PerkinElmer

In Vivo Research

OF

Streamline preclinical validation of therapeutics and diagnostics in development to potential clinical translation with our high performance translational in vivo research tools.

  • Preclinical screening of target compounds: Optical imaging platforms as high-throughput screening tools to evaluate efficacy of your therapeutic compounds or specificity of diagnostic molecules in development.
  • Multimodality for greater insight: evaluate the underlying morphological effects of your treatment regimen with the combined power of functional and anatomical imaging using our integrated platform or by co-registering with our standalone microCT imaging system.
  • Clinical modalities in preclinical evaluation: Expedite evaluation of your contrast agents using our microCT imaging systems.

For research use only. Not for use in diagnostic procedures.

Products & Services (70)
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1-25 of 70 Products & Services

  • Quantum GX2 microCT imaging system

    Quantum GX2 microCT Imaging System

    Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
  • Spectrum-CU-Hero

    IVIS Spectrum In Vivo Imaging System

    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS In Vivo Imaging System

    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • IVIS-SpectrumCT-Hero

    IVIS® SpectrumCT In Vivo Imaging System

    The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina III In Vivo Imaging System

    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina LT In Vivo Imaging System

    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • SpectrumBL-CU-Hero

    IVIS® SpectrumBL High-Throughput In Vivo Optical Imaging System

    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • Bioware Bioluminescent Bacteria

    IVISbrite Proteus mirabilisXen44 Bioluminescent Bacterial Strain

    IVISbrite Proteus mirabilis Xen44 bioluminescent bacteria is derived from a parental strain from the American Type Culture Collection (ATCC), used under license. For in vitro or in vivo imaging applications, IVISbrite P. mirabilis-Xen44 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

    For research use only. Not for use in diagnostic procedures.

  • Bioware Bioluminescent Bacteria

    IVISbrite Salmonella typhimurium Xen33 Bioluminescent Bacterial Strain

    IVISbrite Salmonella typhimurium Xen33 bioluminescent bacteria was derived from the parental strain FDA 1189. For in vitro or in vivo imaging applications, IVISbrite S. typhimurium-Xen33 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

    For research use only. Not for use in diagnostic procedures.

  • Bioware Bioluminescent Bacteria

    IVISbrite Yersinia enterocolitic Xen25 Bioluminescent Bacterial Strain

    IVISbrite Yersinia enterocolitica Xen25 bioluminescent bacteria is derived from the parental strain WS2589. For in vitro or in vivo imaging applications, IVISbrite Y. enterocolitica-Xen25 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

    For research use only. Not for use in diagnostic procedures.

  • Bioware Bioluminescent Oncology Cell LInes

    IVISbrite 4T1 Red F-luc Bioluminescent Tumor Cell line (Bioware Brite)

    The IVISbrite 4T1 Red F-luc tumor cell line (Bioware® Brite 4T1-Red-FLuc) is a light-producing cell line derived from 4T1 mouse mammary gland adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

    For research use only. Not for use in diagnostic procedures.

  • Bioware Bioluminescent Bacteria

    IVISbrite Yersinia enterocolitic Xen24 Bioluminescent Bacterial Strain

    IVISbrite Yersinia enterocolitica Xen24 bioluminescent bacteria was derived from the 91A1854 clinical isolate. For in vitro or in vivo imaging applications, IVISbrite Y. enterocolitica-Xen24 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

    For research use only. Not for use in diagnostic procedures.

  • Bioware Bioluminescent Oncology Cell LInes

    IVISbrite NCI-H460 Red F-luc Bioluminescent Tumor Cell line (Bioware Brite)

    The IVISbrite NCI-H460 Red F-luc tumor cell line (Bioware® Brite NCI-H460-Red-FLuc) is a light-producing cell line derived from NCI-H460 human lung adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

    For research use only. Not for use in diagnostic procedures.

  • Bioware Bioluminescent Bacteria

    IVISbrite Shigella dysenteriae Xen27 Bioluminescent Bacterial Strain

    IVISbrite Shigella dysenteriae Xen27 bioluminescent bacteria is derived from the 88A6205 clinical isolate. For in vitro or in vivo imaging applications, IVISbrite S. dysenteriae-Xen27 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

    For research use only. Not for use in diagnostic procedures.

  • In vivo Fluorescent Agents

    IVISense Annexin-V 750 Fluorescent Probe (Annexin-Vivo)

    IVISense Annexin-V 750 fluorescent imaging probe (Annexin-Vivo) is designed to enable in vivo visualization and quantification of membrane-bound phosphatidylserine (PS) during the early stages of apoptosis.

    For research use only. Not for use in diagnostic procedures.

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    List Price : 849.00 USD
  • Bioluminescent Oncology Cell Lines - Bioware

    IVISbrite Colo205 Red F-luc Bioluminescent Tumor Cell line (Bioware Brite)

    The IVISbrite Colo205 Red F-luc tumor cell line (Bioware® Brite Colo205-Red-FLuc) is a light-producing cell line derived from Colo205-human colorectal adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

    For research use only. Not for use in diagnostic procedures.

