Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
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IntegriSense™ 750 is a targeted fluorescent imaging agent comprising a potent, selective non-peptide small molecule integrin avb3 antagonist and a near- infrared (NIR) fluorochrome. IntegriSense 750 has a shorter half life in tissue than IntegriSense 680. IntegriSense 750 washes out of tissues in ~ 96 hours to permit more frequent reinjection of the agent in longitudinal studies. This agent has been developed to enable in vivo visualization and quantification of integrin avb3 in tumor cells as well as in neovasculature, to monitor tumor growth, tumor angiogenesis, and treatment efficacy. Absorbance and fluorescence emission spectra of IntegriSense 750 in 1x PBS.
Disclaimer: For laboratory use only. This product is intended for animal research only and not for use in humans.
|Fluorescent Agent Type||Targeted|
|Optical Imaging Classification||Fluorescence Imaging|
|Product Brand Name||IntegriSense|
|Shipping Condition||Blue Ice|
|Therapeutic Area||Atherosclerosis, Oncology/Cancer, Angiogenesis|
|Unit Size||1 Vial (10 doses)|
|Wave Length||750 nm|
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|Resource Type||File Name||File Format|
|Brochure||In Vivo Imaging Agents Brochure||PDF 2 MB|
|Application Note||In Vivo Imaging of Atherosclerosis Disease Using FMT||PDF 1 MB|
|Application Note||Multiplex 2D Imaging of NIR Molecular Imaging Agents on the IVIS SpectrumCT and FMT 4000||PDF 4 MB|
|Technical Note||IntegriSense 750 (Protocol)||PDF 258 KB|
|Technical Note||IntegriSense™ 750 (Data Sheet)||PDF 57 KB|
|Citations Library||View peer reviewed publications using PerkinElmer's In Vivo Imaging Reagents||Link|