Library Prep Automation

Next Generation Sequencing (NGS) workflow automation is a proven and high value solution of PerkinElmer’s liquid handling workstations for more than 10 years. With a portfolio of dedicated workstations offering a choice of pipetting heads, gripper options and application accessories, we offer flexibility in throughput, capacity and dynamic volume range to meet any of your NGS needs.

We collaborate with the leading NGS library prep kit vendors to deliver vendor qualified, robust turn-key automation solutions for industry leading protocols today and in the future. With over 120 of the most frequently used library prep protocols currently programmed on our NGS workstations, you can have your lab’s library prep automated quickly.

  • Over 120 automated library prep protocols are available and include workflows for: DNA, RNA, target capture and metagenomics library preparation.
    • More library prep protocols are being developed as vendor’s release them. Please inquire for the latest list.
  • Avoid sample tracking errors and sample-to-sample variability.
  • Construct between 8 - 384 libraries/day.
  • Our expert applications team can assist you with support and training to get your NGS workflow running quickly and efficiently.


arrow Why do I want to automate my NGS library preparation?

Automating NGS library preparation reduces errors, wasted reagents, hands-on time, and cost while simultaneously increasing the throughput of your NGS workflows. Automated NGS library preparation also ensures precision and accuracy across all of your samples and avoid tracking errors.


arrow What do NGS library preparation workstations include?
  • Precise and accuracy with 96 or 384 simultaneous channel pipetting
  • Integrated gripper to move labware across the deck
  • Robotic arm to move tip boxes on and off the deck
  • Thermal Elements
  • On-deck thermocyclers
  • Magnetic Elements
  • Microplate shakers
  • Microplate barcode readers

For research use only. Not for use in diagnostic procedures.

Library preparation from FFPE low input samples
Library preparation from FFPE low input samples

Automated construction of up to 48 samples

Zephyr G3 NGS Workstation

The Zephyr G3 NGS liquid handling platform is a compact, easy-to-use system specifically designed for complete library prep automation or for the separation of pre- and post-PCR processes. It can handle up to 48 samples per day.

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NGS Library Preparation Protocols
NGS Library Preparation Protocols

Automated construction of up to 96 samples per day

Sciclone G3 NGSx and NGSx iQ Workstations

With more than 70 automated library prep methods available, the Sciclone G3 NGSx and NGSx iQ workstations will get you up and running samples in days rather than weeks.

The Sciclone G3 NGSx workstation includes:

  • High precision, 96-channel pipetting head
  • Integrated gripper to move labware around the deck
  • Temperature control to heat or cool down plates
  • Magnetic plates to facilitate magnetic extraction
  • Plate shaker to thoroughly mix samples
  • Below deck storage to store pipette tips
  • Tip chute to remove consumables from the deck

The Sciclone G3 NGSx iQ workstation includes all the features of the Sciclone G3 NGSx workstation and also includes:

  • Integrated on-deck thermal cycler, for fully automated PCR preparation
  • Twister® III robotic arm, to store and move tip boxes on and off deck
Sample Prep in Functional Genomics
Sample Prep in Functional Genomics

Automated construction of up to 384 samples per day

Sciclone G3 NGSx HT Workstations

With a precise 384 channel low volume pipetting head and reaction miniaturization technology, the Sciclone G3 NGS HT workstation will increase your throughput while decreasing the cost of your NGS library preparation workflows by allowing miniaturization of typical library prep kits

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Automated NGS Library Preparation Protocols

From DNA-Seq and RNA-Seq to exome and supplementary protocols, are liquid handling workstations have distinct utility in NGS library preparation workflows. If you do not see your particular workflow, our application team can precisely automate your workflow.
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  • Sciclone (1)
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  • Sciclone HT Front

    Sciclone G3 NGSx HT Workstation

    Designed for very high throughput NGS protocols, the Sciclone® G3 NGSx HT Workstation is equipped to process 384 samples at once and can precisely pipette liquids down to 500 nL. This enables higher throughput and reaction miniaturization which can drastically reduce reagent volumes and per-sample costs while simultaneously increasing the throughput of your NGS assays.
  • Sciclone iQ Front

    Sciclone® G3 NGSx iQ Workstation

    The Sciclone G3 NGSx iQ workstation is designed for full automation of PCR preparation and walk-away NGS library preparation. This workstation includes the Twister® III robotic arm to perform even the most complex library preparation workflows.
  • Sciclone-G3-NGSx-Workstation

    Sciclone® G3 NGSx Workstation

    The Sciclone® G3 NGSx workstation is a complete benchtop solution for the automated construction of up to or greater than 96 libraries per day.

    Next generation sequencing (NGS) technologies are enabling science at unprecedented rates. As the cost of sequencing declines, throughput continues to increase and the number of applications for which sequencing data can be used is expanding. The Sciclone® G3 NGSx liquid handling workstation was designed for high throughput, walkaway NGS sample preparation. The deck design and intuitive interface virtually eliminate cross contamination and user error. This liquid handler simplifies the construction of up to or greater than 96 libraries per day.

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