PerkinElmer

Iodinated Compounds

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Radiometric detection is considered the gold standard for many applications, from drug discovery and development to plant sciences. 125I labeled compounds are useful in both basic research and drug discovery where they are used as tracers in radioimmunoassays (RIA) and ligands in binding studies. 125I is particularly versatile as it emits both gamma and Auger electrons. This means that can be it counted either directly, without requiring scintillation, or by using a liquid scintillation counter. We offer a wide range of 125I labeled compounds as well as customized services to label your unique compound.

We also provide customized services to 131I labeled your compound of interest.

For Research and investigative use only.

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1-25 of 65 Products & Services

  • CGRP Human 125l

    Iodo-(-)-Cyanopindolol, [125I]

    Iodo-(-)-cyanopindolol, labeled with 125I. Cyanopindolol acts as an antagonist at β1 adrenergic receptors and serotonin 5-HT1A receptors.
    Price Range : 1450.00 USD - 6200.00 USD
  • CGRP Human 125l

    Thyroxine, ([125I]-T4), 5700 µCi/µg

    Thyroxine (T4) labeled with 125I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T4 detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
    Price Range : 1150.00 USD - 3377.00 USD
  • CGRP Human 125l

    Triiodothyronine, ([125I]-T3)

    Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
    Price Range : 948.00 USD - 3205.00 USD
  • CGRP Human 125l

    N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent

    Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.
    Price Range : 772.00 USD - 2065.00 USD
  • CGRP Human 125l

    Vasoactive Intestinal Polypeptide (human, porcine, rat), [125I]

    Vasoactive intestinal polypeptide (VIP), labeled with 125I. VIP binds vasoactive intestinal peptide receptors VPAC1 and VPAC2, a group of GPCRs that are potential drug targets for nervous and endocrine disorders and several types of cancer.
    Price Range : 1224.00 USD - 2984.00 USD
  • CGRP Human 125l

    Ω-Conotoxin GVIA, [125I] Tyr22

    Ω-Conotoxin GVIA (ω-Conotoxin GVIA), labeled with 125I on tyrosine residue 22. Omega conotoxin CVIA is a calcium channel blocker.
    Price Range : 797.00 USD - 3360.00 USD
  • CGRP Human 125l

    CGP 42112A, [125I]

    CGP 42112A, labeled with 125I. CGP 42112A acts as an agonist at angiotensin AT2 receptors.
    Price Range : 946.00 USD - 3485.00 USD
  • [125I]- Epidermal Growth Factor (human, rat)

    NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
    Price Range : 945.00 USD - 3857.00 USD
  • CGRP Human 125l

    Ornithine Vasotocin Analog, [125I]-OVTA)

    Ornithine Vasotocin Analog (OVTA), labeled with 125I. OVTA binds oxytocin receptors, a hormone receptor involved in pregnancy, milk production, stress, social memory, and bonding.
    Price Range : 1465.00 USD - 3418.00 USD
  • CGRP Human 125l

    Iodoaminopotentidine, [125I]

    NEX431 [125I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.
    Price Range : 1212.00 USD - 3024.00 USD
  • CGRP Human 125l

    Pancreatic Polypeptide (human), [125I]

    Human pancreatic polypeptide (PP), labeled with 125I. Pancreatic polypeptide acts as an agonist at Pancreatic polypeptide receptors (Neuropeptide Y receptors), a class of GPCRs involved in appetite, circadian rhythm, and anxiety.
    Price Range : 1288.00 USD - 4409.00 USD
  • CGRP Human 125l

    α-Bungarotoxin, [125I]-Tyr54

    α-bungarotoxin, labeled with 125I on tyrosine residue 54. α-bungarotoxin is a snake venom neurotoxin that acts as an antagonist at nicotinic acetylcholine receptors (nAChRs). This product as offered at two specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available). This indicates that virtually every molecule of ligand provided in the stock vial is radiolabeled.
    Price Range : 722.00 USD - 4153.00 USD
  • CGRP Human 125l

    LH-RH, [125I]-[D-Trp6]

    Luteinizing Hormone Releasing Hormone (LHRH), labeled with 125I. LHRH binds LHRH receptors, and is a drug target for cancer therapy.
    Price Range : 1343.00 USD - 4909.00 USD
  • CGRP Human 125l

