PerkinElmer

Fluorescent Agents

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Our portfolio of Targeted, Activatable, and Vascular fluorescent agents for imaging utilizes optimized in vivo chemistries and diverse mechanisms of action to deliver breakthrough imaging data on biological targets, pathways and processes - in the context of the living system.

 

Benefits of PerkinElmer Fluorescent Agents:

  • Biological, functional and physiological information
  • Easily applied to standard animal models
  • Versatile
    • use for simultaneous monitoring of multiple molecular processes
    • custom-design a fluorescent agent using PerkinElmer tags and/or nanoparticles
  • Designed and optimized for translational in vivo imaging narrow spectrally-separated excitation/emission spectra in the NIR region
  • High fluorescence efficiency (quantum yield)
  • Biocompatible, biodegradable and excretable
  • Chemical and photo-stability in vivo
  • Compatible with a variety of in vivo imaging systems
  • Developed and optimized on PerkinElmer's optical imaging platforms

 

 

For research use only. Not for use in diagnostic procedures.

 

Products & Services (33)
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Therapeutic Area
  • Angiogenesis (8)
  • Arthritis (12)
  • Atherosclerosis (11)
  • Bacterial infection (4)
  • Inflammation (12)
  • Oncology/Cancer (19)
  • Vascular disease (3)
Product Brand Name
  • BacteriSense (1)
  • BombesinRSense (1)
  • Cat B FAST (2)
  • Cat K FAST (1)
  • FolateRSense (1)
  • GastroSense (1)
  • Genhance (4)
  • GFR-Vivo (1)
  • HypoxiSense (1)
  • IntegriSense (3)
  • MMPSense (1)
  • OsteoSense (1)
  • ProSense (1)
  • ReninSense (1)
  • Superhance (1)
  • TLectinSense (1)
  • Transferrin-Vivo (1)
  • XenoLight (6)
Fluorescent Agent Type
  • Activatable (7)
  • Targeted (18)
  • Vascular (8)
Imaging Modality
  • Fluorescence (32)

1-25 of 33 Products & Services

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  • In vivo Fluorescent Agents

    AngioSense Fluorescent Imaging Agent

    In vivo optical imaging of vascular changes and vascular leak is an emerging modality for studying altered physiology in a variety of different cancers and inflammatory states. In oncology, increases in tumor vascular permeability can be an early indicator of tumor angiogenesis. In inflammatory disease increased vascular permeability can indicate alterations in fluid homeostasis in an acute edema response or in chronic organ conditions.

    PerkinElmer’s AngioSense® NIR fluorescent probes are designed to evaluate vascular changes to better understand various disease states or provide valuable information on effects of drug candidates earlier in the development process.

    List Price : 601.00 USD
  • RediJect Probe Standard Kit

    RediJect Bacterial Detection Fluorescent Imaging Probe (Standard kit)

    XenoLight RediJect Bacterial Detection Probe is a near-infrared (NIR) fluorescent agent for in vivo targeting of both Gram-positive and Gram-negative bacterial infections. 
    List Price : 490.00 USD
  • In vivo Fluorescent Agents

    TLectinSense 680 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 631.00 USD
  • In vivo Fluorescent Agents

    MMPSense Fluorescent Imaging Agent

    Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

    PerkinElmer’s MMPSense NIR activatable fluorescence agents are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

    List Price : 731.00 USD
  • RediJect 2-DG Fluorescent Imaging Probe (Explorer kit)

    XenoLight RediJect 2-DeoxyGlucosone (DG) 750 is a fluorescent imaging probe for in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, the probe has been designed to contain four 2-DG molecules per dye molecule. 
    List Price : 155.00 USD
  • In vivo Fluorescent Agents

    HypoxiSense 680 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 619.00 USD
  • RediJect Probe Explorer Kit

    RediJect Bacterial Detection Fluorescent Imaging Probe (Explorer Kit)

