For Research Use Only. Not for Use in Diagnostic Procedures.
Cell Shape Changes
The shape of a cell can change in response to many different stimuli. The rounding up of cells from an attached and spread-out state on a substrate, for example, can be observed when cells are dividing or experiencing toxic effects.
Analysis of cell spreading is relevant to screening for inhibitors of cell adherence to a substrate. Common measures of the cell shape are area, roundness and width to length ratio.
Morphology parameter ‘length’, visualized for each individual cell in a population.