PerkinElmer
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Nucleic Acid Analysis and Protein Characterization

Utilizing automated microfluidic capillary electrophoresis (micro-CE) technology, our instruments enable the user to simplify the process of traditional gel separations, resulting in even more accurate and reproducible data in a fraction of the time. Separate, identify and analyze genomic and protein samples in seconds and visualize your data as an electropherogram, virtual gel, or tabular report.

  • The LabChip® GX Touch nucleic acid analyzer performs DNA/RNA separation and analysis with minimal concentration requirements. This platform is ideal for NGS applications including cfDNA, FFPE, and PCR-free DNA quantitation.
  • The LabChip® GXII Touch protein characterization system makes protein quantitation fast with capillary electrophoretic separation. Detect, quantitate, and assess protein purity for biotherapeutic research with confidence that data is accurate and reproducible.
For research use only. Not for use in diagnostic procedures.

Applications

DNA and RNA Analysis with Microfluidics Technology

Microfluidic Electrophoresis Analysis

The LabChip® GX Touch microfluidics technology is an unparalleled electrophoresis platform that offers high sensitivity nucleic acid analysis including: gDNA and RNA integrity assessment, library preparation quality assurance, and PCR fragment sizing and quantitation. Used in many applications including cell free DNA research, CRISPR modelling, and PCR-free library preparation, the LabChip GX Touch system quantifies DNA at concentrations as low as 2pg/uL.

  • Flexible throughput - from 1 to 384 samples per run
  • Reusable chips - up to 2000 samples
  • Choice of data output - electropherogram, virtual gel and data table format
  • Easy to use software - 21 CFR Part 11 compliant and IQ/OQ installation available

For research use only. Not for use in diagnostic procedures.

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Microfluidic Protein Characterization Analysis

Microfluidic Electrophoresis Analysis

Proteins differ from each other in their size, molecular structure and physiochemical properties. These differences allow for protein analysis and characterization by separation and identification. The LabChip® GXII Touch protein characterization system offers rapid peak quantification and quality control throughout the protein purification workflow.

The platform supports multiple assays for characterizing proteins in reduced and non-reduced samples including:

  • Analyze critical quality attributes in as few as 42 seconds:
  • Titer (concentration and sizing)
  • Purity assessment
  • Aggregation (covalently linked)
  • Stability (degradation / fragmentation analysis)
  • N-Glycan profiling
  • mAb Charge variant / charge heterogeneity
  • mAb impurity analysis (detect minor impurities)

Analysis can be performed in as few as forty seconds per sample that deliver comparable data to traditional capillary electrophoresis with as much as a 70X increase in throughput. Choose 96-well or up to 384-well platforms depending upon throughput needs. With an easy to use touch screen interface, even occasional users get up and running samples quickly.

For research use only. Not for use in diagnostic procedures.

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Automated Solutions

LabChip GXII Touch HT Protein Characterization System

The LabChip® GXII Touch protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Leveraging microfluidic electrophoretic separation technology, the LabChip® GXII Touch system enables rapid characterization with minimal sample preparation setup and sample input volume.

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LabChip GX Touch Nucleic Acid Analyzer

DNA and RNA quantitation and sizing can be done in seconds using automated capillary electrophoresis separation. The LabChip® GX Touch nucleic acid analyzer’s microfluidic technology generates reproducible, high-resolution data and is optimal for
  • NGS library preparation (smear and fragment analysis) and quality control
  • RNA and DNA fragment analysis (including cell-free (cfDNA), FFPE, liquid biopsy, and PCR-free samples)
  • Quantitation and qualification for CRISPR fragment analysis
  • Agarose gel workflows

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