Inflammation Research

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Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

LANCE^® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
AlphaLISA^® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
DELFIA^® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
Cellular, tissue, and in vivo imaging systems
Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
High content screening

This product portfolio meets the demands of many types of inflammation research:

Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
Phenotypic analysis
Targeted studies in various sample types with high sensitivity and specificity

Products & Services (295)
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Business Insights (17)

Products & Services (295)

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Accessories (43)
Consumables (2)
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Assay Target

CCL1 (1)
CCL18 (1)
CCL2 (3)
CCL3 (3)
CCL4 (1)
CCL5 (3)
CCL8 (1)
CRP (1)
CXCL1 (2)
CXCL1/GROα (2)
CXCL10 (3)
CXCL13 (4)
CXCL4/PF4 (2)
CXCL9 (3)
Cyr61 (1)
Fibrinogen (2)
G-CSF (1)
GM-CSF (2)
HO-1 (2)
HO-2 (2)
HVEM (2)
IFN-λ2 (4)
IFNα (2)
IFNγ (10)
IL-1RA (4)
IL-23 (2)
IL-23A (2)
IL-31 (2)
IL-6 (3)
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IL12/p70 (1)
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cAMP (10)
Drug Discovery & Development (13)
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Protein Analysis & Detection (158)
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Therapeutic Area

Angiogenesis (13)
Arthritis (9)
Atherosclerosis (6)
Cancer (2)
Cardiovascular (9)
Central Nervous System (3)
Gastrointestinal (4)
Inflammation (214)
Metabolic (4)
Oncology/Cancer (9)
Pain (8)
Vascular disease (4)

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AequoScreen (11)
AequoZen (8)
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Anaphylatoxin (1)
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Binding (24)
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Activatable (5)
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Cytokine (144)
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Automation Compatible

Yes (176)

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In vitro (125)

Format

Microplates (148)

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CHO-K1 (43)
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Chemilumiluminescence (2)
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microCT Imaging (1)
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Length

51-100 (1)
101-200 (1)

Model Compatible With

Operetta (29)
Operetta CLS (8)
Operetta CLS AND Opera Phenix (10)

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1-25 of 295 Products & Services

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IVIS Lumina XRMS In Vivo Imaging System

CLS136340

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS^® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
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Opera Phenix High-Content Screening System

HH14000000

The Opera Phenix^™ High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera^® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
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IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

CLS137325

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
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IVIS SpectrumCT In Vivo Imaging System

128201

The IVIS^® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
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IVIS Lumina III In Vivo Imaging System

CLS136334

The IVIS^® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
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IVIS Lumina LT In Vivo Imaging System

CLS136331

The IVIS^® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
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Operetta CLS High-Content Analysis System

HH16000000

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS^™ high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS^™ lets you find even subtle phenotypic changes.
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FMT 4000 In Vivo Imaging System

FMT4000

The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
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FMT 1000 In Vivo Imaging System

FMT1000-750MSIM

The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
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IVIS Spectrum In Vivo Imaging System

124262

The IVIS^® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
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FMT 2000 In Vivo Imaging System

FMT2000

The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
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IL-4 (rhesus) AlphaLISA Detection Kit

AL564HV , AL564C , AL564F

The AlphaLISA^® immunoassay kit for rhesus interleukin-4 (IL-4) enables the quantitative determination of rhesus IL-4 in buffered solution, cell lysates, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 515.00 USD - 11300.00 USD
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IL-1α (bovine) AlphaLISA Detection Kit

AL537HV , AL537F , AL537C

The AlphaLISA immunoassay kit for detection and quantitation of bovine IL1α in serum, cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.

Price Range : 768.00 USD - 12300.00 USD
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Periostin (human) AlphaLISA Detection Kit

AL3105HV , AL3105C , AL3105F

The AlphaLISA^® immunoassay kit for human periostin enables the quantitative determination of human periostin in buffer, cell culture media, and serum using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 893.00 USD - 12600.00 USD
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IL-28B (human), lyophilized (AlphaLISA)

AL365S

Human IL-28B standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human IL-28B Detection Kit, but can be ordered separately.

List Price : 286.00 USD
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IL-2 (mouse) AlphaLISA Detection Kit

AL511C , AL511F

The AlphaLISA^® Mouse Interleukin-2 (IL-2) Detection Kit is designed for detection and quantitation of mouse IL-2 in serum, buffered solution, or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 1811.00 USD - 12000.00 USD
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AequoZen FroZen cells, Histamin H₂, Human Recombinant, CHO-K1

ES-391-AF

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.

List Price : 1040.00 USD
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TNFα (human) AlphaLISA Biotin-Free Detection Kit

AL325F , AL325C , AL325HV

The AlphaLISA Human TNFα Biotin-Free Detection Kit is designed for the quantitative detection of human TNFα in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).

Price Range : 828.00 USD - 12000.00 USD
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TNFα (cynomolgus) AlphaLISA Detection Kit

AL562HV , AL562C , AL562F

The AlphaLISA^® Cynomolgus TNFα Detection Kit is designed for detection and quantitation of cynomolgus and rhesus monkey tumor necrosis factor alpha in cell culture media using a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 515.00 USD - 11300.00 USD
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Bradykinin rB1AequoScreen cell line

ES-092-A

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
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IL-1α (bovine), lyophilized (AlphaLISA)

AL537S

The AlphaLISA immunoassay kit for detection and quantitation of bovine IL1α in serum, cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.

List Price : 399.00 USD
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IL-1β (human) AlphaLISA Detection Kit

AL220F , AL220C

The AlphaLISA^® Human Interleukin-1β (IL1β) Detection Kit is designed for detection and quantitation of human IL-1β in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 1811.00 USD - 12000.00 USD
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Bradykinin B1 AequoScreen cell line

ES-091-A

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
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CCL3/MIP1α (human) LANCE Ultra TR-FRET Detection Kit

TRF1257M , TRF1257C

The LANCE^® Ultra Human CCL3/MIP1α Detection Kit is designed for detection and quantitation of human CCL3 (MIP1α) in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 865.00 USD - 11500.00 USD
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IL-1RA (human) AlphaLISA Detection Kit

AL358HV , AL358C , AL358F

The AlphaLISA^® Human IL-1RA Detection Kit is designed for detection and quantitation of human interleukin-1RA in cell culture media or serum using a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 531.00 USD - 11600.00 USD