Tissue Biomarker Reagents

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Reliably detect and quantify proteins and nucleic acids that often cannot be measured with standard methods. Our Tyramide Signal Amplification reagent kits improve your current Immunohistochemistry, (IHC), immunofluorescence (IF) or in situ hybridization (ISH) protocol using your existing imaging hardware, any microscope, any sample.

We also offer reagent kits or simultaneous detection of up to six protein biomarkers plus nuclear counterstain, within a single image. The workflow is similar to standard immunohistochemistry. It allows use of the best primary antibodies together for multiplexed results without fear of cross-reactivity based on the host species. Assay targets include CD20, CD4, CD45RO, CD68, FOXP3, panCK, and other custom targets.

For research use only. Not for use in diagnostic procedures.

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Application
  • Immunohistochemistry (IHC) (33)
  • In situ hybridization (ISH) (25)
Assay Target
  • CD20 (3)
  • CD4 (4)
  • CD45RO (1)
  • CD68 (2)
  • CD8 (4)
  • FOXP3 (2)
  • panCK (2)
Automation Compatible
  • No (4)
Detection Method
  • Chromogenic (6)
  • Fluorescence (36)
  • MSI (3)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy3.5 (1)
  • Cy5 (4)
  • Cy5.5 (1)
  • DAPI (4)
  • Fluorescein (6)
  • Opal 520 (8)
  • Opal 540 (6)
  • Opal 570 (7)
  • Opal 620 (6)
  • Opal 650 (4)
  • Opal 670 (2)
  • Opal 690 (6)
  • TMR (5)
Format
  • Microplates (3)
  • Slides (26)
Imaging Modality
  • Multispectral Imaging (4)
Product Brand Name
  • Ancillary Products (8)
  • HCA ImagAmp (3)
  • Opal (8)
  • TSA (13)
  • TSA Plus (15)
Target Species
  • Human (4)
Volume
  • 0-50 (5)
  • 101-150 (1)
  • 201-250 (1)
Volume Capacity
  • 150 µL (2)
  • 250 mL (1)

"Tissue Biomarker Reagents" 1-48 of 48 Products and Services

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Opal Polymer HRP Ms Plus Rb, 1X, 25 mL

Opal Polymer HRP Ms + Rb is a ready-to-use immunohistochemistry detection reagent specifically optimized for use with Opal and TSA® Plus detection reagents for maximum sensitivity, reduced incubation time and low background. This product reacts specifically with primary antibodies raised in mouse and rabbit and is part of a rapid, biotin-free detection protocol.
List Price : 289.00 USD

OPAL 5-color fIHC Kit

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.
Price Range : 913.00 USD - 3970.00 USD

Opal 4 Lymphocyte Panel Kit

The Opal™ 4 Tumor Lymphocyte Kit enables phenotyping of helper T cells, cytotoxic T cells and B cells within intact FFPE tissue sections.
List Price : 1598.00 USD

OPAL 7-color fIHC Kit

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.
Price Range : 1290.00 USD - 5600.00 USD
TSA -Plus Cyanine 3 System

TSA Plus Cyanine 3

TSA® Plus Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.
Price Range : 233.00 USD - 1863.00 USD

TSA Plus Fluorescein

TSA® Plus fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 233.00 USD - 1863.00 USD

Opal Polymer HRP Ms Plus Rb, 1X, 50 mL

Opal Polymer HRP Ms + Rb is a ready-to-use immunohistochemistry detection reagent specifically optimized for use with Opal and TSA® Plus detection reagents for maximum sensitivity, reduced incubation time and low background. This product reacts specifically with primary antibodies raised in mouse and rabbit and is part of a rapid, biotin-free detection protocol.
List Price : 437.00 USD

HCA ImagAmp 647 Kit

HCA ImagAmp kits for amplified detection of fluorescent signal in high content screening (HCS) applications.
Price Range : 425.00 USD - 1863.00 USD

TSA Plus Biotin

TSA® Plus Biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 397.00 USD - 1489.00 USD

Opal 4-color IHC Kit

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.
Price Range : 729.00 USD - 3177.00 USD

AR6 buffer, 10X

10X buffer for use in Opal™ immunohistochemistry multiplexing protocols.
Price Range : 62.00 USD - 195.00 USD
TSA -Plus Tetramethylrhodamine System

TSA Plus TMR

TSA® Plus tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.
Price Range : 425.00 USD - 1863.00 USD
TSA Plus DNP (AP)System

TSA Plus DNP (AP)

TSA® Plus DNP (AP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP alkaline phosphatase, with appropriate substrate.
Price Range : 267.00 USD - 477.00 USD

TSA Cyanine 3 Reagent Pack

TSA® Cyanine 3 (Cy3) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 362.00 USD - 1699.00 USD

TSA Plus Cyanine 5.5

TSA® Plus Cyanine 5.5 (Cy5.5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5.5 in the localized area of the probe or antibody.
Price Range : 233.00 USD - 1863.00 USD

TSA Biotin System

TSA® biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 354.00 USD - 1179.00 USD
TSA Cyanine 3/Fluorescein System

TSA Plus Cyanine 3 and Fluorescein System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
List Price : 734.00 USD
TSA -Plus Cyanine 5 System

TSA Plus Cyanine 5

TSA® Plus Cyanine 5 (Cy5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5 in the localized area of the probe or antibody.
Price Range : 233.00 USD - 1863.00 USD

TSA Plus DIG Evaluation Kit

TSA® Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.
Price Range : 225.00 USD - 1489.00 USD

