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ANGIOTENSIN I (human), [125I]Tyr4-, 50µCi (1.85MBq), Species Activity:2200Ci (81.4TBq/mmol)

Angiotensin I, labeled with 125I on the tyrosine (Tyr4) residue. Angiotensin I is the precursor to Angiotensin II, which a peptide hormone that causes vasoconstriction and increased blood pressure, and is a potential drug target for blood pressure regulation.

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Part Number Unit Size List Price Your Price Quantity
NEX101010UC 10 µCi 857.00 USD
NEX101050UC 50 µCi 2054.00 USD
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We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX101:

  1. Aurell, M., Pettersson, M., Berglund, G. Renin-Angiotensin System in Essential Hypertension. The Lancet, Volume 306, Issue 7930, 1975, Pages 342-345.


Detection Method Radiometric
Fresh Lot Days First Monday of each month
Label Position Nominally Labeled
Product Brand Name NEN Radiolabeled Ligands
Radioisotope I-125
Radionuclide 125I
Shipping Condition Ambient
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area Angiogenesis, Cardiovascular
Unit Size 50 µCi

Resources, Events & More

Resource Type File Name File Format
Technical Note Low Volume Handling Suggestions for Iodine-125 Labeled Compounds PDF  177 KB
Flyer Using the NENSure Packaging System from PerkinElmer PDF  447 KB