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GSP Neonatal 17á-OH-progesterone kit

The GSP Neonatal 17α-OH-progesterone assay is intended for the quantitative determination of 17OHP in dried blood spot specimens as an aid in screening newborns for CAH.

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Product Number
3305-001U

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Overview

Congenital adrenal hyperplasia (CAH) is a genetic disorder and the most severe form of the disease can lead to a life threatening condition during the first weeks of life. The disease is caused by enzyme defects in steroid biosynthesis, the most frequent types being 21- and 11a-hydroxylase deficiency. These types represent 95% of CAH cases and in both, the 17a-OH progesterone (17OHP), a precursor of cortisol, is increased. The determination of 17OHP is thus a useful screening method for 95% of all CAH cases.

GSP Neonatal 17a-OH-progesterone assay:

  • Incubation time 3 h
  • Sensitive, robust DELFIA chemistry for confidence in results
  • All reagents are ready to use
  • Contains reagents and plates for 1152 tests (12 plates)

The GSP Neonatal 17a-OH-progesterone assay is based on the competitive binding of europium-labeled 17OHP and 17OHP in the sample to 17OHP-specific antibodies. The fluorescence signal is inversely proportional to the analyte concentration in the sample.

All PerkinElmer neonatal products may not be available in all countries.

Disclaimer: US only

Specifications

Assay Technology DELFIA
Calibration Standards Yes
Detection Method DELFIA
Disorders Congenital Adrenal Hyperplasia (CAH)
Product Brand Name GSP®
Unit Size 1 Kit

Tools

Resources, Events & More

Resource Type File Name File Format
Support Page Newborn screening website Link