Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
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Glomerular filtration rate (GFR) is the gold standard in kidney function assessment and is used to determine progression of kidney disease and drug-induced kidney toxicity. One of the most accepted ways to assess GFR is by measuring the rate of disappearance of labeled inulin from the blood; as inulin is completely filtered at the kidneys’ glomeruli (but neither secreted nor reabsorbed by the tubules), this rate of disappearance is directly proportional to GFR. We offer a near infrared (NIR) fluorescent-labeled form of inulin (GFR-Vivo 680) in a spectral region providing low background and high tissue penetration (ex/em = 670/685 nm) for in vivo applications.
Disclaimer: For laboratory use only. This product is intended for animal research only and not for use in humans.
|Fluorescent Agent Type||Vascular|
|Optical Imaging Classification||Fluorescence Imaging|
|Product Brand Name||GFR-Vivo|
|Shipping Condition||Blue Ice|
|Unit Size||1 Vial (10 doses)|
|Wave Length||680 nm|
|Resource Type||File Name||File Format|
|Brochure||In Vivo Imaging Agents Brochure||PDF 2 MB|
|Application Note||In Vivo Non-Invasive Method to Determine Glomerular Filtration Rate (GFR)||PDF 2 MB|
|Data Sheet||GFR-Vivo 680 (Data Sheet)||PDF 204 KB|
|Poster||In Vivo NIR Imaging and Quantification of Glomerular Filtration Rate (GFR) in Mice||PDF 2 MB|
|Poster||Novel near Infrared Agent for Noninvasive Imaging and Quantification of Glomerular Filtration Rate in Mice||PDF 2 MB|
|Citations Library||View peer reviewed publications using PerkinElmer's In Vivo Imaging Reagents||Link|
|Webinar||A Novel Non-Invasive NIR Imaging Agent (GFR-Vivo 680) for Measurement of Glomerular Filtration Rate in Mice - View On Demand||Link|