Inflammation Research

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Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

LANCE^® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
AlphaLISA^® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
DELFIA^® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
Cellular, tissue, and in vivo imaging systems
Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
High content screening

This product portfolio meets the demands of many types of inflammation research:

Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
Phenotypic analysis
Targeted studies in various sample types with high sensitivity and specificity

Products & Services (326)
Technical Resources (462)
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Products & Services (326)

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Product Type

Accessories (44)
Consumables (2)
Instruments (11)
Reagents (262)
Software and Informatics (7)

Assay Target

CCL1 (1)
CCL18 (1)
CCL2 (3)
CCL3 (3)
CCL4 (1)
CCL5 (3)
CCL8 (1)
CRP (1)
CXCL1 (2)
CXCL1/GROα (2)
CXCL10 (3)
CXCL13 (4)
CXCL4/PF4 (2)
CXCL9 (3)
Cyr61 (1)
Fibrinogen (2)
G-CSF (1)
GM-CSF (2)
HO-1 (2)
HO-2 (2)
HVEM (2)
IFN-λ2 (4)
IFNα (2)
IFNγ (10)
IL-1RA (4)
IL-23 (2)
IL-23A (2)
IL-31 (2)
IL-6 (3)
IL10 (2)
IL11 (2)
IL12 (7)
IL12/p70 (1)
IL13 (3)
IL15 (1)
IL17A (8)
IL17F (4)
IL18 (1)
IL18BP (2)
IL1α (4)
IL1β (7)
IL2 (4)
IL21 (2)
IL22 (1)
IL23 (1)
IL25 (4)
IL28B (4)
IL31 (1)
IL33 (4)
IL4 (6)
IL5 (4)
IL6 (7)
IL7 (1)
IL8 (3)
IP10 (2)
IRAK4 (1)
MCP2 (1)
MIP1α (2)
Osteoprotegerin (3)
PDGF (2)
Periostin (1)
TNFα (12)
TNRFR1 (1)
TNRFR3 (1)
TSLP (2)

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Bovine (6)
Cynomolgus (4)
Human (122)
Monkey (2)
Mouse (31)
Ovine (2)
Porcine (4)
Rat (1)

Application

cAMP (10)
Drug Discovery & Development (13)
High biotin samples (7)
Immunohistochemistry (IHC) (23)
In situ hybridization (ISH) (23)
In vivo imaging (1)
Protein Analysis & Detection (159)
Protein-protein interactions (2)

Therapeutic Area

Angiogenesis (13)
Arthritis (9)
Atherosclerosis (6)
Cancer (2)
Cardiovascular (9)
Central Nervous System (3)
Gastrointestinal (4)
Inflammation (215)
Metabolic (4)
Oncology/Cancer (9)
Pain (8)
Vascular disease (4)

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AequoScreen (11)
AequoZen (8)
AlphaLISA (126)
AlphaPlex (4)
Ancillary Products (2)
cAMPZen (8)
Cat B FAST (2)
FMT (3)
FolateRSense (1)
IVIS (6)
LANCE Ultra (44)
Membrane Target Systems (9)
MMPSense (1)
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Operetta (29)
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Operetta CLS AND Opera Phenix (9)
ProSense (1)
Superhance (1)
TSA (12)
TSA Plus (12)
ValiScreen (10)
VivoTrack (2)
XenoLight (2)

Detection Method

Alpha (131)
Chromogenic (6)
Fluorescence (27)
Time-Resolved Fluorescence (TRF) (24)
TR-FRET (24)
Transmission (2)

Receptor Type

Anaphylatoxin (1)
Bradykinin (4)
Chemokine (28)
Histamine (11)
Prostanoid (2)

Assay Validated

Binding (24)
Calcium Fluorescence (7)
Calcium Luminescence (19)
cAMP (16)
Downstream Phosphorylation (7)
GTPγS (9)
Inositol Phosphate (2)

Volume Capacity

150 µL (2)

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Activatable (5)
Cell labeling (2)
Targeted (1)
Vascular (4)

Fluorophore

Coumarin (1)
Cy3 (8)
Cy5 (4)
Fluorescein (6)
TMR (5)

Assay Points (200-50,000)

100 (51)
10000 (28)
500 (117)
5000 (88)

Assay Target Class

Cytokine (144)
GPCR (46)
Protein (24)

Automation Compatible

Yes (177)

Experimental Type

In vitro (126)

Format

Microplates (149)
Slides (23)

Host Cell

CHO-K1 (43)
HEK293 (3)

Imaging Modality

Chemilumiluminescence (2)
Fluorescence (11)
High Content (2)
microCT Imaging (1)
Optical Imaging (9)

