PerkinElmer

In Vivo Research

OF

Streamline preclinical validation of therapeutics and diagnostics in development to potential clinical translation with our high performance translational in vivo research tools.

  • Preclinical screening of target compounds: Optical imaging platforms as high-throughput screening tools to evaluate efficacy of your therapeutic compounds or specificity of diagnostic molecules in development.
  • Multimodality for greater insight: evaluate the underlying morphological effects of your treatment regimen with the combined power of functional and anatomical imaging using our integrated platform or by co-registering with our standalone microCT imaging system.
  • Clinical modalities in preclinical evaluation: Expedite evaluation of your contrast agents using our microCT imaging systems.

For research use only. Not for use in diagnostic procedures.

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1-25 of 71 Products & Services

  • IVIS-SpectrumCT-Hero

    IVIS® SpectrumCT In Vivo Imaging System

    The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina LT In Vivo Imaging System

    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • Quantum GX2 microCT imaging system

    Quantum GX2 microCT Imaging System

    Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
  • SpectrumBL-CU-Hero

    IVIS® SpectrumBL High-Throughput In Vivo Optical Imaging System

    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina III In Vivo Imaging System

    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS In Vivo Imaging System

    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • Spectrum-CU-Hero

    IVIS Spectrum In Vivo Imaging System

    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • RediJect Bioluminescent Substrates

    IVISbrite Coelenterazine h Bioluminescent Substrate - RediJect Solution (XenoLIght)

    IVISbrite Coelenterazine H in RediJect™ solution is a bioluminescent substrate in a ready-to-use injectable format developed by the in vivo imaging leaders to fit your laboratory workflow.

    For research use only. Not for use in diagnostic procedures.

    List Price : 386.00 USD
  • S. aureus Bioluminescent Bacteria

    IVISbrite Staphylococcus aureus Xen8.1 Bioluminescent Bacterial Strain

    IVISbrite Staphylococcus aureus Xen8.1 bioluminescent bacteria is derived from the parental strain 8325-4. For in vitro or in vivo imaging applications, IVISbrite S. aureus-Xen8.1 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

    For research use only. Not for use in diagnostic procedures.

  • IVISense Fluorescent Dyes (VivoTag)

    Label antibodies, small molecules, proteins, or peptides with IVISense NIR fluorescent dyes.

     

    PerkinElmer’s IVISense fluorescent dyes (VivoTag®) for labeling antibodies, small molecules, proteins, or peptides are designed specifically to enable customized development of novel superbright fluorescent imaging agents. Dye properties, such as excellent brightness, hydrolytic stability, and photostability, as well as selection for minimal interaction with biological tissue for no potential loss of specificity, have been optimized and validated for use in in vivo or in vitro imaging.

    Available as NHS esters or maleimide reactive dyes for conjugation to either free amine (-NH3) or free thiol (-SH) containing molecules. Conjugate an optimal 1-3 dyes onto your protein or choose self-quenching dyes to make your own custom fluorogenic probes.

    For research use only. Not for use in diagnostic procedures.

    Price Range : 189.00 USD - 741.00 USD
  • RediJect Inflammation Probe Explorer Kit

    IVISbrite MPO 425 Chemiluminescent Probes - RediJect Solution (XenoLight)

    IVISbrite MPO 425 Chemiluminescent Probe in RediJect Solution ((XenoLight RediJect Inlammation Probe) is an in vivo imaging reagent for monitoring Inflammation. This probe is available in a ready-to-use format and can be conveniently applied to study myeloperoxidase (MPO) activity of activated phagocytes.

    For research use only. Not for use in diagnostic procedures.

    Price Range : 130.00 USD - 326.00 USD
  • S. aureus Bioluminescent Bacteria

    IVISbrite Staphylococcus aureus Xen29 Bioluminescent Bacterial Strain

    IVISbrite Staphylococcus aureus Xen29 bioluminescent bacteria was derived from a parental strain from the American Type Culture Collection (ATCC), used under license. For in vitro or in vivo imaging applications, IVISbrite S. aureus-Xen29 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

    For research use only. Not for use in diagnostic procedures.

  • In vivo Fluorescent Agents

    IVISense Bombesin Receptor 680 Fluorescent Probe (BombesinRSense)

    IVISense Bombesin Receptor 680 (BombesinRSense 680) is a targeted NIR fluorescent probe for in vivo imaging applications that targets bombesin receptors expressed in many types of cancers.

    For research use only. Not for use in diagnostic procedures.

    List Price : 672.00 USD
  • Bioluminescent Oncology Cell Lines - Bioware

    IVISbrite PC3 Red F-luc-GFP Bioluminescent Tumor Cell line (Bioware Brite)

    The IVISbrite PC3 Red-F-luc-GFP tumor cell line (Bioware® Brite PC3-Red-FLuc-GFP) is a light-producing and fluorescent cell line derived from PC3 human prostate adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc) fused to GFP (Green Fluorescent Protein), for a brighter, red-shifted bioluminescent or green fluorescent signal.

    For research use only. Not for use in diagnostic procedures.

  • In vivo Fluorescent Agents

    IVISense Cat K 680 FAST Fluorescent Probe

    IVISense Cat K 680 FAST NIR fluorescent probe enables monitoring and quantifying cathepsin K (Cat K) activity.

