PerkinElmer

Biotherapeutics Research

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Biotherapeutics allow researchers to explore new mechanisms for the treatment of a variety of conditions. Our biotherapeutics research products are designed for consistent and reproducible results, and are a component of GLP-compliant processes in the world's leading pharmaceutical, biotechnology and contract research organizations.

Effective biotherapeutic workflows make use of our portfolio of assays and reagents, multimode plate readers, instrumentation, automation solutions, informatics, and technical expertise.

Our biotherapeutics products include:

  • LANCE® TR-FRET technology for Fc-receptor binding and isotyping
  • AlphaLISA® isotyping, Fc-receptor binding, and bioprocess contaminant detection kits
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Multimode plate readers
  • Cellular, tissue, and in vivo imaging systems

Accelerate the development and marketability of your biotherapeutic drugs while still meeting stringent regulatory demands. With our technology and guidance, numerous biotherapeutic drugs have been approved for the treatment of cancer, inflammatory disease, and several rare diseases.

For Research Use Only. Not for diagnostic procedures.

Target Identification
Target Identification

Target Identification

Identify relevant disease targets during the early stages of discovery for new biotherapeutics. Avoid latent failures downstream by thorough validation of each target. We provide the capability for the most accurate prediction of target relevance in human disease through a combination of in in vitro and in vivo approaches.
  • Cellular imaging for in vitro target validation
  • In vivo imaging for target discovery
  • Tissue imaging for ex vivo target validation
Protein Antibody
Protein Antibody

Cloning and Expression

We offer a range of microfluidic, ELISA-alternative, imaging, informatics, detection and automation solutions that simplify workflow and improve the quality of data generated at every stage in the cloning and expression process:
  • Clone Selection
  • Protein Purification
  • Functional Screening
  • Bioanalytical Characterization

Suggested Products

General laboratory
General laboratory

Safety and Preclinical

Accurately quantify anti-drug antibodies (ADA) and pharmacokinetics (PK) / pharmacodynamics (PD) through high quality, reproducible test data. Whether your research involves monoclonal antibodies (mAb) or proteins and peptides, our wide portfolio of immunogenicity, neutralizing antibody (NAb) and PD/PK testing solutions can streamline your workflow.
Pipetting
Pipetting

Manufacturing and QC

Identify process and product related impurities to ensure they do not compromise the quality or safety of your biotherapeutics or vaccine research.

LabChip® microfluidic technology provides rapid and reproducible purity analysis for therapeutic proteins and detection and visualization of low concentration impurity peaks down to 5 ng/µL accelerating manufacturing and QC processes.