Length

51-100 (1)
101-200 (1)

Model Compatible With

Operetta (30)
Operetta CLS (8)
Operetta CLS AND Opera Phenix (10)

1-25 of 326 Products & Services

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Opera Phenix High-Content Screening System

HH14000000

The Opera Phenix^™ High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera^® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
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IVIS Spectrum In Vivo Imaging System

124262

The IVIS^® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
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IVIS SpectrumCT In Vivo Imaging System

128201

The IVIS^® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
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IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

CLS137325

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
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FMT 4000 In Vivo Imaging System

FMT4000

The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
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FMT 1000 In Vivo Imaging System

FMT1000-750MSIM

The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
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FMT 2000 In Vivo Imaging System

FMT2000

The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
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Operetta CLS High-Content Analysis System

HH16000000

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS^™ high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS^™ lets you find even subtle phenotypic changes.
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IVIS Lumina III In Vivo Imaging System

CLS136334

The IVIS^® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
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IVIS Lumina XRMS In Vivo Imaging System

CLS136340

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS^® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
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IVIS Lumina LT In Vivo Imaging System

CLS136331

The IVIS^® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
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IL-4 (rhesus) AlphaLISA Detection Kit

AL564F , AL564C , AL564HV

The AlphaLISA^® immunoassay kit for rhesus interleukin-4 (IL-4) enables the quantitative determination of rhesus IL-4 in buffered solution, cell lysates, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 451.00 USD - 9900.00 USD
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IL-15 (human) AlphaLISA Biotin-Free Detection Kit

AL360C , AL360F , AL360HV

The AlphaLISA^® Human IL-15 Biotin-Free Detection Kit is designed for the quantitative detection of human Interleukin 15 in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.

Price Range : 465.00 USD - 10200.00 USD
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MCP2 (mouse) AlphaLISA Detection Kit

AL582HV , AL582C , AL582F

The AlphaLISA^® immunoassay kit for mouse MCP2 enables the quantitative determination of mouse monocyte chemoattractant protein 2 (MCP2; CCL8) in buffer and serum using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 1166.00 USD - 11100.00 USD
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ValiScreen Prostanoid EP2 (human) cell line

ES-562-C

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
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CXCL9/MIG (human) LANCE Ultra TR-FRET Detection Kit

TRF1280C , TRF1280M

The LANCE^® Ultra Human CXCL9/MIG Detection Kit is designed for detection and quantitation of human CXCL9/MIG in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 830.00 USD - 11100.00 USD
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IL-1RA (human) LANCE Ultra TR-FRET Detection Kit

TRF1358C , TRF1358M

The LANCE® Ultra Human IL-1RA Detection Kit is designed for detection and quantitation of human interleukin-1RA in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 930.00 USD - 12400.00 USD
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TSA Cy 3, Cy 5, TMR, Fluorescein Evaluation Kit

NEL760001KT

TSA^® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.

List Price : 455.00 USD
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IL-28B (human), lyophilized (AlphaLISA)

AL365S

Human IL-28B standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human IL-28B Detection Kit, but can be ordered separately.

List Price : 250.00 USD
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Chemokine CCR1, Human Recombinant, CHO-K1 cAMPZen Frozen cells

ES-132-CF

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.

List Price : 636.00 USD
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IL-5 (mouse) AlphaLISA Detection Kit

AL569F , AL569HV , AL569C

The AlphaLISA^® immunoassay kit for mouse IL-5 enables the quantitative determination of mouse interleukin-5 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 625.00 USD - 15000.00 USD
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IL-13 (mouse), lyophilized (AlphaLISA)

AL565S

Mouse IL-13 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA mouse IL-13 Detection Kit, but can also be ordered separately.

List Price : 308.00 USD
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IL-6 (mouse) AlphaLISA Detection Kit

AL504F , AL504C

The AlphaLISA^® Mouse Interleukin-6 (IL-6) Detection Kit is designed for detection and quantitation of mouse IL-6 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The kit is a superior alternative to a traditional mouse IL-6 ELISA kit due to its simple and fast protocol, wide dynamic range, and high sensitivity.

Price Range : 1585.00 USD - 10500.00 USD
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Membrane Target Systems: Histamine H2 (human) membrane preparation, in HEK-293 cells. 400 Units.

6110565400UA

Cell membranes prepared from HEK293 cells stably transfected with human Histamine H2 receptor, 400 units.

List Price : 982.00 USD
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CCL5 (human) LANCE Ultra TR-FRET Detection Kit

TRF1289M , TRF1289C

The LANCE^® Ultra Human CCL5/RANTES Detection Kit is designed for detection and quantitation of human CCL5 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 830.00 USD - 11100.00 USD