PerkinElmer

Receptor Ligand Binding

OF

Simplify the development of your assays and the calculation of your results using our radioligands, receptor-transfected cell membranes, and cell lines for radioligand binding applications.

Because radioligands can be directly detected, there is no need to generate intermediate antibodies against your target. Eliminating these antibodies also eliminates the need to optimize an antibody titer and reduces your total assay time by skipping intermediate incubation steps.

You’ll find our receptor-ligand binding reagents and related products perfect matches for all of your receptor binding studies.

 

  • Products and Services

  • Resources, Events & More

Narrow your results
Product Type
  • Consumables (2)
  • Instruments (7)
  • Reagents (756)
Application
  • cAMP (26)
  • Drug Discovery & Development (522)
  • Mobility Shift (36)
  • Molecular Biology (2)
  • Plant Sciences (1)
  • Protein Analysis & Detection (2)
  • Protein-protein interactions (2)
Assay Target Class
  • GPCR (182)
  • Ion channel (3)
  • Transporter (6)
  • Tyrosine Kinase Receptor (1)
Assay Validated
  • Binding (216)
  • Calcium Fluorescence (20)
  • cAMP (56)
  • Downstream Phosphorylation (1)
  • GTPγS (54)
  • Inositol Phosphate (15)
Automation Compatible
  • No (22)
  • Yes (40)
Coating Treatment
  • Anti-mouse antibody (2)
  • Anti-mouse IgG (2)
  • Anti-rabbit antibody (2)
  • Anti-rabbit IgG (3)
  • Anti-sheep antibody (1)
  • Anti-sheep IgG (1)
  • Arginine-binding (1)
  • Copper (HIS-tag) (2)
  • Copper chelate (2)
  • Glutathione (6)
  • HIS (2)
  • Membrane-binding (3)
  • Neomycin (1)
  • Nickel chelate (HIS-tag) (2)
  • PDE (3)
  • PEI (19)
  • Poly-L-lysine (3)
  • Poly-lysine (8)
  • Protein A (6)
  • RNA Binding (1)
  • Streptavidin (15)
  • Uncoated (1)
  • WGA (23)
  • WGA PEI type A (1)
  • WGA PEI Type B (1)
Color
  • White (4)
Concentration
  • 1 mCi/mL (5)
  • 1.0 - 10 mCi/mL (86)
  • 1.0 - 10 µCi/mL (3)
  • 1.0 mCi/mL (1)
  • 1.12 mCi/mL (2)
  • 1.14 mCi/mL (1)
  • 13.3 MBq/mL (1)
  • 152 µCi/mL (1)
  • 170.1 µCi/mL (2)
  • 171 µCi/mL (1)
  • 171.9 µCi/mL (2)
  • 172.5 µCi/mL (3)
  • 173.9 µCi/mL (1)
  • 182 µCi/mL (2)
  • 2 mCi/mL (1)
  • 2.93 MBq/mL (2)
  • 236 µCi (3)
  • 3.06 MBq/mL (1)
  • 3.22 MBq/mL (1)
  • 33.7 µCi (2)
  • 345 µCi/mL (4)
  • 353 µCi/mL (5)
  • 41.4 µCi/mL (3)
  • 42.5 µCi/mL (1)
  • 45.7 µCi/mL (2)
  • 50 µCi/mL (1)
  • 6.05 MBq/mL (1)
  • 79.2 µCi/mL (2)
  • 83.8 µCi/mL (1)
  • 85.1 µCi/mL (1)
  • 86.3 µCi (1)
  • 87.2 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 93.2 µCi/mL (2)
  • <1.0 mCi/mL (10)
  • <1.0 µCi/mL (4)
  • <100 µCi/mL (2)
Detection Method
  • DELFIA TRF (4)
  • Filtration (4)
  • Fluorescence (1)
  • Radiometric (466)
  • Time-Resolved Fluorescence (TRF) (4)
Experimental Type
  • In vitro (4)
Fluorophore
  • Eu-N1-ITC (2)
Format
  • Microplates (38)
  • Tubes (30)
Host Cell
  • 1321N1 (13)
  • A431 (1)
  • A9 (1)
  • Balb 3T3 (1)
  • CHO-DHFR(-) (1)
  • CHO-K1 (133)
  • HEK293 (38)
  • HT29 (1)
  • IMR-32 (1)
  • K562 (1)
  • L Cells (1)
  • MDA-MB-435S (1)
  • MDCK (2)
  • U373 (1)
  • UC11 (1)
