PerkinElmer

Biotherapeutics Research

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Biotherapeutics allow researchers to explore new mechanisms for the treatment of a variety of conditions. Our biotherapeutics research products are designed for consistent and reproducible results, and are a component of GLP-compliant processes in the world's leading pharmaceutical, biotechnology and contract research organizations.

Effective biotherapeutic workflows make use of our portfolio of assays and reagents, multimode plate readers, instrumentation, automation solutions, informatics, and technical expertise.

Our biotherapeutics products include:

  • LANCE® TR-FRET technology for Fc-receptor binding and isotyping
  • AlphaLISA® isotyping, Fc-receptor binding, and bioprocess contaminant detection kits
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Multimode plate readers
  • Cellular, tissue, and in vivo imaging systems

Accelerate the development and marketability of your biotherapeutic drugs while still meeting stringent regulatory demands. With our technology and guidance, numerous biotherapeutic drugs have been approved for the treatment of cancer, inflammatory disease, and several rare diseases.

For Research Use Only. Not for diagnostic procedures.

Target Identification
Target Identification

Target Identification

Identify relevant disease targets during the early stages of discovery for new biotherapeutics. Avoid latent failures downstream by thorough validation of each target. We provide the capability for the most accurate prediction of target relevance in human disease through a combination of in in vitro and in vivo approaches.
  • Cellular imaging for in vitro target validation
  • In vivo imaging for target discovery
  • Tissue imaging for ex vivo target validation
Protein Antibody
Protein Antibody

Cloning and Expression

We offer a range of microfluidic, ELISA-alternative, imaging, informatics, detection and automation solutions that simplify workflow and improve the quality of data generated at every stage in the cloning and expression process:
  • Clone Selection
  • Protein Purification
  • Functional Screening
  • Bioanalytical Characterization

Suggested Products

General laboratory
General laboratory

Safety and Preclinical

Accurately quantify anti-drug antibodies (ADA) and pharmacokinetics (PK) / pharmacodynamics (PD) through high quality, reproducible test data. Whether your research involves monoclonal antibodies (mAb) or proteins and peptides, our wide portfolio of immunogenicity, neutralizing antibody (NAb) and PD/PK testing solutions can streamline your workflow.
Pipetting
Pipetting

Manufacturing and QC

Identify process and product related impurities to ensure they do not compromise the quality or safety of your biotherapeutics or vaccine research.

LabChip® microfluidic technology provides rapid and reproducible purity analysis for therapeutic proteins and detection and visualization of low concentration impurity peaks down to 5 ng/µL accelerating manufacturing and QC processes.

Products & Services (161)
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  • Accessories (33)
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Assay Target
  • 4EBP1 (1)
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  • IgG1 (4)
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  • IgG2a (1)
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  • IgM (6)
  • JNK1/2/3 (1)
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Application
  • Antibody binding (2)
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  • DNA/RNA Quantitation and QC (2)
  • Isotyping (10)
  • Kinase (7)
  • Protein Analysis (8)
  • Protein Analysis & Detection (82)
  • Protein-protein interactions (9)
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  • Biologics/Bioprocess (55)
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  • Alpha (2)
  • AlphaLISA (55)
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  • DELFIA (1)
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  • Operetta CLS AND Opera Phenix (7)
  • Victor (1)
Detection Method
  • Absorbance (3)
  • Alpha (73)
  • DELFIA TRF (1)
  • Fluorescence (4)
  • Fluorescence Polarization (2)
  • Image-based Cytometry (1)
  • Luminescence (3)
  • Time-Resolved Fluorescence (TRF) (22)
  • TR-FRET (18)
  • Transmission (1)
Sample Type
  • DNA / RNA (2)
  • Protein (9)
Antibody Conjugates
  • Anti-bovine IgG (1)
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  • Human Fc-fragment (1)
Assay Points (200-50,000)
  • 100 (17)
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  • 500 (40)
  • 5000 (21)
  • 50000 (9)
Assay Target Class
  • Antibody (36)
  • DNA (4)
  • Fc-receptor (12)
  • Peptide (1)
  • Phosphoprotein (7)
  • Protein (7)
Automation Compatible
  • Yes (91)
Depth
  • 33.0 in (2)
  • 49.0 cm (1)
Experimental Type
  • In vitro (78)
Format
  • Microplates (76)
Imaging Modality
  • High Content (1)
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  • 51-100 (1)
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  • LabChip GXII Touch 24 (1)
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  • Operetta (29)
  • Operetta CLS AND Opera Phenix (8)
Type
  • High pI (7.0 - 9.0) (1)
  • Low pI (3.0 - 7.0) (1)

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1-25 of 161 Products & Services

  • EnSight Multimode Plate Reader

    EnSight Multimode Plate Reader

    The EnSight multimode plate reader offers HTS Alpha, Ultra-sensitive Luminescence and fast well-imaging technologies alongside conventional multimode detection technologies. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
  • Spectrum-CU-Hero

    IVIS Spectrum In Vivo Imaging System

    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina III In Vivo Imaging System

