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Zirconium-89-Friday Calibration

Visualize and quantify uptake of monoclonal antibodies (mAbs) using Zirconium-89 (89Zr). With a long-lived half-life of (3.3 days), 89Zr is well suited as a PET Imaging biomarker to access target expression as well as tumor targeting of mAbs.

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Part Number SKU Display Name
NEZ308000MC Zirconium-89-Monday Calibration
NEZ308A000MC Zirconium-89-Tuesday Calibration
NEZ308B000MC Zirconium-89-Wednesday Calibration
NEZ308C000MC Zirconium-89-Thursday Calibration
NEZ308D000MC Zirconium-89-Friday Calibration
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Overview

Zirconium-89 radionuclide, dispensed for Friday* calibration. This calibration date is currently only available in North America. 89Zr is particularly suitable for PET imaging of internalizing mAbs. 89Zr-immuno-PET can offer excellent sensitivity and accurate quantification of mAbs or mAb-fragments in pre-clinical in vivo models. 89Zr's physical half-life of 78.4 hr matches the biological half-life of a mAb, as well as the time it needs to perfectly reach optimal target-to-non-target ratios. Literature suggests that PET image quality is not disturbed by the decay of this residualizing isotope.

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*Tuesday-Friday Calibration Dates and Delivery Schedule available in North America only

CAUTION: Contains a new drug for investigational use only in laboratory research animals, or for tests in vitro. Not for use in humans.

Specifications

Detection Method Radiometric
Product Brand Name NEN Radiochemicals
Quantity in a Package Amount 1.0 per pack
Radioisotope Zr-89
Radionuclide 89Zr
Shipping Condition Ambient
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Unit Size mCi

Resources, Events & More

Resource Type File Name File Format
Poster Multimodality workflow for assessing drug distribution & efficacy in breast cancer xenografts PDF  908 KB
Calendar 2017 Fresh Lot Calendar PDF  194 KB