Label Position
  • Generally Labeled (11)
  • Nominally Labeled (209)
  • Specifically Labeled (167)
  • Uniformly Labeled (1)
Material
  • Barex/GF/B (1)
  • Barex/GF/C (1)
  • Polystyrene/GF/B (1)
  • Polystyrene/GF/C (1)
Number of Wells
  • 96 (4)
Product Brand Name
  • cAMPZen (1)
  • DELFIA (4)
  • LabChip EZ Reader (50)
  • Membrane Target Systems (120)
  • MicroBeta (2)
  • NEN Radiochemicals (203)
  • NEN Radiolabeled Ligands (178)
  • OmniFilter (1)
  • SPA Imaging Beads (22)
  • SPA Scintillation Beads (30)
  • UniFilter (7)
  • ValiScreen (75)
Radionuclide
  • 125I (180)
  • 14C (9)
  • 33P (2)
  • 35S (2)
  • 3H (1)
  • 3H (193)
Radioisotope
  • C-14 (9)
  • H-3 (197)
  • I-125 (181)
  • P-33 (2)
  • S-35 (2)
Receptor Type
  • 5-Hydroxytryptamine (19)
  • 5-Hydroxytryptamine (Serotonin) (23)
  • Acetylcholine (1)
  • Acetylcholine (Muscarinic) (18)
  • Adenosine (17)
  • Adrenergic (13)
  • Adrenoceptors (20)
  • Anaphylatoxin (4)
  • Angiotensin (10)
  • Apelin (4)
  • Benzodiazepine (12)
  • Bombesin (8)
  • Bradykinin (4)
  • Calcitonin (7)
  • Calcium (10)
  • Cannabinoid (10)
  • Chemokine (21)
  • Cholecystokinin (6)
  • Corticotropin-Releasing Factor (3)
  • Dopamine (33)
  • Dopamine Transporter (4)
  • Endothelin (5)
  • Epidermal Growth Factor (5)
  • Formyl Peptide (2)
  • Free Fatty Acid (2)
  • GABA (4)
  • GABAA (12)
  • GABAB (2)
  • Galanin (5)
  • Ghrelin (5)
  • Glucagon (10)
  • Glutamate (13)
  • Glycine (5)
  • Gonadotropin-releasing Hormone (2)
  • Growth Hormone (2)
  • hERG (5)
  • Histamine (11)
  • Insulin (5)
  • Insulin-like Growth Factor (2)
  • Interleukin (4)
  • Leukotriene (3)
  • Melanin-Concentrating Hormone (2)
  • Melanocortin (17)
  • Melatonin (4)
  • Metastin (1)
  • Motilin (2)
  • Muscarinic (10)
  • Neuromedin U (3)
  • Neuropeptide (7)
  • Neuropeptide Y (6)
  • Neurotensin (8)
  • Nicotinic (18)
  • NMDA (1)
  • Norephinephrine (1)
  • Norepinephrine (2)
  • Opioid (25)
  • Orexin (3)
  • Oxytocin (4)
  • Peptide P518 (3)
  • Platelet-Derived Growth Factor (1)
  • Potassium (3)
  • Progestin (1)
  • Prokineticin (1)
  • Prolactin Releasing Peptide (2)
  • Prostanoid (9)
  • Purinergic P2Y (2)
  • Relaxin (3)
  • Retinoic Acid Receptors (1)
  • Serotonin (8)
  • SK channels (2)
  • Sodium (2)
  • Somatostatin (13)
  • SVCT1 (1)
  • SVCT2 (1)
  • Tachykinin (10)
  • Thyroid Hormone (6)
  • Thyrotropin Releasing Hormone (2)
  • Thyrotropin-releasing Hormone (2)
  • Transforming Growth Factor (3)
  • TRPC5 (1)
  • Urotensin (3)
  • Vasoactive Intestinal Peptide (5)
  • Vasopressin (16)
  • Vesicular Amine Transporters (VATs) (1)
Sample Type
  • Enzyme (38)
Target Species
  • Human (6)
Therapeutic Area
  • Angiogenesis (34)
  • Cancer (42)
  • Cardiovascular (163)
  • Central Nervous System (101)
  • CNS & Neurologic (240)
  • Diabetes (29)
  • Gastrointestinal (103)
  • Immune (3)
  • Inflammation (198)
  • Metabolic (54)
  • Metabolic Disorders (78)
  • Musculoskeletal (1)
  • Obesity (15)
  • Pain (111)
  • Parasympathetic Nervous System (5)
  • Renal (2)
  • Sympathetic Nervous System (2)
Volume
  • 0-50 (73)
  • 51-100 (2)
  • 201-250 (63)

