritiated on the methyl group. Flunitrazepam is a benzodiazepine and acts as an agonist at GABAA (γ-aminobutyric acid) receptors.
Price Range : 582.00 USD - 5800.00 USD
Diclofenac sodium- Phenylacetic acid C14

DICLOFENAC SODIUM[PHENYLACETIC ACID RING- U-14C]

Diclofenac sodium, labeled with C-14 on the phenylacetic acid ring. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that acts as an antagonist at peroxisome prolifeator-activated receptor gamma (PPAR-γ or PPARG).
List Price : 2577.00 USD
Adenosine 5 Triphosphate 250 µCi

DAMGO, [Tyrosyl-3,5-3H(N)]

DAMGO, tritiated at the tyrosyl 3,5 poisition. DAMGO is a synthetic opioid analog with high specificity for the μ-opioid receptor.
Price Range : 1892.00 USD - 4893.00 USD
Adenosine 5 Triphosphate 250 µCi

U-69,593, [Phenyl-3,4-3H]

U-69,593, tritiated at the phenyl-3,4 position. U-69,593 is a selective κ1-opioid receptor agonist.
Price Range : 760.00 USD - 2478.00 USD

MK-912, [3H(G)]

MK-912 radioligand. MK-912 acts as a selective antagonist at the α2-adrenoceptor. This product has a scheduled lot release for the second Monday in October. NOTE: NET1227025UC will be obsoleted soon.
List Price : 3462.00 USD
Adenosine 5 Triphosphate 250 µCi

Dihydroxyphenylethylamine (Dopamine), 3,4-[Ring-2,5,6-3H]

Dihydroxyphenylethylamine (dopamine, DA), tritiated at the ring-2,5,6- position. Dihydroxyphenylethylamine is a neurotransmitter and is the primary endogenous ligand for dopamine receptors.
Price Range : 704.00 USD - 1708.00 USD
Diclofenac sodium- Phenylacetic acid C14

Iodoantipyrine, 4-[N-Methyl-14C]

4-Iodoantipyrine, labeled with C-14 on the N-methyl group. Iodoantipyrine has been used to measure cerebral blood flow.
Price Range : 775.00 USD - 6400.00 USD
Adenosine 5 Triphosphate 250 µCi

Citalopram, [N-Methyl-3H]

Citalopram, tritiated at the N-methyl group. Citalopram is a selective serotonin reuptake inhibitor (SSRI) antidpressant drug, and has been shown to block the serotonin transporter (SERT, 5-HTT).
Price Range : 1218.00 USD - 2660.00 USD
Adenosine 5 Triphosphate 250 µCi

Norepinephrine Hydrochloride, DL-[7-3H(N)]-, 250µCi (9.25MBq)

DL-Norepinephrine hydrochloride, tritiated at the 7 position. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET).
List Price : 1260.00 USD
Adenosine 5 Triphosphate 250 µCi

AF-DX 384, [2,3-Dipropylamino-3H]-, 250µCi (9.25MBq)

AFDX-384 (BIBN-161) radioligand tritiated at the 2,3-dipropylamino position. AFDX-384 acts as a selective antagonist of muscarinic acetylcholine receptors, with selectivity for the M2 and M4 subtypes.
List Price : 2140.00 USD
Adenosine 5 Triphosphate 250 µCi

GR 65630, [N-Methyl-3H]

GR 65630, tritiated on the N-methyl group. GR 65630 acts as a selective antagonist at the 5-HT3 receptor.
Price Range : 706.00 USD - 4055.00 USD
Adenosine 5 Triphosphate 250 µCi

Enkephalin, [Tyrosyl-2,6-3H(N)]- (2-D-Penicillamine, 5-D-Penicillamine) (DPDPE)

2-D-Penicillamine, 5-D-Penicillamine (DPDPE), tritiated on the tyrosyl group. Cyclic peptide, sequence: Tyr-D-Pen-Gly-Phe-D-Pen-OH. DPDPE is a synthetic enkephalin opioid peptide that acts as an agonist at delta opiate receptors (δ-opioid receptor, DOR). This product has a scheduled lot release for the second Monday in February and August.
Price Range : 1068.00 USD - 5200.00 USD
Adenosine 5 Triphosphate 250 µCi

Paroxetine, [Phenyl-6'-3H]

Paroxetine (Paxil), tritiated at the phenyl-6' position. Paroxetine is a selective serotonin reuptake inhibitor (SSRI). This product has a scheduled lot release for the first Monday in May and November.
Price Range : 682.00 USD - 3867.00 USD
Adenosine 5 Triphosphate 250 µCi

3-INDOLYLACETIC ACID, [5-3H(N)]-

3-Indolyacetic acid tritiated at the 5 position. Indole-3-acetic acid (IAA, 3-IAA) is the most common, naturally occurring, plant hormone of the auxin class.
List Price : 1609.00 USD
Adenosine 5 Triphosphate 250 µCi

Nitrendipine, [5-Methyl-3H]-, 25µCi (925kBq)

Nitrendipine, tritiated on the 5-methyl group. Nitrendipine is a dihydropyridine calcium channel blocker.
List Price : 1162.00 USD
Adenosine 5 Triphosphate 250 µCi

CP 55940, [Side Chain-2,3,4-3H(N)]

