PerkinElmer

Epigenetics Research

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The study of gene expression is opening new doors for drug discovery. Our epigenetics solutions include cellular detection kits and epigenetic assays for readers, writers, and erasers – allowing you to characterize multiple targets, shorten assay development time, and accelerate drug discovery.

Benefits of epigenetics kits and assays include:

  • Flexibility: Work with peptide or full-length protein substrates, or endogenous histones in biochemical or cell-based format
  • Sensitivity: Robust and reproducible detection, even at low enzyme concentrations
  • Specificity: Reagents highly specific for the mark of interest
  • Simplicity: One-well, no-wash assay platforms amenable to automation and HTS
  • Validated: Detailed, ready-to-use protocols for over 30 epigenetic enzyme assays

Drugs that can alter cellular traits have particular importance for conditions related to epigenetic modification, including cancer, mental illness, and heart disease. As knowledge of gene expression in disease states advances, so too does the possibility for epigenetic drugs.

Whether you need an epigenetics kit or validated assay, our suite of epigenetics research reagents offers a faster, more efficient path in the race to identify promising epigenetic drug candidates.

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Product Type
  • Instruments (5)
  • Reagents (103)
  • Services (1)
Antibody Conjugates
  • Anti-acetyl-lysine (1)
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  • Anti-H3 (C-term) (1)
  • Anti-H3K27ac (2)
  • Anti-H3K27me2 (1)
  • Anti-H3K27me2-1 (1)
  • Anti-H3K27me3 (2)
  • Anti-H3K36me2 (2)
  • Anti-H3K4 (3)
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  • Anti-H3K9/K27 (1)
  • Anti-H3K9ac (2)
  • Anti-H3K9me2 (2)
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  • Anti-H4K20me1 (1)
  • Anti-H4R3me (2)
  • Anti-methyl arginine (1)
  • Anti-methyl-Arg (1)
  • Anti-O-GlcNAc (1)
  • Anti-O-linked-GlcNAc (1)
  • Anti-p53K382ac (2)
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  • Epigenetics (49)
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  • Molecular Biology (41)
  • Protein Analysis & Detection (6)
  • Protein-protein interactions (7)
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  • Histone H2A (1)
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  • Histone H4 (1)
Assay Target Class
  • Histone (11)
Automation Compatible
  • Yes (59)
Buffer
  • Tricine (18)
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Concentration
  • 10 mCi/mL (22)
  • 20 mCi/mL (2)
  • 40 mCi/mL (1)
  • 5 mCi/mL (2)
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  • Time-Resolved Fluorescence (TRF) (24)
  • TR-FRET (15)
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  • In vitro (54)
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  • Eu-N1 (1)
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  • Eu-W1024 (14)
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Format
  • Microplates (55)
Label Position
  • alpha (30)
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Molecular Modification
  • Acetylation (12)
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  • Alpha (1)
  • AlphaLISA (35)
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Radionuclide
  • 32P (40)
Radioisotope
  • P-32 (41)
Sample Type
  • Enzyme (3)
Target Species
  • Human (1)
Therapeutic Area
  • Epigenetics (11)

"Epigenetics Research" 1-50 of 109 Products and Services

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VICTOR Multilabel Plate Reader

The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
EnSpire Alpha Plate Reader

EnSpire Alpha Plate Reader

The EnSpire Alpha Plate Reader provides proven Alpha technology to your lab at an affordable price and from the Alpha detection leader.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

ViewLux uHTS Microplate Imager

ViewLux uHTS Microplate Imager

The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

EnVision 2105 multimode plate reader

EnVision 2105 Multimode Plate Reader

The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

EnSpire Alpha Plate Reader

EnSpire Multimode Plate Reader

EnSpire® Multimode Plate Reader is designed to meet the demands of multi-user research environments, providing high performance technology and flexibility for a range of applications without compromising sensitivity. Combine this with our expertise and portfolio of reagents, PerkinElmer offers an unrivaled solution to your application needs.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

AlphaLISA Anti-methyl Histone H3 Arginine 2 (H3R2me) Acceptor Beads

AlphaLISA® Acceptor beads conjugated to an antibody against human Histone H3 that is methylated at arginine 2 (H3R2me). These beads can be used for AlphaLISA no-wash epigenetic writer and eraser assays.
Price Range : 1420.00 USD - 25900.00 USD

