PerkinElmer

Inflammation Research

OF

Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

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Product Type
  • Accessories (44)
  • Consumables (2)
  • Instruments (11)
  • Reagents (268)
  • Software and Informatics (7)
Assay Target
  • CCL1 (1)
  • CCL18 (1)
  • CCL2 (3)
  • CCL3 (3)
  • CCL4 (1)
  • CCL5 (3)
  • CCL8 (1)
  • CRP (1)
  • CXCL1 (2)
  • CXCL1/GROα (2)
  • CXCL10 (3)
  • CXCL12 (2)
  • CXCL13 (4)
  • CXCL4/PF4 (2)
  • CXCL9 (3)
  • Cyr61 (1)
  • Fibrinogen (2)
  • G-CSF (1)
  • GM-CSF (2)
  • HO-1 (2)
  • HO-2 (2)
  • HVEM (2)
  • IFN-λ2 (4)
  • IFNα (2)
  • IFNγ (10)
  • IL-1RA (4)
  • IL-23 (2)
  • IL-23A (2)
  • IL-31 (2)
  • IL-6 (3)
  • IL10 (2)
  • IL11 (2)
  • IL12 (8)
  • IL13 (3)
  • IL15 (1)
  • IL17A (8)
  • IL17F (4)
  • IL18 (1)
  • IL18BP (2)
  • IL1α (4)
  • IL1β (7)
  • IL2 (4)
  • IL21 (2)
  • IL22 (1)
  • IL23 (1)
  • IL25 (4)
  • IL28B (4)
  • IL31 (1)
  • IL33 (4)
  • IL4 (6)
  • IL5 (4)
  • IL6 (7)
  • IL7 (1)
  • IL8 (3)
  • IP10 (2)
  • MCP2 (1)
  • MIP1α (2)
  • Osteoprotegerin (3)
  • PDGF (2)
  • Periostin (1)
  • SDF1 (2)
  • TNFα (10)
  • TSLP (4)
Target Species
  • Bovine (6)
  • Cynomolgus (4)
  • Human (123)
  • Monkey (2)
  • Mouse (33)
  • Ovine (2)
  • Porcine (4)
  • Rat (1)
Application
  • cAMP (10)
  • Drug Discovery & Development (13)
  • High biotin samples (7)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • In vivo imaging (1)
  • Protein Analysis & Detection (164)
Therapeutic Area
  • Angiogenesis (14)
  • Arthritis (13)
  • Atherosclerosis (9)
  • Cancer (2)
  • Cardiovascular (9)
  • Central Nervous System (3)
  • Gastrointestinal (4)
  • Inflammation (221)
  • Metabolic (4)
  • Oncology/Cancer (13)
  • Pain (8)
  • Vascular disease (5)
Product Brand Name
  • AequoScreen (11)
  • AequoZen (8)
  • AlphaLISA (127)
  • AlphaPlex (4)
  • Ancillary Products (2)
  • cAMPZen (8)
  • Cat B FAST (2)
  • FMT (3)
  • FolateRSense (1)
  • IVIS (6)
  • LANCE Ultra (44)
  • Membrane Target Systems (9)
  • MMPSense (3)
  • Opera Phenix (8)
  • Operetta (29)
  • Operetta CLS (1)
  • ProSense (3)
  • Superhance (1)
  • TSA (12)
  • TSA Plus (12)
  • ValiScreen (10)
  • VivoTrack (2)
  • XenoLight (2)
Detection Method
  • Alpha (132)
  • Chromogenic (6)
  • Fluorescence (27)
  • Time-Resolved Fluorescence (TRF) (24)
  • TR-FRET (24)
  • Transmission (2)
Receptor Type
  • Anaphylatoxin (1)
  • Bradykinin (4)
  • Chemokine (28)
  • Histamine (11)
  • Prostanoid (2)
Assay Validated
  • Binding (24)
  • Calcium Fluorescence (7)
  • Calcium Luminescence (19)
  • cAMP (16)
  • Downstream Phosphorylation (7)
  • GTPγS (9)
  • Inositol Phosphate (2)
Volume Capacity
  • 150 µL (2)
Fluorescent Agent Type
  • Activatable (9)
  • Cell labeling (2)
  • Targeted (1)
  • Vascular (5)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy5 (4)
  • Fluorescein (6)
  • TMR (5)
Assay points(200-50,000)
  • 100 (51)
  • 10000 (28)
  • 500 (116)
  • 5000 (86)
Assay Target Class
  • Cytokine (146)
  • GPCR (46)
  • Protein (21)
Automation Compatible
  • Yes (178)
Experimental Type
  • In vitro (129)
Format
  • Microplates (152)
  • Slides (23)
Host Cell
  • CHO-K1 (43)
  • HEK293 (3)
Imaging Modality
  • Chemilumiluminescence (2)
  • Fluorescence (16)
  • High Content (2)
  • microCT Imaging (1)
  • Optical Imaging (9)
Length
  • 41-50 (3)
  • 51-100 (6)
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"Inflammation" 1-50 of 332 Products and Services