Products & Services (156)
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Product Type
  • Accessories (33)
  • Consumables (9)
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  • Reagents (98)
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Assay Target
  • 4EBP1 (1)
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  • Fc (1)
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  • FCGR3A (8)
  • GSK3β (1)
  • IgA (2)
  • IgE (3)
  • IgG (9)
  • IgG1 (4)
  • IgG2 (2)
  • IgG2a (1)
  • IgG2b (1)
  • IgG3 (1)
  • IgG4 (1)
  • IgM (6)
  • JNK1/2/3 (1)
  • Kappa light chain (4)
  • MEK1 (2)
  • Pan Mouse IgG Fc (1)
  • Protein A (1)
  • Residual DNA (4)
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  • S6RP (1)
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  • STAT3 (1)
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  • VEGF2 Receptor (1)
Application
  • Antibody binding (2)
  • DNA/RNA Quantitation (1)
  • DNA/RNA Quantitation and QC (2)
  • Isotyping (9)
  • Kinase (7)
  • Protein Analysis (8)
  • Protein Analysis & Detection (80)
  • Protein-protein interactions (9)
Therapeutic Area
  • Biologics/Bioprocess (54)
  • Central Nervous System (2)
  • Metabolic (3)
Product Brand Name
  • AlphaLISA (57)
  • AlphaLISA SureFire Ultra (12)
  • DELFIA (1)
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  • LANCE Ultra (19)
  • Operetta (28)
  • Operetta CLS (1)
  • Operetta CLS AND Opera Phenix (7)
  • Victor (1)
Detection Method
  • Absorbance (3)
  • Alpha (71)
  • DELFIA TRF (1)
  • Fluorescence (4)
  • Fluorescence Polarization (2)
  • Image-based Cytometry (1)
  • Luminescence (3)
  • Time-Resolved Fluorescence (TRF) (22)
  • TR-FRET (18)
  • Transmission (1)
Sample Type
  • DNA / RNA (2)
  • Protein (10)
Antibody Conjugates
  • Anti-bovine IgG (1)
  • Anti-bovine IgG1 (1)
  • Anti-bovine IgG2 (1)
  • Anti-bovine IgM (1)
  • Anti-human IgE (1)
  • Anti-human IgG (2)
  • Anti-human IgG1 (1)
  • Anti-human IgG2 (1)
  • Anti-human IgG3 (1)
  • Anti-mouse IgE (1)
  • Anti-mouse IgG1 (1)
  • Anti-mouse IgG2a (1)
  • Anti-mouse IgG2b (1)
  • Anti-mouse IgG3 (1)
  • Anti-mouse IgM (1)
  • Human Fc-fragment (1)
Assay Points (200-50,000)
  • 100 (17)
  • 10000 (19)
  • 500 (40)
  • 5000 (21)
  • 50000 (9)
Assay Target Class
  • Antibody (35)
  • DNA (4)
  • Fc-receptor (12)
  • Peptide (1)
  • Phosphoprotein (7)
  • Protein (7)
Automation Compatible
  • Yes (89)
Depth
  • 33.0 in (2)
  • 49.0 cm (1)
Experimental Type
  • In vitro (76)
Format
  • Microplates (74)
Imaging Modality
  • High Content (1)
  • microCT Imaging (1)
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Length
  • 98.0 (1)
  • 98.0 cm (1)
Model Compatible With
  • LabChip GXII Touch 24 (1)
  • LabChip GXII Touch HT (1)
  • Opera Phenix Plus (1)
  • Operetta (29)
  • Operetta CLS AND Opera Phenix (8)
Type
  • High pI (7.0 - 9.0) (1)
  • Low pI (3.0 - 7.0) (1)

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1-25 of 156 Products & Services

  • Operetta CLS High-Content Analysis System

    Operetta CLS High-Content Analysis System

    Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
  • JANUS G3 Btx Pro-Plus

    JANUS G3 BioTx Pro Plus Workstation

    The JANUS® G3 Bio Tx Pro Plus offers full walk-away automation for high-throughput process development, enabling more data from precious starting materials and limited resources.
  • IVIS-SpectrumCT-Hero

    IVIS® SpectrumCT In Vivo Imaging System

    The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • Spectrum-CU-Hero

    IVIS Spectrum In Vivo Imaging System

    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • EnSight Multimode Plate Reader

    EnSight Multimode Plate Reader

    The EnSight multimode plate reader offers HTS Alpha, Ultra-sensitive Luminescence and fast well-imaging technologies alongside conventional multimode detection technologies. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina III In Vivo Imaging System

    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS In Vivo Imaging System

    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • LabChip GX GXII Touch Product

    LabChip GXII Touch Protein Characterization System

    The LabChip® GXII Touch protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Leveraging microfluidic electrophoretic separation technology, the LabChip® GXII Touch system enables rapid characterization with minimal sample preparation setup and sample input volume.
  • SpectrumBL-CU-Hero

    IVIS® SpectrumBL High-Throughput In Vivo Optical Imaging System

    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • JANUS G3 BioTx Pro Workstation

    JANUS G3 BioTX Pro Workstation

    The affordable and compact JANUS® G3 BioTx Pro Automated Workstation enables consistent, time-saving small-scale protein purification and sample preparation for analytical protein characterization required to support quality by design experimentation in both upstream and downstream processes.

    Ideal Workstation for:

    • Expression optimization
    • Cell line selection
    • Purification process development
    • Bioanalytical sample preparation
  • VictorX_ImageA_320px

    VICTOR Multilabel Plate Reader

    The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina LT In Vivo Imaging System

    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • EnVision 2105 multimode plate reader

    EnVision Multimode Plate Reader

    The EnVision® 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

    The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP).

