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EnVision Multilabel Plate Reader

The EnVision Multilabel Plate Reader provides the highest speed, ultra-high throughput, and maximum sensitivity across  all detection technologies, so that your high throughput screening applications won’t be held back by unreliable results or equipment that can’t keep up to the demands of escalating workloads and new assays.

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  • Our state-of-the-art, dual-detector model is among the fastest HTS readers in the market
  • Choose from 12 technologies including AlphaScreen®, AlphaLISA®, fluorescence, ultra-sensitive luminescence, absorbance, time-resolved fluorescence (TRF) and TR-FRET, for example to detect PerkinElmer’s DELFIA and LANCE assay technologies
  • Maximum speed and sensitivity with proprietary Direct Optics™ technology
  • Hybrid system combining filters for sensitivity and monochromators for assay flexibility
  • Laser excitation technology for time-resolved fluorescence modes for the best available TRF performance
  • Laser technology for high throughput for AlphaScreen assays
  • Low detection levels for high throughput screening applications so you can be confident that you are not missing any leads.

Together with application expertise, reagents and automation, PerkinElmer offers a complete solution to your lab’s needs.

Make the most of your high-quality data generated using the EnVision Multilabel Plate Reader by harnessing the advanced data visualization and analysis capabilities of TIBCO Spotfire®. Our Spotfire® Analyst for Multimode Detection (MMD) package is tailored to the analysis of plate reader data and enables you to visualize, correlate, compare and analyze your data and share freely with your colleagues.

Two configurations are available, which both offer the same unsurpassed sensitivity and analytical performance.

  • The EnVision Multilabel Plate Reader - a super-fast, dual-detector reader designed specifically to support demanding high-throughput discovery applications.
  • The EnVision Xcite Multilabel Plate Reader – a single-detector system ideal for the most challenging research and assay development applications. The EnVision Xcite Multilabel Plate Reader is upgradeable to the EnVision Multilabel Plate Reader.

Technologies included:

  • Filter based fluorescence intensity (top and bottom)
  • Time-resolved fluorescence
  • Luminescence, including glow, flash and dual luminescence
  • Filter-based absorbance
  • Fluorescence Polarization

Optional technologies:

  • Standard AlphaLISA®/AlphaScreen® (Laser excitation)
  • High-throughput AlphaLISA®/AlphaScreen® (Laser excitation)
  • Monochromator-based fluorescence intensity (top and bottom)
  • Monochromator-based absorbance detection
  • Laser-based time-resolved fluorescence
  • Ultra sensitive luminescence

Key Features:

  • Proprietary Direct Double Optics™ deliver a full lens system for maximum speed and sensitivity (EnVision only)
  • The fastest mode uses an innovative "on the fly"-detection - making EnVision exceptionally fast in measuring absorbance or fluorescence intensity on a 1536-well plate - less than 36 seconds including plate loading times
  • Field upgradeable for changing application needs
  • User-changeable, label-specific optical mirror modules and filters for assay customization with positive identification of measurement configuration (barcodes)
  • Integrated barcode reading enables barcode reading from short right side and both long sides of the plate
  • Optional 21 CFR Part 11 support


  • 2 channel dispenser
  • Plate stacker (20 or 50 plates)
  • Temperature control up to 65º C
  • Compatible with a wide range of automation systems

Disclaimer:  For research use only. Not for use in diagnostic procedures.


21 CFR Part 11 Compatible Yes
Automation Compatible Yes
Detection Method Absorbance, Time-Resolved Fluorescence (TRF), Luminescence, Alpha, Fluorescence, Fluorescence Polarization
Product Brand Name EnVision

Resources, Events & More

All (21)
Resource Type File Name File Format
Brochure Drug Discovery Screening Solutions Brochure PDF 880 KB
Brochure EnVision Multilabel Plate Reader Brochure PDF 2 MB
Brochure Multimode Plate Reader Portfolio Brochure PDF 1 MB
Application Note Advantages of Wavelength Scanning in Fluorescence and Absorbance Assays PDF 393 KB
Application Note AlphaLISA GMO Protein Detection Seed Extract PDF 1 MB
Application Note Performing AlphaLISA Assays with RPMI-1640 PDF 604 KB
Application Note α-Fetoprotein Assay on Dried Blood Spot for Hepatoblastoma Screening in Children with Overgrowth-Cancer Predisposition syndromes PDF 199 KB
Technical Note Enhancement of BRET2 Assay Robustness and Handling Utilizing the PerkinElmer EnVision Plate Reader PDF 975 KB
Technical Note Normalization of Luminescence Assays Using Glowell Microplate Standards, ATPLite Luminescence Assay Kit and EnVision Multilabel Plate Readers PDF 530 KB
Technical Note Photometric Assays with Envision Multilabel Plate Reader PDF 312 KB
Poster AlphaLISA Quantification and Characterization of BioTherapeutic Proteins and Process Contaminants PDF 653 KB
Poster AlphaLISA® Technology and the SciStream™ Add-on for TIBCO Spotfire® PDF 1 MB
Poster Characterization of Intractable Epigenetics Targets Using Homogenous Immunoassays PDF 1 MB
Poster Comparison of endogenous methyl marks on histone H3 in cancer-derived cell lines using AlphaLISA PDF 1 MB
Poster Development of New AlphaLISA No-wash Immunoassay Kits for Sensitive, Rapid and Efficient Quantification of Cytokines PDF 279 KB
Poster Efficient AlphaLISA immunoassays for the detection and characterization of monoclonal antibody biotherapeutics PDF 525 KB
Poster High Sensitivity cAMP Assays in Primary Cells and Mesenchymal Stem Cells with the LANCE® Ultra cAMP kit PDF 114 KB
Poster Simultanous detection of IL-6 and IL-8 secretion by cell lines using Alpha technology PDF 528 KB
Poster Tau Duplex: A novel assay to detect phosphorylated and total tau protein in neuronal cells using Alpha technology PDF 515 KB
Poster Use of the JANUS Automated Workstation to Develop Efficient AlphaLISA Immunoassays for Isotyping Human Monoclonal Antibodies PDF 1 MB
Application Note Simultaneous Detection of Total and Phosphorylated Protein in Cellular Kinase Assays Link