Operetta

High Content Imaging System for unbiased results

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As scientists try to answer increasingly complex biological questions, they need to conduct imaging experiments on a larger scale. But analyzing samples manually can be a long and difficult process , increasing the chance of producing biased data.

That’s why more scientific researchers are turning to high throughput biology, where automation meets cellular biology. And why they rely on the Operetta® High Content Imaging System, the superior solution for delivering it.

Stunning image quality. See all the possibilities.

  • High numerical aperture objectives give exceptional images for higher quality data and reliable results
  • Widefield and confocal options give you the choice of high speed, high content screening or background suppression to examine small cellular features and planes in 3D samples
  • Unsupervised automated image acquisition and autofocus for reliable high content imaging from slides to multiple plates
  • Low and high magnification plus a large field of view allows you to look at the whole well and choose an area of interest for detailed analysis
  • Compatible with our range of imaging microplates for the best quality images

1.) Mouse embryonic stem cell colonies after 3 days of culturing imaged on Operetta 2.) Mouse embryoid body imaged on Operetta 3.) HeLa cells expressing an anti-Lamin-Chromobody imaged on Operetta. 4.) Mouse embryonic stem cell colonies growing on a fibroblast feeder layer imaged on Operetta

Software in harmony with your research goals

  • Easy to set up assays, automate experiments, analyze data and store, retrieve and present results, making it ideal for the multi-user, multi-departmental environment
  • Intuitive Harmony® High Content Imaging and Analysis Software makes it easy for biologists to turn their biology into unbiased quantitative data
  • Ready-made solutions for a range of common applications enable new users to get started with high content image analysis right away using the pre-configured sequences
  • User-configurable image analysis building blocks  for  easy creation of customized high content analysis applications
  • Texture analysis for applications where intensity and morphology are not suitable or do not deliver robust readout and reproducible results giving you a more complete picture of your biology
  • Transfer and view data from any computer that has Harmony High Content Imaging and Analysis Software
  • PhenoLOGIC™ machine learning option enables you to teach the software to create optimized algorithms for your experiment, making tailored image analysis easier

Flexibility and ease for all your applications

  • Suitable for a wide range of fixed and live cell applications - view our Operetta application notes and see for yourself
  • Live cell chamber option to maintain environmental conditions (temperature, CO2) for live cell samples
  • Kinetic capabilities for carrying out time course experiments for a better understanding of cellular events
  • Integrates with our robotic automation platforms for a fully automated solution enables you to teach the software to create optimized algorithms for your experiment, making tailored image analysis easier
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