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ValiScreen Serotonin 5HT-2B (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

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Product Number
ES-314-C

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Overview

Stable recombinant cell line expressing the Serotonin, 5HT2B receptor. Human recombinant, in CHO-K1 host cell. We provide: Two vials of the recombinant cell line as frozen cells; Detailed product information including sequence, cell line properties, culture conditions, pharmacological properties of the recombinant receptor in binding and functional assays (cAMP). In addition, for total reassurance, we will provide up to two free replacements within in a 2 year period should you accidently lose your cell line.

In our ""standard"" cell lines where clonal selection is carried out with receptor binding: high and low expressors are then tested and selected for optimal binding and functional response according to the receptor specific transduction pathway.

Restriction for product sale could exist in some countries.

Disclaimer: This product contains living cells. Some cells may be restricted for sale in specified countries. Please inquire at your local sales office for more information.

Specifications

Assay Target Class GPCR
Assay Target Type Cell line
Assay Validated Binding, Calcium Fluorescence
G-Alpha Natural Receptor Gq/G11
Host Cell CHO-K1
Product Brand Name ValiScreen
Receptor Type 5-Hydroxytryptamine (Serotonin)
Second Messenger Release Calcium flux
Shipping Condition Dry Ice
Therapeutic Area Central Nervous System, Cardiovascular
Unit Size 5 million cells