PerkinElmer

In Vivo Research

OF

Streamline preclinical validation of therapeutics and diagnostics in development to potential clinical translation with our high performance translational in vivo research tools.

  • Preclinical screening of target compounds: Optical imaging platforms as high-throughput screening tools to evaluate efficacy of your therapeutic compounds or specificity of diagnostic molecules in development.
  • Multimodality for greater insight: evaluate the underlying morphological effects of your treatment regimen with the combined power of functional and anatomical imaging using our integrated platform or by co-registering with our standalone microCT imaging system.
  • Clinical modalities in preclinical evaluation: Expedite evaluation of your contrast agents using our microCT imaging systems.

For research use only. Not for use in diagnostic procedures.

Products & Services (78)
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1-25 of 78 Products & Services

  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina III In Vivo Imaging System

    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS In Vivo Imaging System

    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina LT In Vivo Imaging System

    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • IVIS-SpectrumCT-Hero

    IVIS® SpectrumCT In Vivo Imaging System

    The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • FMT In Vivo Imaging Instrument

    FMT 1000 In Vivo Imaging System

    The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
  • Spectrum-CU-Hero

    IVIS Spectrum In Vivo Imaging System

    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • SpectrumBL-CU-Hero

    IVIS® SpectrumBL High-Throughput In Vivo Optical Imaging System

    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • Quantum GX2 microCT imaging system

    Quantum GX2 microCT Imaging System

    Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
  • Bioware Bioluminescent Oncology Cell LInes

    Bioware® Brite Cell Line 4T1-Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • Bioluminescent Oncology Cell Lines - Bioware

    Bioware® Brite Cell Line K562 Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • Bioluminescent Oncology Cell Lines - Bioware

    Bioware® Brite Cell Line HT29 Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • Bioware Bioluminescent Oncology Cell LInes

    Bioware® Brite Cell Line 4T1-Red-FLuc-GFP

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • RediFect™ Lentiviral Particles

    RediFect Lentiviral Particles

    Create the bioluminescent cell line you need.

    Stably-transfect cells with prepackaged lentivirus particles expressing a combination of novel luciferases and a fluorescent protein for monitoring tumor growth, tracking primary or stem cells in vivo, and other applications.  

    PerkinElmer’s RediFect lentiviral particles contain Red-Fluc, the same red-shifted firefly luciferase (Luciola italica) as our Bioware® Brite cell lines, for a stable bioluminescent signal excellent for deep tissue imaging; or use our green-shifted Renilla luciferase (Renilla reniformis) transgene. Both offer efficient transduction of a wide variety of mammalian cell lines including most cancer cell lines, primary, stem and non-dividing cells. Bioluminescent cells can be imaged using our luciferin or coelenterazine substrates.

    Price Range : 1710.00 USD - 1714.00 USD
  • In vivo Fluorescent Agents

    ProSense Fluorescent Imaging Agent

    Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time. PerkinElmer’s ProSense® imaging agents are protease activatable NIR fluorescent probes that are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation. ProSense is available in 3 formats; 680, 750 EX, and 750 FAST.
    Price Range : 640.00 USD - 756.00 USD
  • Bioware U87 Glioblastoma Bioluminescent Oncology Cell Line

    Bioware® Brite Cell Line U87 MG-Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • Bioluminescent Oncology Cell Lines - Bioware

    Bioware® Brite Cell Line HepG2-Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • In vivo Fluorescent Agents

    Cat B 680 FAST Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.  
    List Price : 817.00 USD
  • In vivo Fluorescent Agents

    IntegriSense Fluorescent Imaging Agent

    Integrins are a superfamily of transmembrane cell surface receptors that mediate signal transduction, cell-to-cell interaction, and cell-to-extracellular matrix adhesion - key processes for healthy cells as well as progression of disease states such as atherosclerosis and cancer, where integrins contribute to angiogenesis, tumorigenesis, and metastasis.

    Among this superfamily, αvβ3 integrin holds promise as a therapeutic target in areas such as immuno-oncology, where αvβ3 integrin may prevent tumors from evading the immune system. PerkinElmer's IntegriSense fluorescence probes are designed to target αvβ3 integrin for monitoring tumor growth, angiogenesis and assessing treatment efficacy.

    Price Range : 764.00 USD - 778.00 USD
  • Bioluminescent Oncology Cell Lines - Bioware

    Bioware® Brite Cell Line BxPC3-Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • Bioluminescent Oncology Cell Lines - Bioware

    Bioware® Brite Cell Line PC3 Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • XenoLight DiR Fluorescent Dye

    XenoLight DiR Fluorescent Dye

    XenoLight DiR NIR Fluorescent Dye can be used for non-invasive imaging of T-cell or stem cell homing in vivo
    List Price : 196.00 USD
  • RediJect 2-DG Fluorescent Imaging Probe (Standard kit)

    XenoLight RediJect 2-DeoxyGlucosone (DG) 750 is a fluorescent imaging probe for in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, the probe has been designed to contain four 2-DG molecules per dye molecule.  
    List Price : 555.00 USD
  • In vivo Fluorescent Agents

    HypoxiSense 680 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 659.00 USD
  • In vivo Fluorescent Agents

    Cat B 750 FAST Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.  
    List Price : 793.00 USD
  • Bioluminescent Oncology Cell Lines - Bioware

    Bioware® Brite Cell Line SKOV3 Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
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