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Zirconium-89-Monday Calibration

Visualize and quantify uptake of monoclonal antibodies (mAbs) using Zirconium-89 (89Zr). With a long-lived half-life of (3.3 days), 89Zr is well suited as a PET Imaging biomarker to access target expression as well as tumor targeting of mAbs.

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Part Number SKU Display Name
NEZ308000MC Zirconium-89-Monday Calibration
NEZ308A000MC Zirconium-89-Tuesday Calibration
NEZ308B000MC Zirconium-89-Wednesday Calibration
NEZ308C000MC Zirconium-89-Thursday Calibration
NEZ308D000MC Zirconium-89-Friday Calibration

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Overview

Zirconium-89 radionuclide, dispensed for Monday* calibration. 89Zr is particularly suitable for PET imaging of internalizing mAbs. This calibration date is currently only available outside North America. 89Zr-immuno-PET can offer excellent sensitivity and accurate quantification of mAbs or mAb-fragments in pre-clinical in vivo models. 89Zr's physical half-life of 78.4 hr matches the biological half-life of a mAb, as well as the time it needs to perfectly reach optimal target-to-non-target ratios. Literature suggests that PET image quality is not disturbed by the decay of this residualizing isotope.

  • NEZ308000MC (Monday calibration) is manufactured at a GMP-compliant Facility
    • Compliant with GMP Directive 2003/94/EC Part 2 and ICHQ7 for Active Pharmaceutical Ingredients, August 2001.
    • Quality tested to ensure consistency

    *Monday calibration date available only outside North America.

Specifications

Detection Method Radiometric
Product Brand Name NEN Radiochemicals
Quantity in a Package Amount 1.0 per pack
Radioisotope Zr-89
Radionuclide 89Zr
Shipping Condition Ambient
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Unit Size mCi