High Content Analysis (HCA) and High Content Screening (HCS) are imaging based multi-parametric approaches of cell analysis at the single-cell level. Originally developed as a complementary technology to traditional biochemical high-throughput screening (HTS) in drug discovery, today High Content Screening is established in a far broader area of the life science space as an unbiased method of imaging multiple cellular samples.
Harmony: The image acquisition, image analysis and data management software for High Content Screening on the Operetta
High Content Analysis and High Content Screening offer a number of advantages over traditional techniques:
- More information from cellular samples
– fully automated imaging and unbiased image analysis exploits the full potential of microscopy, improving your lab’s throughput and productivity - More meaningful results
– screening can be performed under physiological and biological more relevant conditions than in a classical biochemical scenario - More questions answered simultaneously
– data sets are more information-rich compared to biochemical read-outs, allowing a number of questions to be asked simultaneously
PerkinElmer offers a full range of solutions for High Content Analysis and High Content Screening that can be tailored by our team of experts to meet your lab’s needs:
- Opera High Content Screening System
- Acapella Image Analysis Software
- Operetta Compact High Content Screening System
- Columbus High Volume Data Management and Analysis System
- cell::explorer Automated High Content Screening System