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FMT In Vivo Imaging Instrument

FMT 2000 In Vivo Imaging System

The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
IVIS Spectrum In Vivo Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
IVIS Spectrum In Vivo Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
1000x1000_Opera_Phenix

Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
FMT In Vivo Imaging Instrument

FMT 4000 In Vivo Imaging System

The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
FMT In Vivo Imaging Instrument

FMT 1000 In Vivo Imaging System

The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
1000x1000_Operetta

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
Receptor-expressing cell lines

ValiScreen Histamine H2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

IL-31 (Human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for IL-31 enables the quantitative determination of human IL-31 in serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows no cross-reactivity with mouse IL31. Cross-reactivity with other species has not been tested.
Price Range : 644.00 USD - 19300.00 USD
LANCE Detection Kit

CCL2/MCP-1α (mouse) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse CCL2/MCP-1α Detection Kit is designed for detection and quantitation of mouse Monocyte Chemoattractant Protein 1α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11000.00 USD

IL-33 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human IL-33 enables the quantitative determination of human interleukin-33 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 15000.00 USD

TNFα (mouse) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse TNFα Detection Kit is designed for detection and quantitation of mouse tumor necrosis factor α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11000.00 USD
Receptor-expressing cell lines

ValiScreen Chemokine CCR6 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
AlphaLisa Analyte 2

Heme oxygenase 2, liquid (AlphaLISA)

Human heme oxygenase 2 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human HO-2 Detection Kit, but can also be ordered separately.
List Price : 243.00 USD
LANCE Detection Kit

IL-17A (mouse/rat) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse/Rat IL-17A Detection Kit is designed for detection and quantitation of mouse or rat interleukin 17A in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11100.00 USD
PerkinElmer

TSA Cyanine 3 Reagent Pack

TSA® Cyanine 3 (Cy3) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra Cy3 in the localized area of the probe or antibody.
Price Range : 330.00 USD - 1547.00 USD
Receptor-expressing cell lines

Bradykinin rB1AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

Chemokine XCR1 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Anti-DNP HRP Conjugate

Anti-DNP antibody conjugated to horseradish peroxidase
List Price : 289.00 USD
Receptor-expressing cell lines

cAMPZen FroZen Cells, Histamine H2, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 636.00 USD
AlphaLISA immunoassay kits

IL-8 (human) AlphaLISA Biotin-Free Detection Kit

The AlphaLISA Human IL8 Biotin-Free Detection Kit is designed for the quantitative detection of human IL-8 in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).
Price Range : 724.00 USD - 10500.00 USD
AlphaLISA immunoassay kits

CXCL12/SDF-1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human CXCL12 (SDF-1) enables the quantitative determination of human CXCL12 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 451.00 USD - 9900.00 USD

CCL1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human CCL1 enables the quantitative determination of human chemokine (C-C motif) ligand 1 in serum and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 750.00 USD - 10600.00 USD
RediJect Inflammation Probe Standard Kit

XenoLight RediJect Chemiluminescent Inflammation Probe (Standard kit)

XenoLight RediJect Inflammation probe is a chemiluminescent in vivo reagent for monitoring Inflammation. This probe is offered in a ready-to-use format and can be conveniently applied to study myeloperoxidase (MPO) activity of activated phagocytes.
List Price : 300.00 USD
PerkinElmer