DELFIA Eu-N1 ITC chelate & Eu standard, 1 mg

DELFIA® Europium labeling chelate and Europium standard for labeling your own biomolecules for use in DELFIA time-resolved fluorescence assays. The ITC chelate reacts with free amine groups in the target biomolecule.
List Price : 2138.00 USD
Adenosine 5 Triphosphate 250 µCi

dTTP, [α-32P]- 3000Ci/mmol 10mCi/ml Lead, 250 µCi

Thymidine triphosphate (deoxythymidine triphosphate), labeled on the alpha phosphate group with 32P.
List Price : 647.00 USD

AlphaLISA Anti-unmodified Histone H3 Lysine 4 (H3K4) Acceptor Beads

AlphaLISA® Acceptor beads conjugated to an antibody against human histone H3 unmodified against lysine 4 (H3K4). These beads can be used for no-wash AlphaLISA epigenetic eraser assays.
Price Range : 1420.00 USD - 25900.00 USD

LANCE Ultra Europium-anti-di-methyl-Histone H3 Lysine 36 (H3K36me2) Antibody

Europium-labeled monoclonal antibody recognizing human Histone H3 di-methylated at lysine 36 (H3K36me2). For use in LANCE® Ultra epigenetic writer and eraser assays.
Price Range : 3552.00 USD - 8700.00 USD

Anti-acetyl-Histone H3 Lysine 9 (H3K9ac) AlphaLISA® Acceptor Beads

AlphaLISA® Acceptor beads conjugated to an antibody against human histone H3 acetylated at lysine 9 (H3K9Ac). These beads can be used for no-wash AlphaLISA epigenetic writer and eraser assays.
Price Range : 1478.00 USD - 26900.00 USD

dATP, [α-32P]- 6000Ci/mmol 20mCi/ml EasyTide

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 32P.
Price Range : 501.00 USD - 1148.00 USD
AlphaLISA Cellular Epigenetics kits

AlphaLISA Di-Methyl-Histone H3 Lysine 4 (H3K4me2) Cellular Detection Kit

This kit is designed for the detection of di-methylated Histone H3 Lysine 4 (H3K4me2) in cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 695.00 USD - 12400.00 USD
AlphaLISA Cellular Epigenetics kits

AlphaLISA dimethylated-Histone H3 Lysine 79 (H3K79me2) Cellular Detection Kit

This kit is designed for the detection of di-methylated Histone H3 Lysine 79 (H3K79me2) in cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 695.00 USD - 12400.00 USD

AlphaLISA Anti-unmodified Histone H3 Lysine 9/Lysine 27 (H3K9/K27) Acceptor Beads

AlphaLISA® Acceptor beads conjugated to an antibody against human Histone H3 that is unmodified at lysine 9 and lysine 27. These beads can be used for AlphaLISA no-wash epigenetic eraser assays.
Price Range : 1420.00 USD - 25900.00 USD
PerkinElmer

Histone 4 Acetylated Peptide, for LabChip EZ Reader

Fluorescently-labelled Histone 4 Peptide (Acetylated) for Epigenetic Assays (Enzyme inhibiton, target discovery, lead optimization)
List Price : 721.00 USD

LANCE Ultra Europium-anti-acetyl-Histone H3 Lysine 27 (H3K27ac) Antibody

Europium-labeled monoclonal antibody recognizing human Histone H3 acetylated at lysine 27 (H3K27ac). For use in LANCE® Ultra epigenetic writer and eraser assays.
Price Range : 3484.00 USD - 8700.00 USD

AlphaLISA Biotin-anti-Histone H4 Antibody

AlphaLISA® biotinylated monoclonal antibody recognizing the amino-terminal end of human histone H4. Broad species cross-reactivity is expected based on sequence similarity. This product is designed to be used with AlphaLISA® Epigenetics Acceptor beads to detect modified full-length histone H4 in homogeneous AlphaLISA assays.
Price Range : 1107.00 USD - 9900.00 USD

AlphaLISA Biotinylated Anti-Histone H3 (C-ter) Antibody

Biotinylated antibody against the C-terminal end of human histone H3, for use in Alpha no-wash epigenetic assays using full-length histone H3 as substrate.
Price Range : 1107.00 USD - 3920.00 USD

