PerkinElmer

Inflammation Research

OF

Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

Products & Services (317)
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Product Type
  • Accessories (43)
  • Consumables (2)
  • Instruments (7)
  • Reagents (263)
  • Software and Informatics (2)
Assay Target
  • CCL1 (1)
  • CCL18 (1)
  • CCL2 (3)
  • CCL3 (3)
  • CCL4 (1)
  • CCL5 (3)
  • CCL8 (1)
  • CRP (1)
  • CXCL1 (2)
  • CXCL1/GROα (2)
  • CXCL10 (3)
  • CXCL13 (4)
  • CXCL4/PF4 (2)
  • CXCL9 (3)
  • Cyr61 (1)
  • ERK1/2 (1)
  • Fibrinogen (2)
  • G-CSF (1)
  • GM-CSF (1)
  • HO-1 (2)
  • HO-2 (2)
  • HVEM (2)
  • IFN-λ2 (4)
  • IFNα (2)
  • IFNγ (10)
  • IKKα (1)
  • IL-18 (1)
  • IL-1RA (4)
  • IL-23 (2)
  • IL-23A (2)
  • IL-3 (2)
  • IL-31 (2)
  • IL-6 (3)
  • IL-7A (2)
  • IL10 (2)
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  • IL12 (7)
  • IL12/p70 (1)
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  • IL15 (1)
  • IL17A (5)
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  • IL18BP (2)
  • IL1α (4)
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  • IL33 (4)
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  • IL8 (3)
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  • MCP2 (1)
  • MIP1α (2)
  • MLKL (6)
  • Osteoprotegerin (3)
  • PDGF (2)
  • Periostin (1)
  • PLC G2 (5)
  • Rb (1)
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  • SLP76 (2)
  • STAT1 (3)
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  • TNFα (12)
  • TNRFR1 (1)
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  • TREM2 (1)
  • TSLP (2)
Application
  • cAMP (10)
  • Drug Discovery & Development (12)
  • High biotin samples (6)
  • In vivo imaging (1)
  • Protein Analysis & Detection (164)
  • Protein Detection (26)
  • Protein-protein interactions (2)
  • Target Engagement (1)
Therapeutic Area
  • Angiogenesis (12)
  • Arthritis (6)
  • Atherosclerosis (4)
  • Autoimmunity (12)
  • Cardiovascular (11)
  • Central Nervous System (12)
  • Gastrointestinal (4)
  • Immuno-oncology (2)
  • Inflammation (231)
  • Metabolic (10)
  • Neuroinflammation (10)
  • Oncology (24)
  • Oncology/Cancer (7)
  • Pain (8)
  • Vascular disease (3)
Product Brand Name
  • AequoScreen (11)
  • AequoZen (8)
  • Alpha SureFire CETSA (1)
  • AlphaLISA (125)
  • AlphaLISA SureFire Ultra (26)
  • AlphaLISA SureFire Ultra Multiplex (8)
  • AlphaPlex (4)
  • cAMPZen (8)
  • IVIS (6)
  • IVISbrite (1)
  • IVISense (9)
  • LANCE Ultra (43)
  • Membrane Target Systems (8)
  • Operetta (28)
  • Operetta CLS (9)
  • Operetta CLS AND Opera Phenix (9)
  • ValiScreen (10)
Detection Method
  • Alpha (163)
  • Fluorescence (1)
  • Time-Resolved Fluorescence (TRF) (25)
  • TR-FRET (25)
  • Transmission (1)
Receptor Type
  • Anaphylatoxin (1)
  • Bradykinin (4)
  • Chemokine (28)
  • Histamine (10)
  • Prostanoid (2)
Assay Validated
  • Binding (23)
  • Calcium Fluorescence (7)
  • Calcium Luminescence (19)
  • cAMP (16)
  • Downstream Phosphorylation (7)
  • GTPγS (9)
  • Inositol Phosphate (2)
Fluorescent Agent Type
  • Activatable (4)
  • Targeted (1)
  • Vascular (3)
Assay Points (200-50,000)
  • 0 (1)
  • 100 (83)
  • 10000 (57)
  • 500 (146)
  • 5000 (88)
  • 50000 (30)
Assay Target Class
  • Cytokine (146)
  • GPCR (45)
  • Phosphoprotein (18)
  • Protein (41)
Automation Compatible
  • Yes (208)
Experimental Type
  • In vitro (160)
Format
  • Microplates (141)
Host Cell
  • CHO-K1 (43)
  • HEK293 (2)
Imaging Modality
  • Chemilumiluminescence (1)
  • Fluorescence (1)
  • High Content (1)
  • microCT Imaging (1)
  • Optical Imaging (6)
Length
  • 98.0 (1)
  • 98.0 cm (1)
Model Compatible With
  • Opera Phenix Plus (1)
  • Operetta (29)
  • Operetta CLS (8)
  • Operetta CLS AND Opera Phenix (10)
Type
  • Explorer Kit (1)
  • Standard Kit (1)