"Receptor Ligand Binding" 1-50 of 765 Products and Services

Sort
Per Page

UNIFILTER-96 CELL HARVESTER SS

Speed and simplicity are the primary strengths of the Unifilter Harvester.

OMNIFILTER-96 CELL HARVESTER

Speed and simplicity are the primary strengths of the OmniFilter Harvester.

MICROBETA FILTERMAT-24 CELL HARVESTER

Speed and simplicity are the primary strengths of the FilterMate Harvester. From beginning to end, the FilterMate system is easy to use. Need additional information? Click on the tabs in the product details section below.
LabChip EZ Reader

EZ READER, SHIP LEVEL

The EZ Reader can help to save time and money in your laboratory by identifying the most promising lead candidates faster.

The EZ Reader instrument is available outside the EU. Please contact your local representative for further information.

MICROBETA FILTERMAT-96 CELL HARVESTER

Speed and simplicity are the primary strengths of the FilterMate Harvester. From beginning to end, the FilterMate system is easy to use.

UNIFILTER-24 CELL HARVESTER

Speed and simplicity are the primary strengths of the Unifilter Harvester.

UNIFILTER-96 CELL HARVESTER

Speed and simplicity are the primary strengths of the Unifilter Harvester.
Receptor-expressing cell lines

cAMPZen FroZen cells, Prostanoid EP2, Human Recombinant, HEK293

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 506.00 USD

8-Hydroxy-DPAT, [Propyl-2,3-ring-1,2,3-3H]-, 1mCi (37MBq)

1 mCi quantities of [Propyl-2, 3-ring-1, 2, 3-3H]-8-Hydroxy-DPAT are available for your research.
List Price : 2768.00 USD
List Price : 1197.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 10µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 838.00 USD
Receptor-expressing cell lines

ValiScreen Prostanoid CRTH2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

ProfilerPro Kinase Peptide Substrate 33, for LabChip EZ Reader

Fluorescently-labelled peptide substrate 33 for kinase assays (inhibiton, target discovery, lead optimization)
List Price : 721.00 USD
List Price : 962.00 USD
PerkinElmer

STREP PVT SPECIAL 25 X 500 MG

Streptavidin-coated SPA beads, for capturing biotinylated biomolecules in proximity-based radiometric scintillation assays.
List Price : 63300.00 USD
List Price : 1685.00 USD

RTI-55, [125I]-, 250µCi (9.25MBq)

NEX272 [125I]-RTI-55 is an excellent radioligand for the study of the dopamine transporter sites using either tissue homogenates or autoradiographic methods--especially in regions of low receptor density.
List Price : 1715.00 USD

(-)-CGP-12177, [5,7-3H]-, 25µCi (925kBq)

25 µCi quantities of (-)-CGP-12177, [5,7-3H]- are available for your research.
List Price : 488.00 USD

Flunitrazepam, [Methyl-3H]-, 25µCi (925kBq)

25 µCi quantities of tritiated Flunitrazepam are available for your research.
List Price : 504.00 USD
PerkinElmer

WGA-PEI TYPE A PS 500 MG

WGA-coated SPA beads, for capturing cell membranes in proximity-based scintillation assays.
List Price : 529.00 USD
PerkinElmer

Serotonin Transporter (human) Cell Line

Our stable recombinant cell lines express a variety of receptors for binding and functional assays.
List Price : 17200.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 50µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 2013.00 USD
Receptor-expressing cell lines

ValiScreen Adenosine A2a (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

CGS 21680, [Carboxyethyl-3H(N)]-, 1mCi (37MBq)

1 mCi quantities of [Carboxyethyl-3H(N)]-CGS 21680 are available for your research.
List Price : 4204.00 USD
PerkinElmer

Membrane Target Systems: N-formyl Peptide (FPRL1) (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD
PerkinElmer

