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inForm Cell Analysis

inForm® Cell Analysis enables quantitative per cell analysis of immunohistochemistry (IHC), immunofluorescence (IF), and RNA in-situ hybridization, enabling the separation of weak and spectrally overlapping markers, in single and multiplex assays.

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Part Number
CLS135781
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Overview

Cell Analysis can phenotype cells based on their biomarker expression within cells, nuclei and membranes. It is designed for individual research groups or small tissue pathology studies.

Key Features: 

  • Enables tissues to be studied at the cellular level using the Cell/Object Segmentation functionality
  • Enhanced tools for more accurate cell segmentation
  • Visualizes, analyzes, quantifies and phenotypes immune and other cells in-situ in solid tissue
  • Pathology Views to render immunofluorescence images as H&E, DAB and hematoxylin
  • Automated quantitation of biomarker expression from specific tissue types (e.g. tumor/stroma)
  • Separates weakly expressing and overlapping markers
  • Batch processing of images using customizable image analysis workflows
  • Scoring (% positivity, 0/1+/2+/3+, co-localization and more)
  • Export data and images for further analysis, for example: TIBCO Spotfire® Analyst for Quantitative Pathology
  • Supports PerkinElmer’s Phenoptics workflow solution for cancer immunology research

Resources, Events & More

All (23)
Resource Type File Name File Format
Brochure Brochure: Phenoptics Portfolio PDF  2 MB
Product Note Product Note: inForm Image Analysis Software PDF  2 MB
Application Note Application Note: Detecting Phenotypical Subgroups in Breast Cancer using Multiplexed Protein Expression Analysis in Intact Tissue Sections PDF  2 MB
Application Note Application Note: Evaluating EMT in FFPE Tissue Sections Using the inForm Data Analysis Software PDF  1 MB
Product Info Product Info: Let's Rid the World of Ribbons - Infographic PDF  822 KB
E-book Download Phenoptics Research Solutions E-book Link
Guide Guide: Opal Assay Development Link
Link Link: Multiparametric immune profiling in HPV– oral squamous cell cancer Link
Opal Multiplex IHC Assay Development Guide Guide: Opal Multiplex IHC Assay Development Guide
Resource Click Here to Download the Latest Software Software Downloads
Scientific Paper Publication: NEJM: Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma Link
Scientific Paper Publication: Esbona, Karla, et al. "COX-2 modulates mammary tumor progression in response to collagen density." Breast Cancer Research 18.1 (2016) Link
Scientific Paper Publication: Feng, Zipei, et al. "Multispectral Imaging of T and B Cells in Murine Spleen and Tumor." The Journal of Immunology 196.9 (2016): 3943-3950 Link
Scientific Paper Publication: Woods, Katherine, et al. "Mismatch in epitope specificities between IFNγ inflamed and uninflamed conditions leads to escape from T lymphocyte killing in melanoma." Journal for immunotherapy of cancer 4.1 (2016) Link
Scientific Paper Publication: Huang, Fangjin, et al. "Quantitative imaging for development of companion diagnostics to drugs targeting HGF/MET." The Journal of Pathology: Clinical Research (2016) Link
Scientific Paper Publication: Ören, Bilge, et al. "Tumour stroma-derived lipocalin-2 promotes breast cancer metastasis." The Journal of Pathology (2016) Link
Scientific Paper Publication: Linch, Stefanie N., et al. "Combination OX40 agonism/CTLA-4 blockade with HER2 vaccination reverses T-cell anergy and promotes survival in tumor-bearing mice." Proceedings of the National Academy of Sciences 113.3 (2016): E319-E327 Link
Scientific Paper Publication: NEJM: PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma Link
Scientific Paper Publication: Novartis Genoptix Shows Multiplexed IHC Test Better Predicts Immunotherapy Response Link
Scientific Paper Publication: Miecnik, Bernhard, et al. "The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis." Science translational medicine 8.327 (2016) Link
Scientific Poster Poster: Optimization Strategy For Fluorescence Multiplex Immunohistochemistry Tissue Staining Link
Scientific Poster Poster: Automate Your Complete Cancer Research Workflow with Phenoptics™ Link
Webinars Webinar: Using multiplexed IHC to Effectively Navigate the Hidden Clues of the Immunological Microenvironment Link