    Cat K is a lysosomal cysteine protease expressed in osteoclasts, chondrocytes, and synovial fibroblasts and is involved in bone resorption and collagen degradation. Women with osteoporosis, breast cancer and bone metastases are reported to have high levels of Cat K. The high expression levels of Cat K is a good marker for not only better understanding bone modeling and remodeling, but evaluating inhibitors of Cat K for potential therapeutics.

    For research use only. Not for use in diagnostic procedures.

    List Price : 778.00 USD
  • In vivo Fluorescent Agents

    IVISense Transferrin Receptor 750 Fluorescent Probe (Transferrin-Vivo)

    Transferrin is an important serum protein that mediates iron transport into cells via the transferrin receptor, a function that is essential for cell growth and metabolism.

    PerkinElmer’s IVISense Transferrin Receptor 750 fluorescent probe (Transferrin-Vivo) is a NIR-labeled in vivo imaging probe that detects transferrin receptor levels associated with an altered metabolic need for iron in cancer and inflammatory cells. IVISense Transferrin Receptor 750 fluorescent agent also detects normal transferrin receptor levels in the liver as well as decreased expression due to altered iron metabolism associated with drug-induced liver injury.

    For research use only. Not for use in diagnostic procedures.

    List Price : 672.00 USD
  • Bioware Bioluminescent Oncology Cell LInes

    IVISbrite GL261 Red F-luc Bioluminescent Tumor Cell line (Bioware Brite)

    The IVISbrite GL261 Red F-luc tumor cell line (Bioware® Brite GL261-Red-FLuc) is a light-producing cell line derived from GL261 mouse glioma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

    For research use only. Not for use in diagnostic procedures.

  • In vivo Fluorescent Agents

    IVISense Acute Vascular Fluorescent Probes (Genhance)

    IVISense Acute Vascular (Genhance) fluorescent probes enable imaging and quantitation of acute vascular permeability increase, bladder clearance via intravital ureter imaging, or incorporation into liposomes for drug delivery monitoring.

    For research use only. Not for use in diagnostic procedures.

    Price Range : 191.00 USD - 728.00 USD
  • Bioware Bioluminescent Oncology Cell LInes

    IVISbrite LL/2 Red F-luc Bioluminescent Tumor Cell line (Bioware Brite)

    The IVISbrite LL/2 Red F-luc tumor cell line (Bioware® Brite LL/2-Red-FLuc) is a light-producing cell line derived from a mouse lung carcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

    For research use only. Not for use in diagnostic procedures.

  • Bioware Bioluminescent Bacteria

    IVISbrite Escherichia coli Xen14 Bioluminescent Bacterial Strain

    IVISbrite Escherichia coli Xen14 bioluminescent bacteria is derived from the parental strain E. coli WS2572, a clinical isolate from Weihenstephan Culture Collection. For in vitro or in vivo imaging applications, IVISbrite E. coli-Xen14 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.

    For research use only. Not for use in diagnostic procedures.

  • Bioluminescent Oncology Cell Lines - Bioware

    IVISbrite K562 Red F-luc Bioluminescent Tumor Cell line (Bioware Brite)

    The IVISbrite K562 Red F-luc tumor cell line ( Bioware® Brite K562-Red-FLuc) is a light-producing cell line derived from K562-human chronic myelogenous leukemia (CML). The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

    For research use only. Not for use in diagnostic procedures.

  • RediJect Probe Explorer Kit

    IVISense Bacterial 750 Fluorescent Probe - RediJect Soltuion

    IVISense Bacterial 750 (XenoLight Rediject Bacterial Detection) fluorescent probe is a near-infrared (NIR) fluorescent probe for in vivo targeting of both gram positive and gram negative bacterial infections.

    IVISense Bacterial 750 probes are available in either 1 or 4 vial quantities in a convenient, ready-to-use injectable format.

    For research use only. Not for use in diagnostic procedures.

    Price Range : 166.00 USD - 532.00 USD
  • Bioware U87 Glioblastoma Bioluminescent Oncology Cell Line

    IVISbrite U87MG Red F-luc Bioluminescent Tumor Cell line (Bioware Brite)

    The IVISbrite U87 MG Red F-luc tumor cell line (Bioware® Brite U87MG-Red-FLuc) is a light-producing cell line derived from U87 MG-human brain glioblastoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

    For research use only. Not for use in diagnostic procedures.

  • S. aureus Bioluminescent Bacteria

    IVISbrite Staphylococcus aureus Xen36 Bioluminescent Bacterial Strain

    IVISbrite Staphylococcus aureus Xen36 bioluminescent bacteria was derived from a parental strain from the American Type Culture Collection (ATCC), used under license. For in vitro or in vivo imaging applications, IVISbrite S. aureus-Xen36 possesses a stable copy of the Photorhabdus luminescens lux operon on the native plasmid.

    For research use only. Not for use in diagnostic procedures.

  • Bioluminescent Oncology Cell Lines - Bioware

    IVISbrite HCT-116 Red F-luc Bioluminescent Tumor Cell line (Bioware Brite)

    The IVISbrite HCT116 Red F-luc tumor cell line (Bioware® Brite HCT-116-Red-FLuc) is a light-producing cell line derived from HCT116 human colorectal carcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

    For research use only. Not for use in diagnostic procedures..

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