ProfilerPro Kinase Peptide Substrate 10, for LabChip EZ Reader

Fluorescently-labelled peptide substrate 10 for kinase assays (inhibiton, target discovery, lead optimization)
List Price : 721.00 USD
PerkinElmer
List Price : 77.00 USD
PerkinElmer

ProfilerPro Kinase Peptide Substrate 32, for LabChip EZ Reader

Fluorescently-labelled peptide substrate 32 for kinase assays (inhibiton, target discovery, lead optimization)
List Price : 721.00 USD

(+/-)Epibatidine, [5,6-Bicycloheptyl-3H]-, 250µCi (9.25MBq)

250 µCi quantities of [+/-] [5, 6-Bicycloheptyl-3H]-Epibatidine are available for your research. 
List Price : 3850.00 USD

DELFIA Eu-Labeling kit (Eu-N1-ITC chelate), 0.2mg

DELFIA® Europium labeling kit for labeling your own biomolecules for use in DELFIA time-resolved fluorescence assays. The ITC chelate reacts with free amine groups in the target biomolecule.
List Price : 526.00 USD
Receptor-expressing cell lines

ValiScreen Dopamine D3 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

ProfilerPro Kinase Peptide Substrate 11, for LabChip EZ Reader

Fluorescently-labelled peptide substrate 11 for kinase assays (inhibiton, target discovery, lead optimization)
List Price : 721.00 USD
PerkinElmer

Membrane Target Systems: Neurotensin NTS1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD
PerkinElmer

WGA YSI 250MG

WGA-coated SPA beads, for capturing cell membranes in proximity-based radiometric scintillation assays.
List Price : 776.00 USD
PerkinElmer

DELFIA® L*R binding buffer concentrate (10x), 250 mL

Buffer for DELFIA® time-resolved fluorescence (TRF) ligand binding assays.
List Price : 532.00 USD

CGRP (human), [125I]-, 50µCi

NEX354 Human CGRP binds to human CGRP receptors in the central nervous system and peripheral nervous system. [125I]-CGRP (human) will be useful in the characterization of CGRP receptors.
List Price : 1840.00 USD
PerkinElmer

Membrane Target Systems: Serotonin 5HT-6 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD

17α-HYDROXYPROGESTERONE, [1,2,6,7-3H]

250 µCi quantities of 17a-Hydroxyprogesterone, [1,2,6,7-3H] are available for your research.
List Price : 1136.00 USD
List Price : 595.00 USD

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 250µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 4574.00 USD
PerkinElmer

Histone 3 Acetylated Peptide, for LabChip EZ Reader

Fluorescently-labelled Histone 3 Peptide (Acetylated) for Epigenetic Assays (Enzyme inhibiton, target discovery, lead optimization)
List Price : 721.00 USD
PerkinElmer

Membrane Target Systems: Vasopressin V2 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human Vasopressin V2 receptor, 400 units.
List Price : 891.00 USD
Receptor-expressing cell lines

ValiScreen Somatostatin sst4 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

ACTH (1-39) 23Tyr [125I], 50 µCi

[125I]ACTH is lyophilized from an acetic acid solution (0.1%) containing bovine serum albumin (0.25%), lactose (5%), L-cysteine hydrochloride (0.1%) and aprotinin (0.3TIU/ml).
List Price : 4474.00 USD
PerkinElmer

Membrane Target Systems: Adenosine A1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 891.00 USD
PerkinElmer

Membrane Target Systems: Vasoactive Intestinal Polypeptide VIP membrane preparation

Cell membranes prepared from HT29 cells containing human endogenous Vasoactive Intestinal Polypeptide (VIP) receptor.
List Price : 933.00 USD

(+)-Pentazocine, [Ring-1,3-3H]-,250µCi (9.25MBq)

250 µCi quantities of [Ring-1, 3-3H]-(+)-Pentazocine are available for your research.
List Price : 1926.00 USD

Batrachotoxinin A 20-α-Benzoate, [Benzoyl-2,5-3H]-, 100µCi (3.7MBq)

Batrachotoxinin A 20-α-Benzoate, [Benzoyl-2,5-3H]- will now be made available on a fresh lot schedule. NET876100UC and NET876250UC will be available as a fresh lot once a year on March 15 in 2017.

"Receptor Ligand Binding" 1-50 of 765 Products and Services

Per Page