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Liver toxicity remains one of the main reasons for drug failure in clinical trials. Improving preclinical toxicity testing is a major prerequisite for improving the drug de-risking process. Early compound de-risking decisions require in vitro data with the highest possible biological relevance. Three dimensional (3D) microtissues, or spheroids, are one of the most well characterized models for 3D culture and cell-based drug screening due to their reproducibility and similarity to the in vivo situation.
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The affordable and compact JANUS® G3 BioTx Pro Automated Workstation enables consistent, time-saving small-scale protein purification and sample preparation for analytical protein characterization required to support quality by design experimentation in both upstream and downstream processes.
Ideal Workstation for: