PerkinElmer

Biomarker Detection

OF

Biomarker detection is key for advancing precision medicine. Use us as your comprehensive source for biomarker detection, from biomarker assay development to primary and secondary screening.

Our products for biomarker detection include:

  • AlphaLISA® immunoassay kits for high sensitivity and large signal to background in a variety of sample matrices, from human serum to cell culture media to CSF
  • LANCE® TR-FRET analyte detection technology
  • DELFIA (dissociation-enhanced lanthanide fluorescence immunoassay) TRF ELISA alternative technology
  • Multimode plate readers
  • Cellular, tissue, and in vivo imaging systems

We design our biomarker detection reagents and kits to excel in applications that rely on high sensitivity, wide dynamic range, and easy automation. With no wash or separation steps necessary, our homogeneous AlphaLISA immunoassays achieve faster run-times than any ELISA assay on the market.

Business Insights (3)
Filters:

1-3 of 3 Business Insights

Sort by

  • Application Note

    Multiplex 2D Imaging of NIR Molecular Imaging Agents on the IVIS SpectrumCT and FMT 4000

    Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing tumor progression or response to therapy. This approach for tumor assessment requires the use of near infrared (NIR) imaging agents specific for different aspects of tumor biology, and this Application Note highlights the ease and utility of multiplex NIR fluorescence imaging to characterize the complex biology within tumors growing in a living mouse.

  • Application Note

    Imaging Hepatocellular Liver Injury using NIR-labeled Annexin V

    Drug induced liver injury (DILI) is a major reason for late stage termination of drug discovery research projects, highlighting the importance of early integration of liver safety assessment in the drug development process. A technical approach for in vivo toxicology determination was developed using Acetaminophen (APAP), a commonly used over-the-counter analgesic and antipyretic drug, to induce acute hepatocellular liver injury.

  • Poster

    Combined efficacy & toxicity imaging following acute 5-FU treatment of HT-29 tumor xenografts

    Cancer chemotherapy can produce severe side effects such as suppression of immune function and damage to heart muscle, gastrointestinal tract, and liver. If serious enough, tissue injury can be a major reason for late stage termination of drug discovery research projects, so it is becoming more important to integrate safety/toxicology assessments earlier in the drug development process. There are a variety of traditional serum markers, tailored mechanistically to specific tissues, however there are no current non-invasive assessment tools that are capable of looking broadly at in situ biological changes in target and non-target tissue induced by chemical insult.

Products & Services (737)
Filters:

Filters :

