G-protein coupled receptors (GPCR) are prominent targets in drug discovery. GPCRs are involved in most cellular responses to hormones and neurotransmitters and are essential for intracellular communication. Today, GPCR targeted drugs make up over a third of all approved drugs.
While GPCRs have been studied for decades, the complexities of these receptors in signaling are still being elucidated. As we better understand the role of GPCRs in different signaling pathways, such pathways are increasingly exploited for more targeted therapies, with fewer unwanted side effects.
PerkinElmer offers a variety of products to support GPCR research – for both functional and binding assays.
For research use only. Not for use in diagnostic procedures.