LANCE Ultra Europium-anti-methyl-Histone H3/H4 Arginine (H3/H4Rme pan) Antibody

Europium-labeled monoclonal antibody recognizing human Histone H3 and H4 methylated arginine residues. For use in LANCE® Ultra epigenetic writer and eraser assays.
Price Range : 3484.00 USD - 8700.00 USD
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA Tb-N1 Streptavidin

Terbium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
Price Range : 307.00 USD - 2092.00 USD

LANCE Ultra Europium-anti-acetyl-Histone H3 Lysine 9 (H3K9ac)

Europium-labeled monoclonal antibody recognizing human Histone H3 acetylated at lysine 9 (H3K9ac). For use in LANCE® Ultra epigenetic writer and eraser assays.
Price Range : 3484.00 USD - 8700.00 USD

AlphaLISA Anti-di/mono-methyl-Histone H3 Lysine 27 (H3K27me2-1) Acceptor Beads

AlphaLISA® Acceptor beads conjugated to an antibody against human histone H3 mono- or di-methylated at lysine 27 (H3K27me2-1). These beads can be used for no-wash AlphaLISA epigenetic writer and eraser assays.
Price Range : 1420.00 USD - 25900.00 USD
Adenosine 5 Triphosphate 250 µCi

dCTP, [α-32P]- 3000Ci/mmol 10mCi/ml Lead

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 32P.
Price Range : 396.00 USD - 916.00 USD

LANCE Ultra Europium-anti-O-linked-GlcNAc Antibody

Europium-labeled monoclonal antibody recognizing O-linked n-acetylglucosamine (O-linked GlcNAc). For use in LANCE® Ultra post-translational modification assays.
Price Range : 3484.00 USD - 8700.00 USD
PerkinElmer

p53 Acetylated Peptide, for LabChip EZ Reader

Fluorescently-labelled p53 Peptide (Acetylated) for Epigenetic Assays (Enzyme inhibiton, target discovery, lead optimization)
List Price : 721.00 USD
AlphaLISA Cellular Epigenetics kits

AlphaLISA di/mono-methylated-Histone H3 Lysine 27 (H3K27me2-1) Cellular Detection Kit

This kit is designed for the detection of di/mono-methylated Histone H3 Lysine 27 (H3K27me2-1) in cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 695.00 USD - 12400.00 USD
AlphaLISA Cellular Epigenetics kits

AlphaLISA Tri-Methyl-Histone H3 Lysine 27 (H3K27me3) Cellular Detection Kit

This kit is designed for the detection of tri-methylated Histone H3 Lysine 27 (H3K27me3) in cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 695.00 USD - 12400.00 USD
Adenosine 5 Triphosphate 250 µCi

UTP, [α-32P]- 3000Ci/mmol 10mCi/ml Lead

Uridine triphosphate, labeled on the alpha phosphate group with 32P.
Price Range : 565.00 USD - 1463.00 USD

AlphaLISA Anti-tri-methyl-Histone H3 Lysine 27 (H3K27me3) Acceptor Beads

AlphaLISA® Acceptor beads conjugated to an antibody against human histone H3 tri-methylated at lysine 27 (H3K27me3). These beads can be used for no-wash AlphaLISA epigenetic writer and eraser assays.
Price Range : 1420.00 USD - 25900.00 USD
PerkinElmer

AlphaLISA Cell-Histone Buffer Set

Pre-formulated buffer for cell-based Alpha epigenetic assays.
Price Range : 852.00 USD - 6700.00 USD
Adenosine 5 Triphosphate 250 µCi

PcP, [5`-32P]- 3000Ci/mmol 10mCi/ml Lead, 250 µCi

Cytidine 3', 5' bis(phosphate) (pCp) is labeled on the 5' phosphate group with 32P.
List Price : 1480.00 USD

ATP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide , 250 µCi

Adenosine triphosphate, labeled on the alpha phosphate group with 32P.
List Price : 540.00 USD
Adenosine 5 Triphosphate 250 µCi

NAD, [32P]- 800Ci/mmol 5mCi/ml

Nicotinamide Adenine Dinucleotide (NAD) 32P is labeled on the adenylate phosphate.
Price Range : 1745.00 USD - 4010.00 USD

LANCE Ultra Europium-anti-methyl-Histone H3 Lysine 9 (H3K9me2)