    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • FMT In Vivo Imaging Instrument

    FMT 1000 In Vivo Imaging System

    The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
  • LabChip GX GXII Touch Product

    LabChip GXII Touch Protein Characterization System

    The LabChip® GXII Touch protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Leveraging microfluidic electrophoretic separation technology, the LabChip® GXII Touch system enables rapid characterization with minimal sample preparation setup and sample input volume.
  • JANUS G3 Btx Pro-Plus

    JANUS G3 BioTx Pro Plus Workstation

    The JANUS® G3 Bio Tx Pro Plus offers full walk-away automation for high-throughput process development, enabling more data from precious starting materials and limited resources.
  • IVIS-SpectrumCT-Hero

    IVIS® SpectrumCT In Vivo Imaging System

    The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS In Vivo Imaging System

    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • Operetta CLS High-Content Analysis System

    Operetta CLS High-Content Analysis System

    Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
  • SpectrumBL-CU-Hero

    IVIS® SpectrumBL High-Throughput In Vivo Optical Imaging System

    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • VictorX_ImageA_320px

    VICTOR Multilabel Plate Reader

    The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina LT In Vivo Imaging System

    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • EnVision 2105 multimode plate reader

    EnVision Multimode Plate Reader

    The EnVision® 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

    The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP).

  • JANUS G3 BioTx Pro Workstation

    JANUS G3 BioTX Pro Workstation

    The affordable and compact JANUS® G3 BioTx Pro Automated Workstation enables consistent, time-saving small-scale protein purification and sample preparation for analytical protein characterization required to support quality by design experimentation in both upstream and downstream processes.

    Ideal Workstation for:

    • Expression optimization
    • Cell line selection
    • Purification process development
    • Bioanalytical sample preparation
  • IgG4 (human) isotyping AlphaLISA Detection Kit

    The AlphaLISA Human IgG4 Detection Kit is designed for detection, quantitation, and isotyping of human IgG4 in cell culture medium and non-human serum, using a homogeneous (no wash steps, no separation steps) assay. The assay shows negligible cross-reactivity with other human IgG isotypes and monkey IgG.
  • LANCE Ultra Biomarker

    Kappa Light Chain (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human Kappa Light Chain Detection Kit is designed for detection and quantitation of human kappa light chain in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 1012.00 USD - 13500.00 USD
  • IgA (mouse) AlphaLISA Detection Kit

    The AlphaLISA immunoassay kit for detection and quantitation of mouse IgA in cell culture/non-mouse serum allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
    Price Range : 776.00 USD - 12100.00 USD
  • LANCE Ultra Biomarker

    Host Cell Residual DNA contamination LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Residual DNA Contamination Detection Kit is designed for detection and quantitation of DNA contaminants in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 877.00 USD - 11700.00 USD
  • AlphaLISA SureFire Ultra p-VEGF Receptor 2 (Tyr1175) Assay Kit

    The AlphaLISA® SureFire® Ultrap-VEGF Receptor 2 (Tyr1175) assay is a sandwich immunoassay for quantitative detection of phospho-VEGFR Receptor 2 (phosphorylated on Tyr1175) in cellular lysates using Alpha Technology.
    Price Range : 553.00 USD - 35300.00 USD
  • AlphaLISA SureFire Ultra p-4E-BP1 (Thr37/46) Assay Kit

    The AlphaLISA® SureFire® Ultra™ p-4E-BP1 (Thr37/46) assay is a sandwich immunoassay for quantitative detection of phospho-4EBP1 (phosphorylated on Thr37/46) in cellular lysates using Alpha Technology.
    Price Range : 553.00 USD - 35300.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-Mouse IgG3 (isotyping) AlphaLISA Acceptor beads

    AlphaLISA® Acceptor beads conjugated to a anti-mouse IgG3. This bead can be used to create no-wash AlphaLISA assays for isotyping and other applications.
    Price Range : 708.00 USD - 29000.00 USD
  • C-peptide (human) AlphaLISA Kit

    AlphaLISA® no-wash immunoassay kit for detection of human C-peptide (human connecting peptide) in serum, buffered solution or cell culture medium.
    Price Range : 1851.00 USD - 12300.00 USD
  • Alpha Donor Bead Antibody Conjugated

    Anti-Human IgG Alpha Donor beads

    Alpha Donor beads conjugated to mouse anti-human IgG (Fc-specific) antibody. This bead can be used to capture human IgG antibodies containing an Fc-region for Alpha no-wash protein detection, Fc-receptor binding, antibody detection, antibody binding, and other applications.
    Price Range : 611.00 USD - 11000.00 USD
  • AlphaLisa Analyte 2

    DNA (liquid), AlphaLISA

    DNA standard for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Host Cell Residual DNA kit, but can be ordered separately.
    List Price : 309.00 USD
  • IgG2 (bovine) AlphaLISA Detection Kit

    The AlphaLISA immunoassay kit for detection and quantitation of bovine IgG2 in serum, plasma, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
    Price Range : 841.00 USD - 13500.00 USD
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