PerkinElmer

Inflammation Research

OF

Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

Products & Services (326)
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Product Type
  • Accessories (44)
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  • Instruments (11)
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Assay Target
  • CCL1 (1)
  • CCL18 (1)
  • CCL2 (3)
  • CCL3 (3)
  • CCL4 (1)
  • CCL5 (3)
  • CCL8 (1)
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  • CXCL1 (2)
  • CXCL1/GROα (2)
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  • IFN-λ2 (4)
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  • IL-6 (3)
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Target Species
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  • Human (122)
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Application
  • cAMP (10)
  • Drug Discovery & Development (13)
  • High biotin samples (7)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • In vivo imaging (1)
  • Protein Analysis & Detection (159)
  • Protein-protein interactions (2)
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  • Gastrointestinal (4)
  • Inflammation (215)
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  • Pain (8)
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  • AequoScreen (11)
  • AequoZen (8)
  • AlphaLISA (126)
  • AlphaPlex (4)
  • Ancillary Products (2)
  • cAMPZen (8)
  • Cat B FAST (2)
  • FMT (3)
  • FolateRSense (1)
  • IVIS (6)
  • LANCE Ultra (44)
  • Membrane Target Systems (9)
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  • Operetta (29)
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  • Operetta CLS AND Opera Phenix (9)
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Detection Method
  • Alpha (131)
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  • Time-Resolved Fluorescence (TRF) (24)
  • TR-FRET (24)
  • Transmission (2)
Receptor Type
  • Anaphylatoxin (1)
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Assay Validated
  • Binding (24)
  • Calcium Fluorescence (7)
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  • Downstream Phosphorylation (7)
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Volume Capacity
  • 150 µL (2)
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  • Activatable (5)
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Fluorophore
  • Coumarin (1)
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Assay Points (200-50,000)
  • 100 (51)
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  • 5000 (88)
Assay Target Class
  • Cytokine (144)
  • GPCR (46)
  • Protein (24)
Automation Compatible
  • Yes (177)
Experimental Type
  • In vitro (126)
Format
  • Microplates (149)
  • Slides (23)
Host Cell
  • CHO-K1 (43)
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Imaging Modality
  • Chemilumiluminescence (2)
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  • microCT Imaging (1)
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Length
  • 51-100 (1)
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Model Compatible With
  • Operetta (30)
  • Operetta CLS (8)
  • Operetta CLS AND Opera Phenix (10)

1-25 of 326 Products & Services

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  • 1000x1000_Opera_Phenix

    Opera Phenix High-Content Screening System

    The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
  • Spectrum-CU-Hero

    IVIS Spectrum In Vivo Imaging System

    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • IVIS-SpectrumCT-Hero

    IVIS SpectrumCT In Vivo Imaging System

    The IVIS® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • SpectrumBL-CU-Hero

    IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • FMT In Vivo Imaging Instrument

    FMT 4000 In Vivo Imaging System

    The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
  • FMT In Vivo Imaging Instrument

    FMT 1000 In Vivo Imaging System

    The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
  • FMT In Vivo Imaging Instrument

    FMT 2000 In Vivo Imaging System

    The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
  • 1000x1000_Operetta

    Operetta CLS High-Content Analysis System

    Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS Lumina III In Vivo Imaging System

    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS In Vivo Imaging System

    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS Lumina LT In Vivo Imaging System

    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • IL-4 (rhesus) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for rhesus interleukin-4 (IL-4) enables the quantitative determination of rhesus IL-4 in buffered solution, cell lysates, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 451.00 USD - 9900.00 USD
  • AlphaLISA immunoassay kits

    IL-15 (human) AlphaLISA Biotin-Free Detection Kit

    The AlphaLISA® Human IL-15 Biotin-Free Detection Kit is designed for the quantitative detection of human Interleukin 15 in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.
    Price Range : 465.00 USD - 10200.00 USD
  • AlphaLISA immunoassay kits

    MCP2 (mouse) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for mouse MCP2 enables the quantitative determination of mouse monocyte chemoattractant protein 2 (MCP2; CCL8) in buffer and serum using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 1166.00 USD - 11100.00 USD
  • Receptor-expressing cell lines

    ValiScreen Prostanoid EP2 (human) cell line

    Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
  • LANCE Detection Kit

    CXCL9/MIG (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human CXCL9/MIG Detection Kit is designed for detection and quantitation of human CXCL9/MIG in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 830.00 USD - 11100.00 USD
  • LANCE Detection Kit

    IL-1RA (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human IL-1RA Detection Kit is designed for detection and quantitation of human interleukin-1RA in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 930.00 USD - 12400.00 USD
  • TSA Cyanine 3 & 5, TMR, Fluorescein Evaluation Kit

    TSA Cy 3, Cy 5, TMR, Fluorescein Evaluation Kit

    TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
    List Price : 455.00 USD
  • AlphaLisa Analyte 2

    IL-28B (human), lyophilized (AlphaLISA)

    Human IL-28B standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human IL-28B Detection Kit, but can be ordered separately.
    List Price : 250.00 USD
  • Receptor-expressing cell lines

    Chemokine CCR1, Human Recombinant, CHO-K1 cAMPZen Frozen cells

    Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
    List Price : 636.00 USD
  • IL-5 (mouse) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for mouse IL-5 enables the quantitative determination of mouse interleukin-5 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 625.00 USD - 15000.00 USD
  • AlphaLisa Analyte 2

    IL-13 (mouse), lyophilized (AlphaLISA)

    Mouse IL-13 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA mouse IL-13 Detection Kit, but can also be ordered separately.
    List Price : 308.00 USD
  • IL-6 (mouse) AlphaLISA Detection Kit

    The AlphaLISA® Mouse Interleukin-6 (IL-6) Detection Kit is designed for detection and quantitation of mouse IL-6 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The kit is a superior alternative to a traditional mouse IL-6 ELISA kit due to its simple and fast protocol, wide dynamic range, and high sensitivity.
    Price Range : 1585.00 USD - 10500.00 USD
  • Membrane Target Systems

    Membrane Target Systems: Histamine H2 (human) membrane preparation, in HEK-293 cells. 400 Units.

    Cell membranes prepared from HEK293 cells stably transfected with human Histamine H2 receptor, 400 units.
    List Price : 982.00 USD
  • CCL5 (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human CCL5/RANTES Detection Kit is designed for detection and quantitation of human CCL5 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 830.00 USD - 11100.00 USD
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