Enzymology

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Find the end-point and real-time kinetic reagents and instruments you need for your enzymatic assays. We offer:

Radiolabeled substrates for highly-sensitive kinetic assays and antibody-free screening
TR-FRET, TRF, and Alpha no-wash technologies for fast and simple measurement of biochemical and cellular enzymatic activity
Microfluidic mobility-shift assays (MSA) for radiometric analysis of substrate conversion, kinetics, and mechanism-of-action
Multi-mode plate readers for maximal speed and throughput independent of technology platform

Products & Services (298)
Technical Resources (324)
Tools & More (13)
Business Insights (0)

Products & Services (298)

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Consumables (2)
Instruments (1)
Reagents (295)

Assay Target

4EBP1 (3)
Acetyl CoA carboxylase (1)
Akt1 (6)
Akt1/2 (1)
Akt1/2/3 (7)
ALK (2)
AMPKα (2)
ATF1 (1)
ATF2 (1)
BAD (2)
BTK (2)
c-Jun (2)
c-Met (2)
Caspase-9 (1)
Chk-1 (1)
Chk-2 (1)
Cofilin (1)
CREB (2)
EGFR (6)
eIF2α (2)
eIF4E (2)
Elk1 (1)
ErbB2 (1)
ERK1/2 (4)
GAPDH (2)
GSK3α (1)
GSK3β (2)
Histone H2A (1)
Histone H3 (10)
Hsp27 (1)
IKKα (3)
INSR (2)
IκBα (1)
JNK1/2/3 (2)
JNK1/3 (1)
LCK (1)
MEK1 (2)
MKK3/6 (1)
MKK4 (3)
mTOR (2)
NFκB (5)
p38 MAPK (1)
p53 (2)
p70 S6K (5)
PDK1 (1)
S6RP (3)
SHP-1 (2)
SHP-2 (3)
SLP-76 (4)
SMAD1 (3)
SMAD2 (3)
SMAD3 (3)
Src (2)
STAT1 (3)
STAT3 (5)
STAT4 (1)
STAT5 (3)
STAT6 (1)
SYK (3)
TBK1 (1)
Topo IIα (2)
TREM2 (1)
VEGF2 Receptor (3)
VEGFR2 (2)
Zap70 (4)
β-Catenin (1)

Target Species

Human (101)

Application

Drug Discovery & Development (3)
Epigenetics (46)
Kinase (175)
Mobility Shift (36)
Protein Analysis & Detection (126)

Therapeutic Area

Epigenetics (10)

Product Brand Name

AlphaLISA (31)
AlphaLISA SureFire Ultra (57)
AlphaPlex (1)
AlphaScreen (3)
AlphaScreen SureFire (58)
DELFIA (5)
LabChip EZ Reader (50)
LANCE (5)
LANCE Ultra (30)
LANCE Ultra (50)
SPA Enzymatic Assays (3)

Detection Method

Alpha (147)
DELFIA TRF (5)
Fluorescence (1)
Radiometric (4)
Time-Resolved Fluorescence (TRF) (93)
TR-FRET (88)

Molecular Modification

Acetylation (12)
GlcNAc (1)
Glycosidation (1)
Methylation (25)
Phosphorylation (107)
Total (1)
Unmodified (4)

Sample Type

Enzyme (38)

Antibody Conjugates

Anti-acetyl-lysine (1)
Anti-Acetyl-Lysine (1)
Anti-H3 (C-term) (1)
Anti-H3K27ac (2)
Anti-H3K27me2 (1)
Anti-H3K27me2-1 (1)
Anti-H3K27me3 (2)
Anti-H3K36me2 (2)
Anti-H3K4 (3)
Anti-H3K4me1-2 (2)
Anti-H3K9/H3K27 (1)
Anti-H3K9/K27 (1)
Anti-H3K9ac (2)
Anti-H3K9me2 (2)
Anti-H3R2me (1)
Anti-H4K20me1 (1)
Anti-H4R3me (2)
Anti-methyl arginine (1)
Anti-methyl-Arg (1)
Anti-O-GlcNAc (1)
Anti-O-linked-GlcNAc (1)
Anti-P-Ser 14-3-3 (1)
Anti-P-Tyr-100 (1)
Anti-p53K382ac (2)
Anti-phospho-4EBP1 (1)
Anti-phospho-Acetyl-CoA-Carboxylase (1)
Anti-phospho-Crosstide (1)
Anti-phospho-glycogen synthase (1)
Anti-phospho-Histone H3 (2)
Anti-phospho-I?Ba (1)
Anti-phospho-MEK1/2 (1)
Anti-phospho-p70S6K (1)
Anti-phospho-PKC (1)
Anti-phospho-PLK (1)
Anti-phospho-rpS6 (1)
Anti-phospho-serine (1)
Anti-phospho-threonine (2)
Anti-phospho-Topo IIa (1)
Anti-phospho-Tyrosine Hydroxylase (1)
P-Tyr-100 (1)
PT66 (2)
PY20 (2)
Streptavidin/Phosphosensor (1)
Streptavidin/PT66 (1)
Streptavidin/PY20 (1)

Radioisotope

H-3 (3)

Fluorophore

Eu-N1 (5)
Eu-W1024 (37)
ULight (18)

Assay Points (200-50,000)

100 (51)
1000 (1)
10000 (129)
500 (135)
5000 (14)
50000 (103)

Assay Target Class

Histone (10)
Phosphoprotein (113)
Protein (30)

Automation Compatible

Yes (233)

Experimental Type

In vitro (162)

Format

Microplates (176)

1-12 of 298 Products & Services

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EZ READER, SHIP LEVEL

122919

The EZ Reader can help to save time and money in your laboratory by identifying the most promising lead candidates faster.

