PerkinElmer

Inflammation Research

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Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

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1-25 of 326 Products & Services

  • FMT In Vivo Imaging Instrument
    Quick View

    FMT 1000 In Vivo Imaging System

    FMT1000-750MSIM
    The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System
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    IVIS® Lumina III In Vivo Imaging System

    CLS136334
    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • IVIS-SpectrumCT-Hero
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    IVIS® SpectrumCT In Vivo Imaging System

    128201
    The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • Operetta CLS High-Content Analysis System
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    Operetta CLS High-Content Analysis System

    HH16000000
    Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS™ high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS™ lets you find even subtle phenotypic changes.
  • Spectrum-CU-Hero
    Quick View

    IVIS Spectrum In Vivo Imaging System

    124262
    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray
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    IVIS Lumina XRMS In Vivo Imaging System

    CLS136340
    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System
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    IVIS® Lumina LT In Vivo Imaging System

    CLS136331
    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • SpectrumBL-CU-Hero
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    IVIS® SpectrumBL High-Throughput In Vivo Optical Imaging System

    CLS137325
    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
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    CCL4/MIP-1ß (human) AlphaLISA Detection Kit

    AL258C , AL258F
    The AlphaLISA® Human C-C Motif Chemokine 4 / Macrophage Inflammatory Protein-1beta (CCL4 / MIP-1ß) Detection Kit is designed for detection and quantitation of human CCL4/MIP-1ß in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 2035.00 USD - 12600.00 USD
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    IL-8 (human) AlphaLISA Detection Kit

    AL224C , AL224F
    The AlphaLISA Human IL8 Detection Kit is designed for the quantitative determination of human IL-8 in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.
    Price Range : 1905.00 USD - 12600.00 USD
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    Phospho-TBK1 (Ser172) AlphaLISA SureFire Ultra Detection Kit

    ALSU-PTBK1-A500 , ALSU-PTBK1-A10K , ALSU-PTBK1-A50K , ALSU-PTBK1-A-HV

    The AlphaLISA® SureFire® Ultra™ p-TBK1 (Ser172) assay is a sandwich immunoassay for quantitative detection of phospho-TBK1 (phosphorylated on Ser172) in cellular lysates using Alpha Technology.

    Price Range : 553.00 USD - 36700.00 USD
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    IL-17F (human) AlphaLISA Detection Kit

    AL391HV , AL391C , AL391F
    The AlphaLISA® Human IL-17F Detection Kit is designed for detection and quantitation of human interleukin 17F in cell culture media or serum using a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 774.00 USD - 23300.00 USD
  • AlphaLISA Sandwich Anti-AnalyteConjugatedAcceptorBead
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    IL-6 (human) AlphaLISA Detection Kit

    AL223C , AL223F
    The AlphaLISA® Human Interleukin-6 (IL6) Detection Kit is designed for detection and quantitation of human IL-6 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1905.00 USD - 12600.00 USD
  • AlphaLisa Analyte 2
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    HVEM (human), lyophilized (AlphaLISA)

    AL3054S
    Human HVEM standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human HVEM Detection Kit, but can also be ordered separately.
    List Price : 506.00 USD
  • AlphaLISA Sandwich Anti-AnalyteConjugatedAcceptorBead
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    IL-10 (human) AlphaLISA Detection Kit

    AL218C , AL218F
    The AlphaLISA® Human Interleukin-10 (IL-10) Detection Kit is designed for detection and quantitation of human IL-10 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1905.00 USD - 12600.00 USD
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    IL-18BP (human) AlphaLISA Detection Kit

    AL3096HV , AL3096C , AL3096F
    The AlphaLISA® immunoassay kit for human IL-18BP enables the quantitative determination of human interleukin 18-binding protein in serum and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 939.00 USD - 14000.00 USD
  • Membrane Target Systems
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    Membrane Target Systems: Histamine H1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

    ES-390-M400UA
    Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
    List Price : 1044.00 USD
  • LANCE Ultra Biomarker
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    IL-12/p40 (human) LANCE Ultra TR-FRET Detection Kit

    TRF1382C , TRF1382M
    The LANCE® Ultra Human IL-12/p40 Detection Kit is designed for detection and quantitation of human interleukin-12/p40 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 903.00 USD - 12000.00 USD
  • In vivo Fluorescent Agents
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    ProSense Fluorescent Imaging Agent

    NEV10003 , NEV10001EX , NEV11171
    Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time. PerkinElmer’s ProSense® imaging agents are protease activatable NIR fluorescent probes that are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation. ProSense is available in 3 formats; 680, 750 EX, and 750 FAST.
    Price Range : 640.00 USD - 756.00 USD
  • AlphaLISA SureFire Ultra Phospho-protein
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    Phospho-PLC G2 (Tyr1197) AlphaLISA SureFire Ultra Detection Kit

    ALSU-PPLCG2-C500 , ALSU-PPLCG2-C10K , ALSU-PPLCG2-C50K , ALSU-PPLCG2-C-HV

    The AlphaLISA® SureFire® Ultra™ p-PLC G2 (Tyr1197) assay is a sandwich immunoassay for quantitative detection of phospho-PLC G2 (phosphorylated on Tyr1197) in cellular lysates using Alpha Technology.

    Price Range : 526.00 USD - 34900.00 USD
  • Quick View

    Alpha SureFire Ultra Multiplex Phospho/Total ERK1/2 Assay Kit

    MPSU-PTERK-M500 , MPSU-PTERK-M10K , MPSU-PTERK-M50K , MPSU-PTERK-M-HV
    The AlphaLISA® SureFire® Ultra™ Multiplex phospho-ERK1/2 (Thr202/Tyr204) + Total ERK assay kit is used to measure both the phosphorylation of ERK1/2 and total levels of endogenous ERK1/2 in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure ERK1/2phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
    Price Range : 995.00 USD - 63800.00 USD
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    TNFα (porcine) AlphaLISA Detection Kit

    AL548HV , AL548C , AL548F
    The AlphaLISA® immunoassay kit for porcine TNFα enables the detection and quantitation of porcine TNFα in porcine serum, plasma, and, cell lysyate, cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows minimal cross-reactivity with human and bovine TNFα and no cross reactivity towards porcine IFNγ.
    Price Range : 780.00 USD - 25400.00 USD
  • LANCE Ultra Biomarker
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    IFN-λ2 (human) LANCE TR-FRET Detection Kit

    TRF3039C , TRF3039M
    The LANCE® Ultra Human IFN-λ2 Detection Kit is designed for detection and quantitation of human interferon λ2 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 1768.00 USD - 12000.00 USD
  • Quick View

    IL-4 (human) AlphaLISA Detection Kit

    AL266C , AL266F
    The AlphaLISA® Human Interleukin 4 (IL4) Detection Kit is designed for detection and quantitation of human IL4 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1905.00 USD - 13300.00 USD
  • Receptor-expressing cell lines
    Quick View

    ValiScreen Histamine H1 (human) cell line

    ES-390-C

    Stable, recombinant ValiScreen® cell line expressing the Histamine H1 receptor, human recombinant in CHO-K1 host cells.

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