Drug discovery starts with an understanding of the basics of diseases and disease pathways. Throughout the process of unraveling the complexity of disease pathways, identifying and characterizing targets, high throughput screening, and lead optimization PerkinElmer has the assays you can count on.
PerkinElmer's drug discovery reagents cover a wide array of applications ranging from immunoassays platforms and kinase assays to reporter gene, cytotoxicity and cell proliferation assays. Our easy-to-use platforms provide greater sensitivity, wide dynamic range, and reduced background.
From basic science to high throughput screening and lead optimization, PerkinElmer drug discovery reagents provide easy-to-use next generation assays every step of the way.
Alpha Technology
Alpha is a homogeneous, bead-based assay platform offering several advantages over traditional ELISAs. This versatile, easy-to-use platform is suitable for a wide range of applications.
AlphaLISA®, AlphaLISA SureFire® Ultra™, Alpha Screen®, AlphaPlex®, and Alpha kits and standalone reagents can be used to detect:
TR-FRET Technology
TR-FRET combines the benefits of Time Resolved Fluorescence (TRF) with those of Forster Resonance Energy Transfer (FRET). PerkinElmer offers two TR-FRET technologies - HTRF® (Homogeneous Time Resolved Technology) and LANCE® (Lanthanide Chelate Excite) Ultra™ TR-FRET.
HTRF and LANCE Ultra kits and standalone reagents can be used to detect:
TRF Technology
DELFIA® (Dissociation-Enhanced Lanthanide Fluorescence Immunoassay) is a washed based, time-resolved fluorescence (TRF) detection platform that utilizes fluorescent lanthanide chelates rather than other fluorophores. While superficially quite similar to an ELISA, DELFIA® comes with additional benefits. DELFIA® has a stable, time-resolved fluorescent signal which improves the assay dynamic range.
DELFIA® kits and standalone reagents can be used to detect:
Luminescence Assays
Luminescence assays are used throughout the drug discovery workflow. Our assays are provided a simple, easy-to-use microplate format.
Our luminescence assays include:
Receptor Cell Lines & Membranes
Whether you are working with cell-based or biochemical assays, our GPCR overexpressing cell lines and membranes originate from clones carefully selected to produce the most effective assays.
Our cell line clones have been selected to produce the most effective:
Radiometric Assays
Radiometric detection remains the most sensitive assay today. We offer scintillation proximity assays (SPAs) and radiolabeled ligands for ligand binding studies, plus a vast array of radiochemicals for all your research needs.
Our products support a range of radiometric assays, including:
PerkinElmer R&D scientists focus on developing fully validated, ready-to-use kits and reagents for the hottest new targets. We continue to evolve our product offering as your science evolves.
Our Alpha, HTRF®, LANCE® Ultra™ TR-FRET, and DELFIA® TRF technologies offer alternatives to standard ELISA assays, each with a larger dynamic range and higher signal-to-noise ratio. Alpha, HTRF and LANCE Ultra TR-FRET have the added advantage of having no wash or separation steps, saving you valuable time.
PerkinElmer offers a range of ELISA alternative immunoassay technologies that enable selection of the optimal immunoassay platform for your requirements. From sample compatibility to sample volume, throughput, detectable range, signal window, signal stability, reproducibility, automation compatibility, and desired speed of results, PerkinElmer offers immunoassay technology platforms, pre-configured kits, and customizable reagents for superior results.
Better Microplates Means Better Results
A microplate is a critical part of your discovery process. Microplates have the capability to generate valuable, information-rich data that bring great insights into discovery screening.
Microplate planarity and inaccurate data collection are common issues caused by microplates that are not carefully designed for the unique challenges of sample screening which can result in missed data points, sample re-screening, missed project timelines, and ultimately higher costs.
PerkinElmer offers a family of plate readers focused on performance, versatility, and reliability for today's laboratory needs. Our drug discovery reagents are validated using our microplate readers, ensuring optimal performance when used together.
Are you working on a novel target? Need to develop an assay? We’re here to help. Choose between custom labeling or custom assay development. Let our experts