  • P. aeruginosa bioluminescent bacteria

    IVISbrite Pseudomonas aeruginosa Xen41 Bioluminescent Bacterial Strain

    IVISbrite Pseudomonas aeruginosa Xen41 bioluminescent bacteria is derived from parental strain PAO1. For in vitro or in vivo imaging applications, IVISbrite P. aeruginosa-Xen41 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

    For research use only. Not for use in diagnostic procedures.

  • In vivo Fluorescent Agents

    IVISense Hypoxia CA IX 680 Fluorescent Probe (HypoxySense)

    IVISense Hypoxia CA IX 680 (HypoxiSense 680) is a carbonic anhydrase IX (CA IX) targeted fluorescent in vivo imaging probe that can be used to image CA IX overexpression in response to hypoxia. Oxygen deprivation is associated with several disease states including angiogenisis, pulmonary disease, inflammation, and cancer.

    For research use only. Not for use in diagnostic procedures.

    List Price : 659.00 USD
  • In vivo Fluorescent Agents

    IVISense Pan Cathepsin Fluorescent Probes (ProSense)

    Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time.

    PerkinElmer’s IVISense Pan Cathepsin fluorescent probes (ProSense®) are versatile pan-cathepsin-activatable NIR agents for imaging various disease-related events. These activatable probes are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation.

    For research use only. Not for use in diagnostic procedures.

    Price Range : 640.00 USD - 756.00 USD
  • In vivo Fluorescent Agents

    IVISense Vascular NP Fluorescent Nanoparticles (AngioSPARK)

    IVISense Vascular NP (AngioSPARK®) is a fluorescent nanoparticle probe with a long pharmacokinetic profile for imaging vascularity, vascular leak, blood-brain-barrier compromise, and vascular cell fluid-phase pinocytosis.

    PerkinElmer's IVISense Vascular NP fluorescent nanoparticle probes are available in 680 and 750 nm wavelengths ideal for multiplexing with other probes.

    For research use only. Not for use in diagnostic procedures.

    List Price : 890.00 USD
  • IVISense 2-DG 750 Fluorescent Probes - RediJect Solution (XenoLight)

    IVISense 2-DeoxyGlucosone (DG) (XenoLight 2-DG) fluorescent imaging probes in RediJect Solution enable in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, these probes have been designed to contain four 2-DG molecules per dye molecule.

    IVISense 2-DG probes are available in either 1 or 4 vial quantities and come in a convenient, ready-to-use injectable format.

    For research use only. Not for use in diagnostic procedures.

    List Price : 555.00 USD
  • Bioluminescent Oncology Cell Lines - Bioware

    IVISbrite HCT-116 Red F-luc Bioluminescent Tumor Cell line (Bioware Brite)

    The IVISbrite HCT116 Red F-luc tumor cell line (Bioware® Brite HCT-116-Red-FLuc) is a light-producing cell line derived from HCT116 human colorectal carcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

    For research use only. Not for use in diagnostic procedures..

  • VivoTrack-680 Fluorescent Labeling Kit - Standard Kit NEV12000

    IVISense 680 Fluorescent Cell Labeling Dyes (VivoTrack)

    Label and track mammalian cells including stem cells, T-cells, macrophages and more with IVISense 680 fluorescent cell labeling dye (VivoTrack).

    IVISense 680 is an NIR fluorescent lipophilic labeling dye that intercalates in the cell membrane. With high solubility and excellent stability, PerkinElmer's IVISense 680 fluorescent cell dye offers superior brightness and uniform labeling, ideal for cell detection in vitro and longitudinal cell tracking in vivo across many applications including inflammation, immunology, and stem cell research.

    For research use only. Not for use in diagnostic procedures.

    Price Range : 123.00 USD - 310.00 USD
  • P. aeruginosa bioluminescent bacteria

    IVISbrite Pseudomonas aeruginosa Xen05 Bioluminescent Bacterial Strain

    IVISbrite Pseudomonas aeruginosa Xen05 bioluminescent bacteria was derived from a human septicemia isolate from the American Type Culture Collection (ATCC), used under license. For in vitro or in vivo imaging applications, IVISbrite P. aeruginosa-Xen05 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

    For research use only. Not for use in diagnostic procedures.

  • In vivo Fluorescent Agents

    IVISense Renin 680 FAST Fluorscent Probe (ReninSense)

    IVISense Renin 680 FAST (ReninSense) is recognized and activated by rodent forms of renin in preclinical in vivo imaging models. IVISense Renin 680 FAST may be used to monitor abnormal Renin-Angiotensin System (RAS) function, progression of disease, and the efficacy of therapeutic treatment in disorders such as hypertension, cardiovascular disease, as well as some neurological diseases.

    For research use only. Not for use in diagnostic procedures.

    List Price : 793.00 USD
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