Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
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Cat B 680 FAST™ is a member of a family of activatable fluorescent imaging agents comprising a novel architecture, termed F.A.S.T. (Fluorescent Activatable Sensor Technology) that confers an improved pharmacokinetic profile with a broader range of early imaging time points. This architecture also offers higher target specific signal with reduced background.
Cat B 680 FAST is a Cathepsin B activatable fluorescent agent that is optically silent upon injection and produces fluorescent signal after cleavage by Cathepsin B produced by inflammatory cells and tumor cells. Cat B 680 FAST may be used to monitor inflammation, tumor activity, progression of disease and the efficacy of therapeutic treatment in applications such as oncology, inflammation, cardiovascular disease and some neurological diseases.
Disclaimer: For laboratory use only. This product is intended for animal research only and not for use in humans.
|Fluorescent Agent Type||Activatable|
|Optical Imaging Classification||Fluorescence Imaging|
|Product Brand Name||Cat B FAST|
|Therapeutic Area||Atherosclerosis, Oncology/Cancer, Arthritis, Inflammation|
|Unit Size||1 Vial (10 doses)|
|Wave Length||680 nm|
|Resource Type||File Name||File Format|
|Brochure||FMT Fluorescence Tomography in vivo Imaging Systems||PDF 1 MB|
|Brochure||In Vivo Imaging Agents Brochure||PDF 2 MB|
|Application Note||In Vivo Imaging of Atherosclerosis Disease Using FMT||PDF 1 MB|
|Technical Note||Cat B 680 FAST (Protocol)||PDF 252 KB|
|Technical Note||Cat B 680 FAST™ (Data Sheet)||PDF 192 KB|
|Poster||A novel NIR dye for in vivo temporal tracking of labeled macrophages to sites of acute inflammation||PDF 689 KB|
|Poster||Non-Invasive Quantitative Tomography of Disease Progression and Therapeutic Response||PDF 581 KB|
|Citations Library||View peer reviewed publications using PerkinElmer's In Vivo Imaging Reagents||Link|