PerkinElmer

Protein-protein Interaction Research

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Protein-protein interaction research is uncovering new targets for drug discovery in cancer and a variety of other diseases. However, measurement, modulation, and detection of protein-protein interaction is challenging, and requires technology capable of measuring both high- and low-affinity interactions.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Modulation of protein interactions can affect signal transduction, growth factor, gene expression, and other factors, making it a promising new avenue for protein-based treatment.

Development of protein-based therapeutics requires a thorough understanding of protein function and interactions. Our protein-protein interaction assays and instruments allow fast, multilabel detection of protein-protein interaction for drug discovery.

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1-12 of 116 Products & Services

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  • VictorX_ImageA_320px

    VICTOR Multilabel Plate Reader

    The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
  • EnVision 2105 multimode plate reader

    EnVision 2105 Multimode Plate Reader

    The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

    The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

  • EnSight Multimode Plate Reader

    EnSight Multimode Plate Reader

    The EnSight multimode plate reader combines labeled & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
  • ViewLux uHTS Microplate Imager

    ViewLux uHTS Microplate Imager

    The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

    The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

  • PerkinElmer

    LANCE® Eu-W1024 labeled anti-GST antibody

    Europium-labeled anti-GST antibody, for capturing GST-tagged proteins in LANCE® TR-FRET assays.
    Price Range : 220.00 USD - 10900.00 USD
  • Alpha donor antibody coated

    Anti-GFP Alpha Donor Beads

    Alpha Donor beads conjugated to anti-GFP antibody. The antibody is a mouse monoclonal antibody that recognizes wildtype and recombinant GFP (rGFP), and cross-reacts with eGFP. These beads can be used to capture GFP-tagged proteins for AlphaScreen, AlphaLISA, and AlphaPlex no-wash assays.
    Price Range : 638.00 USD - 9200.00 USD
  • PerkinElmer

    LANCE Eu-W1024 Anti-HA

    Europium-labeled anti-HA antibody, for capturing HA-tagged proteins and peptides in LANCE® TR-FRET assays.
    Price Range : 1087.00 USD - 14500.00 USD
  • AlphaPlex-545-antibody-bead2

    Anti-HA AlphaPlex 545 (Tb) Acceptor Beads

    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-HA (hemaglutinin) antibody. These beads can be used to capture HA-tagged proteins and peptides.
    Price Range : 613.00 USD - 25200.00 USD
  • AlphaLisa Analyte 2

    Biotinylated Human FCGR3A (176Val), lyophilized (AlphaLISA)

    Biotinylated human FCGR3A (176Val) receptor. For use in AlphaLISA® no-wash assays.
    List Price : 276.00 USD
  • Anti-GST AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to anti-GST antibody. These beads can be used to capture GST-tagged proteins and peptides in AlphaLISA no-wash assays.
    Price Range : 613.00 USD - 25100.00 USD
  • PerkinElmer

    Protein A AlphaPlex™ 545 Acceptor Beads

    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to Protein A, for use in Alpha no-wash multiplexing assays.
    Price Range : 612.00 USD - 25100.00 USD
  • PerkinElmer

    LANCE Eu-anti-C-tag antibody

    Europium-labeled anti-C-tag antibodies for LANCE® TR-FRET assays. This mouse monoclonal IgG1 antibody recognizes N-terminal and C-terminal Protein C tagged fusion proteins. The anti-C-tag antibody can be used to capture C-tag proteins, and can be used in conjunction with LANCE ULight or SureLight™ APC-labeled reagents to create LANCE TR-FRET assays.
    Price Range : 332.00 USD - 9400.00 USD
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