PerkinElmer

Radiochemicals

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Radiometric detection is considered the gold standard for many applications, from drug discovery and development to plant sciences. The technique achieves sub-femtogram sensitivity levels, and quantitates the binding and activity of radiolabeled compounds with high specificity and sensitivity. As the leading supplier of research radiochemicals, we offer a broad portfolio of products for any radiochemistry need.

Our radiochemical analysis products include:

  • Radionuclides such as 124I, 14C, 89Zr, 90Y, 125I, 131I, 22Na, 32P, 33P, 35S, 3H, 45Ca, 51Cr, 54Mn, 55Fe, 59Fe, 85Sr, 86Rb
  • EasyTag protein labeling mixes
  • EasyTide radiolabeled nucleotides
  • NEN radiolabeled compounds
  • SPA Enzymatic assays and imaging beads

Our radiolabeled compounds are useful in a wide range of applications:

  • Research in cancer, CNS and neurologic disease, cardiovascular and metabolic disease, inflammation, and other disorders
  • Kinetic and mechanistic studies
  • Scintillation assays
  • Radiometric cAMP assays
  • Detection of binding to over 80 different receptor types

Our radiometric reagents are not reliant on the use of antibodies for detection and read-out – just one of the reasons they are so widely used.

For research and investigational use only.

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"Radiochemicals" 1-50 of 778 Products and Services

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L-[35S]-Methionine, High radioactive concentration, 50mM Tricine, 10mM BME

Methionine amino acid labeled with 35S. This formulation is provided at high radioactive concentration, and contains β-mercaptoethanol.

L-[1-14C]-Ornithine,>97%

50 µCi quantities of L-[1-14C]-Ornithine are available for your research.

Hypoxanthine Monohydrochloride, [3H(G)]-,>97%, 5mCi (185MBq)

5 mCi quantities of [3H(G)]-Hypoxanthine Monohydrochloride are available for your research. 

Norepinephrine, Levo-[ring-2,5,6-3H]

Levo-Norepinephrine, tritiated on the ring group. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET).

dCTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 33P.
PerkinElmer

Polylysine YSI 1G

Poly-lysine-coated SPA beads, for use in proximity-based radiometric scintillation assays.

PDGF [125I] (human)

NEX433 [125I]-PDGF BB homodimer has been shown to work in RIA and receptor studies, using CHO cell line transfected with human PDGF B receptor, and human artery smooth muscle cells.

Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid (AMPA), DL-α-[5-Methyl-3H]

DL-α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid (AMPA), tritiated at the 5-methyl position. AMPA acts as an agonist at the AMPA receptor.
Yittrium-90

Yttrium-90

Yttrium-90 Radionuclide. 3 day precalibration. Yttrium chloride in 0.05M HCl Shipped ambient. ~500Ci(18.5TBq)/mg

WARFARIN, [14C]

50 µCi quantities of [14C]-WARFARIN are available for your research.

Vasopressin (8-L-Arginine), [Phenylalanyl-3,4,5-3H(N)]

Vasopressin, tritiated on the phenylalanine residue. Vasopressin binds and activates vasopressin receptors.

Paroxetine, [Phenyl-6'-3H]

Paroxetine (Paxil), tritiated at the phenyl-6' position. Paroxetine is a selective serotonin reuptake inhibitor (SSRI). This product has a scheduled lot release for the first Monday in May and November.

Lysergic Acid Diethylamide, [N-Methyl-3H]-, 250µCi (9.25MBq)

Lysergic Acid Diethylamide (LSD), tritiated on the N-methyl group. LSD is a partial agonist of dopamine D2 receptors. It also binds most serotonin receptors (5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT5B and 5-HT6). This product has a scheduled lot release for the second Monday in April, August and December.
Zirconium-89 injected into mouse, imaged using G8 PET/CT

Zirconium-89

Visualize and quantify uptake of monoclonal antibodies (mAbs) using Zirconium-89 (89Zr). With a long-lived half-life of (3.3 days), 89Zr is well suited as a PET Imaging biomarker to access target expression as well as tumor targeting of mAbs.

WAY100635, [METHOXY-3H], 250 uCi

WAY-100635, tritiated on the methoxy group. WAY-100635 acts as an antagonist at serotonin 5-HT1A receptors. It also acts as an agonist at dopamine D4 receptors.

Dihydroxyphenylethylamine, 3,4-[7-3H]

Dihydroxyphenylethylamine (dopamine, DA), tritiated at the 7 position. Dihydroxyphenylethylamine is a neurotransmitter and is the primary endogenous ligand for dopamine receptors. This product has a scheduled lot release for the second Monday in April and October.

8-Hydroxy-DPAT, [Propyl-2,3-ring-1,2,3-3H]-

8-OH-DPAT radioligand tritiated at the 1,2,3 position on the propyl-2,3-ring. 8-OH-DPAT is a serotonin receptor agonist specific for the 5-HT1A and 5-HT7 receptors.

Glutamic Acid, L-[14C(U)]

50 µCi quantities of L-[14C(U)]-Glutamate are available for your research.

dCTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 32P.
PerkinElmer

Streptavidin PVT 150MG

Streptavidin-coated SPA beads, for capturing biotinylated biomolecules in proximity-based radiometric scintillation assays.