  • AlphaLisa Analyte 2

    IgM (bovine), lyophilized (AlphaLISA)

    Bovine IgM standard, 10 µg, for use in AlphaLISA immunoassays. This vial contains enough analyte to run 10 standard curves. This standard is provided in the AlphaLISA bovine IgM kits, but can also be ordered separately.
    List Price : 420.00 USD
  • IgG2 (bovine) AlphaLISA Detection Kit

    The AlphaLISA immunoassay kit for detection and quantitation of bovine IgG2 in serum, plasma, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
    Price Range : 841.00 USD - 13500.00 USD
  • IgE (mouse) isotyping AlphaLISA Detection Kit

    This AlphaLISA® immunoassay kit enables the isotyping of mouse IgE antibodies in different sample matrices, including cell culture media. The IgE subtype plays a role in allergic reactions, parasitic infections and hypersensitivity reactions.
    Price Range : 871.00 USD - 12100.00 USD
  • PerkinElmer

    Kappa Light Chain (human), lyophilized (LANCE)

    Human kappa light chain standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human Kappa Light Chain Detection Kit, but can also be ordered separately.
    List Price : 305.00 USD
  • LANCE standard

    Biotinylated human FCGR3A (176Val) (LANCE)

    Biotinylated human FCGR3A/CD16a(176Val/V158) for use in LANCE Ultra TR-FRET Fc-receptor binding assays.
    List Price : 335.00 USD
  • Protein Reagent Kit

    ProteinEXact Assay Reagent Kit

    The LabChip® GXII Touch Capillary Electrophoresis System utilizes a microfluidic chip to rapidly characterize protein samples from 24-, 96- or 384-well plates. The technology automatically stains distains, electrophoretically separates and analyzes the protein samples. Use the system software to automatically analyze data which is immediately available for review or reporting in virtual gel, electropherogram graph or table summary form.
    List Price : 502.00 USD
  • LANCE Ultra Biomarker

    IgM (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human IgM Detection Kit is designed for detection and quantitation of human IgM in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 1625.00 USD - 10800.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-Mouse IgG3 (isotyping) AlphaLISA Acceptor beads

    AlphaLISA® Acceptor beads conjugated to a anti-mouse IgG3. This bead can be used to create no-wash AlphaLISA assays for isotyping and other applications.
    Price Range : 708.00 USD - 29000.00 USD
  • AlphaLisa Analyte 2

    IgG2 (bovine), lyophilized (AlphaLISA)

    Bovine IgG2 standard, 3 µg, for use in AlphaLISA immunoassays. This vial contains enough analyte to run 10 standard curves. This standard is provided in the AlphaLISA bovine IgG2 kits, but can also be ordered separately.
    List Price : 437.00 USD
  • LANCE Ultra Biomarker

    FCGR3A/CD16A (176Phe/F158) (human) LANCE Ultra TR-FRET Binding Kit

    This kit is designed for the quantitative determination of Human FCGR3A/CD16a (176Phe/F158) and human Fc fragment binding using a homogeneous (no wash) LANCE Ultra TR-FRET binding assay.
    Price Range : 877.00 USD - 11700.00 USD
  • Alpha Donor Bead Antibody Conjugated

    Anti-Human IgG Alpha Donor beads

    Alpha Donor beads conjugated to mouse anti-human IgG (Fc-specific) antibody. This bead can be used to capture human IgG antibodies containing an Fc-region for Alpha no-wash protein detection, Fc-receptor binding, antibody detection, antibody binding, and other applications.
    Price Range : 611.00 USD - 11000.00 USD
  • Host Cell Residual DNA AlphaLISA Detection Kit

    The AlphaLISA® Host Cell Residual DNA Detection Kit is designed for detection and quantitation of DNA contaminants in cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay. This kit can be used with DNA from different prokaryotic and eukaryotic species.
    Price Range : 871.00 USD - 12600.00 USD
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