PerkinElmer
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[125I]- Epidermal Growth Factor (h, r), 25 µCi

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.

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Unit Size
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NEX428005UC
5 µCi
725.00 USD
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NEX428025UC
25 µCi
1599.00 USD
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Detail Information

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX428:

  1. Gosney J.A., Ceresa B.P. (2017) Using Percoll Gradient Fractionation to Study the Endocytic Trafficking of the EGFR. In: Wang Z. (eds) ErbB Receptor Signaling. Methods in Molecular Biology, vol 1652. Humana Press, New York, NY.

Specifications

Detection Method Radiometric
Fresh Lot Days Third Monday of each month
Label Position Nominally Labeled
Molecular Weight 6000.0
Product Brand Name NEN Radiolabeled Ligands
Radioisotope I-125
Radionuclide 125I
Receptor Type Epidermal Growth Factor
Shipping Condition Dry Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area Cancer
Unit Size 25 µCi