Tissue Biomarker Reagents

OF

Reliably detect and quantify proteins and nucleic acids that often cannot be measured with standard methods. Our Tyramide Signal Amplification reagent kits improve your current Immunohistochemistry, (IHC), immunofluorescence (IF) or in situ hybridization (ISH) protocol using your existing imaging hardware, any microscope, any sample.

We also offer reagent kits or simultaneous detection of up to six protein biomarkers plus nuclear counterstain, within a single image. The workflow is similar to standard immunohistochemistry. It allows use of the best primary antibodies together for multiplexed results without fear of cross-reactivity based on the host species.

For research use only. Not for use in diagnostic procedures.

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Application
  • Immunohistochemistry (IHC) (53)
  • In situ hybridization (ISH) (42)
Assay Target
  • CD20 (3)
  • CD4 (4)
  • CD45RO (1)
  • CD68 (2)
  • CD8 (4)
  • FOXP3 (2)
  • panCK (2)
Automation Compatible
  • No (4)
Detection Method
  • Chromogenic (12)
  • Fluorescence (56)
  • MSI (3)
Fluorophore
  • Coumarin (1)
  • Cy3 (9)
  • Cy3.5 (3)
  • Cy5 (6)
  • Cy5.5 (3)
  • DAPI (7)
  • Fluorescein (10)
  • Opal 520 (11)
  • Opal 540 (8)
  • Opal 570 (9)
  • Opal 620 (8)
  • Opal 650 (4)
  • Opal 670 (3)
  • Opal 690 (8)
  • TMR (6)
Format
  • Microplates (6)
  • Slides (44)
Hapten
  • Biotin (6)
  • DIG (3)
  • DNP (4)
Imaging Modality
  • Multispectral Imaging (4)
Product Family
  • Ancillary Products (11)
  • HCA ImagAmp (6)
  • Opal (12)
  • TSA (18)
  • TSA Plus (30)
Target Species
  • Human (4)
Volume
  • 0-50 (5)
  • 101-150 (1)
  • 201-250 (1)

"Tissue Biomarker Reagents" 1-50 of 78 Products and Services

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TSA Plus DIG Evaluation Kit

TSA® Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.

List Price: 225.00 USD

TSA Blocking Reagent

TSA Blocking Reagent is used to make TNB Blocking buffer for use in in situ hybridization (ISH), immunofluorescence (IF), and immunohistochemistry (IHC) procedures. TNB Blocking Buffer is employed for preliminary blocking steps and also as a diluent for antibodies and peroxidase conjugates.

List Price: 483.00 USD

TSA Biotin Tyramide Reagent Pack, Reagents for 200-600 Slides

TSA® biotin reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.

List Price: 941.00 USD

TSA Plus Cyanine 3.5, 250-750 Slides

TSA® Plus Cyanine 3.5 (Cy3.5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3.5 in the localized area of the probe or antibody.

List Price: 1863.00 USD

HCA ImagAmp 647 Reagent Kit, 1 microplate

HCA ImagAmp kits for amplified detection of fluorescent signal in high content screening (HCS) applications.

List Price: 425.00 USD

OPAL 5-color fIHC Kit, 250 slides

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.

List Price: 3970.00 USD

TSA Plus DNP (AP) System, for 25-75 Slides

TSA® Plus DNP (AP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP alkaline phosphatase, with appropriate substrate.

List Price: 267.00 USD

HCA ImagAmp 647 Reagent Kit, 5 microplates

HCA ImagAmp kits for amplified detection of fluorescent signal in high content screening (HCS) applications.

List Price: 1863.00 USD

TSA Biotin Tyramide Reagent Pack, Reagents for 1,000-3,000 Slides

TSA® biotin reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.

List Price: 4353.00 USD
Human lung tumor section processed with the Opal 7 Solid Tumor Immunology Kit

Opal 7 Solid Tumor Immunology Kit

The Opal™ 7 Solid Tumor Immunology Kit enables phenotyping of helper T cells, cytotoxic T cells, B cells, macrophages and cancer cells within intact FFPE tissue sections.

List Price: 3390.00 USD

HCA ImagAmp 488 Reagent Kit, 1 microplate

HCA ImagAmp kits for amplified detection of fluorescent signal in high content screening (HCS) applications.

List Price: 425.00 USD

OPAL 7-color fIHC Kit, 250 slides

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.

List Price: 5600.00 USD

HCA ImagAmp 488 Reagent Kit, 5 microplates

HCA ImagAmp kits for amplified detection of fluorescent signal in high content screening (HCS) applications.

List Price: 1863.00 USD

TSA Plus TMR System, for 50-150 Slides

TSA® Plus tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.

List Price: 425.00 USD

TSA Plus Cyanine 3.5, 50-150 Slides

TSA® Plus Cyanine 3.5 (Cy3.5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3.5 in the localized area of the probe or antibody.

List Price: 425.00 USD

TSA Plus DIG Reagent Kit, 50-150 slides

TSA® Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.

List Price: 397.00 USD

TSA Fluorescein Tyramide Reagent Pack, Reagents for 100-300 Slides

TSA® fluorescein reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.

List Price: 636.00 USD

Opal Polymer HRP Ms Plus Rb, 1X, 50 mL

Opal Polymer HRP Ms + Rb is a ready-to-use immunohistochemistry detection reagent specifically optimized for use with Opal and TSA® Plus detection reagents for maximum sensitivity, reduced incubation time and low background. This product reacts specifically with primary antibodies raised in mouse and rabbit and is part of a rapid, biotin-free detection protocol.

