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HypoxiSense 680 Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 

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NEV11070 561.00 USD

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Overview

Hypoxia occurs in tumors as a result of the poor ability of their disorganized vascular networks to deliver blood borne oxygen. HypoxiSense™ 680 fluorescent imaging agent detects the tumor cell surface

expression of carbonic anhydrase 9 (CA IX) protein, which increases in hypoxic regions within many tumors, especially in cervical, colorectal, non-small cell lung tumors. Pairing HypoxiSense with optical fluorescent imaging technology allows you to image and quantitate tumor sub-regions undergoing hypoxia-related changes, non-invasively and in vivo.

HypoxiSense in vivo imaging reagent is ideally suited for detecting hypoxia-induced changes in CA IX expression during:

  • Imaging in vivo mouse and rat tumors
  • Assessing therapeutic efficacy in drug screening of tumor models
  • Fluorescence microscopy of disease tissues

For the first time, hypoxia can be measured non-invasively in living mice and rats, as well as in ex vivo tissue samples. It's the perfect solution for the in vivo hypoxia researcher.

Disclaimer: For laboratory use only. This product is intended for animal research only and not for use in humans.

Specifications

Fluorescent Agent Type Targeted
Optical Imaging Classification Fluorescence Imaging
Product Brand Name HypoxiSense
Shipping Condition Blue Ice
Therapeutic Area Oncology/Cancer, Arthritis, Angiogenesis
Unit Size 1 Vial (10 doses)
Wave Length 680 nm

Tools

Resources, Events & More

Resource Type File Name File Format
Brochure HypoxySense 680 (Product Sheet) PDF 546 KB
Brochure In Vivo Imaging Agents Brochure PDF 2 MB
Technical Note HypoxiSense 680 (Data Sheet) PDF 170 KB
Technical Note HypoxiSense 680 (Protocol) PDF 257 KB
Citations Library View peer reviewed publications using PerkinElmer's In Vivo Imaging Reagents Link