Product Type
  • Accessories (3)
  • Instruments (4)
  • Reagents (727)
  • Services (1)
  • Software and Informatics (2)
Assay Target
  • 4-1BBL (1)
  • A1AT (2)
  • Adiponectin (3)
  • Aflatoxin (2)
  • Agglutinin (soybean) (2)
  • Albumin (5)
  • Alpha-synuclein (2)
  • and three open channels (1)
  • ANGPT1 (4)
  • ANGPT2 (2)
  • ANGPT3 (2)
  • ANGPTL3 (2)
  • ANGPTL4 (4)
  • ApoA1 (4)
  • ApoB (2)
  • ApoC3 (2)
  • ApoE (4)
  • AST (1)
  • Aβ1-40 (3)
  • Aβ1-42 (2)
  • Aβ1-x (1)
  • Aβ40 (3)
  • Aβ42 (1)
  • B7-H5 (2)
  • BACE-1 (2)
  • BCL-2 (2)
  • Bcl2 (2)
  • Beef troponin (2)
  • Beta-2 microglobulin (2)
  • BMP-7 (2)
  • BMP-9 (2)
  • BRCA2 (2)
  • BTK (1)
  • BTLA (2)
  • c-Myc (2)
  • C-peptide (4)
  • CA125 (1)
  • cardiac Troponin I (1)
  • Cardiac Troponin T (2)
  • CCL1 (1)
  • CCL18 (1)
  • CCL2 (4)
  • CCL3 (3)
  • CCL4 (3)
  • CCL5 (3)
  • CCL8 (1)
  • CD117 (2)
  • CD20 (3)
  • CD276 (2)
  • CD28 (2)
  • CD4 (4)
  • CD45RO (1)
  • CD68 (2)
  • CD8 (4)
  • CD80 (3)
  • CD86 (3)
  • Chloramphenicol (2)
  • CHO HCP (2)
  • CHO-P (2)
  • COL1A1 (3)
  • Collagen IV (2)
  • Corticosterone (2)
  • Cortisol (3)
  • COX-2 (2)
  • CRP (2)
  • Cry1Ab/1Ac (2)
  • Cry1F (2)
  • Cry2A (2)
  • CTLA4 (4)
  • CXCL1 (2)
  • CXCL1/GROα (2)
  • CXCL10 (5)
  • CXCL11 (1)
  • CXCL12 (2)
  • CXCL13 (4)
  • CXCL4/PF4 (2)
  • CXCL9 (3)
  • Cyr61 (1)
  • D-dimer (1)
  • E-Cadherin (4)
  • E.coli HCP (2)
  • EGF (4)
  • EGFR (4)
  • EPO (1)
  • ErbB2 (3)
  • Factor VIII (3)
  • FASL (1)
  • FCGR3A (6)
  • FGF23 (2)
  • Fibrinogen (4)
  • Fibronectin (4)
  • FLT-1 (2)
  • FOXP3 (2)
  • Frataxin (4)
  • FSH (4)
  • FSP1 (2)
  • G-CSF (1)
  • GAD67 (4)
  • Galectin 9 (2)
  • GAPDH (1)
  • GDNF (2)
  • Ghrelin (4)
  • GITR (1)
  • GLP-1 (3)
  • Glucagon (3)
  • GM-CSF (2)
  • Growth Hormone (1)
  • GSK3β (1)
  • HBeAg (1)
  • HBsAg (2)
  • hCG (4)
  • HCV cAg (1)
  • HLA-C (2)
  • HLA-E (2)
  • HO-1 (2)
  • HO-2 (2)
  • HVEM (2)
  • Hyaluronic Acid (2)
  • ICAM-1 (3)
  • IFN-λ2 (4)
  • IFNα (5)
  • IFNβ (2)
  • IFNγ (16)
  • IgA (5)
  • IgE (3)
  • IGF1 (7)
  • IGF2 (1)
  • IgG (12)
  • IgG1 (4)
  • IgG2 (2)
  • IgG2a (1)
  • IgG2b (1)
  • IgG3 (1)
  • IgG4 (2)
  • IgM (6)
  • IL-1RA (3)
  • IL-23 (2)
  • IL-23A (2)
  • IL-31 (2)
  • IL-6 (3)
  • IL10 (5)
  • IL11 (2)
  • IL12 (9)
  • IL13 (7)
  • IL15 (1)
  • IL17 (1)
  • IL17A (13)
  • IL17F (4)
  • IL18 (5)
  • IL18BP (2)
  • IL1α (4)
  • IL1β (10)
  • IL2 (8)
  • IL21 (2)
  • IL22 (3)
  • IL23 (2)
  • IL25 (4)
  • IL28B (4)
  • IL31 (2)
  • IL33 (4)
  • IL4 (9)
  • IL5 (4)
  • IL6 (10)
  • IL7 (1)
  • IL8 (6)
  • Influenza A NP (1)
  • Insulin (6)
  • IP10 (6)
  • Kappa light chain (4)
  • KIM-1 (1)
  • LAG3 (2)
  • Lambda light chain (4)
  • Laminin (2)
  • LC3B (3)
  • LDH (2)
  • Leptin (5)
  • MANF (4)
  • MBNL1 (3)
  • MCP2 (1)
  • MEK1 (1)
  • Mesothelin (2)
  • MIP1α (2)
  • MMP-12 (2)
  • MMP-7 (1)
  • MMP1 (1)
  • MMP12 (2)
  • MMP13 (2)
  • MMP2 (1)
  • MMP3 (2)
  • MMP7 (2)
  • MMP8 (4)
  • MMP9 (2)
  • mTOR (1)
  • Myeloperoxidase (1)
  • Myoglobin (1)
  • N-cadherin (2)
  • Neprilysin (1)
  • NGAL (2)
  • Nidogen-1 (4)
  • NNMT (1)
  • Oncostatin M (4)
  • Osteoprotegerin (3)
  • OX40L (1)
  • p24 (3)
  • p53 (4)
  • p62 (1)
  • PAI-1 (2)
  • panCK (2)
  • PCSK9 (2)
  • PD-1 (4)
  • PD-L1 (4)
  • PD-L2 (1)
  • PDGF (2)
  • PEG IgM (1)