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1-25 of 317 Products & Services

  • Operetta CLS High-Content Analysis System

    Operetta CLS High-Content Analysis System

    Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
  • Spectrum-CU-Hero

    IVIS Spectrum In Vivo Imaging System

    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS In Vivo Imaging System

    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • IVIS-SpectrumCT-Hero

    IVIS® SpectrumCT In Vivo Imaging System

    The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina III In Vivo Imaging System

    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina LT In Vivo Imaging System

    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • SpectrumBL-CU-Hero

    IVIS® SpectrumBL High-Throughput In Vivo Optical Imaging System

    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • AlphaLISA SureFire Ultra total-protein

    Total STAT1 AlphaLISA SureFire Ultra Detection Kit

    The AlphaLISA® SureFire® Ultra™ total STAT1 assay is a sandwich immunoassay for quantitative detection of STAT1 (phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be a normalization phosphorylation studies.

    Price Range : 553.00 USD - 36700.00 USD
  • Receptor-expressing cell lines

    Chemokine CCR1, Human Recombinant, CHO-K1 cAMPZen Frozen cells

    Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
    List Price : 682.00 USD
  • Receptor-expressing cell lines

    Chemokine CCR1 ValiScreen Cell Line

    Stable, recombinant ValiScreen® cell line expressing the Chemokine receptor CCR1, human recombinant in CHO-K1 host cells.

  • Receptor-expressing cell lines

    Bradykinin B1 AequoScreen cell line

    Stable, recombinant AequoScreen® cell line expressing aequorin and the Bradykinin B1 receptor, human recombinant in CHO-K1 host cells.

  • IL-5 (mouse) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for mouse IL-5 enables the quantitative determination of mouse interleukin-5 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 752.00 USD - 18100.00 USD
  • LANCE Ultra Biomarker

    IFN-α (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human IFN-α Detection Kit is designed for detection and quantitation of human interferon α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 903.00 USD - 12000.00 USD
  • Receptor-expressing cell lines

    Chemokine CCR6 AequoScreen cell line

    Stable, recombinant AequoScreen® cell line expressing aequorin and the Chemokine receptor CCR6, human recombinant in CHO-K1 host cells.

  • LANCE standard

    IL-6 (human), lyophilized (LANCE), 0.1 µg

    Human Interleukin 6 (IL-6) standard, lyophilized, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra human IL-6 Detection Kit, but can be ordered separately.
    List Price : 273.00 USD
  • Total STAT4 AlphaLISA SureFire Ultra Detection Kit

    The AlphaLISA® SureFire® Ultra™ total STAT4 assay is a sandwich immunoassay for quantitative detection of STAT4 (phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be a normalization phosphorylation studies.

  • IFNβ (mouse) AlphaLISA Detection Kit

    The AlphaLISA® mouse Interferon β (IFNβ) Detection Kit is designed for detection and quantitation of mouse IFNβ in buffered solution, or cell culture in a homogeneous AlphaLISA assay (no wash steps).

    Price Range : 1589.00 USD - 12600.00 USD
  • AlphaLisa Analyte 2

    IL-5 (mouse), lyophilized (AlphaLISA)

    Mouse IL-5 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA mouse IL-5 Detection Kit, but can also be ordered separately.
    List Price : 370.00 USD
  • CXCL10/IP-10 (mouse) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for mouse Interferon Gamma Induced Protein 10 (mIP-10)/CXCL10 enables the quantitative determination of mouse IP-10 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 542.00 USD - 11900.00 USD
  • IL-17A (mouse/rat) AlphaLISA Biotin-free Detection Kit

    The AlphaLISA® Mouse/Rat IL-17A Biotin-Free Detection Kit is designed for the quantitative detection of mouse or rat IL-17 (IL-17A) in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).

    This is a replacement for AL544.

    Price Range : 576.00 USD - 12600.00 USD
  • LANCE Ultra Biomarker

    IL-6 (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra human IL-6 Detection Kit is designed for detection and quantitation of human interleukin-6 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 903.00 USD - 12000.00 USD
  • Receptor-expressing cell lines

    Chemokine CX3CR1 AequoScreen cell line

    Stable, recombinant AequoScreen® cell line expressing aequorin and the Chemokine receptor CX3CR1, human recombinant in CHO-K1 host cells.

  • LANCE Ultra Biomarker

    IL-12/p40 (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human IL-12/p40 Detection Kit is designed for detection and quantitation of human interleukin-12/p40 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 903.00 USD - 12000.00 USD
  • AlphaLISA Sandwich Anti-AnalyteConjugatedAcceptorBead

    IL-31 (Human) AlphaLISA Detection Kit

    The AlphaLISA® Human IL-31 Detection Kit is designed for detection and quantitation of human interleukin 31 in cell culture media using a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 775.00 USD - 23300.00 USD
  • IL-25 (mouse) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for mouse IL-25 enables the quantitative determination of mouse interleukin-25 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 752.00 USD - 18100.00 USD
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Resource Library (543)
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