Europium-labeled monoclonal antibody recognizing human Histone H3 di-methylated at lysine 9 (H3K9me2). For use in LANCE® Ultra epigenetic writer and eraser assays.
Price Range : 3484.00 USD - 8700.00 USD
AlphaLISA Cellular Epigenetics kits

AlphaLISA dimethylated-Histone H3 Lysine 36 (H3K36me2) Cellular Detection Kit

This kit is designed for the detection of di-methylated Histone H3 Lysine 36 (H3K36me2) in cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 695.00 USD - 12400.00 USD

dCTP, [α-32P]- 800Ci/mmol 10mCi/ml EasyTide

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 32P.
List Price : 409.00 USD
Adenosine 5 Triphosphate 250 µCi

CTP, [α-32P]- 800Ci/mmol 10mCi/ml Lead, 250 µCi

Cytidine triphosphate, labeled on the alpha phosphate group with 32P
List Price : 434.00 USD

Anti-methyl-Histone H3 Lysine 9 (H3K9me2) AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to an antibody against human histone H3 di-methylated at lysine 9 (H3K9me2). These beads can be used for no-wash AlphaLISA epigenetic writer and eraser assays.
Price Range : 1420.00 USD - 25900.00 USD
AlphaLISA Cellular Epigenetics kits

AlphaLISA Total Histone H4 Cellular Detection Kit

The AlphaLISA® Total Histone H4 Cellular Detection Kit is designed for the detection of total human Histone H4 (modified and unmodified) in cell extracts or cells in culture medium, using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 2347.00 USD - 13400.00 USD
AlphaLISA Cellular Epigenetics kits

AlphaLISA Human Total Histone H2A Cell-based Assay Kit

AlphaLISA no-wash assay kit for the detection of total human Histone 2A (H2A) in cell extracts or cells in culture medium.
Price Range : 739.00 USD - 13800.00 USD

LANCE Ultra Europium-anti-unmodified Histone H3 Lysine 9/Lysine 27 (H3K9/K27) Antibody

Europium-labeled monoclonal antibody recognizing human Histone H3 that is unmodified at lysine 9 and lysine 27 (H3K9/K27). For use in LANCE® Ultra epigenetic writer and eraser assays.
Price Range : 3484.00 USD - 8700.00 USD

LANCE Ultra Europium-anti-acetyl-p53 Lysine 382 (p53K382ac) Antibody

Europium-labeled monoclonal antibody recognizing human p53 acetylated at lysine 382 (p53K382ac). For use in LANCE® Ultra epigenetic writer and eraser assays.
Price Range : 3484.00 USD - 8700.00 USD
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA Sm-N1 Streptavidin

Samarium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
Price Range : 307.00 USD - 2092.00 USD
Adenosine 5 Triphosphate 250 µCi

NAD, [32P]- 800Ci/mmol 5mCi/ml Lead

Nicotinamide Adenine Dinucleotide (NAD) 32P is labeled on the adenylate phosphate
Price Range : 1746.00 USD - 3892.00 USD

LANCE Ultra Europium-anti-acetyl-Histone H4 Lysine (H4Kac pan) Antibody

Europium-labeled monoclonal antibody recognizing human Histone H4 (H4Kac pan). For use in LANCE® Ultra epigenetic writer and eraser assays.
Price Range : 3484.00 USD - 8700.00 USD
PerkinElmer

HDAC (Histone Deacylase) Substrate B, for LabChip EZ Reader

Fluorescently-labelled Substrate A peptide (Acetylated) for Epigenetic Assays (Enzyme inhibiton, target discovery, lead optimization)
List Price : 700.00 USD

ATP, [γ-32P]- 3000Ci/mmol 10mCi/ml EasyTide

Adenosine triphosphate, labeled on the gamma phosphate group with 32P.
Price Range : 379.00 USD - 876.00 USD

UTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide

Uridine triphosphate, labeled on the alpha phosphate group with 32P.
Price Range : 540.00 USD - 1500.00 USD

dGTP, [α-32P]- 6000Ci/mmol 20mCi/ml EasyTide, 500 µCi

Deoxyguanosine triphosphate, labeled on the alpha phosphate group with 32P.
List Price : 871.00 USD

"Epigenetics Research" 1-50 of 109 Products and Services

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