Infectious Diseases

HCS plays a significant role in infectious disease research as it enables high throughput functional and phenotypic assays that can be adapted to a wide range of pathogens including virus, bacteria and eukaryotic parasites. Applications include genetic siRNA interference screens for identifying host factors involved in host–pathogen interactions, but also screens for lead discovery in drug discovery. High-content analysis enables, for example, intracellular tracking of viral particles to profile the antiviral mechanisms of each compound and sensitive measurements of bacterial infection rates. Adaptation to high-throughput screening in bacteriology and parasitology has already led to the discovery of new types of host-specific inhibitors that differ from those inhibitors that act directly on microbes.

Customer Stories

Unravelling the Zika Virus

Publications using PerkinElmer High-Content Screening Products

For Research Use Only. Not for Use in Diagnostic Procedures.