PerkinElmer

Inflammation Research

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Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

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1-25 of 305 Products & Services

  • FMT In Vivo Imaging Instrument
    Quick View

    FMT 1000 In Vivo Imaging System

    FMT1000-750MSIM
    The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray
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    IVIS Lumina XRMS In Vivo Imaging System

    CLS136340
    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • Opera Phenix High-Content Screening System
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    Opera Phenix High-Content Screening System

    HH14000000
    The Opera Phenix™ High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
  • SpectrumBL-CU-Hero
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    IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

    CLS137325
    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • Spectrum-CU-Hero
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    IVIS Spectrum In Vivo Imaging System

    124262
    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • IVIS-SpectrumCT-Hero
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    IVIS SpectrumCT In Vivo Imaging System

    128201
    The IVIS® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System
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    IVIS Lumina LT In Vivo Imaging System

    CLS136331
    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System
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    IVIS Lumina III In Vivo Imaging System

    CLS136334
    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • Operetta CLS High-Content Analysis System
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    Operetta CLS High-Content Analysis System

    HH16000000
    Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS™ high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS™ lets you find even subtle phenotypic changes.
  • FMT In Vivo Imaging Instrument
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    FMT 4000 In Vivo Imaging System

    FMT4000
    The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
  • FMT In Vivo Imaging Instrument
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    FMT 2000 In Vivo Imaging System

    FMT2000
    The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
  • AlphaLISA immunoassay kits
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    IL-12 (bovine) AlphaLISA Detection Kit

    AL553HV , AL553C , AL553F
    The AlphaLISA® immunoassay kit for bovine IL-12 enables the quantitative determination of bovine IL-12 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 652.00 USD - 19600.00 USD
  • AlphaPlex Terbium immunoassay kits
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    AlphaPlex-545 Human IL1β Detection Kit

    AP220TB-HV , AP220TB-C , AP220TB-F
    The AlphaPlex™ 545 Human IL1β Detection Kit is designed for the quantitative determination of human IL1β together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous assay.
    Price Range : 700.00 USD - 12000.00 USD
  • AlphaLISA immunoassay kits
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    IL-4 (human) AlphaLISA Detection Kit

    AL266C , AL266F
    The AlphaLISA® Human Interleukin 4 (IL4) Detection Kit is designed for detection and quantitation of human IL4 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1811.00 USD - 12600.00 USD
  • Protein
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    IL-28B (human), lyophilized (LANCE)

    TRF1365S
    Human IL-28B standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human IL-28B Detection Kit, but can also be ordered separately.
    List Price : 292.00 USD
  • LANCE Detection Kit
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    IL-31 (human) LANCE Ultra TR-FRET Detection Kit

    TRF3003C , TRF3003M
    The LANCE® Ultra Human IL-31 Detection Kit is designed for detection and quantitation of human interleukin-31 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 840.00 USD - 11200.00 USD
  • AlphaLISA immunoassay kits
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    IL-15 (human) AlphaLISA Biotin-Free Detection Kit

    AL360HV , AL360C , AL360F
    The AlphaLISA® Human IL-15 Biotin-Free Detection Kit is designed for the quantitative detection of human Interleukin 15 in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.
    Price Range : 531.00 USD - 11600.00 USD
  • AlphaLISA immunoassay kits
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    IL-4 (rhesus) AlphaLISA Detection Kit

    AL564HV , AL564C , AL564F
    The AlphaLISA® immunoassay kit for rhesus interleukin-4 (IL-4) enables the quantitative determination of rhesus IL-4 in buffered solution, cell lysates, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 515.00 USD - 11300.00 USD
  • AlphaLisa Analyte 2
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    IL-25 (human), liquid (AlphaLISA)

    AL3048S
    Human interleukin 25 (IL-25) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human IL-25 Detection Kit, but can also be ordered separately.
    List Price : 352.00 USD
  • AlphaLisa Analyte 2
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    IL-31 (human), lyophilized (LANCE)

    TRF3003S
    Human IL-31 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human IL-31 TR-FRET Detection Kit, but can also be ordered separately.
    List Price : 253.00 USD
  • AlphaLISA immunoassay kits
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    CXCL4/PF4 (Human) AlphaLISA Detection Kit

    AL398HV , AL398C , AL398F
    The AlphaLISA® immunoassay kit for CXCL4/PF4 enables the quantitative determination of CXCL4/PF4 in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows minumum cross-reactivity with mouse CXCL4/PF4 and human CXCL4L1/PF4V.
    Price Range : 736.00 USD - 22100.00 USD
  • In vivo Fluorescent Agents
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    MMPSense Fluorescent Imaging Agent

    NEV10126 , NEV10100 , NEV10168

    Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

    PerkinElmer’s MMPSense NIR activatable fluorescence agents are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

    List Price : 753.00 USD
  • alphaimmunoassay1
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    IL-1β (human) AlphaLISA Detection Kit

    AL220C , AL220F
    The AlphaLISA® Human Interleukin-1β (IL1β) Detection Kit is designed for detection and quantitation of human IL-1β in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1811.00 USD - 12000.00 USD
  • AlphaLISA immunoassay kits
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    CXCL13 (human) AlphaLISA Detection Kit

    AL3098HV , AL3098C , AL3098F
    The AlphaLISA® immunoassay kit for human CXCL13 enables the quantitative determination of human C-X-C Motif Chemokine Ligand 13 in serum and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 893.00 USD - 12800.00 USD
  • Receptor-expressing cell lines
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    ValiScreen Histamine H1 (human) cell line

    ES-390-C
    Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
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