Membrane Target Systems: Chemokine XCR1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 982.00 USD

IL-8 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-8 Detection Kit is designed for detection and quantitation of human interleukin 8 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11000.00 USD
AlphaLISA immunoassay kits

TNFα (bovine) AlphaLISA Detection Kit

The AlphaLISA immunoassay kit for detection and quantitation of bovine TNFα in serum, plasma, cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Price Range : 672.00 USD - 10700.00 USD
AlphaLISA immunoassay kits

IL-6 (human) AlphaLISA Biotin-free Detection Kit

The AlphaLISA Human IL-6 Biotin-Free Detection Kit is designed for the quantitative detection of human IL-6 in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).
Price Range : 451.00 USD - 9900.00 USD
AlphaLisa Analyte 2

IL-5 (mouse), lyophilized (AlphaLISA)

Mouse IL-5 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA mouse IL-5 Detection Kit, but can also be ordered separately.
List Price : 308.00 USD
AlphaLISA immunoassay kits

IL-18BP (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human IL-18BP enables the quantitative determination of human interleukin 18-binding protein in serum and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 782.00 USD - 11600.00 USD
AlphaLISA immunoassay kits

TSLP (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human TSLP enables the quantitative determination of human TSLP in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 15000.00 USD
AlphaLisa Analyte 2

TSLP (human), lyophilized (AlphaLISA)

Human TSLP standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human TSLP Detection Kit, but can also be ordered separately.
List Price : 308.00 USD
Receptor-expressing cell lines

cAMPZen Frozen cells, Chemokine CCR7, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 636.00 USD
AlphaLISA immunoassay kits

CYR61 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human cysteine rich angiogenic inducer 61 (CYR61) enables the quantitative determination of human Cyr61 in serum and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD
alphaimmunoassay1

IL-17 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin-17 (IL-17, IL17A) Detection Kit is designed for detection and quantitation of human IL-17 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1585.00 USD - 10500.00 USD
AlphaLISA immunoassay kits

IL-10 (mouse) AlphaLISA Detection Kit

The AlphaLISA® Mouse Interleukin-10 (IL-10) Detection Kit is designed for detection and quantitation of mouse IL-10 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1585.00 USD - 10500.00 USD
PerkinElmer

CXCL9/MIG (human), lyophilized (LANCE)

Human CXCL9 standard, lyophilized, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra human CXCL9/MIG Detection Kit, but can be ordered separately.
List Price : 250.00 USD
In vivo Fluorescent Agents

MMPSense 645 FAST Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 731.00 USD
AlphaLISA immunoassay kits

IL-13 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin 13 Detection Kit is designed for detection and quantitation of human IL-13 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1585.00 USD - 10500.00 USD
Receptor-expressing cell lines

ValiScreen Chemokine CXCR2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
TSA -Plus Fluorescein System

TSA Plus Fluorescein

TSA® Plus fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 223.00 USD - 1779.00 USD
LANCE Detection Kit

IL-28B (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-28B Detection Kit is designed for detection and quantitation of human IL-28B in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 930.00 USD - 12400.00 USD
AlphaLISA immunoassay kits

IL-5 (mouse) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for mouse IL-5 enables the quantitative determination of mouse interleukin-5 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 15000.00 USD
AlphaLISA immunoassay kits

Fibrinogen (human) AlphaLISA Detection Kit

The AlphaLISA® Human Fibrinogen Detection Kit is designed for detection and quantitation of Human fibrinogen in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 465.00 USD - 10500.00 USD
AlphaLISA immunoassay kits

CXCL10/IP-10 (mouse) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for mouse Interferon Gamma Induced Protein 10 (mIP-10)/CXCL10 enables the quantitative determination of mouse IP-10 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 451.00 USD - 9900.00 USD
AlphaLisa Analyte 2

IL-6 (monkey), lyophilized (AlphaLISA)

Cynomolgus monkey IL-6 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA monkey IL-6 Detection Kit, but can also be ordered separately.
List Price : 308.00 USD

"Inflammation" 1-50 of 332 Products and Services

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