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AequoScreen Plasmid (+Gα16)

The aequorin plasmid, which expresses the aequorin protein under the control of the CMV promoter, has been developed to convert mammalian cell lines into AequoScreen compatible cell lines.

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ES-003-AC 26200.00 USD

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Overview

The aequorin plasmid (+Ga16), which expresses the aequorin protein and the promiscuous G alpha16 protein under the control of the CMV promoter, has been developed to convert mammalian cell lines into AequoScreen® compatible cell lines. It is a powerful tool for the rapid development and analysis of cell lines, already expressing a recombinant or endogenous G-Protein coupled receptor of choice, to a luminescence readout. The aequorin plasmid (+Ga16) particularly addresses GPCRs of the Gs and Gi family enabling them to modulate intracellular calcium concentration. Terms and conditions apply.

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Specifications

Assay Target Type Cell line
Assay Validated Calcium Luminescence
G-Alpha Coupling Protein Ga16
Product Brand Name AequoScreen
Second Messenger Release Calcium flux
Shipping Condition Dry Ice
Unit Size 10 µg