PerkinElmer

Ligands

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Eliminate the need for antibodies and reduce assay time with direct detection using our radiolabeled ligands, which provide for sensitive and quantitative measurement of binding.

  • High specific activity — The majority of our 125I-labeled ligands are offered at maximum specific activity. This means virtually every molecule of ligand provided in the stock vial is radiolabeled. For tritiated ligands (3H ligands), pick a ligand with specific activity above 20 Ci/mmol – all of our tritiated ligands meets or exceeds these requirements.
  • High purity — We offer highly-pure radioligands for the highest specific signal with low background in binding assays.
  • High selectivity — Our broad portfolio of agonists and antagonists offers many options for choosing the most selective compound for your receptor.
  • Validated for receptor binding — all of our radioligand products are tested for receptor binding during development. Additionally, many of our radioligands are used to QC our GPCR and receptor cell lines and cell membrane products.

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"Ligands" 1-50 of 119 Products and Services

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Adenosine 5 Triphosphate 250 µCi

GABAPENTIN [3H]

Tritiated gabapentin (Neurontin). Gabapentin is a medication used to treat epilepsy, and has been shown to cross membrane lipid barriers via system L-amino acid transporters and bind to voltage-gated calcium channels in the central nervous system. This product has a scheduled release for the third Monday in February and September.
List Price : 5300.00 USD
Adenosine 5 Triphosphate 250 µCi

CGS 21680, [Carboxyethyl-3H(N)]

CGS 21680, tritiated at the carboxyethyl group. CGS 21680 acts as an agonist for the adenosine A2A receptor, but can also bind adenosine A1 and A3.
Price Range : 1831.00 USD - 4415.00 USD
Adenosine 5 Triphosphate 250 µCi

SPIPERONE, [3H]

Tritiated Spiperone. Spiperone acts as an antagonist at Dopamine D2 and D3 receptors, 5-HT1A, 5-HT2A, and alpha-adrenergic receptors (α adrenoreceptors).
List Price : 1889.00 USD
Adenosine 5 Triphosphate 250 µCi

AF-DX 384, [2,3-Dipropylamino-3H]-, 250µCi (9.25MBq)

AFDX-384 (BIBN-161) radioligand tritiated at the 2,3-dipropylamino position. AFDX-384 acts as a selective antagonist of muscarinic acetylcholine receptors, with selectivity for the M2 and M4 subtypes.
List Price : 1945.00 USD
Adenosine 5 Triphosphate 250 µCi

Kainic acid, [Isopropenyl-3H]

Kainic acid, tritiated on the isoproprenyl group. Kainic acid acts as an agonist at kainate glutamate receptors.
Price Range : 568.00 USD - 5300.00 USD
Adenosine 5 Triphosphate 250 µCi

RO 15-4513, [7,9-3H]-, 250µCi (9.25MBq)

Ro15-4513, tritiated at the 7,9 position. Ro15-4513 is a partial inverse agonist at GABAA receptors.
List Price : 2405.00 USD
Adenosine 5 Triphosphate 250 µCi

Enkephalin (2-D-Alanine-5-D-Leucine), [Tyrosyl-3,5-3H(N)]-, 250µCi (9.25MBq)

DADLE, tritiated on the tyrosyl group. Peptide sequence: Tyr-D-Ala-Gly-L-Phe-D-Leu. DADLE is a synthetic enkephalin analog considered selective for the delta opioid receptor, but has been shown to bind the mu opioid receptor as well.
List Price : 1683.00 USD
Adenosine 5 Triphosphate 250 µCi

Ro 15-1788, [N-Methyl-3H]

Ro 15-1788 (flumazenil), tritiated on the N-methyl group. Ro 15-1788 acts as a selective benzodiazepine antagonist.
Price Range : 648.00 USD - 4858.00 USD

WIN 35428, [N-Methyl-3H]

WIN 35428 [(–)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane], tritiated on the N-methyl group. WIN 35428 acts as an antagonist at dopamine transporters (DATs).
Price Range : 705.00 USD - 5100.00 USD
Adenosine 5 Triphosphate 250 µCi

Paroxetine, [Phenyl-6'-3H]

Paroxetine (Paxil), tritiated at the phenyl-6' position. Paroxetine is a selective serotonin reuptake inhibitor (SSRI). This product has a scheduled lot release for the first Monday in May and November.
Price Range : 620.00 USD - 2762.00 USD
Adenosine 5 Triphosphate 250 µCi

Astemizole, [O-Methyl-3H]