List Price: 437.00 USD

TSA Cyanine 5 Tyramide Reagent Pack, Reagents for 50-150 Slides

TSA® Cyanine 5 (Cy5) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.

List Price: 362.00 USD

AR6 buffer, 10X, 125 mL

10X buffer for use in Opal™ immunohistochemistry multiplexing protocols.

List Price: 62.00 USD

TSA Fluorescein System, for 100-300 Slides

TSA® fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.

List Price: 796.00 USD

TSA Biotin System, for 200-600 Slides

TSA® biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.

List Price: 1179.00 USD

Antibody Diluent / Block, 1X, 50 mL

This ready-to-use antibody diluent and blocking buffer formulation has been optimized specifically for Opal™ and TSA® Plus immunohistochemistry protocols. It acts to minimize non-specific interaction of antibodies that can be a source of background.

List Price: 74.00 USD

TSA Plus Cyanine 5.5, 50-150 Slides

TSA® Plus Cyanine 5.5 (Cy5.5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5.5 in the localized area of the probe or antibody.

List Price: 425.00 USD

Anti-DNP HRP Conjugate

Anti-DNP antibody conjugated to horseradish peroxidase

List Price: 272.00 USD

TSA Plus DNP (HRP) System, for 25-75 Slides

TSA® Plus DNP (HRP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP hroseradish peroxidase, with appropriate substrate.

List Price: 267.00 USD
Human lung tumor section processed with the Opal 7 Immunology Discovery Kit

Opal 7 Immunology Discovery Panel Kit

The Opal™ 7 Immunology Discovery Kit enables phenotyping of T cells, B cells and macrophages, with 3 open channels for user-selected targets.

List Price: 2678.00 USD

Opal 4-color IHC Kit, 50 slides

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.

List Price: 729.00 USD

TSA Plus Cyanine 3 and Cyanine 5 System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.

List Price: 734.00 USD

TSA Cyanine 3 Tyramide Reagent Pack, Reagents for 250-750 Slides

TSA® Cyanine 3 (Cy3) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.

List Price: 1699.00 USD

AR9 buffer, 10X, 250 mL

This buffer was developed for use in Opal™ multicolor immunohistochemistry protocol in microwave treatment (MWT) steps.

List Price: 85.00 USD

OPAL 5-color fIHC Kit, 50 slides

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.

List Price: 913.00 USD

TSA Tetramethylrhodamine Tyramide Reagent Pack, Reagents for 100-300 Slides

TSA® tetramethylrhodamine (TMR) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.

List Price: 636.00 USD

TSA Plus Cyanine 3 System, for 50-150 Slides

TSA® Plus Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.

List Price: 425.00 USD

TSA Plus DNP (AP) System, for 50-150 Slides

TSA® Plus DNP (AP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP alkaline phosphatase, with appropriate substrate.

List Price: 477.00 USD

Opal Polymer HRP Ms Plus Rb, 1X, 25 mL

Opal Polymer HRP Ms + Rb is a ready-to-use immunohistochemistry detection reagent specifically optimized for use with Opal and TSA® Plus detection reagents for maximum sensitivity, reduced incubation time and low background. This product reacts specifically with primary antibodies raised in mouse and rabbit and is part of a rapid, biotin-free detection protocol.

List Price: 289.00 USD

TSA Fluorescein Tyramide Reagent Pack, Reagents for 500-1500 Slides

TSA® fluorescein reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.

List Price: 2981.00 USD

TSA Plus Biotin Kit, 250-750 slides

TSA® Plus Biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.

List Price: 1489.00 USD

Opal Slide Processing Jar with Lid, 4-pack

Jar for processing slides using the Opal™ protocol for detection of multiple biomarkers in immunohistochemistry (IHC).

List Price: 85.00 USD

OPAL 6-color fIHC Kit, 250 slides

Opal™ is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.

List Price: 4812.00 USD

TSA Plus TMR System, for 250-750 Slides

TSA® Plus tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.

List Price: 1863.00 USD

TSA Plus Cyanine 3.5, evaluation kit

TSA® Plus Cyanine 3.5 (Cy3.5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3.5 in the localized area of the probe or antibody.

List Price: 233.00 USD

TSA Cyanine 5 System, for 50-150 Slides

TSA® Cyanine 5 (Cy5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5 in the localized area of the probe or antibody.

List Price: 453.00 USD

TSA Cyanine 3 System, for 50-150 Slides

TSA® Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.

List Price: 453.00 USD

AR6 buffer, 10X, 4 x 250 mL

10X buffer for use in Opal™ immunohistochemistry multiplexing protocols.

List Price: 195.00 USD

TSA Biotin System, for 50-150 Slides

TSA® biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.

List Price: 354.00 USD

TSA Fluorescein System, for 50-150 Slides

TSA® fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.

List Price: 453.00 USD

TSA Plus Cyanine 3 and Fluorescein System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.

List Price: 734.00 USD

TSA Plus Cyanine 5 and Flourescein System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.

List Price: 734.00 USD

TSA Plus DNP (HRP) System, for 50-150 Slides

TSA® Plus DNP (HRP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP hroseradish peroxidase, with appropriate substrate.

List Price: 477.00 USD

"Tissue Biomarker Reagents" 1-50 of 78 Products and Services