PerkinElmer

Protein-protein Interaction Research

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Protein-protein interaction research is uncovering new targets for drug discovery in cancer and a variety of other diseases. However, measurement, modulation, and detection of protein-protein interaction is challenging, and requires technology capable of measuring both high- and low-affinity interactions.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Modulation of protein interactions can affect signal transduction, growth factor, gene expression, and other factors, making it a promising new avenue for protein-based treatment.

Development of protein-based therapeutics requires a thorough understanding of protein function and interactions. Our protein-protein interaction assays and instruments allow fast, multilabel detection of protein-protein interaction for drug discovery.

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  • Accessories (3)
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  • Microplates (82)
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1-12 of 116 Products & Services

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  • VictorX_ImageA_320px

    VICTOR Multilabel Plate Reader

    The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
  • EnSight Multimode Plate Reader

    EnSight Multimode Plate Reader

    The EnSight multimode plate reader combines labeled & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
  • EnVision 2105 multimode plate reader

    EnVision 2105 Multimode Plate Reader

    The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

    The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

  • ViewLux uHTS Microplate Imager

    ViewLux uHTS Microplate Imager

    The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

    The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

  • Assay principle for the AlphaLISA PCSK9/LDLR binding kit

    PCSK9/LDLR (human) AlphaLISA Binding Kit

    This kit is designed to assess binding and inhibition of human PCSK9 and LDLR, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapetics using competition assays.
    Price Range : 2502.00 USD - 17900.00 USD
  • Anti-DNP AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-DNP antibody. These beads can be used to capture DNP-labeled proteins, peptides, and small molecules.
    Price Range : 830.00 USD - 19400.00 USD
  • AlphaLISA immunoassay kits

    COX-2 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human COX-2 enables the detection and quantitation of human COX-2 in cell culture supernatants and cell extracts using a homogeneous AlphaLISA assay (no wash steps). The assay shows no cross-reactivity with human COX-1 nor with sheep COX-2.
    Price Range : 4404.00 USD - 32600.00 USD
  • LANCE Ultra ULight™-anti-6xHis

    Mouse monoclonal anti-polyHistidine tag antibody labeled with ULight™ dye.
    Price Range : 468.00 USD - 11600.00 USD
  • AlphaPlex-545-antibody-bead2

    Anti-FLAG AlphaPlex-545 (Tb) Acceptor beads

    AlphaPlex-545 (Terbium) Acceptor beads conjugated to anti-FLAG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 612.00 USD - 25100.00 USD
  • LANCE Ultra ULight™-Streptavidin

    Streptavidin labeled with ULight™ dye.
    Price Range : 330.00 USD - 6500.00 USD
  • PerkinElmer

    Protein A AlphaPlex™ 545 Acceptor Beads

    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to Protein A, for use in Alpha no-wash multiplexing assays.
    Price Range : 612.00 USD - 25100.00 USD
  • Alpha donor antibody coated

    Anti-HRP Alpha Donor Beads

    Alpha Donor beads conjugated to anti-HRP antibody. These beads can be used to capture HRP-fusion proteins for Alpha no-wash detection, binding, and other assays.
    Price Range : 487.00 USD - 8800.00 USD
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