Astemizole (Hismanal) tritiated at the O-methyl group. Atemizole is an antagonist of the histamine H1-receptor and has been shown to block hERG potassium channels.
Price Range : 701.00 USD - 7000.00 USD

Butyl Bicyclophosphorothionate, Tertiary-[35S]

Tertiary-Butylbicyclophosphorothionate (TBPS), radiolabeled with S-35. TBPS is a GABAA receptor antagonist.
Price Range : 2003.00 USD - 3538.00 USD
Adenosine 5 Triphosphate 250 µCi

Histamine Dihydrochloride, [Ring, Methylenes-3H(N)]

Histamine dihydrochloride, tritiated on the ring and methylene groups. Histamine is an endogenous agonist of histamine receptors.
Price Range : 1080.00 USD - 2349.00 USD
Adenosine 5 Triphosphate 250 µCi

Diltiazem, cis-(+)-[N-Methyl-3H]

cis-(+)-Diltiazem, tritiated at the N-methyl position. Diltiazem is a non-DHP calcium channel blocker.
Price Range : 1638.00 USD - 3674.00 USD
Adenosine 5 Triphosphate 250 µCi

Enkephalin, [Tyrosyl-2,6-3H(N)]- (2-D-Penicillamine, 5-D-Penicillamine) (DPDPE)

2-D-Penicillamine, 5-D-Penicillamine (DPDPE), tritiated on the tyrosyl group. Cyclic peptide, sequence: Tyr-D-Pen-Gly-Phe-D-Pen-OH. DPDPE is a synthetic enkephalin opioid peptide that acts as an agonist at delta opiate receptors (δ-opioid receptor, DOR). This product has a scheduled lot release for the second Monday in February and August.
Price Range : 971.00 USD - 4717.00 USD
Adenosine 5 Triphosphate 250 µCi

Quinuclidinyl Benzilate, L-[Benzilic-4,4`-3H]-, 250µCi (9.25MBq)

L-quinuclidinyl benzilate (QNB), tritiated at the benzilic-4,4' position. L-quinuclidinyl benzilate acts as an antagonist at muscarinic acetylcholine receptors.
List Price : 1396.00 USD

MK-912, [3H(G)]

MK-912 radioligand. MK-912 acts as a selective antagonist at the α2-adrenoceptor. This product has a scheduled lot release for the second Monday in October. NOTE: NET1227025UC will be obsoleted soon.
List Price : 2885.00 USD
Adenosine 5 Triphosphate 250 µCi

Pirenzepine, [N-Methyl-3H]

Pirenzepine, tritiated on the N-methyl group. Pirenzepine acts as a selective antagonist of the muscarinic M1 acetylcholine receptor.
Price Range : 1940.00 USD - 4909.00 USD
Adenosine 5 Triphosphate 250 µCi

Cyclopentyl-1,3-Dipropylxanthine, 8-[Dipropyl-2,3-3H(N)]

8-Cyclopentyl-1,3-dipropylxanthine (DPCPX, PD-116,948), tritiated at the dipropyl-2,3- positions. DPCPX acts as a potent and selective antagonist for the adenosine A1 receptor.
Price Range : 1300.00 USD - 2980.00 USD
Adenosine 5 Triphosphate 250 µCi

Dihydroxyphenylethylamine (Dopamine), 3,4-[Ring-2,5,6-3H]

Dihydroxyphenylethylamine (dopamine, DA), tritiated at the ring-2,5,6- position. Dihydroxyphenylethylamine is a neurotransmitter and is the primary endogenous ligand for dopamine receptors.
Price Range : 640.00 USD - 1485.00 USD
Adenosine 5 Triphosphate 250 µCi

Citalopram, [N-Methyl-3H]

Citalopram, tritiated at the N-methyl group. Citalopram is a selective serotonin reuptake inhibitor (SSRI) antidpressant drug, and has been shown to block the serotonin transporter (SERT, 5-HTT).
Price Range : 1108.00 USD - 2418.00 USD
Adenosine 5 Triphosphate 250 µCi

Taurine, [2,2,3H]

Taurine, tritiated at the 2,2 position. Taurine acts as an agonist at glycine receptors.
Price Range : 1182.00 USD - 3805.00 USD
Adenosine 5 Triphosphate 250 µCi

(+)-Pentazocine, [Ring-1,3-3H]

(+)-Pentazocine radioligand tritiated at the 1,3 position on the ring. Pentazocine is a synthetic opioid shown to bind sigma 1 receptor.
Price Range : 621.00 USD - 4846.00 USD
Adenosine 5 Triphosphate 250 µCi