The EZ Reader instrument is available outside the EU. Please contact your local representative for further information.
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LANCE Ultra Europium-anti-methyl-Histone H3/H4 Arginine (H3/H4Rme pan) Antibody

TRF0415-M , TRF0415-D

Europium-labeled monoclonal antibody recognizing human Histone H3 and H4 methylated arginine residues. For use in LANCE® Ultra epigenetic writer and eraser assays.

Price Range : 3632.00 USD - 9100.00 USD
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AlphaScreen SureFire Phospho-ATF2 (Thr71) Assay Kit

TGRAF2S500 , TGRAF2S10K , TGRAF2S50K

The AlphaScreen^® SureFire^® p-ATF2 (Thr71) assay is a sandwich immunoassay for quantitative detection of phospho-ATF2 (phosphorylated on Thr71) in cellular lysates using Alpha Technology. Please note that an AlphaScreen Protein A kit, which contains the Alpha Beads necessary to run this assay, needs to be purchased separately in addition to the AlphaScreen SureFire kit.

Price Range : 1538.00 USD - 16600.00 USD
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AlphaLISA Acetylated Histone H3 Lysine 9 (H3K9ac) Cellular Detection Kit

AL714C , AL714F , AL714HV

This kit is designed for the detection of acetylated Histone H3 Lysine 9 (H3K9ac) in cell lysates using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 725.00 USD - 12900.00 USD
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AlphaLISA di/mono-methylated-Histone H3 Lysine 27 (H3K27me2-1) Cellular Detection Kit

AL721C , AL721HV , AL721F

This kit is designed for the detection of di/mono-methylated Histone H3 Lysine 27 (H3K27me2-1) in cell lysates using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 725.00 USD - 12900.00 USD
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LANCE Ultra Europium anti-phospho-Glycogen Synthase (Ser641)

TRF0220-D , TRF0220-M

Europium-labeled rabbit polyclonal antibody recognizing human Muscle Glycogen Synthase phosphorylated at Ser641. Antibody labeled with the LANCE^® Eu-W1024-ITC chelate. Sequence motif recognized: PApSVPPSPSL

Price Range : 2482.00 USD - 7400.00 USD
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ProfilerPro Kinase Peptide Substrate 22, for LabChip EZ Reader

760366

Fluorescently-labelled peptide substrate 22 for kinase assays (inhibiton, target discovery, lead optimization)

List Price : 757.00 USD
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AlphaScreen SureFire ALK (p-Tyr1604) Assay Kit

TGRAL2S500 , TGRAL2S50K , TGRAL2S10K

The AlphaScreen^® SureFire^® p-ALK (Tyr1604) assay is a sandwich immunoassay for quantitative detection of phospho-ALK (phosphorylated on Tyr1604) in cellular lysates using Alpha Technology. Please note that an AlphaScreen Protein A kit, which contains the Alpha Beads necessary to run this assay, needs to be purchased separately in addition to the AlphaScreen SureFire kit.

Price Range : 1538.00 USD - 16600.00 USD
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Phospho-ERK 1/2 (Thr202/Tyr204) LANCE Ultra TR-FRET Cellular Detection Kit

TRF4000C , TRF4000M

LANCE Ultra phospho-ERK 1/2 (Thr202/Tyr204) kits are designed for the detection of phosphorylated ERK 1 and ERK2 in cell lysates using a simple, homogeneous LANCE Ultra assay (no wash steps). This assay is compatible with both adherent and suspension cells.

Price Range : 1512.00 USD - 6800.00 USD
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LANCE® Eu-W1024 Anti-phosphotyrosine (P-Tyr-100)

AD0161 , AD0203 , AD0162

Europium-labeled anti-phosphotyrosine (P-Tyr-100) antibody, for use in LANCE® TR-FRET kinase assays.

Price Range : 224.00 USD - 10200.00 USD
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AlphaLISA Di-Methyl-Histone H3 Lysine 4 (H3K4me2) Cellular Detection Kit

AL716HV , AL716F , AL716C

This kit is designed for the detection of di-methylated Histone H3 Lysine 4 (H3K4me2) in cell lysates using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 725.00 USD - 12900.00 USD
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AlphaLISA Acetylated-Histone H3 Lysine 27 (H3K27ac) Cellular Detection Kit

AL720HV , AL720F , AL720C

This kit is designed for the detection of acetylated Histone H3 Lysine 27 (H3K27ac) in cell lysates using a homogeneous AlphaLISA assay (no wash steps).

Price Range : 725.00 USD - 12900.00 USD

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