Reporter gene assays have easily measurable phenotypes that form the basis of sensitive, quantitative and reproducible assays of eukaryotic gene expression and regulation. Specifically, researchers can use reporter genes to characterize the strength of promoters and enhancers, define the role of transcription factors, assess transfection efficiency or the like. Fluorescent proteins are the most common fluorescent probes for imaging-based reporter gene assays.
Our Reporter Gene Assay Solutions
Drawing on many years of experience and in-depth knowledge, PerkinElmer offers solutions for every throughput, a starting point for typical infection assays and unlimited possibilities for customization:
Opera High Content Screening System
- High sample throughput with multi-color parallel image acquisition and over 100,000 data points per day
Operetta Compact High Content Screening System
- High speed with large field of view and large cell number captured with every image
- Ready-made image analysis sequences for protein expression in cytosol, on plasma membrane and in nucleus, including documentation on how to customize
- Unlimited possibilities for adding parameters and modifying readout
Acapella Image Analysis Software
- Image analysis sequences for protein expression in cytosol, on plasma membrane and in nucleusÂ
- Unlimited possibilities for adding parameters and modifying readout
Columbus High Volume Data Management and Analysis System
- Enterprise level data management from assay development to high throughput screening seamlessly linking high content data, research data, in vivo imaging data, result management, screening statistics, biological and chemical data
cell::explorer Automated High Content Screening System ing System
- Full environmental control and workstation with hand-over of plates from imager to incubator for short-term and long-term live cell assays
- Scalable and fully automated workstation including compound handling, reagent addition, incubation, cell fixation and staining
- Instruments with readout other than imaging can be included, such as whole well fluorescence / luminescence (e.g. EnVision, EnSpire)
You may also be interested in: Live Cell Imaging.