Oleoyl Coenzyme A, [Oleoyl-1-14C]-, 10µCi (370kBq)

10 µCi quantities of [Oleoyl-1-14C]-Oleoyl Coenzyme A are available for your research. This product has a scheduled release date for the third Monday in July.

MIP-1α (human, recombinant), [125I]

Human recombinant macrophage inflammatory protein 1-alpha (MIP-1α; CCL3), labeled with 125I. MIP-1α is a cytokine involved in acute inflammation, and binds C-C chemokine receptors CCR1, CCR4, and CCR5.

Pyruvic Acid, Sodium Salt, [1-14C], 50µCi (1.85MBq)

50 µCi quantities of [1-14C]-Pyruvic Acid, Sodium Salt are available for your research.

GTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Guanosine triphosphate, labeled on the alpha phosphate group with 33P.

dATPαS, [35S]- 500Ci/mmol, 10mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 35S.

Iodoantipyrine, 4-[N-Methyl-14C]

4-Iodoantipyrine, labeled with C-14 on the N-methyl group. Iodoantipyrine has been used to measure cerebral blood flow.

Hemicholinium-3 Diacetate Salt, [Methyl-3H]-, 250µCi (9.25MBq)

Hemicholinium-3 (HC3; hemicholine) Diacetate Salt, tritiated on the methyl group. Hemicholinium-3 blocks reuptake of choline by the high-affinity choline transporter. This product has a scheduled lot release for the second Monday in February and August.

Thyroxine, ([125I]-T4), Specific Activity: 1080-1320 µCi/µg

Thyroxine (T4) labeled with 125I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T4 detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

SCH 23390, [N-Methyl-3H]

SCH-23390 (halobenzazepine), tritiated on the N-methyl group. SCH-23390 acts as an antagonist at the dopamine D1 receptor.

dGTP, [α-32P]- 6000Ci/mmol 20mCi/ml EasyTide, 500 µCi

Deoxyguanosine triphosphate, labeled on the alpha phosphate group with 32P.

ATP, [γ-32P]- 6000Ci/mmol 10mCi/ml

Adenosine triphosphate, labeled on the gamma phosphate group with 32P

dATPαS, [35S]- 1250Ci/mmol, 12.5mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 35S.
PerkinElmer

Streptavidin PS 2G Imaging Beads

Streptavidin-coated SPA beads, for capturing biotinylated molecules in proximity-based scintillation assays.

Dehydroepiandrosterone, [1,2,6,7-3H(N)]-, 1mCi (37MBq)

1 mCi quantities of Dehydroepiandrosterone (DHEA) are available for your research.

Hydroxytryptamine Binoxalate (Serotonin Binoxalate), 5-[1-14C]

5-Hydroxytryptamine Binoxalate (Serotonin Binoxalate), labeled with C-14 at the 1-position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors. NEC855 replaces product NEC225, which was labeled at the 2-position.

NAD, [32P]- 800Ci/mmol 5mCi/ml Lead

Nicotinamide Adenine Dinucleotide (NAD) 32P is labeled on the adenylate phosphate

Peptide YY (Human), ([125I]-PYY)

Peptide YY, labeled with 125I. Peptide YY acts as a neuropeptide Y receptor Y2 agonist, is released in response to feeding, and is associated with appetite saiety.

Chromium-51 Radionuclide, Sodium Chromate in Normal Saline (pH 8-10), Steri-packaged

Chromium-51 (51Cr) radionuclide, commonly used as a label for target cells in chromium release assays, cell-mediated cytotoxicity studies, antibody-dependent cytotoxicity (ADCC) studies, and CAR-T cell development. Target cells uptake 51Cr radionuclide, and release the nuclide into the culture media upon cytolysis or cell death.

ATP, [γ-32P]- 6000Ci/mmol 10mCi/ml EasyTide Lead

Adenosine triphosphate, labeled on the gamma phosphate group with 32P.

(+)-Pentazocine, [Ring-1,3-3H]

(+)-Pentazocine radioligand tritiated at the 1,3 position on the ring. Pentazocine is a synthetic opioid shown to bind sigma 1 receptor.

Triolein, [Carboxyl-14C]-, 250µCi (1.85MBq)

250 µCi quantities of [Carboxyl-14C]-Triolein are available for your research.

ATP, [γ-33P]- 3000Ci/mmol, 10mCi/ml

Adenosine triphosphate, labeled on the gamma phosphate group with 33P.
PerkinElmer

WGA PS 2G Imaging Bead

WGA-coated SPA beads, for capturing cell membranes in proximity-based scintillation assays.
PerkinElmer

Streptavidin PVT 2G

Streptavidin-coated SPA beads, for capturing biotinylated biomolecules in proximity-based radiometric scintillation assays.

Uridine Diphosphate Glucuronic Acid, [Glucuronyl-14C(U)]-, 10µCi (370kBq)

10 µCi quantities of [Glucuronyl-14C(U)]-Uridine Diphosphate Glucuronic Acid are available for your research.

Acetic Acid, sodium salt -[1-14C]

Acetic Acid labeled with 14C can be used to trace cell metabolism.
PerkinElmer

PDE YSI 2G

SPA (scintillation proximity assay) beads designed for the capture of [3H]AMP or [3H]GMP on specially prepared yttrium silicate beads.

Estradiol, [2,4,6,7,16,17-3H(N)]-, 1mCi (37MBq)

1 mCi quantities of tritiated estradiol are available for your research.

"Radiochemicals" 1-50 of 778 Products and Services

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