The Vectra® 3 automated quantitative pathology imaging system accurately detects and measures weakly expressing and overlapping biomarkers within a single H&E, IHC or IF intact FFPE tissue section or TMA.
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The Vectra® 3 automated quantitative pathology imaging system is available as a 6-slide or 200-slide configuration. Both accurately detect and measure weakly expressing and overlapping biomarkers within a single H&E, IHC or IF intact FFPE tissue section or TMA. Vectra and inForm® software analysis combine the power of multiplexed biomarker imaging and quantitative analysis within a familiar digital pathology workflow to accelerate your cancer immunology research.
Tissue sections or TMAs can be labeled with immunofluorescent (IF) or immunohistochemical (IHC) stains, or with conventional stains such as H&E and trichrome. When using IF or IHC stains, multiple proteins can be measured on a per tissue, per cell, or per cell compartment (e.g. nuclear, cytoplasmic) basis - even when signals are spectrally similar, are located in the same cellular compartment or are obscured by autofluorescence.
Vectra 3 introduces the Phenochart™ whole slide contextural viewer with annotation capability into the digital workflow, where pathologists and technicians can navigate around slides and identify areas of interest for high-resolution multispectral acquisition. The system features automated slide handling, multispectral imaging technology, and unique pattern-recognition-based image analysis enabling quantitative data acquisition for up to 200 slides within a single batch run. It accurately measures protein and biomarker expression and morphometric characteristics in intact tissue sections for translational studies.
Disclaimer: For research use only. Not for use in diagnostic procedures.
|Export Control Classification Number||EAR99|
|Resource Type||File Name||File Format|
|Brochure||Phenoptics™ Research Solutions||PDF 11 MB|
|Poster||Understanding immune phenotypes and their spatial relationships to breast adenocarcinoma||PDF 1 MB|
|Product Info||Let's Rid the World of Ribbons - Infographic||PDF 822 KB|
|Product Note||Vectra 3: Quickening the Pace of Understanding||PDF 1 MB|
|Product Note||Quantitative Pathology Imaging and Analysis||PDF 2 MB|
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|Scientific Paper||NEJM: PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma||Link|
|Scientific Paper||Novartis Genoptix Shows Multiplexed IHC Test Better Predicts Immunotherapy Response||Link|
|Scientific Paper||Mlecnik, Bernhard, et al. "The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis." Science translational medicine 8.327 (2016)||Link|
|Scientific Paper||Nghiem, Paul T., et al. "PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma." New England Journal of Medicine (2016)||Link|
|Software Downloads||Click here to download latest software||Link|
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|Webinar||Untangling the tumor microenvironment: Illuminating the complex interactions and functions of immune cells||Link|