The DNA Sequencing and Analysis Services can provide three different levels of bioinformatics support for your sequencing applications, depending on your specific needs.
For all three levels we provide total data security, whether we deliver your data on disk, or through our web-based portal to our private cloud environment. We also partner with Geospiza, GenomeQuest and Knome for further downstream annotation and analysis.
- Level 1 Bioinformatics - provides you with FastQ files from your run data, delivered on hard disk
- Level 2 Bioinformatics - provides you with FastQ files, plus alignment to reference using BWA and variant list based upon SAMtools or GATK
- Level 3 Bioinformatics - provides on-line access to data, in silico filtering of results, visualization of coverage, multi-sample comparisons and review of annotation
EnlargeStandardized Data Processing: “Push button” processing allows incorporation of many bioinformatic steps into a pipeline using best-practices settings, resulting in an annotated listing of sequence variations (including SNVs and InDels). Processing occurs in our unique, client specific, private analysis clusters insuring total data security.
EnlargeEnlargeGene Based Browsing: our default pipeline annotates reads by gene name allowing graphical overview of exon coverage, and visual localization of detected sequence variants within that gene. This allows a researcher to quickly access the data that is most relevant to their study.
EnlargeUser Filterable Variant Lists: detected variants are annotated for key criteria allowing rapid reduction of large number of variants down to those of most interest to the researcher. In-silico filtering via a web browser requires no software to be installed by the client and secure access to results from any web connected computer.
EnlargeDetailed Read Alignments: a quality coded alignment view allows assessment of the context of individual variants.