Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
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ProSense® 750 EX is a protease activatable fluorescent in vivo imaging agent that is activated by key disease associated proteases such as Cathepsin B, L, S and Plasmin. ProSense750 EX is optically silent in its unactivated state and becomes highly fluorescent following protease-mediated activation.
ProSense750 EX can be used as a marker for disease progression and therapeutic response in animal models of arthritis. This agent can also be used as a marker for disease progression in animal tumor models.
Disclaimer: For laboratory use only. This product is intended for animal research only and not for use in humans.
|Fluorescent Agent Type||Activatable|
|One Unit Contains||10 mouse dose|
|Optical Imaging Classification||Fluorescence Imaging|
|Product Brand Name||ProSense|
|Shipping Condition||Blue Ice|
|Therapeutic Area||Atherosclerosis, Oncology/Cancer, Arthritis, Inflammation|
|Unit Size||1 Vial (10 doses)|
|Wave Length||750 nm|
|Resource Type||File Name||File Format|
|Brochure||FMT Fluorescence Tomography in vivo Imaging Systems||PDF 1 MB|
|Brochure||In Vivo Imaging Agents Brochure||PDF 2 MB|
|Application Note||In Vivo Imaging of Atherosclerosis Disease Using FMT||PDF 1 MB|
|Application Note||Multiplex 2D Imaging of NIR Molecular Imaging Agents on the IVIS SpectrumCT and FMT 4000||PDF 4 MB|
|Application Note||Noninvasive In Vivo Quantitation of Asthma Severity Using FMT||PDF 488 KB|
|Technical Note||ProSense 750 EX (Protocol)||PDF 258 KB|
|Technical Note||ProSense® 750 EX (Data Sheet)||PDF 315 KB|
|Citations Library||View peer reviewed publications using PerkinElmer's In Vivo Imaging Reagents||Link|