PerkinElmer

AlphaLISA Binding Kits

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The interactions and binding of proteins are implicated in a large number of biological processes. The need for an efficient, highly sensitive assay to study large protein interactions is increasingly important. Alpha Technology is a highly flexible, homogeneous, no-wash assay ideal for the measurement of protein interactions and complexes as large as 200 nm in size. A bead-based proximity assay, Alpha Technology offers the possibility to assay many biological targets, including enzymes, receptor-ligand interactions, low affinity interactions, second messenger levels, DNA, RNA, proteins, peptides, sugars and small molecules.

Features:

  • No-wash steps, no separation steps
  • Ease-of-use: few addition steps, fast assay development
  • Broad range of affinities: detect strong or weak interactions, from pM to mM affinity
  • Distance: measure very large protein or antibody complexes – spanning up to 200 nm or more
  • High avidity: multiple binding sites on each bead enables use of nanomolar concentrations of antibodies or proteins, as well as use of low affinity binders

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Narrow your results
Assay Target
  • CD80 (1)
  • CD86 (1)
  • CTLA4 (2)
  • EGF (1)
  • EGFR (1)
  • FCGR1 (1)
  • FCGR2A (2)
  • FCGR2B (1)
  • FCGR3A (2)
  • HLA-DRA (1)
  • LAG3 (1)
  • PD-1 (2)
  • PD-L1 (2)
  • PDGF-BB (2)
  • PDGFR (2)
Target Species
  • Human (9)
  • Mouse (1)
Application
  • Protein Analysis & Detection (8)
  • Protein-protein interactions (15)
Therapeutic Area
  • Biologics/Bioprocess (6)
  • Cancer (8)
Assay points(200-50,000)
  • 100 (4)
  • 500 (16)
  • 5000 (16)
Assay Target Class
  • Fc-receptor (6)
  • Protein (8)
Experimental Type
  • In vitro (4)
Format
  • Microplates (4)

"AlphaLISA Binding Kits" 1-16 of 16 Products and Services

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AlphaLISA immunoassay kits

FCGR3A/CD16A (176Phe/F158) (human) AlphaLISA Detection Kit

This kit is designed for the detection of binding activity between human FCGR3A (176Phe) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
Price Range : 583.00 USD - 10600.00 USD
Assay principle for LANCE TR-FRET binding assay

CTLA4-CD86 AlphaLISA Binding Kit

This kit is designed for the detection of binding activity between Human CTLA-4 and CD86, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding to CTLA-4/CD86.
Price Range : 1800.00 USD - 11000.00 USD
AlphaLISA binding assay

PDGF-BB/PDGFRα (human) AlphaLISA Binding Kit

This kit is designed for the detection of binding activity between Human PDGF-BB and PDGFRα, using a homogeneous AlphaLISA assay (no wash step). This assay can facilitate the design and development of antibody therapeutics by using competitive binding to PDGF-BB and PDGFRα.
Price Range : 1747.00 USD - 14000.00 USD
AlphaLISA immunoassay kits

FcγR2A/CD32a (167R) AlphaLISA Binding Kit

This kit is designed for the detection of binding between FCGR2A (CD32a) (167R) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
Price Range : 2123.00 USD - 10600.00 USD
AlphaLISA immunoassay kits

FcRn (human) AlphaLISA Binding Kit

The AlphaLISA human FcRn binding kit is designed for the detection of binding between FcRn and human IgG using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics using a competition assay format.
Price Range : 2122.00 USD - 10600.00 USD
AlphaLISA binding assay

HLA-DRA/LAG3 (human) AlphaLISA Binding Kit

This kit is designed for the detection of binding activity between Human HLA-DRA and LAG3, using a homogeneous AlphaLISA assay (no wash step). This assay can facilitate the design and development of antibody therapeutics by using competitive binding to HLA-DRA and LAG3.
Price Range : 1747.00 USD - 14000.00 USD
Assay principle for LANCE TR-FRET binding assay

CTLA4-CD80 AlphaLISA Binding Kit

This kit is designed for the detection of binding activity between Human CTLA-4 and CD80, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding to CTLA-4/CD80.
Price Range : 1800.00 USD - 11000.00 USD
AlphaLISA binding assay

PDGF-BB/PDGFRβ (human) AlphaLISA Binding Kit

This kit is designed for the detection of binding activity between Human PDGF-BB and PDGFRβ, using a homogeneous AlphaLISA assay (no wash step). This assay can facilitate the design and development of antibody therapeutics by using competitive binding to PDGF-BB and PDGFRβ.
Price Range : 1747.00 USD - 14000.00 USD
AlphaLISA Binding Assay kits

PD-1/PD-L1 (human) AlphaLISA Binding Kit

The AlphaLISA® PD-1/PD-L1 Binding Kit is designed for the detection of binding activity between Human PD-1 and PD-L1, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of therapeutics which competitively inhibit PD-1/PD-L1 interaction.
Price Range : 695.00 USD - 9700.00 USD
Alpha binding assay principle

EGF/EGFR AlphaLISA Binding Kit

The AlphaLISA® EGF/EGFR Binding Kit is designed for the detection of binding activity between Human EGF and EGFR, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of therapeutics which competitively inhibit the EGF/EGFR interaction.
Price Range : 695.00 USD - 9700.00 USD
Alpha Fc receptor bind

FCGR3A/CD16a (176Val/V158) AlphaLISA Binding Kit

This kit is designed for the detection of binding activity between human FCGR3A (176Val) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
Price Range : 695.00 USD - 10600.00 USD

FCGR2B/CD32b AlphaLISA Binding Kit

This kit is designed for the detection of binding between FCGR2B (CD32b) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
Price Range : 2123.00 USD - 10600.00 USD

FcγR2A/CD32a (167H) AlphaLISA Binding Kit

This kit is designed for the detection of binding between FCGR2A (CD32a) (167H) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
Price Range : 2123.00 USD - 10600.00 USD
Assay principle for AlphaLISA mouse PD-1/PD-L1 binding assay

PD-1/PD-L1 (mouse) AlphaLISA Binding Kit

The AlphaLISA® mouse PD-1/PD-L1 binding assay enables development and characterization of small and large molecule anti-mouse PD-1 or PD-L1 reagents for in vitro and in vivo studies, testing of other putative binding ligands such as PD-L2 or characterization of ligand subregions for their ability to block binding, and determination of mouse cross-reactivity of anti-human PD-1 or PD-L1 reagents using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 2123.00 USD - 10600.00 USD
AlphaLISA immunoassay kits

FcγR3B (CD16b) AlphaLISA Binding Kit

The AlphaLISA FCGR3B (CD16b) binding kit is designed for the detection of binding between FcγR3B (CD16b) and human IgG Fc fragment using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics using a competition assay format.
Price Range : 2122.00 USD - 10600.00 USD
AlphaLISA immunoassay kits

FCGR1/CD64 AlphaLISA Binding Kit

This kit is designed for the detection of binding between FCGR1 (CD64) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
Price Range : 2123.00 USD - 10600.00 USD

"AlphaLISA Binding Kits" 1-16 of 16 Products and Services