    XenoLight RediJect Bacterial Detection Probe is a near-infrared (NIR) fluorescent agent for in vivo targeting of both Gram-positive and Gram-negative bacterial infections. 
    List Price : 154.00 USD
  • In vivo Fluorescent Agents

    Transferrin-Vivo 750

    Transferrin is an important serum protein that mediates iron transport into cells via the transferrin receptor, a function that is essential for cell growth and metabolism. PerkinElmer’s Transferrin-Vivo 750 fluorescent probe is a NIR-labeled in vivo imaging agent that detects transferrin receptor levels associated with an altered metabolic need for iron in cancer and inflammatory cells. Transferrin-Vivo 750 fluorescent agent can also detect normal transferrin receptor levels in the liver as well as decreased expression due to altered iron metabolism associated with drug-induced liver injury.
    List Price : 631.00 USD
  • In vivo Fluorescent Agents

    GastroSense 750 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 601.00 USD
  • In vivo Fluorescent Agents

    ProSense Fluorescent Imaging Agent

    Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time. PerkinElmer’s ProSense® imaging agents are protease activatable NIR fluorescent probes that are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation. ProSense is available in 3 formats; 680, 750 EX, and 750 FAST.
    Price Range : 601.00 USD - 710.00 USD
  • In vivo Fluorescent Agents

    Genhance 680 Fluorescent Imaging Agent (1mg)

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 180.00 USD
  • In vivo Fluorescent Agents

    OsteoSense Fluorescent Imaging Agents

    Image and quantify osteoporosis, arthritis, cancer metastases, and other bone diseases, as well as normal bone growth and resorption, in vivo with OsteoSense® Fluorescent Imaging probes. As opposed to other imaging modalities such as CT or x-ray which raise the risk of harmful irradiation to the subject, in vivo fluorescence imaging offers no radiation exposure concerns, and when performed with optimized hydroxyapatite-targeted probes such as OsteoSense, can image and quantify bone growth and elucidate the biology of bone remodeling.

    OsteoSense is available in 3 wavelengths: 680, 750, and 800.

    List Price : 607.00 USD
  • In vivo Fluorescent Agents

    IntegriSense 750 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 717.00 USD
  • RediJect 2-DG Fluorescent Imaging Probe (Standard kit)

    XenoLight RediJect 2-DeoxyGlucosone (DG) 750 is a fluorescent imaging probe for in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, the probe has been designed to contain four 2-DG molecules per dye molecule.  
    List Price : 495.00 USD
  • In vivo Fluorescent Agents

    GFR-Vivo 680 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 454.00 USD
  • In vivo Fluorescent Agents

    Genhance 680 Fluorescent Imaging Agent (5mg)

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 683.00 USD
  • RediJect Control Kit

    RediJect 2-DG Fluorescent Imaging Probe (Control Dye)

    RediJect 2-DG control dye is a non-reactive dye that can be used as a negative control when using the RediJect 2-DG-750 fluorescent imaging probe. For laboratory use only. This product is intended for animal research only and not for use in humans. 
    List Price : 157.00 USD
  • In vivo Fluorescent Agents

    FolateRSense 680 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 625.00 USD
  • In vivo Fluorescent Agents

    Cat K 680 FAST Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.  
    List Price : 731.00 USD
  • In vivo Fluorescent Agents

    Cat B 750 FAST Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.  
    List Price : 745.00 USD
  • In vivo Fluorescent Agents

    Neutrophil Elastase 680 FAST Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 710.00 USD
  • RediJect Control Kit

    RediJect Bacterial Detection Fluorescent Imaging Probe (Control Dye)

    XenoLight RediJect Bacterial Detection control dye is a non-reactive dye that can be used as a negative control when using the RediJect Bacterial Detection 750 fluorescent imaging probe. 
    List Price : 154.00 USD
  • In vivo Fluorescent Agents

    ReninSense 680 FAST Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 745.00 USD
  • In vivo Fluorescent Agents

    Genhance 750 Fluorescent Imaging Agent (1mg)

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 180.00 USD
  • In vivo Fluorescent Agents

    Superhance 680 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 631.00 USD
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