  • PER.C6 HCP (3)
  • Periostin (1)
  • Perlecan (4)
  • PIGF (2)
  • PIP Collagen (4)
  • PON2 (1)
  • Progesterone (1)
  • Protein A (1)
  • PSA (1)
  • PSMA (2)
  • PTEN (4)
  • Residual DNA (4)
  • Residual Protein A (1)
  • S100A4 (2)
  • SCF (2)
  • SDF1 (2)
  • SHP2 (1)
  • SLP-76 (1)
  • Somatostatin (2)
  • STAT4 (1)
  • STAT5 (1)
  • STAT6 (1)
  • SYK (2)
  • Tau (3)
  • TDP-43 (4)
  • Testosterone (2)
  • TFF3 (1)
  • TGF-β1 (2)
  • TIM-3 (2)
  • TIMP1 (2)
  • TIMP2 (2)
  • TNFR1 (4)
  • TNFα (15)
  • tPA (2)
  • TRAIL (2)
  • TSH (4)
  • TSLP (4)
  • Utrophin (2)
  • VEGF-A (4)
  • VEGFR1 (2)
  • Vimentin (2)
  • VISTA (2)
  • α-tubulin (3)
  • β-NGF (1)
Target Species
  • Bovine (38)
  • CHO (2)
  • Cynomolgus (4)
  • Human (504)
  • Monkey (2)
  • Mouse (60)
  • Ovine (2)
  • Plant (6)
  • Porcine (16)
  • Rabbit (2)
  • Rat (5)
Application
  • Enzymatic (3)
  • High biotin samples (8)
  • Kinase (8)
  • Multiplexing (9)
  • Protein Analysis & Detection (670)
  • Protein-protein interactions (14)
Therapeutic Area
  • Agriculture/Plant (6)
  • Angiogenesis (28)
  • Arthritis (9)
  • Atherosclerosis (7)
  • Autophagy (4)
  • Bacterial infection (4)
  • Biologics/Bioprocess (69)
  • Cancer (162)
  • Cardiovascular (15)
  • Central Nervous System (32)
  • CNS & Neurologic (1)
  • Food Testing (6)
  • Inflammation (216)
  • Kidney (2)
  • Metabolic (75)
  • Oncology/Cancer (13)
  • Virology (5)
Product Brand Name
  • Alpha (1)
  • AlphaLISA (449)
  • AlphaLISA SureFire Ultra (11)
  • AlphaPlex (20)
  • AlphaScreen (1)
  • AlphaScreen SureFire (1)
  • BacteriSense (1)
  • DELFIA (9)
  • EnSight (1)
  • EnSpire (2)
  • EnVision (2)
  • FolateRSense (1)
  • HypoxiSense (1)
  • IntegriSense (3)
  • LANCE (11)
  • LANCE SureLight (3)
  • LANCE Ultra (174)
  • OnPoint (1)
  • Opal (6)
  • OsteoSense (3)
  • TLectinSense (1)
  • Victor (1)
  • ViewLux (1)
  • XenoLight (8)
Detection Method
  • Absorbance (4)
  • Alpha (497)
  • DELFIA TRF (8)
  • Fluorescence (10)
  • Fluorescence Polarization (3)
  • Image-based Cytometry (1)
  • Luminescence (4)
  • MSI (6)
  • Time-Resolved Fluorescence (TRF) (183)
  • TR-FRET (171)
Antibody Conjugates
  • Anti-human IgG (2)
  • Anti-mouse IgG (3)
  • Anti-rabbit IgG (3)
  • Biotin (1)
  • Protein A (1)
  • Protein G (1)
  • Streptavidin (7)
Radioisotope
  • C-14 (1)
Fluorescent Agent Type
  • Targeted (17)
Fluorophore
  • Eu-N1 (4)
  • Eu-N1-ITC (2)
  • Eu-W1024 (6)
  • Eu-W1024-ITC (1)
  • Eu-W1284-Iodoacetamido (1)
  • Eu-W8044 (1)
  • Eu-W8044-DTA (1)
  • Opal 520 (5)
  • Opal 540 (3)
  • Opal 570 (4)
  • Opal 570 and Opal 690 (1)
  • Opal 620 (3)
  • Opal 650 (3)
  • Opal 670 (1)
  • Opal 690 (3)
  • Sm-N1 (1)
  • SureLight APC (3)
  • Tb-N1 (1)
  • ULight (2)
Assay points(200-50,000)
  • 100 (206)
  • 1000 (1)
  • 10000 (108)
  • 500 (399)
  • 5000 (294)
  • 50000 (6)
Assay Target Class
  • Aminoglycan (2)
  • Antibody (46)
  • Collagen (3)
  • Cytokine (214)
  • DNA (4)
  • Fc-receptor (6)
  • Hormone (44)
  • Peptide (22)
  • Phosphoprotein (4)
  • Protein (316)
  • Receptor (2)
  • Small Molecule (2)
Automation Compatible
  • No (5)
  • Yes (695)
Experimental Type
  • In vitro (550)
Format
  • Microplates (573)
Imaging Modality
  • Chemilumiluminescence (2)
  • Fluorescence (17)
Maximum Temperature (Celsius)
  • 40-50 (2)
  • 50-60 (2)