    Ω-Conotoxin MVIIC, [125I]

    Ω-Conotoxin MVIIC (ω-Conotoxin MVIIC), labeled with 125I. Ω-Conotoxin MVIIC is a neurotoxin that blocks calcium channels.
    Price Range : 947.00 USD - 3619.00 USD
  • CGRP Human 125l

    Angiotensin II (human), [125I]-Tyr4, 50 μCi

    Angiotensin II (human), labeled with 125I on the tyrosine (Tyr4) residue. Angiotensin II binds and activates angiotensin II receptor type 1 (AT1) and type 2 (AT2) receptors, a class of GPCRs important in vasoconstriction. Angiotensin II is a potential drug target for blood pressure regulation.
    List Price : 4123.00 USD
  • CGRP Human 125l

    PDGF [125I] (human)

    NEX433 [125I]-PDGF BB homodimer has been shown to work in RIA and receptor studies, using CHO cell line transfected with human PDGF B receptor, and human artery smooth muscle cells.
    Price Range : 1462.00 USD - 5500.00 USD
  • CGRP Human 125l

    Cholecystokinin Octapeptide, [125I]-, Bolton-Hunter Labeled

    Cholecystokinin Octapeptide (CCK-8), labeled with 125I. Cholecystokinin is a neuropeptide that exists in several forms, identified by the number of amino acids in the peptide sequence. CCK8 contains 8 amino acids. The sulphated version of cholecystokinin can bind both Cholecystokinin A and Cholecystokinin B receptors. These receptors are involved in anxiety, feeding, and locomotion and are potential drug targets for depression and satiety.
    Price Range : 2621.00 USD - 12300.00 USD
  • CGRP Human 125l

    Insulin (human, recombinant), [125I]

    [125I]-Insulin (h) is suitable for the use in radioimmunoassay as well as receptor binding assay. [125I]-Insulin (h) is radioiodinated with no carrier added 125I using the LPO iodination procedure and is purified by reversed phase HPLC.
    Price Range : 1359.00 USD - 2693.00 USD
  • CGRP Human 125l

    MIP-1α (human, recombinant), [125I]

    Human recombinant macrophage inflammatory protein 1-alpha (MIP-1α; CCL3), labeled with 125I. MIP-1α is a cytokine involved in acute inflammation, and binds C-C chemokine receptors CCR1, CCR4, and CCR5.
    Price Range : 938.00 USD - 3843.00 USD
  • CGRP Human 125l

    IP-10 (human, recombinant), [125I]-, Bolton-Hunter Labeled

    Interferon gamma-induced protein 10 (IP-10; CXCL10), labeled with 125I. IP-10 binds the chemokine CXCR3 receptor, and is secreted in response to IFN-γ.
    Price Range : 1067.00 USD - 1992.00 USD
  • CGRP Human 125l

    Iodo-Melatonin, 2-[125I]

    Melatonin, labeled with 125I. Melatonin binds and activates melatonin receptors, a class of GPCRs that are potential drug targets for circadian rhythm sleep disorders and depression.
    Price Range : 1338.00 USD - 3185.00 USD
  • CGRP Human 125l

    RTI-55, [125I]

    RTI-55, labeled with 125I. RTI-55 is a nonselective dopamine reuptake inhibitor that is used to assess neuron degradation in Parkinson's disease and other neurodegenerative diseases.
    Price Range : 1153.00 USD - 4048.00 USD
  • CGRP Human 125l

    Vasopressin, [125I]Tyr2, Arg8

    Vasopressin, labeled with 125I on tyrosine residue 2. Vasopressin binds and activates vasopressin receptors, a group of GPCRs that are potential drug targets for hyponatremia, congestive heart failure, and cirrhosis.
    Price Range : 1163.00 USD - 2740.00 USD
  • CGRP Human 125l

    Orexin A, [125I]

    Orexin A, labeled with 125I. Orexin A binds to orexin receptors (OX1 and OX2), which are potential drug targets for sleep disorders.
    Price Range : 1456.00 USD - 4547.00 USD
  • CGRP Human 125l

    Gastric Inhibitory Polypeptide (human), [125I]

    Gastric inhibitor polypeptide (GIP), labeled with 125I. GIP is a hormone that binds receptors found on beta cells in the pancreas.
    Price Range : 1399.00 USD - 2491.00 USD
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