CP 55,940, tritiated on the side chain-2,3-4 position. CP 55,940 is a synthetic cannabinoid that acts as a full agonist at both cannabinoid CB1 and CB2 receptors, and can also upregulate serotonin 5-HT2A receptors.
Price Range : 736.00 USD - 6100.00 USD
Adenosine 5 Triphosphate 250 µCi

α-BUNGAROTOXIN,N-[3H]

α-Bungarotoxin (α-BTX) radioligand tritiated on the propionyl group. α-BTX acts as an antagonist at nicotinic acetylcholine receptors. α-Bungarotoxin,N-[3H] is part of a scheduled release program and is available on the second Monday in August.
List Price : 6600.00 USD
Adenosine 5 Triphosphate 250 µCi

Ketanserin Hydrochloride (R41 468), [Ethylene-3H]

Ketanserin hydrochloride (Sufrexal; R41468), tritiated on the ethylene group. Ketanserin is a high-affinity non-selective antagonist of 5-HT2 receptors.
Price Range : 676.00 USD - 2245.00 USD
Adenosine 5 Triphosphate 250 µCi

RO 15-4513, [7,9-3H]-, 250µCi (9.25MBq)

Ro15-4513, tritiated at the 7,9 position. Ro15-4513 is a partial inverse agonist at GABAA receptors.
List Price : 2645.00 USD
Adenosine 5 Triphosphate 250 µCi

SB-269970, [3H]

Tritiated SB-269970. SB-269970 is believed to act as a selective serotonin 5-HT7 antagonist, or possibly an inverse agonist.
List Price : 4240.00 USD
Adenosine 5 Triphosphate 250 µCi

Glibenclamide, Glyburide, [Cyclohexyl-2,3-3H(N)]-, 250µCi (9.25MBq)

Glibenclamide (glyburide) tritiated at the cyclohexyl-2,3 position. Glibenclamide is an antidiabetic drug that binds and inhibits the ATP-sensitive potassium channel.
List Price : 3178.00 USD
Adenosine 5 Triphosphate 250 µCi

Colchicine, [ring C, Methoxy-3H]-, 250µCi (9.25MBq)

Colchicine, tritiated at the ring C methoxy- position. Colchicine binds tubulin to prevent microtubule polymerization, and is used to treat gout.
List Price : 2634.00 USD
Adenosine 5 Triphosphate 250 µCi

Methylhistamine Dihydrochloride, N-α-[methyl-3H]-, 250µCi (9.25MBq)

(R)-α-methylhistamine dihydrochloride, tritiated on the methyl group. α-Methylhistamine is a histamine agonist selective for the histamine H3 receptor.
List Price : 1312.00 USD
Adenosine 5 Triphosphate 250 µCi

Kainic acid, [Isopropenyl-3H]

Kainic acid, tritiated on the isoproprenyl group. Kainic acid acts as an agonist at kainate glutamate receptors.
Price Range : 2187.00 USD - 5800.00 USD
Adenosine 5 Triphosphate 250 µCi

Dihydroalprenolol Hydrochloride, Levo-[Ring, Propyl-3H(N)]

Dihydroalprenolol hydrochloride, tritiated on the ring propyl group. Dihydroalprenolol (DHA) is an alprenolol derivative that binds to beta-adrenergic receptors and acts as a beta-adrenergic blocker.
Price Range : 1077.00 USD - 2449.00 USD
Adenosine 5 Triphosphate 250 µCi

Oxotremorine-M Acetate, [Methyl-3H]-,>97%, 250µCi (9.25MBq)

Oxotremorine-M acetate, tritiated on the methyl group. Oxotremorine-M acts as a selective agonist at muscarinic acetylcholine receptors.
List Price : 2517.00 USD
Adenosine 5 Triphosphate 250 µCi

Lysergic Acid Diethylamide, [N-Methyl-3H]-, 250µCi (9.25MBq)

Lysergic Acid Diethylamide (LSD), tritiated on the N-methyl group. LSD is a partial agonist of dopamine D2 receptors. It also binds most serotonin receptors (5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT5B and 5-HT6). This product has a scheduled lot release for the second Monday in April, August and December.
List Price : 2167.00 USD

WIN 35428, [N-Methyl-3H]

WIN 35428 [(–)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane], tritiated on the N-methyl group. WIN 35428 acts as an antagonist at dopamine transporters (DATs).
Price Range : 775.00 USD - 5600.00 USD
Adenosine 5 Triphosphate 250 µCi

TCP, [Piperdyl-3,4-3H(N)]

Tenocyclidine (TCP), tritiated at the piperdyl-3,4 position. TCP acts as an antagonist at N-methyl-D-aspartate receptor (NMDA receptors).
Price Range : 712.00 USD - 2950.00 USD
Adenosine 5 Triphosphate 250 µCi

Hemicholinium-3 Diacetate Salt, [Methyl-3H]-, 250µCi (9.25MBq)

Hemicholinium-3 (HC3; hemicholine) Diacetate Salt, tritiated on the methyl group. Hemicholinium-3 blocks reuptake of choline by the high-affinity choline transporter. This product has a scheduled lot release for the second Monday in February and August.
List Price : 3542.00 USD

"Ligands" 1-50 of 116 Products and Services

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