RX 821002, [6,7-3H(N)]-

RX 821002, tritiated at the 6,7 position. RX 821002 acts as an antagonist at α2-adrenoceptors.
List Price : 2048.00 USD
Diclofenac sodium- Phenylacetic acid C14

Iodoantipyrine, 4-[N-Methyl-14C]

4-Iodoantipyrine, labeled with C-14 on the N-methyl group. Iodoantipyrine has been used to measure cerebral blood flow.
Price Range : 705.00 USD - 5800.00 USD
Adenosine 5 Triphosphate 250 µCi

Methylhistamine Dihydrochloride, N-α-[methyl-3H]-, 250µCi (9.25MBq)

(R)-α-methylhistamine dihydrochloride, tritiated on the methyl group. α-Methylhistamine is a histamine agonist selective for the histamine H3 receptor.
List Price : 1094.00 USD
Diclofenac sodium- Phenylacetic acid C14

COUMARIN, 7-ETHOXY, [3- 14C]-

50 µCi quantities of 7-ETHOXY-[3-14C]-Coumarin are available for your research.
List Price : 1943.00 USD
Adenosine 5 Triphosphate 250 µCi

Ifenprodil, [Phenyl-3H]-, 250µCi (9.25MBq)

Ifenprodil, tritiated on the phenyl group. Ifenprodil acts as an antagonist at the N-methyl-D-aspartate (NMDA) receptor.
List Price : 1990.00 USD
Adenosine 5 Triphosphate 250 µCi

5-Hydroxy tryptamine, [3H]

5-hydroxytryptamine (5-HT, or serotonin) labeled with tritium. It is a naturally occurring neurotransmitter which is tied to positive mood, certain involuntary muscle control, and countless other functions.
Price Range : 614.00 USD - 2254.00 USD
Adenosine 5 Triphosphate 250 µCi

CP 55940, [Side Chain-2,3,4-3H(N)]

CP 55,940, tritiated on the side chain-2,3-4 position. CP 55,940 is a synthetic cannabinoid that acts as a full agonist at both cannabinoid CB1 and CB2 receptors, and can also upregulate serotonin 5-HT2A receptors.
Price Range : 669.00 USD - 4915.00 USD
Adenosine 5 Triphosphate 250 µCi

CGP 39653, [Propyl-2,3,3H]

CGP 39653, tritiated at the propyl-2,3 position. CGP 39653 acts as an N-methyl-D-aspartate (NMDA) antagonist.
Price Range : 638.00 USD - 5500.00 USD
Adenosine 5 Triphosphate 250 µCi

Lysergic Acid Diethylamide, [N-Methyl-3H]-, 250µCi (9.25MBq)

Lysergic Acid Diethylamide (LSD), tritiated on the N-methyl group. LSD is a partial agonist of dopamine D2 receptors. It also binds most serotonin receptors (5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT5B and 5-HT6). This product has a scheduled lot release for the second Monday in April, August and December.
List Price : 1970.00 USD
Adenosine 5 Triphosphate 250 µCi

Chloramphenicol, [Ring-3,5-3H]

Chloramphenicol, tritiated at the ring-3,5 position. Chloramphenicol is a broad spectrum antibiotic that binds to a receptor site on the 50S subunit of the bacterial ribosome, inhibiting peptidyl transferase.
Price Range : 1884.00 USD - 4131.00 USD
Adenosine 5 Triphosphate 250 µCi

GR125743, [N-METHYL-3H]

GR125743, tritiated on the N-methyl group. GR125743 acts as an antagonist at serotonin 5-HT1B and 5-HT1D receptors.
List Price : 1810.00 USD
Adenosine 5 Triphosphate 250 µCi

Bradykinin, [2,3-Prolyl-3,4-3H(N)]

Bradykinin, tritiated at the 2,3-prolyl-3,4 position. Bradykinin is the endogenous ligand that activates bradykinin B1 and B2 receptors.
Price Range : 1759.00 USD - 4016.00 USD
Adenosine 5 Triphosphate 250 µCi

Norepinephrine, Levo-[7-3H]

Levo-Norepinephrine, tritiated at the 7 position. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET). This product has a scheduled lot release for the third Monday in July.
Price Range : 1195.00 USD - 9100.00 USD
Adenosine 5 Triphosphate 250 µCi

GBR 12935, [Propylene-2,3-3H]

GBR 12935, tritiated at the propylene-2,3 position. GBR 12935 is a piperazine derivative that acts as a selective dopamine reuptake inhbitor.
Price Range : 2133.00 USD - 6000.00 USD
Adenosine 5 Triphosphate 250 µCi

