Human fibrinogen, labeled with 125I. Fibrinogen is a glycoprotein that promotes blood clotting by activating blood platelets through binding to their GpIIb/IIIa surface membrane fibrinogen receptor.
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We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.
Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
|Fresh Lot Days||Fourth Monday of each Month|
|Label Position||Nominally Labeled|
|Product Brand Name||NEN Radiolabeled Ligands|
|Special Ordering Information||This is a radioactive product - shipping address must have a license to receive radioactive materials.|
|Therapeutic Area||Cardiovascular, Inflammation, Metabolic Disorders|
|Unit Size||110 µCi|