GPCR Research

G-protein coupled receptors (GPCR) are prominent targets in drug discovery. GPCRs are involved in most cellular responses to hormones and neurotransmitters and are essential for intracellular communication. Today, GPCR targeted drugs make up over a third of all approved drugs.

While GPCRs have been studied for decades, the complexities of these receptors in signaling are still being elucidated. As we better understand the role of GPCRs in different signaling pathways, such pathways are increasingly exploited for more targeted therapies, with fewer unwanted side effects.

PerkinElmer offers a variety of products to support GPCR research – for both functional and binding assays. 

  • Scalable GPCR cellular imaging, detection instrumentation and liquid handling systems for radiometric fluorescence, luminescence or photometric detection
  • Optimized cell-based GPCR assay platforms
  • Versatile reagents—GPCR cell lines, frozen and ready-to-use cells, ligands and radioligands, and cloned receptor membranes

For research use only. Not for use in diagnostic procedures.

GPCR Research Solutions

GPCR Research Reagents

GPCR research remains a widely studied area in drug discovery. As the compl ...

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Microplate Readers

Performance, Versatility, and Reliability for Today’s Laboratory Needs As m ...

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PerkinElmer Signals Screening

Signals Screening is an intuitive, configurable, and flexible screening wor ...

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Featured Products

EnVision 2105 Multimode Plate Reader

The EnVision® 2105 multimode plate reader provides exceptional speed, ultra ...

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LANCE cAMP Detection Kit, 500 assay points

LANCE® TR-FRET cAMP assay kit, for Gs- and Gi-coupled GPCR functional assay ...

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CGRP (human), [125I]-, 10µCi

Calcitonin gene-related peptide (CGRP), labeled with 125I. CGRP binds calci ...

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cAMPZen Frozen cells, Adrenergic α2A, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding ...

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Explore other Therapeutic Target Areas

Biomarker Detection

Biomarker detection has become an integral part of both disease detection a ...

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Cell Signaling Analysis

From receptor ligand binding to intracellular pathway analysis of phosphory ...

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Epigenetic Research

The study of gene expression is opening new doors for drug discovery. Our e ...

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Protein Kinase Research

Protein kinases are key focus targets in drug discovery. Kinases regulate m ...

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Protein-Protein Interaction Research

Protein-protein interaction research is uncovering new targets for drug dis ...

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Contact us to see how we can help you unlock the door to the next targeted therapy