5-CT, [3H]

5-carboxyamidotryptamine (5-CT) labeled with tritium. 5-CT is a tryptamine derivative closely related to the neurotransmitter serotonin. 5-CT acts as a non-selective, high-affinity full agonist at the 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5A, and 5-HT7 serotonin receptors. It also binds the 5-HT2, 5-HT3, 5-HT6 serotonin receptors with lower affinity.
List Price : 1261.00 USD
Adenosine 5 Triphosphate 250 µCi

Oxytocin, [Tyrosyl-3,5-3H]-, 50µCi (1.85MBq)

Oxytocin, tritiated on the tyrosyl group. Oxytocin is a neurotransmitter that binds and activates oxytocin receptors.
List Price : 1287.00 USD
Adenosine 5 Triphosphate 250 µCi

Scopolamine Methyl Chloride, [N-methyl-3H]

Scopolamine methyl chloride, tritiated on the N-methyl group. Scopolamine acts as an antagonist at muscarinic acetylcholine receptors.
Price Range : 1512.00 USD - 3468.00 USD
Adenosine 5 Triphosphate 250 µCi

Nitrendipine, [5-Methyl-3H]-, 25µCi (925kBq)

Nitrendipine, tritiated on the 5-methyl group. Nitrendipine is a dihydropyridine calcium channel blocker.
List Price : 894.00 USD
Adenosine 5 Triphosphate 250 µCi

Dihydroxyphenylethylamine, 3,4-[7-3H]

Dihydroxyphenylethylamine (dopamine, DA), tritiated at the 7 position. Dihydroxyphenylethylamine is a neurotransmitter and is the primary endogenous ligand for dopamine receptors. This product has a scheduled lot release for the second Monday in April and October.
Price Range : 801.00 USD - 2247.00 USD
Adenosine 5 Triphosphate 250 µCi

Ryanodine, [9,21-3H(N)]-, 250µCi (9.25MBq)

Ryanodine, tritiated at the 9,21 position. Ryanodine is a natural ligand for the ryanodinen receptor.
List Price : 2295.00 USD
Adenosine 5 Triphosphate 250 µCi

TCP, [Piperdyl-3,4-3H(N)]

Tenocyclidine (TCP), tritiated at the piperdyl-3,4 position. TCP acts as an antagonist at N-methyl-D-aspartate receptor (NMDA receptors).
Price Range : 647.00 USD - 2360.00 USD

MESULERGINE, [N-METHYL-3H]-, 250 µCi

Mesulergine, tritiated on the N-methyl group. Mesulergine acts as an antagonist at serotonin 5-HT2A and 5-HT2C receptors, and as a partial agonist at dopamine receptors.
List Price : 1776.00 USD
Diclofenac sodium- Phenylacetic acid C14

Hydroxytryptamine Binoxalate (Serotonin Binoxalate), 5-[1-14C]

5-Hydroxytryptamine Binoxalate (Serotonin Binoxalate), labeled with C-14 at the 1-position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors. NEC855 replaces product NEC225, which was labeled at the 2-position.
Price Range : 763.00 USD - 3266.00 USD
Adenosine 5 Triphosphate 250 µCi

Flunitrazepam, [Methyl-3H]

Flunitrazepam (Rohypnol), tritiated on the methyl group. Flunitrazepam is a benzodiazepine and acts as an agonist at GABAA (γ-aminobutyric acid) receptors.
Price Range : 529.00 USD - 5300.00 USD
Diclofenac sodium- Phenylacetic acid C14

DICLOFENAC SODIUM[PHENYLACETIC ACID RING- U-14C]

Diclofenac sodium, labeled with C-14 on the phenylacetic acid ring. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that acts as an antagonist at peroxisome prolifeator-activated receptor gamma (PPAR-γ or PPARG).
List Price : 2343.00 USD
Adenosine 5 Triphosphate 250 µCi

4-DAMP, [N-Methyl-3H]-, 250µCi (9.25MBq)

4-DAMP (1,1-dimethyl-4-diphenylacetoxypiperidinium iodide) tritiated at the N-methyl position. 4-DAMP is a selective muscarinic acetylcholinenergic receptor M3 antagonist.
List Price : 2582.00 USD
Adenosine 5 Triphosphate 250 µCi

DOFETILIDE, [N-METHYL-3H], 100 µCi

Dofetilide, tritiated at the N-methyl position. Dofetilide is a selective potassium channel (hERG) blocker.
List Price : 1575.00 USD

"Ligands" 1-50 of 119 Products and Services

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