Stem cells can now be grown and transformed into specialized cells with characteristics consistent with cells of various tissues such as muscles or nerves through cell culture.
EnlargeMouse embryonic stem cells forming stem cell colonies on a fibroblast feeder layer. Stained with Hoechst 33342, Cytokeratin and Oct-4, imaged on Operetta®
Stem cell research has the potential to make a huge impact on a wide range of human health problems. Stem cell research could facilitate the development of new treatments for human diseases such as diabetes and Parkinson’s, aid the treatment and prevention of medical conditions resulting from abnormal cell division and cell differentiation, and enable the testing of new drugs without the need for animals or human testers. It could also provide a renewable source of replacement cells and tissues to treat diseases such as Alzheimer's disease, stroke, heart disease, osteoarthritis and rheumatoid arthritis.
Cellular imaging has a crucial role to play in stem cell research as it enables scientists to visualize and analyze these complex cellular processes. Identifying and characterizing cells in their various stages of development, from pluripotent embryonal cell to progenitors and differentiated organ specific cells, and to distinguish them from surrounding stroma, is a recurring task – from basic research to quality control of transplants.
For this fast paced area of research, PerkinElmer provides state-of-the-art imaging and high content screening solutions to stem cell researchers all over the world. Our dedicated team of imaging specialists have an in-depth understanding of the imaging-based stem cell applications and will help you choose the right solution for your research requirements.