PerkinElmer

cfDNA Isolation and Analysis Reagents

PerkinElmer has a complete portfolio of solutions for the isolation and analysis of cell-free DNA to address all laboratory needs.

For research use only. Not for use in diagnostic procedures.

Vanadis® cfDNA Platform Reagents & Consumables

The Vanadis platform is a highly automated non-PCR, non-NGS based cell-free DNA analysis platform enabling cost-effective quantification of targeted chromosomes. Vanadis reagents and consumables were optimized to streamline the workflow and improve your lab efficiency.

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Isolation of cfDNA from Fresh and Frozen Plasma

The isolation of cfDNA is a huge challenge due to low concentrations, instability, and small fragment sizes of 50 - 200 bp and therefore precise and reliable cfDNA purification workflows are required. Based on the unique chemagen Technology using M-PVA Magnetic Beads, PerkinElmer has developed the chemagic™ cfDNA kits to isolate cfDNA from 0.5 - 5 ml fresh and frozen plasma derived from EDTA, citrate or other common collection tubes with minimal hands-on time using the chemagic instruments.

The automated sample processing by the chemagic instruments excludes cross contamination and ensures safe handling of infectious sample material.

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Manual isolation of cfDNA from Serum and Plasma

Designed for the enrichment of cfDNA from plasma and serum, the NextPrep-Mag cfDNA Kit efficiently isolates cfDNA while reducing gDNA contamination. The NextPrep-Mag cfDNA Kit is a manual, magnetic bead-based kit ideal for isolating cfDNA from 1 - 5 mL human plasma or serum with a 1.5-hour protocol.

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Fast cfDNA Extraction from Urine

The NextPrep-Mag Urine cfDNA Isolation kit is designed for extracting cell-free DNA (cfDNA) for constructing NGS libraries from urine, using a fast, magnetic bead-based format requiring minimal hands-on time. The isolation procedure, which can be completed in approximately 30 minutes, includes an initial lysis and DNA binding step, wash steps, and elution of cfDNA from the magnetic beads.

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Library Prep Optimized for Low Input cfDNA samples

The NEXTFLEX® Cell Free DNA-Seq Kit 2.0 can produce libraries from 10 ng of cell free DNA in only two hours. This low-input library preparation kit delivers high coverage quality and reduced bias for Illumina® sequencing applications.

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