TSA Blocking Reagent

TSA Blocking Reagent is used to make TNB Blocking buffer for use in in situ hybridization (ISH), immunofluorescence (IF), and immunohistochemistry (IHC) procedures. TNB Blocking Buffer is employed for preliminary blocking steps and also as a diluent for antibodies and peroxidase conjugates.
Price Range : 153.00 USD - 483.00 USD

OPAL 6-color fIHC Kit

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.
Price Range : 1101.00 USD - 4812.00 USD

Anti-DNP HRP Conjugate

Anti-DNP antibody conjugated to horseradish peroxidase
List Price : 272.00 USD

TSA Fluorescein System

TSA® fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 453.00 USD - 796.00 USD
TSA Tetramethylrhodamine System

TSA Tetramethylrhodamine System, for 100-300 Slides

TSA® tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.
List Price : 796.00 USD

TSA Plus Cyanine 3.5

TSA® Plus Cyanine 3.5 (Cy3.5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3.5 in the localized area of the probe or antibody.
Price Range : 233.00 USD - 1863.00 USD

Anti-DNP AP Conjugate

Anti-DNP antibody conjugated to alkaline phosphatase
List Price : 321.00 USD
Individual Indirect Tyramide Reagent Pack

TSA Biotin Reagent Pack

TSA® biotin reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 941.00 USD - 4353.00 USD

TSA Plus DNP (HRP)

TSA® Plus DNP (HRP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP hroseradish peroxidase, with appropriate substrate.
Price Range : 267.00 USD - 477.00 USD

Opal 7 Solid Tumor Immunology Kit

The Opal™ 7 Solid Tumor Immunology Kit enables phenotyping of helper T cells, cytotoxic T cells, B cells, macrophages and cancer cells within intact FFPE tissue sections.
List Price : 3390.00 USD

TSA Plus Cyanine 3 System, for 50-150 Slides

TSA® Plus Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.
List Price : 425.00 USD

HCA ImagAmp 546 Kit

HCA ImagAmp kits for amplified detection of fluorescent signal in high content screening (HCS) applications.
Price Range : 425.00 USD - 1863.00 USD

Opal Slide Processing Jar with Lid, 4-pack

Jar for processing slides using the Opal™ protocol for detection of multiple biomarkers in immunohistochemistry (IHC).
List Price : 85.00 USD
TSA Cyanine 3 System

TSA Cyanine 3 System, for 50-150 Slides

TSA® Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.
List Price : 453.00 USD
TSA -Plus TMR/Fluorescein System

TSA Plus Fluorescein and Tetramethylrhodamine (TMR) System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
List Price : 734.00 USD

Antibody Diluent / Block, 1X, 50 mL

This ready-to-use antibody diluent and blocking buffer formulation has been optimized specifically for Opal™ and TSA® Plus immunohistochemistry protocols. It acts to minimize non-specific interaction of antibodies that can be a source of background.
List Price : 74.00 USD

HCA ImagAmp 488 Kit

HCA ImagAmp kits for amplified detection of fluorescent signal in high content screening (HCS) applications.
Price Range : 425.00 USD - 1863.00 USD

Opal 7 Immunology Discovery Panel Kit

The Opal™ 7 Immunology Discovery Kit enables phenotyping of T cells, B cells and macrophages, with 3 open channels for user-selected targets.
List Price : 2678.00 USD
Amplification Diluent

TSA Tetramethylrhodamine Tyramide Reagent Pack, Reagents for 100-300 Slides

TSA® tetramethylrhodamine (TMR) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
List Price : 636.00 USD
TSA Cyanine 3 & 5, TMR, Fluorescein Evaluation Kit

TSA Cy 3, Cy 5, TMR, Fluorescein Evaluation Kit

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
List Price : 472.00 USD

AR9 buffer, 10X

This buffer was developed for use in Opal™ multicolor immunohistochemistry protocol in microwave treatment (MWT) steps.
Price Range : 85.00 USD - 195.00 USD
TSA Coumarin System (100-300 slides)

TSA Coumarin System, for 100-300 Slides

TSA® coumarin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra coumarin in the localized area of the probe or antibody.
List Price : 796.00 USD
TSA Cyanine 3 System/Cyanine 5 System

TSA Plus Cyanine 3 and Cyanine 5 System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
List Price : 734.00 USD

Antibody diluent, 1X, 100 mL

This ready-to-use antibody diluent and blocking buffer formulation has been optimized specifically for Opal™ and TSA® Plus immunohistochemistry protocols. It acts to minimize non-specific interaction of antibodies that can be a source of background.
List Price : 120.00 USD
Amplification Diluent

TSA Cyanine 5 Tyramide Reagent Pack, Reagents for 50-150 Slides

TSA® Cyanine 5 (Cy5) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
List Price : 362.00 USD
TSA Plus Cyanine 5/Fluorescein System

TSA Plus Cyanine 5 and Flourescein System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
List Price : 734.00 USD

TSA Cyanine 5 System, for 50-150 Slides

TSA® Cyanine 5 (Cy5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5 in the localized area of the probe or antibody.
List Price : 453.00 USD

Opal 7 Tumor Infiltrating Lymphocyte Kit

The Opal™ Tumor Infiltrating Lymphocyte Kit enables phenotyping of T cells, B cells and cancer cells within intact FFPE tissue sections.
List Price : 3390.00 USD
Amplification Diluent

TSA Fluorescein Reagent Pack

TSA® fluorescein reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 636.00 USD - 2981.00 USD

"Tissue Biomarker Reagents" 1-48 of 48 Products and Services