1-12 of 737 Products & Services

Sort by

  • EnVision 2105 multimode plate reader

    EnVision 2105 Multimode Plate Reader

    The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

    The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

  • ViewLux uHTS Microplate Imager

    ViewLux uHTS Microplate Imager

    The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

    The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

  • EnSight Multimode Plate Reader

    EnSight Multimode Plate Reader

    The EnSight multimode plate reader combines labeled & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
  • VictorX_ImageA_320px

    VICTOR Multilabel Plate Reader

    The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
  • AlphaLISA immunoassay kits

    CXCL12/SDF-1 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human CXCL12 (SDF-1) enables the quantitative determination of human CXCL12 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 451.00 USD - 9900.00 USD
  • NGAL (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for NGAL is designed for the quantitative determination of Neutrophil Gelatinase Associated Lipocalin (NGAL) also known as lipocalin 2 in cell culture media and human serum using a homogeneous AlphaLISA assay (no wash steps). The assay shows no cross-reactivity with mouse NGAL, rat NGAL, bovine NGAL and chicken NGAL.
    Price Range : 588.00 USD - 11400.00 USD
  • S100A4/FSP1 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human S100A4 enables the quantitative determination of human S100 calcium-binding protein A4 in serum, plasma, cerebrospinal fluid (CSF), buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 451.00 USD - 9900.00 USD
  • AlphaLISA immunoassay kits

    PER.C6® HCP AlphaLISA Detection Kit

    The AlphaLISA® PER.C6® HCP Detection Kit is designed for the quantitative detection of PER.C6® contaminants in buffer and cell culture media using a homogeneous (no wash steps, no separation steps) assay.
    Price Range : 1539.00 USD - 10200.00 USD
  • CXCL4/PF4 (Human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for CXCL4/PF4 enables the quantitative determination of CXCL4/PF4 in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows minumum cross-reactivity with mouse CXCL4/PF4 and human CXCL4L1/PF4V.
    Price Range : 644.00 USD - 19300.00 USD
  • Factor VIII (human) AlphaLISA Biotin-Free Detection Kit

    The AlphaLaISA® Human Factor VIII Biotin-Free Detection Kit is designed for the quantitative detection of human Factor VIII in buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.
    Price Range : 478.00 USD - 10500.00 USD
  • AlphaLISA assay principle

    TSH (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human TSH enables the quantitative determination of human thyroid stimulating hormone (TSH) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 644.00 USD - 19300.00 USD
  • AlphaLISA immunoassay kits

    Cry1Ab/1Ac AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for Cry1Ab/1Ac enables the detection and quantitation of Cry1Ab or Cry1Ac in plant seed and leaf extracts using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 607.00 USD - 9400.00 USD
  • Jump to: