PerkinElmer

In Vivo Research

OF

Streamline preclinical validation of therapeutics and diagnostics in development to potential clinical translation with our high performance translational in vivo research tools.

  • Preclinical screening of target compounds: Optical imaging platforms as high-throughput screening tools to evaluate efficacy of your therapeutic compounds or specificity of diagnostic molecules in development.
  • Multimodality for greater insight: evaluate the underlying morphological effects of your treatment regimen with the combined power of functional and anatomical imaging using our integrated platform or by co-registering with our standalone microCT imaging system.
  • Clinical modalities in preclinical evaluation: Expedite evaluation of your contrast agents using our microCT imaging systems.

For research use only. Not for use in diagnostic procedures.

Products & Services (79)
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  • Instruments (8)
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1-25 of 79 Products & Services

  • Quantum GX2 microCT imaging system

    Quantum GX2 microCT Imaging System

    Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
  • Spectrum-CU-Hero

    IVIS Spectrum In Vivo Imaging System

    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina III In Vivo Imaging System

    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • FMT In Vivo Imaging Instrument

    FMT 1000 In Vivo Imaging System

    The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
  • IVIS-SpectrumCT-Hero

    IVIS® SpectrumCT In Vivo Imaging System

    The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS In Vivo Imaging System

    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • SpectrumBL-CU-Hero

    IVIS® SpectrumBL High-Throughput In Vivo Optical Imaging System

    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina LT In Vivo Imaging System

    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • In vivo Fluorescent Agents

    TLectinSense 680 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 672.00 USD
  • In vivo Fluorescent Agents

    MMPSense Fluorescent Imaging Agent

    Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

    PerkinElmer’s MMPSense NIR activatable fluorescence agents are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

    Price Range : 778.00 USD - 779.00 USD
  • In vivo Fluorescent Agents

    AngioSPARK 680 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
    List Price : 890.00 USD
  • VivoTag Fluorochrome - 1 mg quantity

    VivoTag Fluorescent Dyes

    Label antibodies, small molecules, proteins, or peptides with VivoTag® NIR fluorescent dyes.

    Available as either NHS esters or maleimide reactive dyes, making conjugation to either free amine (-NH3) or free thiol (-SH) containing molecules possible, our VivoTag fluorescent dyes have been validated for in vivo and in vitro applications. Please refer to the configuration table below to see which VivoTag fluorescent agent is best for your research studies.

    VivoTag is available in multiple sizes and wavelengths to fit your imaging needs.

    Price Range : 189.00 USD - 741.00 USD
  • In vivo Fluorescent Agents

    AngioSense Fluorescent Imaging Agent

    In vivo optical imaging of vascular changes and vascular leak is an emerging modality for studying altered physiology in a variety of different cancers and inflammatory states. In oncology, increases in tumor vascular permeability can be an early indicator of tumor angiogenesis. In inflammatory disease increased vascular permeability can indicate alterations in fluid homeostasis in an acute edema response or in chronic organ conditions.

    PerkinElmer’s AngioSense® NIR fluorescent probes are designed to evaluate vascular changes to better understand various disease states or provide valuable information on effects of drug candidates earlier in the development process.

    List Price : 640.00 USD
  • In vivo Fluorescent Agents

    ProSense Fluorescent Imaging Agent

    Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time. PerkinElmer’s ProSense® imaging agents are protease activatable NIR fluorescent probes that are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation. ProSense is available in 3 formats; 680, 750 EX, and 750 FAST.
    Price Range : 640.00 USD - 756.00 USD
  • Bioware U87 Glioblastoma Bioluminescent Oncology Cell Line

    Bioware® Brite Cell Line U87 MG-Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • RediJect Control Kit

    RediJect Bacterial Detection Fluorescent Imaging Probe (Control Dye)

    XenoLight RediJect Bacterial Detection control dye is a non-reactive dye that can be used as a negative control when using the RediJect Bacterial Detection 750 fluorescent imaging probe. 
    List Price : 166.00 USD
  • Bioware Bioluminescent Oncology Cell LInes

    Bioware® Brite Cell Line GL261 Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • Bioluminescent Oncology Cell Lines - Bioware

    Bioware® Brite Cell Line HT29 Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • RediJect Bioluminescent Substrates

    RediJect Coelenterazine h Bioluminescent Substrate

    RediJect Coelenterazine H is a bioluminescent substrate in a ready-to-use injectable format developed by the in vivo imaging leaders to fit your laboratory workflow.
    List Price : 386.00 USD
  • In vivo Fluorescent Agents

    OsteoSense Fluorescent Imaging Agents

    Image and quantify osteoporosis, arthritis, cancer metastases, and other bone diseases, as well as normal bone growth and resorption, in vivo with OsteoSense® Fluorescent Imaging probes. As opposed to other imaging modalities such as CT or x-ray which raise the risk of harmful irradiation to the subject, in vivo fluorescence imaging offers no radiation exposure concerns, and when performed with optimized hydroxyapatite-targeted probes such as OsteoSense, can image and quantify bone growth and elucidate the biology of bone remodeling.

    OsteoSense is available in 3 wavelengths: 680, 750, and 800.

    Price Range : 646.00 USD - 647.00 USD
  • In vivo Fluorescent Agents

    Genhance 680 Fluorescent Imaging Agent (5mg)

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 728.00 USD
  • Bioluminescent Oncology Cell Lines - Bioware

    Bioware® Brite Cell Line HCT116 Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • In vivo Fluorescent Agents

    IntegriSense Fluorescent Imaging Agent

    Integrins are a superfamily of transmembrane cell surface receptors that mediate signal transduction, cell-to-cell interaction, and cell-to-extracellular matrix adhesion - key processes for healthy cells as well as progression of disease states such as atherosclerosis and cancer, where integrins contribute to angiogenesis, tumorigenesis, and metastasis.

    Among this superfamily, αvβ3 integrin holds promise as a therapeutic target in areas such as immuno-oncology, where αvβ3 integrin may prevent tumors from evading the immune system. PerkinElmer's IntegriSense fluorescence probes are designed to target αvβ3 integrin for monitoring tumor growth, angiogenesis and assessing treatment efficacy.

    Price Range : 764.00 USD - 778.00 USD
  • In vivo Fluorescent Agents

    Cat B 680 FAST Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.  
    List Price : 817.00 USD
  • In vivo Fluorescent Agents

    GFR-Vivo 680 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 484.00 USD
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