PerkinElmer

Protein-protein Interaction Research

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Protein-protein interaction research is uncovering new targets for drug discovery in cancer and a variety of other diseases. However, measurement, modulation, and detection of protein-protein interaction is challenging, and requires technology capable of measuring both high- and low-affinity interactions.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Modulation of protein interactions can affect signal transduction, growth factor, gene expression, and other factors, making it a promising new avenue for protein-based treatment.

Development of protein-based therapeutics requires a thorough understanding of protein function and interactions. Our protein-protein interaction assays and instruments allow fast, multilabel detection of protein-protein interaction for drug discovery.

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1-12 of 116 Products & Services

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  • VictorX_ImageA_320px

    VICTOR Multilabel Plate Reader

    The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
  • EnVision 2105 multimode plate reader

    EnVision 2105 Multimode Plate Reader

    The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

    The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

  • EnSight Multimode Plate Reader

    EnSight Multimode Plate Reader

    The EnSight multimode plate reader combines labeled & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
  • ViewLux uHTS Microplate Imager

    ViewLux uHTS Microplate Imager

    The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

    The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

  • Anti-DIG AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to a mouse monoclonal anti-Dig (digoxin) antibody. These beads can be used to capture Dig-labeled proteins, peptides, and other biomolecules to create AlphaLISA no-wash assays.
    Price Range : 613.00 USD - 25200.00 USD
  • PerkinElmer

    LANCE Eu-W1024 anti-FITC

    Eu-W1024 labeled anti-FITC antibodies for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.
    Price Range : 332.00 USD - 9300.00 USD
  • AlphaLisa Analyte 2

    COX-2 (human), frozen (AlphaLISA)

    Human COX-2 standard, frozen, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human COX-2 Detection Kit, but can be ordered separately.
    List Price : 2899.00 USD
  • Alpha Fc receptor bind

    FCGR3A/CD16a (176Val/V158) AlphaLISA Binding Kit

    This kit is designed for the detection of binding activity between human FCGR3A (176Val) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
    Price Range : 725.00 USD - 11100.00 USD
  • PerkinElmer

    SureLight Allophycocyanin-streptavidin (APC-SA), protein binding assay, Iyophilized

    APC-labeled streptavidin, for use in LANCE® TR-FRET protein binding assays.
    Price Range : 414.00 USD - 11600.00 USD
  • Anti-HA AlphaLISA Acceptor Beads

    AlphaLISA Acceptor beads conjugated to anti-HA (hemagglutinin) antibody. These beads can be used to capture HA-tagged proteins and peptides.
    Price Range : 613.00 USD - 25200.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA Tb-N1 Streptavidin

    Terbium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
    Price Range : 320.00 USD - 2180.00 USD
  • AlphaLISA immunoassay kits

    FcγR2A/CD32a (167H) AlphaLISA Binding Kit

    This kit is designed for the detection of binding between FCGR2A (CD32a) (167H) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
    Price Range : 2213.00 USD - 11100.00 USD
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