Inflammation Research

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Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

LANCE^® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
AlphaLISA^® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
DELFIA^® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
Cellular, tissue, and in vivo imaging systems
Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
High content screening

This product portfolio meets the demands of many types of inflammation research:

Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
Phenotypic analysis
Targeted studies in various sample types with high sensitivity and specificity

Products & Services (299)
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Products & Services (299)

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Accessories (43)
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Assay Target

CCL1 (1)
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CCL2 (3)
CCL3 (3)
CCL4 (1)
CCL5 (3)
CCL8 (1)
CRP (1)
CXCL1 (2)
CXCL1/GROα (2)
CXCL10 (3)
CXCL13 (4)
CXCL4/PF4 (2)
CXCL9 (3)
Cyr61 (1)
Fibrinogen (2)
G-CSF (1)
GM-CSF (2)
HO-1 (2)
HO-2 (2)
HVEM (2)
IFN-λ2 (4)
IFNα (2)
IFNγ (10)
IL-1RA (4)
IL-23 (2)
IL-23A (2)
IL-31 (2)
IL-6 (3)
IL10 (2)
IL11 (2)
IL12 (7)
IL12/p70 (1)
IL13 (3)
IL15 (1)
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IL22 (1)
IL23 (1)
IL25 (4)
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IL33 (4)
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IL8 (3)
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MCP2 (1)
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cAMP (10)
Drug Discovery & Development (13)
High biotin samples (7)
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Protein Analysis & Detection (159)
Protein-protein interactions (2)

Therapeutic Area

Angiogenesis (13)
Arthritis (9)
Atherosclerosis (6)
Cancer (2)
Cardiovascular (9)
Central Nervous System (3)
Gastrointestinal (4)
Inflammation (215)
Metabolic (4)
Oncology/Cancer (9)
Pain (8)
Vascular disease (4)

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AequoScreen (11)
AequoZen (8)
AlphaLISA (126)
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Ancillary Products (2)
cAMPZen (8)
Cat B FAST (2)
FMT (3)
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Operetta CLS AND Opera Phenix (9)
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Binding (24)
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Inositol Phosphate (2)

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150 µL (2)

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Activatable (5)
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Targeted (1)
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Assay Points (200-50,000)

100 (51)
10000 (28)
500 (117)
5000 (88)

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Cytokine (144)
GPCR (46)
Protein (24)

Automation Compatible

Yes (177)

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In vitro (126)

Format

Microplates (149)

Host Cell

CHO-K1 (43)
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Chemilumiluminescence (2)
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High Content (2)
microCT Imaging (1)
Optical Imaging (9)

Length

51-100 (1)
101-200 (1)

Model Compatible With

Operetta (29)
Operetta CLS (8)
Operetta CLS AND Opera Phenix (10)

1-25 of 299 Products & Services

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IVIS Spectrum In Vivo Imaging System

124262

The IVIS^® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
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Operetta CLS High-Content Analysis System

HH16000000

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS^™ high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS^™ lets you find even subtle phenotypic changes.
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IVIS Lumina XRMS In Vivo Imaging System

CLS136340

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS^® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
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IVIS Lumina LT In Vivo Imaging System

CLS136331

The IVIS^® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
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IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

CLS137325

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
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FMT 1000 In Vivo Imaging System

FMT1000-750MSIM

The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
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FMT 2000 In Vivo Imaging System

FMT2000

The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
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IVIS Lumina III In Vivo Imaging System

CLS136334

The IVIS^® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
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FMT 4000 In Vivo Imaging System

FMT4000

The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
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Opera Phenix High-Content Screening System

HH14000000

The Opera Phenix^™ High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera^® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
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IVIS SpectrumCT In Vivo Imaging System

128201

The IVIS^® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
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IL-33 (human) AlphaLISA Detection Kit

AL3042C , AL3042HV , AL3042F

The AlphaLISA^® immunoassay kit for human IL-33 enables the quantitative determination of human interleukin-33 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 625.00 USD - 15000.00 USD
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IL-7 (human) AlphaLISA Detection Kit

AL268F , AL268C

The AlphaLISA^® Human Interleukin 7 (IL7) Detection Kit is designed for detection and quantitation of human IL-7 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 1585.00 USD - 10500.00 USD
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MMPSense Fluorescent Imaging Agent

NEV10100 , NEV10168 , NEV10126

Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

PerkinElmer’s MMPSense NIR activatable fluorescence agents are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

List Price : 731.00 USD
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cAMPZen Frozen cells, Chemokine CCR7, Human Recombinant, CHO-K1

ES-140-CF

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.

List Price : 636.00 USD
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IL-12/IL-23 (human), lyophilized (AlphaLISA)

AL382S

Human IL-12 standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Bovine IL-17A Detection Kit, but can be ordered separately.

List Price : 443.00 USD
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VivoTrack 680 NIR Fluorescent Imaging Agent (Explorer kit)

NEV12001

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.

List Price : 108.00 USD
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IL-1β (human) LANCE Ultra TR-FRET Detection Kit

TRF1220M , TRF1220C

The LANCE^® Ultra Human IL-1β Detection Kit is designed for detection and quantitation of human interleuukin-1β in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Price Range : 830.00 USD - 11000.00 USD
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Heme oxygenase 2, liquid (AlphaLISA)

AL3027S

Human heme oxygenase 2 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human HO-2 Detection Kit, but can also be ordered separately.

List Price : 243.00 USD
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IL-12 (bovine), lyophilized (AlphaLISA)

AL553S

Bovine IL-12 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA bovine IL-12 Detection Kit, but can also be ordered separately.

List Price : 308.00 USD
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CXCL4/PF4 (Human) AlphaLISA Detection Kit

AL398HV , AL398C , AL398F

The AlphaLISA^® immunoassay kit for CXCL4/PF4 enables the quantitative determination of CXCL4/PF4 in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows minumum cross-reactivity with mouse CXCL4/PF4 and human CXCL4L1/PF4V.

Price Range : 644.00 USD - 19300.00 USD
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Heme oxygenase 1 AlphaLISA Detection Kit

AL3026F , AL3026HV , AL3026C

The AlphaLISA^® immunoassay kit for human heme oxygenase 1 (HO-1) enables the quantitative determination of human HO-1 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 451.00 USD - 9900.00 USD
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IL-4 (rhesus), lyophilized (AlphaLISA)

AL564S

Rhesus IL-4 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA rhesus IL-4 Detection Kit, but can also be ordered separately.

List Price : 243.00 USD
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IL-12 (porcine) AlphaLISA Detection Kit

AL554F , AL554C , AL554HV

The AlphaLISA^® immunoassay kit for porcine IL-12 enables the quantitative determination of porcine interleukin-12 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 625.00 USD - 18800.00 USD
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IL-18 (human) AlphaLISA Detection Kit

AL241C , AL241F

The AlphaLISA^® Human Interleukin 18 (IL-18) Detection Kit is designed for detection and quantitation of human IL-18 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 1585.00 USD - 10500.00 USD